Patents by Inventor Kazuko Komiya

Kazuko Komiya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5789588
    Abstract: The present invention relates to a carbodiimide derivative represented by the following general formula:W.sub.1 --X--N.dbd.C.dbd.N--Y--W.sub.2 --Zwherein W.sub.1 is a straight chain, branched chain or cyclic saturated or unsaturated aliphatic hydrocarbon group, a substituted or unsubstituted aryl group, a heteroaryl group, a tertiary amino group or a tertiary or quaternary ammonium group; --W.sub.2 --Z is a quaternary ammonium group; X and Y are each independently a single bond or an alkylene group; and Z is a biotin group represented by the following formula: ##STR1## wherein n is 0 or 1. The derivative is useful as a label reagent for introducing a biotin group into a nucleic acid or a protein.
    Type: Grant
    Filed: September 16, 1997
    Date of Patent: August 4, 1998
    Assignee: Nisshinbo Industries, Inc.
    Inventors: Soichiro Takenishi, Osamu Suzuki, Hirohiko Yokomizo, Tatsuo Ichihara, Gen Masuda, Namiko Nakajima, Kazuko Komiya
  • Patent number: 5700935
    Abstract: The present invention relates to a carbodiimide derivative represented by the following general formula:W.sub.1 --X--N.dbd.C.dbd.N--Y--W.sub.2 --Zwherein W.sub.1 is a straight chain, branched chain or cyclic saturated or unsaturated aliphatic hydrocarbon group, a substituted or unsubstituted aryl group, a heteroaryl group, tertiary amino group or a tertiary or quaternary ammonium group; --W.sub.2 --Z is a quaternary ammonium group; X and Y are each independently a single bond or an alkylene group; and Z is a biotin group represented by the following formula: ##STR1## wherein n is 0 or 1. The derivative is useful as a label reagent for introducing a biotin group into a nucleic acid or a protein.
    Type: Grant
    Filed: December 22, 1995
    Date of Patent: December 23, 1997
    Assignee: Nisshinbo Industries, Inc.
    Inventors: Soichiro Takenishi, Osamu Suzuki, Hirohiko Yokomizo, Tatsuo Ichihara, Gen Masuda, Namiko Nakajima, Kazuko Komiya