Patents by Inventor Kazumasa Kinoshita
Kazumasa Kinoshita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 12157070Abstract: In a separation instrument configured to separate a gaseous substance from a solution contained in a container, the separation instrument includes: a first end; a second end; and a side surface provided between the first end and the second end, wherein a plurality of gas introduction grooves configured to swirl a gas and introduce the gas into the container are formed on the side surface between the first end and the second end, and a discharge hole configured to discharge the gaseous substance separated from the solution together with the gas is formed between a center portion of the second end and a center portion of the first end.Type: GrantFiled: October 26, 2021Date of Patent: December 3, 2024Assignee: BIOCHROMATO, INC.Inventors: Kazumasa Kinoshita, Takao Nishiguchi, Tomoaki Endo
-
Publication number: 20230347336Abstract: A container for concentration includes a supplying region in which a swirling flow of a gas is supplied to a solution in the container for concentration, and an avoidance region that is situated below the supplying region and in which supplying of the swirling flow to the solution is avoided.Type: ApplicationFiled: April 24, 2023Publication date: November 2, 2023Inventors: Kazuma MAWATARI, Kazumasa KINOSHITA, Takao NISHIGUCHI, Haruo SHIMADA
-
Publication number: 20230201739Abstract: In a separation instrument configured to separate a gaseous substance from a solution contained in a container, the separation instrument includes: a first end; a second end; and a side surface provided between the first end and the second end, wherein a plurality of gas introduction grooves configured to swirl a gas and introduce the gas into the container are formed on the side surface between the first end and the second end, and a discharge hole configured to discharge the gaseous substance separated from the solution together with the gas is formed between a center portion of the second end and a center portion of the first end.Type: ApplicationFiled: October 26, 2021Publication date: June 29, 2023Inventors: Kazumasa KINOSHITA, Takao NISHIGUCHI, Tomoaki ENDO
-
Publication number: 20230187197Abstract: An ionization device includes an ion formation section configured to ionize an analyte via a corona discharge; and a transfer section configured to transfer the ionized analyte to a mass spectrometry apparatus. The ion formation section and the transfer section are partitioned by one electrode of a pair of electrodes that generate the corona discharge. The one electrode has an opening.Type: ApplicationFiled: August 22, 2022Publication date: June 15, 2023Inventors: Kazumasa KINOSHITA, Takao NISHIGUCHI, Tomoaki ENDO, Kenzo HIRAOKA
-
Patent number: 9779925Abstract: An object of the present invention is to provide a technology that enables highly sensitive atmospheric-pressure real-time mass spectrometry of a volatile substance. The present invention provides a coupling device for a mass spectrometry apparatus that is an interface member to be connected to an atmospheric-pressure real-time mass spectrometry apparatus, the coupling device including (A) an excitation gas introducing port, a sample gas introducing port, and an ionized sample gas discharging port, and (B) a channel through which the excitation gas introducing port and the ionized sample gas discharging port are in communication, and (C) a space for mixing excitation gas and sample gas being formed in a region of a portion of the channel recited in (B), by the coupling device having a structure in which the sample gas introducing port and the channel recited in (B) are in communication.Type: GrantFiled: December 21, 2016Date of Patent: October 3, 2017Assignee: BIOCHROMATO, INC.Inventors: Kazumasa Kinoshita, Yuki Kudo, Takao Nishiguchi
-
Publication number: 20170103878Abstract: An object of the present invention is to provide a technology that enables highly sensitive atmospheric-pressure real-time mass spectrometry of a volatile substance. The present invention provides a coupling device for a mass spectrometry apparatus that is an interface member to be connected to an atmospheric-pressure real-time mass spectrometry apparatus, the coupling device including (A) an excitation gas introducing port, a sample gas introducing port, and an ionized sample gas discharging port, and (B) a channel through which the excitation gas introducing port and the ionized sample gas discharging port are in communication, and (C) a space for mixing excitation gas and sample gas being formed in a region of a portion of the channel recited in (B), by the coupling device having a structure in which the sample gas introducing port and the channel recited in (B) are in communication.Type: ApplicationFiled: December 21, 2016Publication date: April 13, 2017Inventors: Kazumasa Kinoshita, Yuki Kudo, Takao Nishiguchi
-
Patent number: 9595429Abstract: A mass spectrometry method includes a step of atomizing liquid including a sample using an ultrasonic transducer; a step of transferring the atomized liquid; a step of generating ions from the transferred liquid using a DART ion source; and a step of analyzing a mass spectrometry by introducing the generated ions into a mass spectrometer.Type: GrantFiled: April 14, 2014Date of Patent: March 14, 2017Assignees: SHISEIDO COMPANY, LTD., BIO CHROMATO, INC.Inventors: Haruo Shimada, Yuka Morishita, Yoshimasa Nakatani, Kazumasa Kinoshita, Yasuo Shida
-
Patent number: 9570278Abstract: An object of the present invention is to provide a technology that enables highly sensitive atmospheric-pressure real-time mass spectrometry of a volatile substance. The present invention provides a coupling device for a mass spectrometry apparatus that is an interface member to be connected to an atmospheric-pressure real-time mass spectrometry apparatus, the coupling device including (A) an excitation gas introducing port, a sample gas introducing port, and an ionized sample gas discharging port, (B) a channel through which the excitation gas introducing port and the ionized sample gas discharging port are in communication, and (C) a space for mixing excitation gas and sample gas being formed in a region of a portion of the channel recited in (B), by the coupling device having a structure in which the sample gas introducing port and the channel recited in (B) are in communication.Type: GrantFiled: August 3, 2016Date of Patent: February 14, 2017Assignee: BIOCHROMATO, INC.Inventors: Kazumasa Kinoshita, Yuki Kudo, Takao Nishiguchi
-
Publication number: 20160343559Abstract: An object of the present invention is to provide a technology that enables highly sensitive atmospheric-pressure real-time mass spectrometry of a volatile substance. The present invention provides a coupling device for a mass spectrometry apparatus that is an interface member to be connected to an atmospheric-pressure real-time mass spectrometry apparatus, the coupling device including (A) an excitation gas introducing port, a sample gas introducing port, and an ionized sample gas discharging port, (B) a channel through which the excitation gas introducing port and the ionized sample gas discharging port are in communication, and (C) a space for mixing excitation gas and sample gas being formed in a region of a portion of the channel recited in (B), by the coupling device having a structure in which the sample gas introducing port and the channel recited in (B) are in communication.Type: ApplicationFiled: August 3, 2016Publication date: November 24, 2016Inventors: Kazumasa Kinoshita, Yuki Kudo, Takao Nishiguchi
-
Publication number: 20160079050Abstract: A mass spectrometry method includes a step of atomizing liquid including a sample using an ultrasonic transducer; a step of transferring the atomized liquid; a step of generating ions from the transferred liquid using a DART ion source; and a step of analyzing a mass spectrometry by introducing the generated ions into a mass spectrometer.Type: ApplicationFiled: April 14, 2014Publication date: March 17, 2016Inventors: Haruo SHIMADA, Yuka MORISHITA, Yoshimasa NAKATANI, Kazumasa KINOSHITA, Yasuo SHIDA
-
Patent number: 9087680Abstract: An analysis device includes a sample substance spectrum acquisition unit that acquires a plurality of sample substance spectra obtained a plurality of times for a sample substance; a storage unit that stores a plurality of reference spectra for a known substance; a first evaluation value calculation unit that calculates a first evaluation value for a combination of a sample substance spectrum and a reference spectrum extracted from the plurality of sample substance spectra and the plurality of reference spectra, the first evaluation value representing a similarity between a peak intensity ratio of the reference spectrum and a peak intensity ratio of a portion of the sample substance spectrum corresponding to a peak in the reference spectrum; and a second evaluation value calculation unit that calculates a second evaluation value representing a similarity between the sample substance and the known substance based on the first evaluation values for the combinations.Type: GrantFiled: August 30, 2012Date of Patent: July 21, 2015Assignees: SHISEIDO COMPANY, LTD., BIO CHROMATO, INC.Inventors: Haruo Shimada, Yoshimasa Nakatani, Yuka Morishita, Kazumasa Kinoshita, Tomohiro Sakuma, Yasuto Yokoi
-
Patent number: 8927926Abstract: A mass spectrometry method of the present invention is such that a sample is heated to generate a gas and an ion that is produced from the gas is introduced into a mass spectrometer by using DART so that mass spectrometry is conducted.Type: GrantFiled: December 26, 2011Date of Patent: January 6, 2015Assignees: Shiseido Company, Ltd., Bio Chromato, Inc.Inventors: Haruo Shimada, Yoshimasa Nakatani, Yuka Noritake, Kazumasa Kinoshita, Yasuo Shida
-
Publication number: 20140215820Abstract: An inner hole to which a driving shaft is inserted is formed in a cam piece of a camshaft, and a plurality of grooves extending in the insertion direction of the driving shaft are formed in the inner hole. The driving shaft is inserted into the inner hole with the cam piece heated to expand the diameter of the inner hole. By reducing again the diameter of the inner hole by cooling it in this state, an outer circumferential surface of the driving shaft is pressed and raised by the inner hole and enters the groove, by which the cam piece is firmly fixed onto the driving shaft.Type: ApplicationFiled: April 10, 2014Publication date: August 7, 2014Applicants: OTICS CORPORATION, FINE SINTER CO., LTD.Inventors: Tamotsu YAMAMOTO, Eiji ISOGAI, Kazumasa KINOSHITA, Kunihiro NISHIMURA, Hidekazu SATO
-
Publication number: 20140183353Abstract: An analysis device includes a sample substance spectrum acquisition unit that acquires a plurality of sample substance spectra obtained a plurality of times for a sample substance; a storage unit that stores a plurality of reference spectra for a known substance; a first evaluation value calculation unit that calculates a first evaluation value for a combination of a sample substance spectrum and a reference spectrum extracted from the plurality of sample substance spectra and the plurality of reference spectra, the first evaluation value representing a similarity between a peak intensity ratio of the reference spectrum and a peak intensity ratio of a portion of the sample substance spectrum corresponding to a peak in the reference spectrum; and a second evaluation value calculation unit that calculates a second evaluation value representing a similarity between the sample substance and the known substance based on the first evaluation values for the combinations.Type: ApplicationFiled: August 30, 2012Publication date: July 3, 2014Applicant: SHISEIDO COMPANY, LTD., Tokyo, Japan and Bio Chromato, Inc.,Inventors: Haruo Shimada, Yoshimasa Nakatani, Yuka Morishita, Kazumasa Kinoshita, Tomohiro Sakuma, Yasuto Yokoi
-
Publication number: 20130299692Abstract: A mass spectrometry method of the present invention is such that a sample is heated to generate a gas and an ion that is produced from the gas is introduced into a mass spectrometer by using DART so that mass spectrometry is conducted.Type: ApplicationFiled: December 26, 2011Publication date: November 14, 2013Applicants: Bio Chromato, Inc., SHISEIDO COMPANY, LTD.Inventors: Haruo Shimada, Yoshimasa Nakatani, Yuka Noritake, Kazumasa Kinoshita, Yasuo Shida
-
Publication number: 20130284915Abstract: A mass spectrometry method of the present invention is a method for conducting mass spectrometry in such a manner that an ion that is produced from a sample is introduced into a mass spectrometer by using DART or DESI, wherein the mass spectrometer has an ion introduction part for introducing the ion thereinto and the ion introduction part is heated at a predetermined timing.Type: ApplicationFiled: December 26, 2011Publication date: October 31, 2013Applicants: Bio Chromato, Inc., SHISEIDO COMPANY, LTD.Inventors: Haruo Shimada, Yoshimasa Nakatani, Yuka Noritake, Kazumasa Kinoshita, Yasuo Shida
-
Patent number: 8043685Abstract: The object of the present invention is to provide a sheet applicable for closing an opening of a liquid dispensing container for a liquid handling system used in chemical experiments, in which the sheet is capable of preventing natural volatilization of a liquid in the container even if the tip is frequently inserted and drawn, and also facilitating inserting and drawing of the tip. The composite sheet of the present invention comprises a sheet having elastic property and another sheet having slip property wherein the sheets are stacked. The composite sheet of the present invention can be used to close an opening of a liquid dispensing container for a liquid handling system used in chemical experiments. It can prevent volatilization of the solvent, and also facilitate inserting and drawing of the tip.Type: GrantFiled: March 28, 2005Date of Patent: October 25, 2011Assignee: Chugai Seikaku KabushikikaishaInventors: Kiyoshi Yoshinari, Hideo Shimura, Kazumasa Kinoshita
-
Publication number: 20100012278Abstract: A vessel 1 comprises a container 2 for storing a sample solution containing a volatile substance and a stopper 3. The stopper 3 is formed with a through-pore 3a at the center, through which a vaporized volatile substance is discharged with exhaust gas. The stopper 2 is formed with a gas inlet port 3b and a gas outlet port 3c at the upper and lower edges, respectively, and a groove 3d connecting the both ports 3b and 3c at the side surface. On reducing pressure in the container 2, an external gas is blown into the container 2 from the gas outlet port 3c through the groove 3d at high speed and spirally rotates by centrifugal force along the inner wall of the container 2. This kicks up the sample solution to stir it, increasing the surface area of the solution and thus promoting vaporizing of the volatile substance.Type: ApplicationFiled: December 26, 2007Publication date: January 21, 2010Inventors: Takashi Ohnuki, Mutsuo Nakajima, Kazumasa Kinoshita
-
Publication number: 20080250895Abstract: An inner hole 31 to which a driving shaft 2 is inserted is formed in a campiece 3 of a camshaft 1, and a plurality of grooves 34 extending in the insertion direction of the driving shaft 2 are formed in the inner hole 31. The driving shaft 2 is inserted into the inner hole 31 with the cam piece 3 heated to expand the diameter of the inner hole 31. By reducing again the diameter of the inner hole 31 by cooling it in this state, an outer circumferential surface of the driving shaft 2 is pressed and raised by the inner hole 31 and enters the groove 34, by which the cam piece 3 is firmly fixed onto the driving shaft 2.Type: ApplicationFiled: January 19, 2006Publication date: October 16, 2008Inventors: Tamotsu Yamamoto, Eiji Isogai, Kazumasa Kinoshita, Kunihiro Nishimura, Hidekazu Sato
-
Publication number: 20080210691Abstract: The object of the present invention is to provide a sheet applicable for closing an opening of a liquid dispensing container for a liquid handling system used in chemical experiments, in which the sheet is capable of preventing natural volatilization of a liquid in the container even if the tip is frequently inserted and drawn, and also facilitating inserting and drawing of the tip. The composite. sheet of the present invention comprises a sheet having elastic property and another sheet having slip property wherein the sheets are stacked. The composite sheet of the present invention can be used to close an opening of a liquid dispensing container for a liquid handling system used in chemical experiments. It can prevent volatilization of the solvent, and also facilitate inserting and drawing of the tip.Type: ApplicationFiled: March 28, 2005Publication date: September 4, 2008Applicant: Chugai Seiyaku KabushikikaishaInventors: Kiyoshi Yoshinari, Hideo Shimura, Kazumasa Kinoshita