Patents by Inventor Kazumasa Kinoshita

Kazumasa Kinoshita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230347336
    Abstract: A container for concentration includes a supplying region in which a swirling flow of a gas is supplied to a solution in the container for concentration, and an avoidance region that is situated below the supplying region and in which supplying of the swirling flow to the solution is avoided.
    Type: Application
    Filed: April 24, 2023
    Publication date: November 2, 2023
    Inventors: Kazuma MAWATARI, Kazumasa KINOSHITA, Takao NISHIGUCHI, Haruo SHIMADA
  • Publication number: 20230201739
    Abstract: In a separation instrument configured to separate a gaseous substance from a solution contained in a container, the separation instrument includes: a first end; a second end; and a side surface provided between the first end and the second end, wherein a plurality of gas introduction grooves configured to swirl a gas and introduce the gas into the container are formed on the side surface between the first end and the second end, and a discharge hole configured to discharge the gaseous substance separated from the solution together with the gas is formed between a center portion of the second end and a center portion of the first end.
    Type: Application
    Filed: October 26, 2021
    Publication date: June 29, 2023
    Inventors: Kazumasa KINOSHITA, Takao NISHIGUCHI, Tomoaki ENDO
  • Publication number: 20230187197
    Abstract: An ionization device includes an ion formation section configured to ionize an analyte via a corona discharge; and a transfer section configured to transfer the ionized analyte to a mass spectrometry apparatus. The ion formation section and the transfer section are partitioned by one electrode of a pair of electrodes that generate the corona discharge. The one electrode has an opening.
    Type: Application
    Filed: August 22, 2022
    Publication date: June 15, 2023
    Inventors: Kazumasa KINOSHITA, Takao NISHIGUCHI, Tomoaki ENDO, Kenzo HIRAOKA
  • Patent number: 9779925
    Abstract: An object of the present invention is to provide a technology that enables highly sensitive atmospheric-pressure real-time mass spectrometry of a volatile substance. The present invention provides a coupling device for a mass spectrometry apparatus that is an interface member to be connected to an atmospheric-pressure real-time mass spectrometry apparatus, the coupling device including (A) an excitation gas introducing port, a sample gas introducing port, and an ionized sample gas discharging port, and (B) a channel through which the excitation gas introducing port and the ionized sample gas discharging port are in communication, and (C) a space for mixing excitation gas and sample gas being formed in a region of a portion of the channel recited in (B), by the coupling device having a structure in which the sample gas introducing port and the channel recited in (B) are in communication.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: October 3, 2017
    Assignee: BIOCHROMATO, INC.
    Inventors: Kazumasa Kinoshita, Yuki Kudo, Takao Nishiguchi
  • Publication number: 20170103878
    Abstract: An object of the present invention is to provide a technology that enables highly sensitive atmospheric-pressure real-time mass spectrometry of a volatile substance. The present invention provides a coupling device for a mass spectrometry apparatus that is an interface member to be connected to an atmospheric-pressure real-time mass spectrometry apparatus, the coupling device including (A) an excitation gas introducing port, a sample gas introducing port, and an ionized sample gas discharging port, and (B) a channel through which the excitation gas introducing port and the ionized sample gas discharging port are in communication, and (C) a space for mixing excitation gas and sample gas being formed in a region of a portion of the channel recited in (B), by the coupling device having a structure in which the sample gas introducing port and the channel recited in (B) are in communication.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Inventors: Kazumasa Kinoshita, Yuki Kudo, Takao Nishiguchi
  • Patent number: 9595429
    Abstract: A mass spectrometry method includes a step of atomizing liquid including a sample using an ultrasonic transducer; a step of transferring the atomized liquid; a step of generating ions from the transferred liquid using a DART ion source; and a step of analyzing a mass spectrometry by introducing the generated ions into a mass spectrometer.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: March 14, 2017
    Assignees: SHISEIDO COMPANY, LTD., BIO CHROMATO, INC.
    Inventors: Haruo Shimada, Yuka Morishita, Yoshimasa Nakatani, Kazumasa Kinoshita, Yasuo Shida
  • Patent number: 9570278
    Abstract: An object of the present invention is to provide a technology that enables highly sensitive atmospheric-pressure real-time mass spectrometry of a volatile substance. The present invention provides a coupling device for a mass spectrometry apparatus that is an interface member to be connected to an atmospheric-pressure real-time mass spectrometry apparatus, the coupling device including (A) an excitation gas introducing port, a sample gas introducing port, and an ionized sample gas discharging port, (B) a channel through which the excitation gas introducing port and the ionized sample gas discharging port are in communication, and (C) a space for mixing excitation gas and sample gas being formed in a region of a portion of the channel recited in (B), by the coupling device having a structure in which the sample gas introducing port and the channel recited in (B) are in communication.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: February 14, 2017
    Assignee: BIOCHROMATO, INC.
    Inventors: Kazumasa Kinoshita, Yuki Kudo, Takao Nishiguchi
  • Publication number: 20160343559
    Abstract: An object of the present invention is to provide a technology that enables highly sensitive atmospheric-pressure real-time mass spectrometry of a volatile substance. The present invention provides a coupling device for a mass spectrometry apparatus that is an interface member to be connected to an atmospheric-pressure real-time mass spectrometry apparatus, the coupling device including (A) an excitation gas introducing port, a sample gas introducing port, and an ionized sample gas discharging port, (B) a channel through which the excitation gas introducing port and the ionized sample gas discharging port are in communication, and (C) a space for mixing excitation gas and sample gas being formed in a region of a portion of the channel recited in (B), by the coupling device having a structure in which the sample gas introducing port and the channel recited in (B) are in communication.
    Type: Application
    Filed: August 3, 2016
    Publication date: November 24, 2016
    Inventors: Kazumasa Kinoshita, Yuki Kudo, Takao Nishiguchi
  • Publication number: 20160079050
    Abstract: A mass spectrometry method includes a step of atomizing liquid including a sample using an ultrasonic transducer; a step of transferring the atomized liquid; a step of generating ions from the transferred liquid using a DART ion source; and a step of analyzing a mass spectrometry by introducing the generated ions into a mass spectrometer.
    Type: Application
    Filed: April 14, 2014
    Publication date: March 17, 2016
    Inventors: Haruo SHIMADA, Yuka MORISHITA, Yoshimasa NAKATANI, Kazumasa KINOSHITA, Yasuo SHIDA
  • Patent number: 9087680
    Abstract: An analysis device includes a sample substance spectrum acquisition unit that acquires a plurality of sample substance spectra obtained a plurality of times for a sample substance; a storage unit that stores a plurality of reference spectra for a known substance; a first evaluation value calculation unit that calculates a first evaluation value for a combination of a sample substance spectrum and a reference spectrum extracted from the plurality of sample substance spectra and the plurality of reference spectra, the first evaluation value representing a similarity between a peak intensity ratio of the reference spectrum and a peak intensity ratio of a portion of the sample substance spectrum corresponding to a peak in the reference spectrum; and a second evaluation value calculation unit that calculates a second evaluation value representing a similarity between the sample substance and the known substance based on the first evaluation values for the combinations.
    Type: Grant
    Filed: August 30, 2012
    Date of Patent: July 21, 2015
    Assignees: SHISEIDO COMPANY, LTD., BIO CHROMATO, INC.
    Inventors: Haruo Shimada, Yoshimasa Nakatani, Yuka Morishita, Kazumasa Kinoshita, Tomohiro Sakuma, Yasuto Yokoi
  • Patent number: 8927926
    Abstract: A mass spectrometry method of the present invention is such that a sample is heated to generate a gas and an ion that is produced from the gas is introduced into a mass spectrometer by using DART so that mass spectrometry is conducted.
    Type: Grant
    Filed: December 26, 2011
    Date of Patent: January 6, 2015
    Assignees: Shiseido Company, Ltd., Bio Chromato, Inc.
    Inventors: Haruo Shimada, Yoshimasa Nakatani, Yuka Noritake, Kazumasa Kinoshita, Yasuo Shida
  • Publication number: 20140215820
    Abstract: An inner hole to which a driving shaft is inserted is formed in a cam piece of a camshaft, and a plurality of grooves extending in the insertion direction of the driving shaft are formed in the inner hole. The driving shaft is inserted into the inner hole with the cam piece heated to expand the diameter of the inner hole. By reducing again the diameter of the inner hole by cooling it in this state, an outer circumferential surface of the driving shaft is pressed and raised by the inner hole and enters the groove, by which the cam piece is firmly fixed onto the driving shaft.
    Type: Application
    Filed: April 10, 2014
    Publication date: August 7, 2014
    Applicants: OTICS CORPORATION, FINE SINTER CO., LTD.
    Inventors: Tamotsu YAMAMOTO, Eiji ISOGAI, Kazumasa KINOSHITA, Kunihiro NISHIMURA, Hidekazu SATO
  • Publication number: 20140183353
    Abstract: An analysis device includes a sample substance spectrum acquisition unit that acquires a plurality of sample substance spectra obtained a plurality of times for a sample substance; a storage unit that stores a plurality of reference spectra for a known substance; a first evaluation value calculation unit that calculates a first evaluation value for a combination of a sample substance spectrum and a reference spectrum extracted from the plurality of sample substance spectra and the plurality of reference spectra, the first evaluation value representing a similarity between a peak intensity ratio of the reference spectrum and a peak intensity ratio of a portion of the sample substance spectrum corresponding to a peak in the reference spectrum; and a second evaluation value calculation unit that calculates a second evaluation value representing a similarity between the sample substance and the known substance based on the first evaluation values for the combinations.
    Type: Application
    Filed: August 30, 2012
    Publication date: July 3, 2014
    Applicant: SHISEIDO COMPANY, LTD., Tokyo, Japan and Bio Chromato, Inc.,
    Inventors: Haruo Shimada, Yoshimasa Nakatani, Yuka Morishita, Kazumasa Kinoshita, Tomohiro Sakuma, Yasuto Yokoi
  • Publication number: 20130299692
    Abstract: A mass spectrometry method of the present invention is such that a sample is heated to generate a gas and an ion that is produced from the gas is introduced into a mass spectrometer by using DART so that mass spectrometry is conducted.
    Type: Application
    Filed: December 26, 2011
    Publication date: November 14, 2013
    Applicants: Bio Chromato, Inc., SHISEIDO COMPANY, LTD.
    Inventors: Haruo Shimada, Yoshimasa Nakatani, Yuka Noritake, Kazumasa Kinoshita, Yasuo Shida
  • Publication number: 20130284915
    Abstract: A mass spectrometry method of the present invention is a method for conducting mass spectrometry in such a manner that an ion that is produced from a sample is introduced into a mass spectrometer by using DART or DESI, wherein the mass spectrometer has an ion introduction part for introducing the ion thereinto and the ion introduction part is heated at a predetermined timing.
    Type: Application
    Filed: December 26, 2011
    Publication date: October 31, 2013
    Applicants: Bio Chromato, Inc., SHISEIDO COMPANY, LTD.
    Inventors: Haruo Shimada, Yoshimasa Nakatani, Yuka Noritake, Kazumasa Kinoshita, Yasuo Shida
  • Patent number: 8043685
    Abstract: The object of the present invention is to provide a sheet applicable for closing an opening of a liquid dispensing container for a liquid handling system used in chemical experiments, in which the sheet is capable of preventing natural volatilization of a liquid in the container even if the tip is frequently inserted and drawn, and also facilitating inserting and drawing of the tip. The composite sheet of the present invention comprises a sheet having elastic property and another sheet having slip property wherein the sheets are stacked. The composite sheet of the present invention can be used to close an opening of a liquid dispensing container for a liquid handling system used in chemical experiments. It can prevent volatilization of the solvent, and also facilitate inserting and drawing of the tip.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: October 25, 2011
    Assignee: Chugai Seikaku Kabushikikaisha
    Inventors: Kiyoshi Yoshinari, Hideo Shimura, Kazumasa Kinoshita
  • Publication number: 20100012278
    Abstract: A vessel 1 comprises a container 2 for storing a sample solution containing a volatile substance and a stopper 3. The stopper 3 is formed with a through-pore 3a at the center, through which a vaporized volatile substance is discharged with exhaust gas. The stopper 2 is formed with a gas inlet port 3b and a gas outlet port 3c at the upper and lower edges, respectively, and a groove 3d connecting the both ports 3b and 3c at the side surface. On reducing pressure in the container 2, an external gas is blown into the container 2 from the gas outlet port 3c through the groove 3d at high speed and spirally rotates by centrifugal force along the inner wall of the container 2. This kicks up the sample solution to stir it, increasing the surface area of the solution and thus promoting vaporizing of the volatile substance.
    Type: Application
    Filed: December 26, 2007
    Publication date: January 21, 2010
    Inventors: Takashi Ohnuki, Mutsuo Nakajima, Kazumasa Kinoshita
  • Publication number: 20080250895
    Abstract: An inner hole 31 to which a driving shaft 2 is inserted is formed in a campiece 3 of a camshaft 1, and a plurality of grooves 34 extending in the insertion direction of the driving shaft 2 are formed in the inner hole 31. The driving shaft 2 is inserted into the inner hole 31 with the cam piece 3 heated to expand the diameter of the inner hole 31. By reducing again the diameter of the inner hole 31 by cooling it in this state, an outer circumferential surface of the driving shaft 2 is pressed and raised by the inner hole 31 and enters the groove 34, by which the cam piece 3 is firmly fixed onto the driving shaft 2.
    Type: Application
    Filed: January 19, 2006
    Publication date: October 16, 2008
    Inventors: Tamotsu Yamamoto, Eiji Isogai, Kazumasa Kinoshita, Kunihiro Nishimura, Hidekazu Sato
  • Publication number: 20080210691
    Abstract: The object of the present invention is to provide a sheet applicable for closing an opening of a liquid dispensing container for a liquid handling system used in chemical experiments, in which the sheet is capable of preventing natural volatilization of a liquid in the container even if the tip is frequently inserted and drawn, and also facilitating inserting and drawing of the tip. The composite. sheet of the present invention comprises a sheet having elastic property and another sheet having slip property wherein the sheets are stacked. The composite sheet of the present invention can be used to close an opening of a liquid dispensing container for a liquid handling system used in chemical experiments. It can prevent volatilization of the solvent, and also facilitate inserting and drawing of the tip.
    Type: Application
    Filed: March 28, 2005
    Publication date: September 4, 2008
    Applicant: Chugai Seiyaku Kabushikikaisha
    Inventors: Kiyoshi Yoshinari, Hideo Shimura, Kazumasa Kinoshita
  • Patent number: 4690581
    Abstract: A ball joint is disclosed having a socket, a ball received by the socket and a stud extending outwardly from the ball. A ball seat member is received in the socket and has a soft portion with an inner spherical surface which covers the portion of the ball at the side opposite to the stud. The soft portion is axially compressed by a cap closing an opening in the socket opposite to the stud, while expanding radially outward to be penetrated by linear projections formed in a hard portion of the ball seat member. Further, a gap remains between the soft portion after it has expanded radially outwardly and the inner cylindrical surface of the hard portion of the ball seat member so that the soft portion of the ball seat member contacts the hard portion of the ball seat member only at the linear projections.
    Type: Grant
    Filed: May 10, 1985
    Date of Patent: September 1, 1987
    Assignees: Toyota Jidosha Kabushiki Kaisha, Odai Tekko Kabushiki Kaisha
    Inventors: Yonetsugu Umemoto, Hiroshi Shirasawa, Muneya Ogo, Kazumasa Kinoshita, Tetsuo Kondo