Patents by Inventor Kazumichi Jo

Kazumichi Jo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUCCINATE SALTS OF OCTAHYDROTHIENOQUINOLINE COMPOUND AND CRYSTALS THEREOF
    Publication number: 20230286998
    Abstract: An object of the present invention is to provide a compound which has high storage stability and is suitable for use as a drug substance. The present invention relates to a succinate salt of 1-{[(4aR,6R,8aR)-2-amino-3-cyano-8-methyl-4,4a,5,6,7,8,8a,9-octahydrothieno[3,2-g]quinolin-6-yl]carbonyl}-3-[2-(dimethylamino)ethyl]-1-propylurea, which is suitable as a drug substance having excellent storage stability and crystallinity and is useful for the treatment or prevention of Parkinson's disease, restless legs syndrome, hyperprolactinemia or the like.
    Type: Application
    Filed: July 5, 2021
    Publication date: September 14, 2023
    Applicant: KISSEI PHARMACEUTICAL CO., LTD.
    Inventors: Hideki TAKEUCHI, Kazumichi JO
  • SALT OF FUSED HETEROCYCLIC DERIVATIVE AND CRYSTAL THEREOF
    Publication number: 20200390768
    Abstract: The present invention provides 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyl-oxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid choline salt having excellent solubility and storage stability.
    Type: Application
    Filed: January 21, 2020
    Publication date: December 17, 2020
    Applicant: KISSEI PHARMACEUTICAL CO., LTD.
    Inventors: Kazumichi JO, Hideki TAKEUCHI
  • Salt of fused heterocyclic derivative and crystal thereof
    Patent number: 10576084
    Abstract: The present invention provides 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyl-oxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid choline salt having excellent solubility and storage stability.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: March 3, 2020
    Assignee: KISSEI PHARMACEUTICAL CO., LTD.
    Inventors: Kazumichi Jo, Hideki Takeuchi
  • SALT OF FUSED HETEROCYCLIC DERIVATIVE AND CRYSTAL THEREOF
    Publication number: 20190134038
    Abstract: The present invention provides 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyl-oxy)-4-methoxyphenyl]-2,4-dioxo- 1,2,3,4-tetrahydrothieno [3 ,4-d]pyrimidine-5-carboxylic acid choline salt having excellent solubility and storage stability.
    Type: Application
    Filed: June 27, 2018
    Publication date: May 9, 2019
    Applicant: KISSEI PHARMACEUTICAL CO., LTD.
    Inventors: Kazumichi JO, Hideki TAKEUCHI
  • Salt of fused heterocyclic derivative and crystal thereof
    Patent number: 10016433
    Abstract: The present invention provides 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyl-oxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid choline salt having excellent solubility and storage stability.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: July 10, 2018
    Assignee: KISSEI PHARMACEUTICAL CO., LTD.
    Inventors: Kazumichi Jo, Hideki Takeuchi
  • SALT OF FUSED HETEROCYCLIC DERIVATIVE AND CRYSTAL THEREOF
    Publication number: 20170319588
    Abstract: The present invention provides 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyl-oxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid choline salt having excellent solubility and storage stability.
    Type: Application
    Filed: July 12, 2017
    Publication date: November 9, 2017
    Applicant: KISSEI PHARMACEUTICAL CO., LTD.
    Inventors: Kazumichi JO, Hideki TAKEUCHI
  • Salt of fused heterocyclic derivative and crystal thereof
    Patent number: 9737539
    Abstract: The present invention provides 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyloxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid choline salt having excellent solubility and storage stability.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: August 22, 2017
    Assignee: KISSEI PHARMACEUTICALS CO., LTD.
    Inventors: Kazumichi Jo, Hideki Takeuchi
  • SALT OF FUSED HETEROCYCLIC DERIVATIVE AND CRYSTAL THEREOF
    Publication number: 20160082010
    Abstract: An objective of the present invention is to improve the solubility of 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyloxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid. The present invention provides 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyl-oxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid choline salt has excellent solubility and storage stability.
    Type: Application
    Filed: September 28, 2015
    Publication date: March 24, 2016
    Applicant: KISSEI PHARMACEUTICAL CO., LTD.
    Inventors: Kazumichi JO, Hideki TAKEUCHI
  • Salt of fused heterocyclic derivative and crystal thereof
    Patent number: 9169266
    Abstract: An objective of the present invention is to improve the solubility of 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyloxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid. The present invention provides 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyl-oxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid choline salt has excellent solubility and storage stability.
    Type: Grant
    Filed: February 9, 2011
    Date of Patent: October 27, 2015
    Assignee: KISSEI PHARMACEUTICAL CO., LTD.
    Inventors: Kazumichi Jo, Hideki Takeuchi
  • SALT OF FUSED HETEROCYCLIC DERIVATIVE AND CRYSTAL THEREOF
    Publication number: 20130059867
    Abstract: An objective of the present invention is to improve the solubility of 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyloxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid. The present invention provides 342-fluoro-5-(2,3-difluoro-6-methoxybenzyl-oxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid choline salt has excellent solubility and storage stability.
    Type: Application
    Filed: February 9, 2011
    Publication date: March 7, 2013
    Applicant: Kissei Pharmaceutical Co., Ltd.
    Inventors: Kazumichi Jo, Hideki Takeuchi