Patents by Inventor Kazumichi Yamamoto
Kazumichi Yamamoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8900638Abstract: The present invention provides a solid preparation containing compound (I) [compound (I) is as defined in the specification] or a salt thereof, and metformin hydrochloride, which is useful as a therapeutic drug for diabetes and the like, and superior in the preservation stability. A solid preparation having a first part and a second part: a first part: a part containing compound (I) or a salt thereof and substantially free of metformin hydrochloride a second part: a part containing metformin hydrochloride and substantially free of compound (I) and a salt thereof.Type: GrantFiled: July 16, 2008Date of Patent: December 2, 2014Assignee: Takeda Pharmaceutical Company LimitedInventors: Kazumichi Yamamoto, Hiroyoshi Koyama
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Patent number: 8815801Abstract: A controlled release composition containing a physiologically active substance in high content, suppressing the initial excess release, and achieving a stable release speed over a long period of time is provided. A controlled release composition comprising (1) a physiologically active substance or salt thereof in an amount of about 14% (w/w) to about 24% (w/w) based on the total composition weight, (2) hydroxynaphthoic acid selected from the group consisting of 3-hydroxy-2-naphthoic acid and 1-hydroxy-2-naphthoic acid or salt thereof, and (3) a lactic acid polymer or salt thereof having a weight-average molecular weight of 15000 to 50000 in which the content of polymers having molecular weights of 5000 or less is about 5% by weight or less, wherein the molar ratio of said hydroxynaphthoic acid or salt thereof to said physiologically active substance or salt thereof is from 3:4 to 4:3.Type: GrantFiled: July 13, 2012Date of Patent: August 26, 2014Assignee: Takeda Pharmaceutical Company LimitedInventors: Kazumichi Yamamoto, Akiko Yamada, Yoshio Hata
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Publication number: 20140205672Abstract: A controlled release composition for oral administration, which comprises a physiologically active substance which is a compound represented by the formula: wherein n is an integer of 1 to 3, and Ar is an aromatic ring which may be substituted, or a salt thereof, and a hydrophilic polymer, or a controlled release composition for oral administration, wherein a core containing the physiologically active substance is coated with a coating layer containing a polymer, is provided.Type: ApplicationFiled: January 17, 2014Publication date: July 24, 2014Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Shigeo Yanai, Kazumichi Yamamoto
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Publication number: 20120295848Abstract: Present invention is to provide a sustained-release composition which contains a physiologically active substance in high content even when gelatin is not included, and suppresses its initial excessive release and, thus, can achieve a stable release rate over about one month. A sustained-release composition containing a lactic acid-glycolic acid polymer having a ratio or weight average molecular weight and number average molecular weight of about 1.90 or lower, or a salt thereof, and a physiologically active substance.Type: ApplicationFiled: August 2, 2012Publication date: November 22, 2012Inventors: Kazumichi Yamamoto, Akiko YAMADA, Yoshio HATA
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Publication number: 20120283187Abstract: A controlled release composition containing a physiologically active substance in high content, suppressing the initial excess release, and achieving a stable release speed over a long period of time is provided. A controlled release composition comprising (1) a physiologically active substance or salt thereof in an amount of about 14% (w/w) to about 24% (w/w) based on the total composition weight, (2) hydroxynaphthoic acid selected from the group consisting of 3-hydroxy-2-naphthoic acid and 1-hydroxy-2-naphthoic acid or salt thereof, and (3) a lactic acid polymer or salt thereof having a weight-average molecular weight of 15000 to 50000 in which the content of polymers having molecular weights of 5000 or less is about 5% by weight or less, wherein the molar ratio of said hydroxynaphthoic acid or salt thereof to said physiologically active substance or salt thereof is from 3:4 to 4:3.Type: ApplicationFiled: July 13, 2012Publication date: November 8, 2012Inventors: Kazumichi Yamamoto, Akiko Yamada, Yoshio Hata
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Patent number: 8246987Abstract: A controlled release composition containing a physiologically active substance in high content, suppressing the initial excess release, and achieving a stable release speed over a long period of time is provided. A controlled release composition comprising (1) a physiologically active substance or salt thereof in an amount of about 14% (w/w) to about 24% (w/w) based on the total composition weight, (2) hydroxynaphthoic acid selected from the group consisting of 3-hydroxy-2-naphthoic acid and 1-hydroxy-2-naphthoic acid or salt thereof, and (3) a lactic acid polymer or salt thereof having a weight-average molecular weight of 15000 to 50000 in which the content of polymers having molecular weights of 5000 or less is about 5% by weight or less, wherein the molar ratio of said hydroxynaphthoic acid or salt thereof to said physiologically active substance or salt thereof is from 3:4 to 4:3.Type: GrantFiled: March 16, 2011Date of Patent: August 21, 2012Assignee: Takeda Pharmaceutical Company LimitedInventors: Kazumichi Yamamoto, Akiko Yamada, Yoshio Hata
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Patent number: 8088726Abstract: A process for producing a sustained-release composition which comprises mixing an aqueous solution containing a physiologically active substance and an acid or base in a molar amount of 1.5 or more times that of the physiologically active substance with a solution of a biodegradable polymer and then drying the mixture is provided.Type: GrantFiled: June 24, 2003Date of Patent: January 3, 2012Assignee: Takeda Pharmaceutical Company LimitedInventors: Kazumichi Yamamoto, Kazuhiro Saito, Tetsuo Hoshino
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Patent number: 8067030Abstract: A controlled release composition containing a physiologically active substance in high content, suppressing the initial excess release, and achieving a stable release speed over a long period of time is provided. A controlled release composition comprising (1) a physiologically active substance or salt thereof in an amount of about 14% (w/w) to about 24% (w/w) based on the total composition weight, (2) hydroxynaphthoic acid selected from the group consisting of 3-hydroxy-2-naphthoic acid and 1-hydroxy-2-naphthoic acid or salt thereof, and (3) a lactic acid polymer or salt thereof having a weight-average molecular weight of 15000 to 50000 in which the content of polymers having molecular weights of 5000 or less is about 5% by weight or less, wherein the molar ratio of said hydroxynaphthoic acid or salt thereof to said physiologically active substance or salt thereof is from 3:4 to 4:3.Type: GrantFiled: July 29, 2008Date of Patent: November 29, 2011Assignee: Takeda Pharmaceutical Company LimitedInventors: Kazumichi Yamamoto, Akiko Yamada, Yoshio Hata
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Publication number: 20110166084Abstract: A controlled release composition containing a physiologically active substance in high content, suppressing the initial excess release, and achieving a stable release speed over a long period of time is provided. A controlled release composition comprising (1) a physiologically active substance or salt thereof in an amount of about 14% (w/w) to about 24% (w/w) based on the total composition weight, (2) hydroxynaphthoic acid selected from the group consisting of 3-hydroxy-2-naphthoic acid and 1-hydroxy-2-naphthoic acid or salt thereof, and (3) a lactic acid polymer or salt thereof having a weight-average molecular weight of 15000 to 50000 in which the content of polymers having molecular weights of 5000 or less is about 5% by weight or less, wherein the molar ratio of said hydroxynaphthoic acid or salt thereof to said physiologically active substance or salt thereof is from 3:4 to 4:3.Type: ApplicationFiled: March 16, 2011Publication date: July 7, 2011Inventors: Kazumichi Yamamoto, Akiko Yamada, Yoshio Hata
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Publication number: 20110014299Abstract: The present invention provides a solid preparation containing compound (I) [compound (I) is as defined in the specification] or a salt thereof, and metformin hydrochloride, which is useful as a therapeutic drug for diabetes and the like, and superior in the preservation stability. A solid preparation having a first part and a second part: a first part: a part containing compound (I) or a salt thereof and substantially free of metformin hydrochloride a second part: a part containing metformin hydrochloride and substantially free of compound (I) and a salt thereof.Type: ApplicationFiled: July 16, 2008Publication date: January 20, 2011Applicant: Takeda Pharmaceutical Company LimitedInventors: Kazumichi Yamamoto, Hiroyoshi Koyama
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Publication number: 20100136127Abstract: The present invention provides a solid preparation containing compound (I) [compound (I) is as defined in the specification] or a salt thereof, and metformin hydrochloride, which is useful as a therapeutic drug for diabetes and the like, and superior in the preservation stability. A solid preparation having a first part and a second part: a first part: a part containing compound (I) or a salt thereof and substantially free of metformin hydrochloride a second part: a part containing metformin hydrochloride and substantially free of compound (I) and a salt thereof.Type: ApplicationFiled: July 16, 2008Publication date: June 3, 2010Inventors: Kazumichi Yamamoto, Hiroyoshi Koyama
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Patent number: 7480445Abstract: Within a television broadcast recording/reproducing apparatus, for preventing a commercial message (CM) from being cut when viewing an abridgement (digest), and for presenting the CM to a viewer without losing an advantage of viewing the abridgement, a ranking value of a CM portion is changed, with using a means for evaluating video and audio by one (1) frame thereof, thereby to give a ranking value thereto, and a means for detecting a CM portion.Type: GrantFiled: December 13, 2006Date of Patent: January 20, 2009Assignee: Hitachi, Ltd.Inventors: Kazumichi Yamamoto, Yukio Fujii
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Publication number: 20090005318Abstract: A controlled release composition containing a physiologically active substance in high content, suppressing the initial excess release, and achieving a stable release speed over a long period of time is provided. A controlled release composition comprising (1) a physiologically active substance or salt thereof in an amount of about 14% (w/w) to about 24% (w/w) based on the total composition weight, (2) hydroxynaphthoic acid selected from the group consisting of 3-hydroxy-2-naphthoic acid and 1-hydroxy-2-naphthoic acid or salt thereof, and (3) a lactic acid polymer or salt thereof having a weight-average molecular weight of 15000 to 50000 in which the content of polymers having molecular weights of 5000 or less is about 5% by weight or less, wherein the molar ratio of said hydroxynaphthoic acid or salt thereof to said physiologically active substance or salt thereof is from 3:4 to 4:3.Type: ApplicationFiled: July 29, 2008Publication date: January 1, 2009Inventors: Kazumichi Yamamoto, Akiko Yamada, Yoshio Hata
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Patent number: 7429559Abstract: A controlled release composition containing a physiologically active substance in high content, suppressing the initial excess release, and achieving a stable release speed over a long period of time is provided. A controlled release composition comprising (1) a physiologically active substance or salt thereof in an amount of about 14% (w/w) to about 24% (w/w) based on the total composition weight, (2) hydroxynaphthoic acid selected from the group consisting of 3-hydroxy-2-naphthoic acid and 1-hydroxy-2-naphthoic acid or salt thereof, and (3) a lactic acid polymer or salt thereof having a weight-average molecular weight of 15000 to 50000 in which the content of polymers having molecular weights of 5000 or less is about 5% by weight or less, wherein the molar ratio of said hydroxynaphthoic acid or salt thereof to said physiologically active substance or salt thereof is from 3:4 to 4:3.Type: GrantFiled: June 28, 2002Date of Patent: September 30, 2008Assignee: Takeda Pharmaceutical Company LimitedInventors: Kazumichi Yamamoto, Akiko Yamada, Yoshio Hata
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Patent number: 7388032Abstract: A sustained-release composition containing a hydroxynaphthoic acid salt of a biologically active substance and a biodegradable polymer, a method of its production, and a pharmaceutical composition containing said sustained-release composition.Type: GrantFiled: March 12, 2004Date of Patent: June 17, 2008Assignee: Takeda Pharmaceutical Company LimitedInventors: Akira Saikawa, Yasutaka Igari, Yoshio Hata, Kazumichi Yamamoto
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Publication number: 20080014237Abstract: Sustained release compositions containing a physiologically active substance or its salt, hydroxynaphthoic acid or its salt and a lactic acid-glycolic polymer or its salt, wherein the product of the weight-average molecular weight of the lactic acid-glycolic acid polymer by the amount (?mol) of the terminal carboxyl group per unit mass (g) of the lactic acid-glycolic acid polymer is from 1,200,000 to 3,000,000 (inclusive); and their production; medicaments containing these sustained release compositions, etc.Type: ApplicationFiled: July 25, 2007Publication date: January 17, 2008Inventors: Yasutaka Igari, Yoshio Hata, Kazumichi Yamamoto
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Patent number: 7265157Abstract: Sustained release compositions containing a physiologically active substance or its salt, hydroxynaphthoic acid or its salt and a lactic acid-glycolic polymer or its salt, wherein the product of the weight-average molecular weight of the lactic acid-glycolic acid polymer by the amount (?mol) of the terminal carboxyl group per unit mass (g) of the lactic acid-glycolic acid polymer is from 1,200,000 to 3,000,000 (inclusive); and their production; medicaments containing these sustained release compositions, etc.Type: GrantFiled: July 13, 2000Date of Patent: September 4, 2007Assignee: Takeda Pharmaceutical Company LimitedInventors: Yasutaka Igari, Yoshio Hata, Kazumichi Yamamoto
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Publication number: 20070154178Abstract: Within a television broadcast recording/reproducing apparatus, for preventing a commercial message (CM) from being cut when viewing an abridgement (digest), and for presenting the CM to a viewer without losing an advantage of viewing the abridgement, a ranking value of a CM portion is changed, with using a means for evaluating video and audio by one (1) frame thereof, thereby to give a ranking value thereto, and a means for detecting a CM portion.Type: ApplicationFiled: December 13, 2006Publication date: July 5, 2007Inventors: Kazumichi Yamamoto, Yokio Fujii
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Publication number: 20060177506Abstract: A controlled release composition for oral administration, which comprises a physiologically active substance which is a compound represented by the formula: wherein n is an integer of 1 to 3, and Ar is an aromatic ring which may be substituted, or a salt thereof, and a hydrophilic polymer, or a controlled release composition for oral administration, wherein a core containing the physiologically active substance is coated with a coating layer containing a polymer, is provided.Type: ApplicationFiled: March 16, 2004Publication date: August 10, 2006Inventors: Shigeo Yanai, Kazumichi Yamamoto
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Publication number: 20050214330Abstract: A process for producing a sustained-release composition which comprises mixing an aqueous solution containing a physiologically active substance and an acid or base in a molar amount of 1.5 or more times that of the physiologically active substance with a solution of a biodegradable polymer and then drying the mixture is provided.Type: ApplicationFiled: June 24, 2003Publication date: September 29, 2005Inventors: Kazumichi Yamamoto, Kazuhiro Saito, Tetsuo Hoshino