Abstract: An object of the present invention is to provide a novel integrase inhibitor. The present invention relates to a novel compound having an antiviral effect, more specifically, a pyridone derivative having HIV integrase inhibitory activity, and a medicament containing the same, in particular, an anti-HIV agent. The compound of the present invention has integrase inhibitory activity and/or cell proliferation inhibitory activity against viruses, in particular, HIV and drug-resistant strains thereof. Thus, the compound is useful in preventing or treating various diseases, viral infections (for example, AIDS), and the like in which integrase participates.

Abstract: A method for fusion splicing of a holey optical fiber with a cladding having a large number of air holes along the axis thereof to another optical fiber includes the use of arc discharge heating. First, the method uses arc discharge heating such that the temperature of a position rearward of an end surface of the holey optical fiber is higher than the temperature of the end surface, thereby making a tip portion of the holey optical fiber transparent. Next, the cores are aligned with one another. Then the method includes performing fusion splicing by second arc discharge heating. The first arc discharge heating is performed between discharge electrodes positioned rearward of the end surface of the holey optical fiber. The arc heating time of the first arc discharge heating is preferably 200 to 400 milliseconds.

Abstract: A method for fusion splicing of a holey optical fiber with a cladding having a large number of air holes along the axis thereof to another optical fiber includes the use of arc discharge heating. First, the method uses arc discharge heating such that the temperature of a position rearward of an end surface of the holey optical fiber is higher than the temperature of the end surface, thereby making a tip portion of the holey optical fiber transparent. Next, the cores are aligned with one another. Then the method includes performing fusion splicing by second arc discharge heating. The first arc discharge heating is performed between discharge electrodes positioned rearward of the end surface of the holey optical fiber. The arc heating time of the first arc discharge heating is preferably 200 to 400 milliseconds.

Abstract: An object of the present invention is to provide a novel integrase inhibitor. The present invention relates to a novel compound having an antiviral effect, more specifically, a pyridone derivative having HIV integrase inhibitory activity, and a medicament containing the same, in particular, an anti-HIV agent. The compound of the present invention has integrase inhibitory activity and/or cell proliferation inhibitory activity against viruses, in particular, HIV and drug-resistant strains thereof. Thus, the compound is useful in preventing or treating various diseases, viral infections (for example, AIDS), and the like in which integrase participates.

Abstract: A method of determining a heating amount adequate for fusion splicing is provided. In the method, the melting state of the end portions of optical fibers can be monitored on a real time basis so that fewer tests need to be performed. A method of fusion splicing and a fusion splicer are also provided. In the method of determining the heating amount, end portions of optical fibers that are placed opposite one another with a predetermined gap therebetween are heat-melted; an image of portions to be heat-melted is observed with an image-capturing device; and a luminance, a light emitting width, or a change in the luminance or the light emitting width is measured. In the method of fusion splicing, optical fibers are heat-melted with the heating amount that is determined using test fibers in advance, or determined using the optical fibers to be fusion spliced.

Abstract: An optical fiber reinforcement processing apparatus and reinforcement processing method are provided where it is not necessary to dispose a temperature detecting device such as a thermistor, and a heating control in which the detected temperature is not varied, the power consumption is low, and which is accurate is enabled. An optical fiber reinforcement processing apparatus in which a fusion-spliced portion of an optical fiber is covered by a heat-shrinkable reinforcing sleeve to perform reinforcement has: heating controlling means for performing a heating control on a heater which heats the reinforcing sleeve; and temperature detecting means for detecting a heating temperature of the heater on the basis of a change of the resistance of the heater. The heating control and the temperature detection are performed by controlling time periods of turning on/off a power supply to the heater.

Abstract: A fusion splicer that can execute fusion splice and reinforcement preparations of optical fibers to be next subjected to reinforcement treatment efficiently at a proper timing by keeping track of the reinforcement treatment progress state to perform fusion splice and reinforcement treatment in parallel with each other is provided. A fusion splicer includes a fusion splicing device for butting optical fiber end parts against each other and fusing them and a reinforcement treatment device for reinforcing the optical fibers subjected to the fusion splice with a reinforcement sleeve covered thereon, and a display for monitoring the state of fusion splice comprises a display function of displaying the progress state of reinforcement treatment. The reinforcement treatment progress state is displayed as temperature rise, heat insulation, cooling information or is displayed as time information or temperature information.

Abstract: An optical fiber reinforcement processing apparatus and reinforcement processing method are provided where it is not necessary to dispose a temperature detecting device such as a thermistor, and a heating control in which the detected temperature is not varied, the power consumption is low, and which is accurate is enabled. An optical fiber reinforcement processing apparatus in which a fusion-spliced portion of an optical fiber is covered by a heat-shrinkable reinforcing sleeve to perform reinforcement has: heating controlling means for performing a heating control on a heater which heats the reinforcing sleeve; and temperature detecting means for detecting a heating temperature of the heater on the basis of a change of the resistance of the heater. The heating control and the temperature detection are performed by controlling time periods of turning on/off a power supply to the heater.

Abstract: The optical fiber fusion-splice device comprises a pair of electric discharge electrodes provided opposed to each other along a predetermined axis, a conductor electrode disposed on one side with respect to a plane with the predetermined axis contained therein, and section for generating electrostatic attraction in the direction tending from the above-described plane toward the one side, between the conductor electrode and the electric discharge path produced between the electric discharge electrodes. The means for generating electrostatic attraction is connected to the conductor electrode. This fusion splicer fusion-splices together the end portions of optical fibers disposed on the other side with respect to the above plane by electric discharge produced between the electric discharge electrodes.

Abstract: A method and apparatus capable of fusion splicing optical fibers to have a low loss or a prescribed loss. The method includes (a) detecting fiber positions and core positions of optical fibers to be spliced at an abutting position and a fiber offset that is caused when said optical fibers are in core alignment (b) determining the self-alignment ratio corresponding to the preferred melted condition value based on a predetermined expression for a relationship between melted condition value and self-alignment ratio, (c1) determining an intentional offset that achieves a prescribed splicing loss based on the fiber offset and the self-alignment ratio, (d1) aligning the core positions by offsetting the intentional offset value, and (e1) heating and fusing the optical fibers.

Abstract: An object of the invention is to provide an optical fiber coating removing apparatus which can remove coating from an optical fiber preform without damaging the optical fiber surface. The apparatus is excellent in workability because positioning or the like for coating removal easily. The invention provides an optical fiber coating removing apparatus for holding coating 1b of an end portion of an optical fiber 1 between a pair of coating removing blades and removing the coating 1b from the optical fiber 1 with the pair of the blades. In each blade 11, 11?, a blade pressing plate 12, 12?, a semicircular blade 13, 13? having a semicircular eating blade portion 13a, and a flat blade 14, 14? having a straight-line eating blade portion 14a having a triangular section are integrally laminated onto a blade bearing plate 15, 15? in that order. The coating 1b is removed without damaging the surface of the optical fiber.

Abstract: A method of determining a heating amount adequate for fusion splicing is provided. In the method, the melting state of the end portions of optical fibers can be monitored on a real time basis so that fewer tests need to be performed. A method of fusion splicing and a fusion splicer are also provided. In the method of determining the heating amount, end portions of optical fibers that are placed opposite one another with a predetermined gap therebetween are heat-melted; an image of portions to be heat-melted is observed with an image-capturing device; and a luminance, a light emitting width, or a change in the luminance or the light emitting width is measured. In the method of fusion splicing, optical fibers are heat-melted with the heating amount that is determined using test fibers in advance, or determined using the optical fibers to be fusion spliced.

Abstract: A method and apparatus capable of fusion splicing optical fibers to have a low loss or a prescribed loss. The method includes (a) detecting fiber positions and core positions of optical fibers to be spliced at an abutting position and a fiber offset that is caused when said optical fibers are in core alignment (b) determining the self-alignment ratio corresponding to the preferred melted condition value based on a predetermined expression for a relationship between melted condition value and self-alignment ratio, (c1) determining an intentional offset that achieves a prescribed splicing loss based on the fiber offset and the self-alignment ratio, (d1) aligning the core positions by offsetting the intentional offset value, and (e1) heating and fusing the optical fibers.

Abstract: A method for handling a fusion-spliced optical fiber and a transferring jig for transporting the optical fiber are provided. The jig is capable of holding the fusion-spliced optical fiber in a state in which a given tension is applied at the spliced portion, and stopping the application of such tension if needed. The jig is easy to transport and set to each of separate processing processes. In the method, a fusion-spliced optical fiber is clamped at coated portions thereof on both sides of the fusion-spliced portion by a pair of clamps of the jig and transported by the jig holding the optical fiber in a state wherein a given tension is applied thereto through the clamps.

Abstract: A fusion splicing apparatus for fusion splicing end portions of optical fiber by butt discharging. Parameter data of a brightness distribution waveform of optical fiber in cross section is measured from a picked up image. A degree of attribution for the measured parameter data is obtained from fuzzy operation data registered in advance, and the type of the optical fiber is identified through a fuzzy operation. The identified type of the optical fiber is collated with fusion splicing conditions for type of optical fibers registered in advance. The collation result is displayed.

Abstract: The optical fiber fusion-splice device comprises a pair of electric discharge electrodes provided opposed to each other along a predetermined axis, a conductor electrode disposed on one side with respect to a plane with the predetermined axis contained therein, and section for generating electrostatic attraction in the direction tending from the above-described plane toward the one side, between the conductor electrode and the electric discharge path produced between the electric discharge electrodes. The means for generating electrostatic attraction is connected to the conductor electrode. This fusion splicer fusion-splices together the end portions of optical fibers disposed on the other side with respect to the above plane by electric discharge produced between the electric discharge electrodes.

Abstract: An object of the invention is to provide an optical fiber coating removing apparatus which can remove coating from an optical fiber preform without damaging the optical fiber surface. The apparatus is excellent in workability because positioning or the like for coating removal easily. The invention provides an optical fiber coating removing apparatus for holding coating 1b of an end portion of an optical fiber 1 between-a pair of coating removing blades and removing the coating 1b from the optical fiber 1 with the pair of the blades. In each blade 11, 11?, a blade pressing plate 12, 12?, a semicircular blade 13, 13? having a semicircular eating blade portion 13a, and a flat blade 14, 14? having a straight-line eating blade portion 14a having a triangular section are integrally laminated onto a blade bearing plate 15, 15? in that order. The coating 1b is removed without damaging the surface of the optical fiber.

Abstract: It is an object of the invention to provide an apparatus and method for fusion splicing the optical fibers under the fusion splicing conditions suitable for respective optical fibers in which the types of optical fibers can be fully discriminated.