Patents by Inventor Kazunori Aoki

Kazunori Aoki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100245389
    Abstract: There is provided a technique for smoothly performing position (movement) adjustment of a waveform marker by making switching between rough adjustment and fine adjustment in a series of marker operations possible with a single means and continuously. A display control section displays a measured waveform on the two-dimensional coordinates, which have a first axis and a second axis perpendicular to the first axis, on the display section. A waveform marker is movable by a marker operation corresponding to a direction parallel to the first axis. The display control section has a detecting section, which detects the marker operation corresponding to a direction parallel to the second axis, and changes either setting of the waveform marker or the display range of the measured waveform according to the detection result of the detecting section.
    Type: Application
    Filed: March 31, 2010
    Publication date: September 30, 2010
    Inventor: Kazunori Aoki
  • Publication number: 20100189001
    Abstract: A signal analyzer for facilitating observation of a relative value, i.e., the quantity of variation in power between slots, at the time of analyzing the power of a signal which is to be measured and subjected to power control in units of slot. An analyzing section detects the power value of every slot of a signal which is to be measured and received at a receiving section, and calculates the relative value of the power value between each slot and a slot separated therefrom by a predetermined number. A display control section displays the relative values thus calculated as a graph at a display section by arranging them continuously in time series.
    Type: Application
    Filed: July 1, 2008
    Publication date: July 29, 2010
    Applicant: ANRITSU CORPORATION
    Inventors: Kazunori Aoki, Naofumi Naruse
  • Publication number: 20100130291
    Abstract: A spline shaft that can suppress occurrence of stick slip by measures other than just simply making the surface roughness smaller. The spline shaft includes a first shaft with an outer-peripheral spline formed, and a second shaft with an inner-peripheral spline, which engages with the outer-peripheral spline peripherally and that is made slidable axially, formed. And, at least either one of the outer-peripheral spline and the inner-peripheral spline includes a substrate whose surface is formed to a predetermined surface roughness, and an amorphous carbon-system hard thin film, which coats and forms the surface of substrate.
    Type: Application
    Filed: October 6, 2006
    Publication date: May 27, 2010
    Applicant: JTEKT Corporation
    Inventors: Junji Ando, Yoshiaki Senga, Tomoo Suzuki, Kazunori Aoki, Toshiyuki Saito, Hirofumi Kuwabara
  • Publication number: 20100108162
    Abstract: A pipe coupling member for high-pressure fluid such as liquefied hydrogen includes a seal ring having a highly effective sealing function to prevent leakage of the fluid. The seal ring (72) is set in a seal ring setting space (39) defined by a second radial surface (36) and a seal ring setting surface (38) of a first tubular member (20), a forward end surface of a second tubular member (22), and the outer peripheral surface of a valve seat member (24). A forward end portion of the second tubular member (22) is provided with a communication hole (84) radially penetrating the forward end portion. The pressure of the high-pressure fluid on the downstream side of a valve seat surface (52) causes a fluid path in the second tubular member to be communicated with the sealing ring setting space (39) via the communication hole (84) and via a gap between the seal ring setting surface (38) and the outer peripheral surface of the forward end portion of the second tubular member.
    Type: Application
    Filed: March 19, 2008
    Publication date: May 6, 2010
    Inventors: Takuya Nishio, Kunihiko Goto, Kazunori Aoki, Osamu Yamamoto, Kazuyoshi Tashiro, Goro Suzuki, Shinichi Nomura, Kosei Yoshida
  • Publication number: 20090175825
    Abstract: An antiproliferative effect of IFN-? gene transduction in pancreatic cancer cells. The invention relates to expression of IFN-? to effectively induce growth suppression and cell death in pancreatic cancer cells, an effect which appeared to be more prominent when compared with other types of cancers and normal cells. Another aspect of the invention relates to targeting the characteristic genetic aberration, K-ras point mutation, in pancreatic cancer, and that the expression of antisense K-ras RNA significantly suppresses the growth of pancreatic cancer cells. When these two gene therapy strategies are combined, the expression of antisense K-ras RNA significantly enhanced IFN-?-induced cell death (1.3-3.5 fold), and suppressed subcutaneous growth of pancreatic cancer cells in mice. The invention also relates to a method of suppressing pancreatic cancer cells using double strand RNA formed by antisense and endogeneous K-ras RNA in combination with the anti-tumor activity of IFN-?.
    Type: Application
    Filed: February 20, 2009
    Publication date: July 9, 2009
    Applicant: Japan Health Sciences Foundation,
    Inventors: Kazunori AOKI, Teruhiko Yoshida
  • Patent number: 7514416
    Abstract: Methods of suppressing growth of pancreatic tumors or cancer cells having a K-ras gene point mutation in a mammal, comprising: administering therapeutically effective amounts of adenoviral vector and antisense K-ras expressing vector to pancreatic cancer cells via intratumoral administration, wherein the adenoviral vector comprises a DNA sequence encoding a human IFN-alpha and operably linked to a promoter, and the pancreatic cancer cells to which the adenoviral vector is administered express the human IFN-alpha; and the antisense K-ras expressing vector comprises an antisense K-ras nucleotide sequence, wherein the antisense K-ras nucleotide sequence is operably linked to a promoter, and the pancreatic cancer cells to which the anti-sense K-ras expressing vector is administered express the antisense K-ras nucleotide sequence; whereby expression of the human IFN-alpha and the antisense K-ras nucleotide sequence suppress growth of pancreatic tumor or cancer cells in the mammal.
    Type: Grant
    Filed: April 26, 2005
    Date of Patent: April 7, 2009
    Assignee: Japan Health Sciences Foundation
    Inventors: Kazunori Aoki, Teruhiko Yoshida
  • Publication number: 20090074727
    Abstract: The present invention provides a method of immune/gene combination therapy that has an effect of suppressing growth of an intractable solid tumor and is useful for treatment of such a tumor, and a therapeutic composition used for said method.
    Type: Application
    Filed: September 19, 2007
    Publication date: March 19, 2009
    Applicant: NATIONAL CANCER CENTER
    Inventors: Kazunori AOKI, Teruhiko YOSHIDA
  • Publication number: 20050260167
    Abstract: An antiproliferative effect of IFN-? gene transduction in pancreatic cancer cells. The invention relates to expression of IFN-? to effectively induce growth suppression and cell death in pancreatic cancer cells, an effect which appeared to be more prominent when compared with other types of cancers and normal cells. Another aspect of the invention relates to targeting the characteristic genetic aberration, K-ras point mutation, in pancreatic cancer, and that the expression of antisense K-ras RNA significantly suppresses the growth of pancreatic cancer cells. When these two gene therapy strategies are combined, the expression of antisense K-ras RNA significantly enhanced IFN-?-induced cell death (1.3-3.5 fold), and suppressed subcutaneous growth of pancreatic cancer cells in mice. The invention also relates to a method of suppressing pancreatic cancer cells using double strand RNA formed by antisense and endogeneous K-ras RNA in combination with the anti-tumor activity of IFN-?.
    Type: Application
    Filed: April 26, 2005
    Publication date: November 24, 2005
    Applicant: JAPAN HEALTH SCIENCES FOUNDATION
    Inventors: Kazunori Aoki, Teruhiko Yoshida
  • Patent number: 6227719
    Abstract: A plastic optical fiber connector in which at least a pair of plug connectors having plastic optical fiber cables are held so that the end faces of optical fibers are opposed to each other, includes an adaptor which is provided with a plurality of connector receptacles that receive the plug connectors inserted therein from opposite directions.
    Type: Grant
    Filed: April 23, 1998
    Date of Patent: May 8, 2001
    Assignee: Kyocera Elco Corporation
    Inventors: Kazunori Aoki, Hiroyuki Oyama
  • Patent number: 6059461
    Abstract: An optical fiber connector assembly includes a connector housing having a plug-receiving cavity. A plug connector is provided for terminating an optical fiber and includes a forward mating end for surrounding a core of the fiber. The plug connector includes a rearward engaging portion for selective interengagement with a second plug connector in parallel with the first plug connector. The forward mating end is insertable into the plug-receiving cavity of the connector housing while the rearward engaging portion is exposed exteriorly of the cavity when the mating end is fully inserted into the cavity. Therefore, the plug connector can be used individually with the connector housing or interengaged with the second plug connector.
    Type: Grant
    Filed: November 7, 1997
    Date of Patent: May 9, 2000
    Assignee: Molex Corporation
    Inventors: Kazunori Aoki, Tatsuo Inoue, Shinsuke Kunishi
  • Patent number: 5444809
    Abstract: A flame retardant resin composition comprising a mixture of:a) 10 to 70 parts by weight of an ethylene/(meth)acrylic ester copolymer;b) 30 to 90 parts by weight of a low crystalline ethylene/higher olefin copolymer;c) 0 to 30 parts by weight of an ethylene polymer selected from the group consisting of polyethylene and crystalline ethylene/.alpha.-olefin copolymers;d) 150 to 250 parts by weight, based on 100 parts by weight of the polymer components a), b) and c), of a metal hydroxide flame retardant; ande) 2 to 30 parts by weight of red phosphorus, anda flame retardant plastic optical fiber cable comprising a plastic optical fiber core and the above resin composition covering the plastic optical fiber core.
    Type: Grant
    Filed: September 6, 1994
    Date of Patent: August 22, 1995
    Assignees: Mitsubhishi Rayon Company Ltd., Du Pont-Mitsui Polychemicals Co., Ltd.
    Inventors: Kazunori Aoki, Yasufumi Yamamoto, Koji Ueki
  • Patent number: 5140868
    Abstract: A viscous and rubber-type torsional damper including a boss portion, a pulley portion, and connecting members for elastically connecting the boss portion and the pulley portion. The connecting portions are spaced from each other in an axial direction of the torsional damper and define a fluid-tight closed space therebetween. At least one protrusion is formed on at least one of the boss portion and the pulley portion. The protrusion protrudes into the closed space and a gap is formed between the surfaces of the protrusion and the surfaces opposing the protrusion. The area between the surfaces is filled with a viscous fluid such as a silicone oil. Due to this structure, the viscous damping ability of the damper is increased without increasing the radial size of the damper and without increasing the number of constructing members of the damper.
    Type: Grant
    Filed: July 27, 1990
    Date of Patent: August 25, 1992
    Assignees: Toyota Jidosha Kabushiki Kaisha, Toyoda Koki Kabushiki Kaisha
    Inventors: Naohiko Mizuno, Tamio Nakakubo, Akira Oguri, Kazunori Aoki, Masayoshi Kadowaki
  • Patent number: 5136683
    Abstract: The flame-retardant cable of this invention is a single-core or multiple-core cable comprising a plastic optical fiber and at least one covering material covering this plastic optical fiber, and this flame-retardant cable is characterized in that at least one covering material is a highly flame-retardant resin, for example, a highly flame-retardant resin having an oxygen index (OI) of at least 32, preferably from 40 to 45, such as chlorinated polyethylene. This flame-retardant cable has an excellent flame retardancy with no lowering of the performances of the optical fiber. Moreover, the cable has an excellent flame resistance.
    Type: Grant
    Filed: September 10, 1990
    Date of Patent: August 4, 1992
    Assignee: Mitsubishi Rayon Company, Ltd.
    Inventors: Kazunori Aoki, Takara Yamamoto, Eiji Maeda