Patents by Inventor Kazunori Koide

Kazunori Koide has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of FR901464 and analogs with antitumor activity
    Patent number: 7825267
    Abstract: The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.
    Type: Grant
    Filed: September 8, 2007
    Date of Patent: November 2, 2010
    Assignee: University of Pittsburgh-of the Commonwealth System of Higher Education
    Inventors: Kazunori Koide, Brian J. Albert, Ananthapadmanabhan Sivaramakrishnan
  • Fluorescent ozone sensor
    Publication number: 20100255525
    Abstract: A selective, fluorescent “turn-on” probe and method for the detection of ozone in biological and atmospheric samples, wherein the method of detecting ozone in a sample comprises the steps of (1) contacting the sample with a fluorophore capable of undergoing allylic ether or allylic ester cleavage and (2) detecting fluorescence in the sample.
    Type: Application
    Filed: March 9, 2010
    Publication date: October 7, 2010
    Inventors: Kazunori Koide, Amanda L. Garner
  • Hydroxymethyl fluorescein derivatives for use as biological markers and dyes
    Publication number: 20080275257
    Abstract: Hydroxymethyl fluorescein derivatives are provided. The derivatives can be easily conjugated to other molecules, and are more permeable than other fluorescein derivatives. Methods of making the derivatives are also provided.
    Type: Application
    Filed: January 28, 2008
    Publication date: November 6, 2008
    Inventors: Kazunori Koide, Amanda L. Garner, Fengling Song
  • Detection of platinum group metals with fluorophores via allylic oxidative insertion
    Publication number: 20080274492
    Abstract: A method of detecting platinum group metals in a sample is provided. The method comprises the step of contacting the sample with a fluorophore capable of undergoing allylic ether or allylic ester cleavage. The fluorophore has an oxygen-protected moiety, the protecting group having an allylic functionality. A reducing agent and optionally a solubilizer are also added to the sample. Very low levels of platinum group metals such as palladium and platinum can be detected in a sample.
    Type: Application
    Filed: January 28, 2008
    Publication date: November 6, 2008
    Inventors: Kazunori Koide, Amanda L. Garner, Fengling Song
  • SYNTHESIS OF FR901464 AND ANALOGS WITH ANTITUMOR ACTIVITY
    Publication number: 20080096879
    Abstract: The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.
    Type: Application
    Filed: September 8, 2007
    Publication date: April 24, 2008
    Inventors: Kazunori KOIDE, Brian Albert, Ananthapadmanabhan Sivaramakrishnan
  • Molding method and molding apparatus
    Publication number: 20080016933
    Abstract: The present invention relates to a molding method of reducing a diameter in an end portion of a metal tube to be characterized in having a step of rotating a metal tube around an axial core or rotating a frame in which a plurality of ring-shaped tools are arranged, and moving the axial core of the ring-shaped tool away from the axial core of the metal tube while moving the metal tube or the frame, thereby reducing the diameter in an end portion of the metal tube.
    Type: Application
    Filed: April 25, 2007
    Publication date: January 24, 2008
    Applicant: Kabushiki Kaisha Yutaka Giken
    Inventors: Katsumi Okamoto, Kazunori Koide