Patents by Inventor Kazunori Maebashi
Kazunori Maebashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9115079Abstract: An objective of the present invention is to provide a novel NDM (New Delhi metallo-?-lactamase) inhibitor that functions as a drug for restoring the antibacterial activity of ?-lactam antibiotics that have been inactivated as a result of decomposition by NDM.Type: GrantFiled: July 26, 2012Date of Patent: August 25, 2015Assignee: MEIJI SEIKA PHARMA CO., LTD.Inventors: Akihiro Morinaka, Kazunori Maebashi, Takashi Ida, Muneo Hikida, Mototsugu Yamada, Takao Abe
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Publication number: 20140221330Abstract: An objective of the present invention is to provide a novel NDM (New Delhi metallo-?-lactamase) inhibitor that functions as a drug for restoring the antibacterial activity of ?-lactam antibiotics that have been inactivated as a result of decomposition by NDM.Type: ApplicationFiled: July 26, 2012Publication date: August 7, 2014Inventors: Akihiro Morinaka, Kazunori Maebashi, Takashi Ida, Muneo Hikida, Mototsugu Yamada, Takao Abe
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Publication number: 20070161581Abstract: Disclosed are compounds represented by general formula (I) or pharmacologically acceptable salts or solvates thereof having excellent antimicrobial activity against bacteria causative of severe infections such as pneumonia and septicemia, particularly against MRSA, and also antimicrobial agents comprising these compounds, and pharmaceutical compositions comprising these compounds as an active component.Type: ApplicationFiled: January 21, 2005Publication date: July 12, 2007Inventors: Nobuto Minowa, Takayuki Usui, Yoshihisa Akiyama, Hirawa Yukiko, Toshio Yoneta, Toshifumi Hasegawa, Kazunori Maebashi, Takashi Ida, Kazuko Katsumata, Keiko Otsuka, Daishiro Ikeda
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Patent number: 6528500Abstract: Described is an azole derivative represented by the following formula (1): wherein, R1 represents a substituted phenyl group, R2 and R3 each represents a fluorine atom, an alkyl group or the like, and R4 represents an alkyl group, or salt thereof; and a medicament comprising the derivative or salt as an effective ingredient. The compound according to the present invention exhibits excellent antimycotic action and has good aqueous solubility.Type: GrantFiled: September 28, 2000Date of Patent: March 4, 2003Assignee: SSP Co., Ltd.Inventors: Minoru Tokizawa, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato
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Patent number: 6204415Abstract: Described is a triazole derivative represented by the formula (1): wherein R1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X1 and X2 are the same or different and each independently represents a hydrogen atom, a halogen atom or a halogenoalkyl and n stands for an integer of 0 to 2, or salt thereof; a preparation process of said compound and a pharmaceutical comprising said compound as an effective ingredient. The compound as described above has high antimycotic activity and is useful for the prevention and treatment of mammalian mycotic infections.Type: GrantFiled: April 18, 2000Date of Patent: March 20, 2001Assignee: SSP Co., Ltd.Inventors: Sunao Takeda, Yasushi Kaneko, Minoru Tokizawa, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato
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Patent number: 6194592Abstract: Described is a triazole derivative represented by the formula (1): wherein R1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X1 and X2 are the same or different and each independently represents a hydrogen atom, a halogen atom or a halogenoalkyl and n stands for an integer of 0 to 2, or salt thereof; a preparation process of said compound and a pharmaceutical comprising said compound as an effective ingredient. The compound as described above has high antimycotic activity and is useful for the prevention and treatment of mammalian mycotic infections.Type: GrantFiled: April 18, 2000Date of Patent: February 27, 2001Assignee: SSP Co., Ltd.Inventors: Sunao Takeda, Yasushi Kaneko, Minoru Tokizawa, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato
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Patent number: 6184396Abstract: Described is a triazole derivative represented by the formula (1): wherein R1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X1 and X2 are the same or different and each independently represents a hydrogen atom, a halogen atom or a halogenoalkyl and n stands for an integer of 0 to 2, or salt thereof; a preparation process of said compound and a pharmaceutical comprising said compound as an effective ingredient. The compound as described above has high antimycotic activity and is useful for the prevention and treatment of mammalian mycotic infections.Type: GrantFiled: April 18, 2000Date of Patent: February 6, 2001Assignee: SSP Co., Ltd.Inventors: Sunao Takeda, Yasushi Kaneko, Minoru Tokizawa, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato
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Patent number: 6172266Abstract: Described is a triazole derivative represented by the formula (1): wherein R1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X1 and X2 are the same or different and each independently represents a hydrogen atom, a halogen atom or a halogenoalkyl and n stands for an integer of 0 to 2, or salt thereof; a preparation process of said compound and a pharmaceutical comprising said compound as an effective ingredient. The compound as described above has high antimycotic activity and is useful for the prevention and treatment of mammalian mycotic infections.Type: GrantFiled: December 23, 1999Date of Patent: January 9, 2001Assignee: SSP Co., Ltd.Inventors: Sunao Takeda, Yasushi Kaneko, Minoru Tokizawa, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato
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Patent number: 6083968Abstract: Described is a triazole derivative represented by the formula (1): ##STR1## wherein R.sup.1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X.sup.1 and X.sup.2 are the same or different and each independently represents a hydrogen atom, a halogen atom or a halogenoalkyl and n stands for an integer of 0 to 2, or salt thereof; a preparation process of said compound and a pharmaceutical comprising said compound as an effective ingredient.The compound as described above has high antimycotic activity and is useful for the prevention and treatment of mammalian mycotic infections.Type: GrantFiled: December 9, 1998Date of Patent: July 4, 2000Assignee: SSP Co., Ltd.Inventors: Sunao Takeda, Yasushi Kaneko, Minoru Tokizawa, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato
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Patent number: 6063945Abstract: A compound having formula (2): ##STR1## wherein R represents hydrogen, a straight or branched C.sub.1-10 alkyl group, a C.sub.7-11 aralkyl group or a C.sub.2-10 carboacyl group and m stands for 1 to 5.Type: GrantFiled: June 8, 1999Date of Patent: May 16, 2000Assignee: SS Pharmaceutical Co., Ltd.Inventors: Minoru Tokizawa, Sunao Takeda, Yasushi Kaneko, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato, Hideaki Matsuda
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Patent number: 6040325Abstract: Described is a triazole derivative represented by the formula (1): wherein R.sup.1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X.sup.1 and X.sup.2 are the same or different and each independently represents a hydrogen atom, a halogen atom or a halogenoalkyl and n stands for an integer of 0 to 2, or salt thereof; a preparation process of said compound and a pharmaceutical comprising said compound as an effective ingredient.The compound as described above has high antimycotic activity and is useful for the prevention and treatment of mammalian mycotic infections.Type: GrantFiled: January 22, 1999Date of Patent: March 21, 2000Assignee: SSP Co., Ltd.Inventors: Sunao Takeda, Yasushi Kaneko, Minoru Tokizawa, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato
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Patent number: 6008239Abstract: Described is a triazole derivative represented by the formula (1): ##STR1## wherein R.sup.1 represents a lower alkyl group or an aralkyl group, R.sup.2 represents a hydrogen atom, a lower alkyl group, an aralkyl group or an acyl group, X.sup.1 and X.sup.2 are the same or different and each independently represents a hydrogen atom, a halogen atom or a trifluoromethyl group, n stands for an integer of 0 to 2 and m stands for an integer of 1 to 5, or salt thereof; and also a pharmaceutical comprising the derivative or salt thereof as an effective ingredient. The compound as described above has a high antimycotic activity and is useful for the prevention and treatment of mammalian mycotic infections.Type: GrantFiled: August 17, 1998Date of Patent: December 28, 1999Assignee: SSP Co., Ltd.Inventors: Yasushi Kaneko, Sunao Takeda, Minoru Tokizawa, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato
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Patent number: 6002028Abstract: Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1) or salt thereof. ##STR1## wherein n stands for 0, 1 or 2, X.sup.1 represents H or F and Y.sup.1 and Y.sup.2 each independently represents H, halogen or CF.sub.3.Type: GrantFiled: May 14, 1999Date of Patent: December 14, 1999Assignee: SS Pharmaceutical Co., Ltd.Inventors: Minoru Tokizawa, Sunao Takeda, Yasushi Kaneko, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato, Hideaki Matsuda
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Patent number: 5986144Abstract: Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1) or salt thereof. wherein n stands for 0, 1 or 2, X.sup.1 represents H or F and Y.sup.1 and Y.sup.2 each independently represents H, halogen or CF.sub.3.Type: GrantFiled: May 14, 1999Date of Patent: November 16, 1999Assignee: SS Pharmaceutical Co., Ltd.Inventors: Minoru Tokizawa, Sunao Takeda, Yasushi Kaneko, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato, Hideaki Matsuda
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Patent number: 5945438Abstract: Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1) or salt thereof. ##STR1## wherein n stands for 0, 1 or 2, X.sup.1 represents H or F and Y.sup.1 and Y.sup.2 each independently represents H, halogen or CF.sub.3.Type: GrantFiled: December 17, 1996Date of Patent: August 31, 1999Assignee: SS Pharmaceutical Co., Ltd.Inventors: Minoru Tokizawa, Sunao Takeda, Yasushi Kaneko, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato, Hideaki Matsuda
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Patent number: 5939448Abstract: Described is a triazole derivative represented by the formula (1): wherein R represents a hydrogen atom, an alkyl group, an aralkyl group or an acyl group, n stands for 0 to 2 and m stands for 1 to 5 or salt thereof, and a pharmaceutical containing the derivative or salt as an effective ingredient.Type: GrantFiled: June 10, 1997Date of Patent: August 17, 1999Assignee: SS Pharmaceutical Co., Ltd.Inventors: Minoru Tokizawa, Sunao Takeda, Yasushi Kaneko, Hiromichi Eto, Kazuya Ishida, Kazunori Maebashi, Masaru Matsumoto, Takemitsu Asaoka, Susumu Sato, Hideaki Matsuda
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Patent number: 5147886Abstract: A triazole derivative is disclosed. The compound have a general formula, ##STR1## wherein R.sup.1 and R.sup.2 represent a hydrogen atom or a lower alkyl group, or R.sup.1 and R.sup.2 together form a lower alkylene group, R.sup.3 represents a lower alkyl group, and n denotes an integer of 0 to 2, provided that not both R.sup.1 and R.sup.2 are a hydrogen atom at the same time. The triazole derivatives and their salts are effective for curing or preventing deep-seated mycoses, e.g. mycotic meningitis, mycotic infectious diseases of respiratory organs, fungemia, and urinary tract mycosis.Type: GrantFiled: December 12, 1990Date of Patent: September 15, 1992Assignee: SS Pharmaceutical Co., Ltd.Inventors: Minoru Tokizawa, Yoshihiko Kanamaru, Masaru Matsumoto, Takemitsu Asaoka, Hideaki Matsuda, Tadayuki Kuraishi, Kazunori Maebashi, Naokata Taido, Ryuichi Kawahara