Abstract: A syringe cylinder 12 includes a groove 32 formed in an inner peripheral surface thereof and extending over a predetermined length from an opening end 30 thereof. Even with the intermediate sliding stopper 14 located at a position where the groove 32 is formed, the pressure inside the syringe cylinder 12 can be reduced. Thus, during vacuum tapping, the intermediate sliding stopper 14 can be held in the vicinity of the opening end 30 of the syringe cylinder 12. Consequently, the intermediate sliding stopper 14 can be inserted into the syringe cylinder 12 in a correct posture and reliably moved to a predetermined position in the syringe cylinder 12.

Abstract: In a prefilled syringe separately containing both a lidocaine solution and a hyaluronic acid solution, the viscosity of the hyaluronic acid solution is set so as to be sufficiently higher than the viscosity of the lidocaine solution. When lidocaine discharge from the tip of a hypodermic needle ends, the force f (N) required to discharge the hyaluronic acid solution from the needle tip suddenly increases, imparting sort of a jolt to the hand of the operator and creating a momentary sensation that the plunger is at rest. Letting the force f (N) required to discharge the lidocaine solution be P1 and the force f (N) required to discharge the hyaluronic acid solution be P2, the relationship therebetween is P1<P2. When (P2?P1)/P2>0.2, the operator is able to feel a sufficient jolt.

Abstract: A patch comprising a backing layer and a adhesive layer formed on the back face of the backing layer wherein a woven fabric or a nonwoven fabric made of a rayon and pulp fiber mixture is employed as the backing layer and the mixing ratio thereof is from 3:7 to 7:3. When employed in taping a finger, a wrist, an ankle, neck, an elbow, a knee or the like, the patch would not soon curl up or peel off at an overlapping part. After the patch is adhered and then stripped off, no fiber piece remains on the pressure-sensitive adhesive face of the backing layer so that the adhesive force of the patch can be sustained in the case of re-adhesion.

Abstract: Sheet-type packs which exert a skin cleaning effect while maintaining an effect of appropriately moistening the skin and are excellent in the feel in using and safety to the skin. In particular, sheet-type packs containing fruit extracts.

Abstract: A warming patch 10 comprising a support 2 and adhesive layer 1 disposed on at least one surface of this support 2, wherein the adhesive, layer 1 contains a warming material, 1-menthol and polyethylene glycol as an irritation reducing agent.

Abstract: A patch comprising a backing layer and a adhesive layer formed on the back face of the backing layer wherein a woven fabric or a nonwoven fabric made of a rayon and pulp fiber mixture is employed as the backing layer and the mixing ratio thereof is from 3:7 to 7:3. When employed in taping a finger, a wrist, an ankle, neck, an elbow, a knee or the like, the patch would not soon curl up or peel off at an overlapping part. After the patch is adhered and then stripped off, no fiber piece remains on the pressure-sensitive adhesive face of the backing layer so that the adhesive force of the patch can be sustained in the case of re-adhesion.

Abstract: A sheet-form adhesive preparation which gives a comfortable refreshing feeling in use, gives a wet feeling to the skin, and is usable a a cosmetic, medicinal, or quasi-drug preparation for the sake of skin adjustment and beauty. The preparation preferably has a quantity of heat required for water evaporation of 0.6 to 13 (cal) per unit area (cm2) when exposed for 30 minutes to an atmosphere of 25° C. and 60% Rh.

Abstract: It is intended to provide sheet-type packs which have an effect of inhibiting pigmentation, spots and freckles after sunburn as well as a skin whitening effect while moisturizing the skin and maintaining adequate skin-moistening properties. Namely, sheet-type packs wherein at least a crude drug component and N-acetyltyrosine are blended with a base.

Abstract: A patch comprising a laminate having an expansible support and an adhesive layer laminated on the support; and a release sheet, attached onto the adhesive layer, having perforations formed with a predetermined interval;

Abstract: Sheet-type packs prepared by adding a refreshing agent, a perfume and/or a sebum-controlling agent to a base comprising a water-soluble polymer, polyhydric alcohol, a crosslinking agent, water and a skin-care component. These packs exert favorable effects on the skin, high safety and an excellent effect of relaxing mind and the body while maintaining appropriate stickiness to the skin.

Abstract: A steroid-containing gel patch containing a steroid as an effective ingredient at 0.005 to 0.05% by weight, crotamiton as a stabilizer at 15% by weight or less and a surfactant in a base, where the amount of the crotamiton blended being 200 to 3000-fold the weight of the steroid blended and the amount of the surfactant blended being {fraction (1/20)} to ⅕-fold the weight of the crotamiton blended.