Patents by Inventor Kazuo Ando
Kazuo Ando has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240018103Abstract: The present invention relates to 3-hydroxyoxindole derivatives which have antagonistic activities against CRHR2, and which are useful in the treatment or prevention of disorders and diseases in which CRHR2 is involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CRHR2 is involved.Type: ApplicationFiled: September 30, 2021Publication date: January 18, 2024Applicant: RaQualia Pharma Inc.Inventors: Kazuo ANDO, Masashi OHMI, Ryohei MAGARA
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Patent number: 11802120Abstract: The present invention relates to fused cyclic urea derivatives which have antagonistic activities against CRHR1 and/or CRHR2, and which are useful in the treatment or prevention of disorders and diseases in which CRHR1 and/or CRHR2 is involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CRHR1 and/or CRHR2 is involved.Type: GrantFiled: April 9, 2019Date of Patent: October 31, 2023Assignee: RaQualia Pharma Inc.Inventors: Masashi Ohmi, Takeshi Matsushita, Kazuo Ando, Ryuichi Yamaguchi, Yutaka Fukumoto, Ryohei Magara, Tatsuya Yamagishi, Mikito Takefuji
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Publication number: 20230339934Abstract: This invention relates to pyrimidin-4(3H)-one derivatives that act as modulators of the TRPV4 receptor. The present invention also relates to processes for the preparation of novel pyrimidin-4(3H)-one derivatives and to their use in the treatment of a wide range of diseases, syndromes, and disorders, in particular for the treatment of inflammatory, pain, and urological diseases or disorders.Type: ApplicationFiled: April 30, 2021Publication date: October 26, 2023Applicant: RaQualia Pharma Inc.Inventors: Yuji SHISHIDO, Tadashi INOUE, Tatsuya YAMAGISHI, Kazuo ANDO, Yutaka FUKUMOTO, Ryohei MAGARA
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Publication number: 20230149382Abstract: The present invention relates to tetrahydroquinoline derivatives of the present invention or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the P2X7 receptor.Type: ApplicationFiled: July 22, 2022Publication date: May 18, 2023Inventors: Hirohide NOGUCHI, Yoshimasa ARANO, Kazuo ANDO, Kazuki TOYOSHIMA, Toshihiko SONE, Koki MATSUBARA
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Patent number: 11077100Abstract: The present invention relates to tetrahydroquinoline derivatives of the present invention or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the P2X7 receptor.Type: GrantFiled: March 13, 2018Date of Patent: August 3, 2021Assignees: RaQualia Pharma Inc., Asahi Kasei Pharma CorporationInventors: Hirohide Noguchi, Yoshimasa Arano, Kazuo Ando, Kazuki Toyoshima, Toshihiko Sone
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Publication number: 20210085667Abstract: The present invention relates to tetrahydroquinoline derivatives of the present invention or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the P2X7 receptor.Type: ApplicationFiled: December 4, 2020Publication date: March 25, 2021Applicants: RaQualia Pharma Inc., Asahi Kasei Pharma CorporationInventors: Hirohide NOGUCHI, Yoshimasa ARANO, Kazuo ANDO, Kazuki TOYOSHIMA, Toshihiko SONE, Koki MATSUBARA
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Publication number: 20210078975Abstract: The present invention relates to fused cyclic urea derivatives which have antagonistic activities against CRHR1 and/or CRHR2, and which are useful in the treatment or prevention of disorders and diseases in which CRHR1 and/or CRHR2 is involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CRHR1 and/or CRHR2 is involved.Type: ApplicationFiled: April 9, 2019Publication date: March 18, 2021Applicants: RaQualia Pharma Inc., National University Corporation Tokai National Higher Education and Research SystemInventors: Masashi OHMI, Takeshi MATSUSHITA, Kazuo ANDO, Ryuichi YAMAGUCHI, Yutaka FUKUMOTO, Ryohei MAGARA, Tatsuya YAMAGISHI, Mikito TAKEFUJI
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Publication number: 20200405706Abstract: The present invention relates to tetrahydroquinoline derivatives of the present invention or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the P2X7 receptor.Type: ApplicationFiled: March 13, 2018Publication date: December 31, 2020Applicants: RaQualia Pharma Inc., Asahi Kasei Pharma CorporationInventors: Hirohide NOGUCHI, Yoshimasa ARANO, Kazuo ANDO, Kazuki TOYOSHIMA, Toshihiko SONE, Koki MATSUBARA
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Publication number: 20180339993Abstract: The present invention relates to azaspiro derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPM8 receptor,Type: ApplicationFiled: July 31, 2018Publication date: November 29, 2018Applicant: RaQualia Pharma Inc.Inventors: Yuji SHISHIDO, Masashi OHMI, Kazuo ANDO
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Patent number: 10093678Abstract: The present invention relates to azaspiro derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPM8 receptor.Type: GrantFiled: March 16, 2015Date of Patent: October 9, 2018Assignee: RaQualia Pharma Inc.Inventors: Yuji Shishido, Masashi Ohmi, Kazuo Ando
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Publication number: 20170002016Abstract: The present invention relates to azaspiro derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPM8 receptor.Type: ApplicationFiled: March 16, 2015Publication date: January 5, 2017Applicant: RaQualia Pharma Inc.Inventors: Yuji SHISHIDO, Masashi OHMI, Kazuo ANDO
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Patent number: 8789721Abstract: A square can capable of securing high sealing performance even if a curvature radius of a seamed portion at a seamed corner portion is reduced, enabling a reduction in a countersink depth, reduced in size, having excellent sealing ability and storage efficiency and a method and an apparatus for double seaming the square can. A second seaming roll (55) is guided by a model cam for second seaming having a model cam surface for second seaming formed in such a shape that it is swelled from a model cam surface for first seaming outwards at a corner seamed portion (5). Accordingly, the seaming shape of the corner seamed portion (5) is formed in such a shape that the seaming width thereof at the center of the corner seamed portion is larger than the seaming width of a linear sealed portion (4) and is swelled outwards to absorb an increase in sheet thickness at the corner seamed portion.Type: GrantFiled: May 16, 2006Date of Patent: July 29, 2014Assignee: Toyo Seikan Kaisha, Ltd.Inventors: Kei Oohori, Kiyotaka Yoshida, Sunao Morishita, Kanji Kuroda, Norifumi Yasuda, Kazuo Ando, Hisashi Katoh
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Patent number: 8653063Abstract: This invention relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein X, R1, R2, R3, R4, R5, R6, R7, k, m, n, p, q, r and s are each as described herein, and compositions containing such compounds, and the use of such compounds in the treatment of a condition mediated by CB2 receptor activity.Type: GrantFiled: January 22, 2010Date of Patent: February 18, 2014Assignee: RaQualia Pharma Inc.Inventors: Kazuo Ando, Yasuhiro Iwata
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Publication number: 20120187227Abstract: A facility for sorting and separating waste plastic includes: a crusher (11) for crushing waste plastic material into waste plastic fragments; a steam-cleaning device (13) for cleaning the waste plastic fragments; a primary wet specific-gravity sorter (14) and a secondary wet specific-gravity sorter (15) for separating the waste plastic fragments into floating or sinking specific-gravity-sorted fragments with a separating liquid having specific gravity which is the median of specific gravity of materials contained in the waste plastic fragments until the specific-gravity-sorted fragments contain three or less materials; and first to third electrostatic separation devices (16A to 16C) including frictional electrification devices for frictionally electrifying the specific-gravity-sorted fragments and electrostatic sorting devices for putting the frictionally electrified specific-gravity-sorted fragments into a static electric field and altering the falling directions of the specific-gravity-sorted fragments toType: ApplicationFiled: September 24, 2010Publication date: July 26, 2012Inventors: Kazuo Ando, Tetsuya Inoue, Tsutomu Niwa, Takeshi Itoga
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Publication number: 20120094964Abstract: The present invention relates to sulfamoyl benzoic acid derivatives of formula (I) or a pharmaceutically acceptable salt thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPM8 receptor.Type: ApplicationFiled: May 6, 2010Publication date: April 19, 2012Inventors: Tadashi Inoue, Masashi Ohmi, Kiyoshi Kawamura, Kazuo Ando, Yuji Shishido
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Patent number: 8138177Abstract: This invention relates to compounds of the formula (I): or pharmaceutically acceptable salts thereof, wherein: A, B, R1, R2 and R3 are each as described herein, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by CB2 receptor binding activity such as, but not limited to, inflammatory pain, nociceptive pain, neuropathic pain, fibromyalgia, chronic low back pain, visceral pain, acute cerebral ischemia, pain, chronic pain, acute pain, post herpetic neuralgia, neuropathies, neuralgia, diabetic neuropathy, HIV-related neuropathy, nerve injury, rheumatoid arthritic pain, osteoarthritic pain, back pain, cancer pain, dental pain, fibromyalgia, neuritis, sciatica, inflammation, neurodegenerative disease, cough, broncho constriction, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), colitis, cerebrovascular ischemia, emesis such as cancer chemotherapy-induced emesis, rheumatoid arthritis, asthma, Crohn's disease, ulcerative colitis, asthmaType: GrantFiled: March 2, 2006Date of Patent: March 20, 2012Assignee: Pfizer Inc.Inventors: Kazuo Ando, Makoto Kawai, Tsutomu Masuda, Hirofumi Omura
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Publication number: 20110281840Abstract: This invention relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein X, R1, R2, R3, R4, R5, R6, R7, k, m, n, p, q, r and s are each as described herein, and compositions containing such compounds, and the use of such compounds in the treatment of a condition mediated by CB2 receptor activity.Type: ApplicationFiled: January 22, 2010Publication date: November 17, 2011Inventors: Kazuo Ando, Yasuhiro Iwata
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Patent number: 7934617Abstract: A container is provided comprising a casing, a set plate closing the lower end of the casing and a lock ring that fastens the set plate onto the casing. The casing is provided with a radial outer flange formed around an open end of the main body thereof. The radial outer flange and the outer periphery of the set plate are each provided with three stop projections and three notches. The radial outer flange is further provided with three biasing projections and the outer periphery of the set plate is further provided with three engagement rims. The members of each threesome are arranged at a regular angular interval and each threesome is arranged at different angular phase positions from those of the other threesomes. The outer periphery of the lock ring is provided with three engagement lugs that project inwardly at a regular angular interval.Type: GrantFiled: June 26, 2006Date of Patent: May 3, 2011Assignee: Honda Motor Co., Ltd.Inventors: Takahiro Minowa, Kazuo Ando, Hiroyuki Tajima
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Patent number: 7700618Abstract: This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein A, R1, R2, R3, R4, R5, m and n are each as described herein, and compositions containing such compounds, and the use of such compounds in the treatment of a condition mediated by CB2 receptor activity such as, but not limited to, inflammatory pain, nociceptive pain, neuropathic pain, fibromyalgia, chronic low back pain, visceral pain, acute cerebral ischemia, pain, chronic pain, acute pain, post herpetic neuralgia, neuropathies, neuralgia, diabetic neuropathy, HIV-related neuropathy, nerve injury, rheumatoid arthritic pain, osteoarthritic pain, back pain, cancer pain, dental pain, fibromyalgia, neuritis, sciatica, inflammation, neurodegenerative disease, cough, broncho constriction, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), colitis, cerebrovascular ischemia, emesis such as cancer chemotherapy-induced emesis, rheumatoid arthritis, asthma, Crohn's disease, ulcerative colitis, asType: GrantFiled: February 23, 2007Date of Patent: April 20, 2010Assignee: Pfizer IncInventors: Tomoki Kato, Kana Kon-I, Yohei Yuki, Kazuo Ando
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Publication number: 20090298811Abstract: This invention relates to compounds and methods for the treatment of a condition mediated by CB1 receptor activity in a mammalian subject including a human, which comprises administering to a mammal in need of such treatment a therapeutically effective amount of the compound of formula (I) or pharmaceutically acceptable salts thereof, wherein: A, B, R1, R2 and R3 are each as described herein.Type: ApplicationFiled: September 3, 2007Publication date: December 3, 2009Inventors: Kazuo Ando, Ingrid Price Buchler, Shridhar Gajanan Hedge, Makoto Kawai, Tsutomu Masuda, Hirofumi Omura