Patents by Inventor Kazuo Komiya
Kazuo Komiya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8591879Abstract: The present invention provides a novel adenovirus vector for which inflammation during the in vivo administration thereof is alleviated by inhibiting the induction of expression of an adenovirus gene by a foreign promoter inserted into the adenovirus genome, and a method for producing the vector, a cell line for use in the production of the recombinant adenovirus vector, or a gene therapy method using the recombinant adenovirus vector.Type: GrantFiled: June 3, 2011Date of Patent: November 26, 2013Assignee: Dainippon Sumitomo Pharma Co., LtdInventors: Michio Nakai, Kazuo Komiya, Masashi Murata, Naoki Tohdoh, Izumu Saito
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Patent number: 8178077Abstract: The present invention provides novel target proteins and target genes for drug discovery, and the means that enable the development of novel drugs using the same. More particularly, the present invention provides NCS proteins and genes thereof; screening methods for drug (for example, anti-central nervous disease drug); agents for regulating disease (for example, central nervous disease); production methods of a drug derivative; a complex comprising a drug and NCS protein, and a method of producing the complex; a kits comprising a drug or a salt thereof; determination methods for the onset or risk of onset of a specified disease, determination methods for susceptibility to a drug, and determination kits used for the determination methods; and the like.Type: GrantFiled: October 19, 2005Date of Patent: May 15, 2012Assignee: Reverse Proteomics Research Institute Co., Ltd.Inventors: Tadakazu Yamauchi, Hideaki Sueoka, Kouichi Tsuchiya, Katsuhisa Murayama, Ken Horiuchi, Kazuo Komiya, Morikazu Kito, Takeshi Tsutsumi, Yuko Isono, Yorimasa Suwa
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Patent number: 8153385Abstract: The present invention provides a novel target protein and a gene for drug discovery, and a means that enables development of a novel pharmaceutical agent by using the same. More particularly, the present invention provides CARP and genes thereof; screening methods for drugs (e.g., antiallergic drugs); a regulator of diseases (e.g., allergic diseases); a drug derivative production method; a complex comprising a drug and CARP, and a production method thereof; kits comprising a drug or a salt thereof; determination methods for the onset or risk of onset of a specified disease, determination methods for susceptibility to a drug, and determination kits used for said methods, and the like.Type: GrantFiled: October 18, 2005Date of Patent: April 10, 2012Assignee: Reverse Proteomics Research Institute Co., Ltd.Inventors: Tadakazu Yamauchi, Hideaki Sueoka, Kouichi Tsuchiya, Katsuhisa Murayama, Kazuo Komiya, Morikazu Kito, Takeshi Tsutsumi, Yuko Isono, Motoi Tobita, Yorimasa Suwa
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Publication number: 20120020924Abstract: The present invention provides a novel adenovirus vector for which inflammation during the in vivo administration thereof is alleviated by inhibiting the induction of expression of an adenovirus gene by a foreign promoter inserted into the adenovirus genome, and a method for producing the vector, a cell line for use in the production of the recombinant adenovirus vector, or a gene therapy method using the recombinant adenovirus vector.Type: ApplicationFiled: June 3, 2011Publication date: January 26, 2012Applicant: DAINIPPON SUMITOMO PHARMA CO., LTD.Inventors: Michio Nakai, Kazuo Komiya, Masashi Murata, Naoki Tohdoh, Izumu Saito
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Publication number: 20110269141Abstract: The problems of the present invention are to provide target proteins and target genes for bioactive substances such as drugs, and means that enable the development of novel bioactive substances using the same. The present invention provides target proteins and target genes for bioactive substances; screening methods for substances capable of regulating bioactivities; bioactivity regulators; a bioactive substance derivative production method; a complex comprising a bioactive substance and a target protein, and a method of producing the complex; and kits comprising a bioactive substance or a salt thereof; determination methods for the onset or risk of onset of a specified disease or condition, determination methods for susceptibility to a bioactive substance, and determination kits used for the determination methods, and the like.Type: ApplicationFiled: February 20, 2008Publication date: November 3, 2011Applicant: REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD.Inventors: Katsuhisa Murayama, Tadakazu Yamauchi, Kouichi Tsuchiya, Kazuo Komiya, Morikazu Kito, Yuko Isono, Noriyuki Inomata, Yorimasa Suwa, Ai Wakamatsu, Junichi Yamamoto, Takao Isogai
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Publication number: 20100136524Abstract: The present invention provides a novel target protein and a gene for drug discovery, and a means that enables development of a novel pharmaceutical agent by using the same. More particularly, the present invention provides CARP and genes thereof; screening methods for drugs (e.g., antiallergic drugs); a regulator of diseases (e.g., allergic diseases); a drug derivative production method; a complex comprising a drug and CARP, and a production method thereof; kits comprising a drug or a salt thereof; determination methods for the onset or risk of onset of a specified disease, determination methods for susceptibility to a drug, and determination kits used for said methods, and the like.Type: ApplicationFiled: October 18, 2005Publication date: June 3, 2010Applicant: Reverse Proteomics Research Institute Co., Ltd.Inventors: Tadakazu Yamauchi, Hideaki Sueoka, Kouichi Tsuchiya, Katsuhisa Murayama, Kazuo Komiya, Morikazu Kito, Takeshi Tsutsumi, Yuko Isono, Motoi Tobita, Yorimasa Suwa
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Publication number: 20090233274Abstract: The present invention provides novel target proteins and target genes for drug discovery, and the means that enable the development of novel drugs using the same. More particularly, the present invention provides NCS proteins and genes thereof; screening methods for drug (for example, anti-central nervous disease drug); agents for regulating disease (for example, central nervous disease); production methods of a drug derivative; a complex comprising a drug and NCS protein, and a method of producing the complex; a kits comprising a drug or a salt thereof; determination methods for the onset or risk of onset of a specified disease, determination methods for susceptibility to a drug, and determination kits used for the determination methods; and the like.Type: ApplicationFiled: October 9, 2005Publication date: September 17, 2009Applicant: Reverse Proteomics Research Institute Co.Inventors: Tadakazu Yamauchi, Hideaki Sueoka, Koichi Tsuchiya, Katsuhisa Murayama, Ken Horiuchi, Kazuo Komiya, Morikazu Kito, Takeshi Kito, Takeshi Tsutsumi, Yuko Isono, Yorimasa Suwa
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Publication number: 20090143285Abstract: The present invention provides target proteins and target genes for bioactive substances such as drugs, and means that enable the development of novel bioactive substances using the same. More specifically, the present invention provides target proteins and target genes for bioactive substances; screening methods for substances capable of regulating bioactivities; bioactivity regulators; a bioactive substance derivative production method; a complex comprising a bioactive substance and a target protein, and a method of producing the complex; and kits comprising a bioactive substance or a salt thereof; determination methods for the onset or risk of onset of a specified disease or condition, determination methods for susceptibility to a bioactive substance, and determination kits used for the determination methods, and the like.Type: ApplicationFiled: March 24, 2006Publication date: June 4, 2009Applicant: REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD.Inventors: Hideaki Sueoka, Tadakazu Yamauchi, Kouichi Tsuchiya, Katsuhisa Murayama, Morikazu Kito, Takeshi Tsutsumi, Yuko Isono, Kazuo Komiya, Noriyuki Inomata, Yorimasa Suwa, Ken Horiuchi
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Publication number: 20090104691Abstract: The present invention provides a novel adenovirus vector for which inflammation during the in vivo administration thereof is alleviated by inhibiting the induction of expression of an adenovirus gene by a foreign promoter inserted into the adenovirus genome, and a method for producing the vector, a cell line for use in the production of the recombinant adenovirus vector, or a gene therapy method using the recombinant adenovirus vector.Type: ApplicationFiled: September 16, 2008Publication date: April 23, 2009Applicant: Dainippon Sumitomo Pharma Co., Ltd.Inventors: Michio Nakai, Kazuo Komiya, Masashi Murata, Naoki Tohdoh, Izumu Saito
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Patent number: 7445929Abstract: The present invention provides a novel adenovirus vector for which inflammation during the in vivo administration thereof is alleviated by inhibiting the induction of expression of an adenovirus gene by a foreign promoter inserted into the adenovirus genome, and a method for producing the vector, a cell line for use in the production of the recombinant adenovirus vector, or a gene therapy method using the recombinant adenovirus vector.Type: GrantFiled: May 24, 2001Date of Patent: November 4, 2008Assignee: Dainippon Sumitomo Pharma Co., Ltd.Inventors: Michio Nakai, Kazuo Komiya, Masashi Murata, Naoki Tohdoh, Izumu Saito
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Publication number: 20040091456Abstract: The present invention provides a novel adenovirus vector for which inflammation during the in vivo administration thereof is alleviated by inhibiting the induction of expression of an adenovirus gene by a foreign promoter inserted into the adenovirus genome, and a method for producing the vector, a cell line for use in the production of said recombinant adenovirus vector, or a gene therapy method using said recombinant adenovirus vector.Type: ApplicationFiled: November 26, 2002Publication date: May 13, 2004Inventors: Michio Nakai, Kazuo Komiya, Masashi Murata, Naoki Tohdoh, Izumu Saito