Patents by Inventor Kazuo Kumagai

Kazuo Kumagai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10470577
    Abstract: It is provided a seat pad having excellent comfort in seating with improved air permeability and cushion durability in a seat pad of the vehicle seat. The seat pad includes an air permeable member having a ventilation n function with an outside. The seat pad is integrally foam molded using a foamed resin material in a state where the air permeable member is introduced. The seat pad has a surface of the air permeable member projecting with respect to a surface of the seat pad located at a closest position to the air permeable member.
    Type: Grant
    Filed: November 26, 2015
    Date of Patent: November 12, 2019
    Assignees: TACHI-S CO., LTD., BRIDGESTONE CORPORATION
    Inventors: Hideo Tobata, Junpei Yoshikawa, Jun Takano, Kazuo Noguchi, Kenji Kumagai
  • Patent number: 10389626
    Abstract: A transfer device transfers communication data, comprising: a search unit having a first search means that includes a first table and a first search circuit, the search unit referring to the first table using the first search circuit to search for the first transfer destination information from the first destination information; a search control unit that is a reconfigurable mechanism that creates search designation information and executes a first search designation information creation process of creating first search designation information; a control unit that controls the search unit and creates in the search unit at least a second search means including a second table and a second search circuit, the control unit controlling the search control unit to add to the search control unit a second search designation information creation process; and a transfer unit that receives the communication data and transmits the communication data to a transfer destination.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: August 20, 2019
    Assignee: Alaxala Networks Corporation
    Inventors: Takeshi Kumagai, Kazuo Sugai, Shinichi Akahane, Takayuki Muranaka
  • Patent number: 10326705
    Abstract: In a core node, packet related information included in a packet is extracted, a virtual queue length, which is an estimated value of a queue length of a transmission queue addressed to a user in an edge device, is calculated and held on a user basis on the basis of the packet related information and band information of a line between the edge device and the user, and a determination is made, on a user basis, as to whether or not band control is required, on the basis of the virtual queue length and predetermined conditions so as to perform, on the basis of the result of the determination, the band control of the packet addressed to the user on a user basis in a packet relay part.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: June 18, 2019
    Assignee: Alaxala Networks Corporation
    Inventors: Kazuo Sugai, Takeshi Kumagai, Yuichi Ishikawa, Naoya Kumita
  • Publication number: 20160368895
    Abstract: [Problem] The present invention addresses the problem of providing a compound that is useful for preventing or treating diseases associated with malfunctioning of PGI2 receptors, in particular, pulmonary hypertension. [Solution] A positive allosteric regulator of a PGI2 receptor which comprises a compound represented by formula (1) or a pharmaceutically acceptable salt, hydrate or solvate thereof. (1) (In the formula, R1 is a branched chain or cyclic alkyl or alkenyl having 3 to 10 carbon atoms which may be substituted, R2 is a hydrogen atom or an alkyl having 1 to 6 carbon atoms which may be substituted, R3 is 1 to 4 substituents which are the same or different independently selected from the group consisting of a hydrogen atom, a halogen atom, an alkyl having 1 to 6 carbon atoms which may be substituted, and an alkoxy having 1 to 6 carbon atoms which may be substituted, and A is an aryl which may be substituted or a heteroaryl which may be substituted.
    Type: Application
    Filed: November 27, 2014
    Publication date: December 22, 2016
    Applicants: THE UNIVERSITY OF TOKYO, NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY
    Inventors: Tetsuo NAGANO, Takayoshi OKABE, Hirotatsu KOJIMA, Toshifumi SUZUKI, Kenjiro HANAOKA, Manabu SHIMONISHI, Shinichiro EGASHIRA, Hirofumi NAKANO, Kazuo KUMAGAI, Hiroyuki MIYACHI, Kenji MATSUNO, Minoru WAKI
  • Publication number: 20160289728
    Abstract: In a method for detecting fluorescence or absorbance of the present invention, a diaphorase causes reduction from resazurin to resorufin in the presence of an SH reagent and NADH or NADPH, and the resulting fluorescence intensity or absorbance is measured. A method for measuring ADP of the present invention includes a 2-1 process in which glucose is reacted with ADP and an ADP-dependent hexokinase, a 2-2 process in which the glucose-6-phosphate obtained in the 2-1 process is reacted with NAD or NADP and glucose-6-phosphate dehydrogenase, and a 2-3 process in which resazurin is reacted with the NADH or NADPH obtained in the 2-2 process and a diaphorase in the presence of an SH reagent, and the resulting fluorescence intensity or absorbance is measured.
    Type: Application
    Filed: November 21, 2014
    Publication date: October 6, 2016
    Inventors: Kazuo KUMAGAI, Takayoshi OKABE, Hirotatsu KOJIMA, Tetsuo NAGANO
  • Patent number: 7642362
    Abstract: Compounds represented by the general formula (1) wherein R1 and R3 are each independently hydrogen or a carboxyl group and R2 and R4 are each independently hydrogen or a hydroxyl group, or pharmaceutically acceptable salts thereof, which exhibit semaphorin-inhibitory activity and are useful as preventives or remedies for neuropathic and neurodegenerative diseases are provided.
    Type: Grant
    Filed: January 22, 2003
    Date of Patent: January 5, 2010
    Assignee: Dainippon Sumitomo Pharma Co., Ltd.
    Inventors: Kazuo Kumagai, Nobuo Hosotani
  • Publication number: 20090131412
    Abstract: A compound represented by the formula (1) or a pharmaceutically acceptable salt thereof which has a therapeutic or prophylactic effect on an SNS-related disease such as neuropathic pain. (1) wherein R1 and R2 independently represent an alkyl group having 1 to 4 carbon atoms or the like, or R1 and R2 may together form a 5- to 7-membered ring; n represents a numerical number of 1 to 3; A represents a substituted or unsubstituted aryl group or the like or a formula: —N(R5)R6 (wherein R5 and R6 independently represent a substituted or unsubstituted alkyl group or the like); and R3 and R4 independently represent a substituted or unsubstituted alkyl group or the like, or R3 and R4 may together form a substituted or unsubstituted, saturated or unsubstituted nitrogenated heterocyclic ring, provided that both of R1 and R2 are not a hydrogen atom when R3 and R4 together form a piperidine ring.
    Type: Application
    Filed: June 5, 2006
    Publication date: May 21, 2009
    Applicant: DAINIPPON SUMITOMO PHARMA CO., LTD.
    Inventors: Kazuhito Ikeda, Kazuo Kumagai, Katsunori Tsuboi, Nobuhisa Fukuda
  • Patent number: 7317038
    Abstract: To provide a semaphorin inhibitor; a peripheral or central nerve regeneration promoter which contains said semaphorin inhibitor as an active ingredient; and a preventive or remedy for a neuropathic disease and a neurodegenerative disease containing said nerve regeneration promoter, or the like. A low-molecular weight compound, which acts at a concentration of 10 ?g/ml or below to inhibit the growth cone collapse activity of semaphorin such as semaphorin 3A, semaphorin 6C or the like and/or the nerve outgrowth inhibitory activity of semaphorin in a collagen gel and which does not substantially affect cell proliferation, is obtained from the culture of strain SPF-3059 belonging to the genus Penicillium. The low-molecular weight compound with the semaphorin inhibitory activity thus obtained exhibits the in vivo nerve-regeneration promoting action.
    Type: Grant
    Filed: August 24, 2006
    Date of Patent: January 8, 2008
    Assignee: Dainippon Sumitomo Pharma Co., Ltd.
    Inventors: Toru Kimura, Kaoru Kikuchi, Kazuo Kumagai, Nobuo Hosotani, Akiyoshi Kishino
  • Patent number: 7244761
    Abstract: To provide a semaphorin inhibitor; a peripheral or central nerve regeneration promoter which contains said semaphorin inhibitor as an active ingredient; and a preventive or remedy for a neuropathic disease and a neurodegenerative disease containing said nerve regeneration promoter, or the like. A low-molecular weight compound, which acts at a concentration of 10 ?g/ml or below to inhibit the growth cone collapse activity of semaphorin such as semaphorin 3A, semaphorin 6C or the like and/or the nerve outgrowth inhibitory activity of semaphorin in a collagen gel and which does not substantially affect cell proliferation, is obtained from the culture of strain SPF-3059 belonging to the genus Penicillium. The low-molecular weight compound with the semaphorin inhibitory activity thus obtained exhibits the in vivo nerve-regeneration promoting action.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: July 17, 2007
    Assignee: Dainippon Sumitomo Pharma Co., Ltd.
    Inventors: Toru Kimura, Kaoru Kikuchi, Kazuo Kumagai, Nobuo Hosotani, Akiyoshi Kishino
  • Publication number: 20070015820
    Abstract: To provide a semaphorin inhibitor; a peripheral or central nerve regeneration promoter which contains said semaphorin inhibitor as an active ingredient; and a preventive or remedy for a neuropathic disease and a neurodegenerative disease containing said nerve regeneration promoter, or the like. A low-molecular weight compound, which acts at a concentration of 10 ?g/ml or below to inhibit the growth cone collapse activity of semaphorin such as semaphorin 3A, semaphorin 6C or the like and/or the nerve outgrowth inhibitory activity of semaphorin in a collagen gel and which does not substantially affect cell proliferation, is obtained from the culture of strain SPF-3059 belonging to the genus Penicillium. The low-molecular weight compound with the semaphorin inhibitory activity thus obtained exhibits the in vivo nerve-regeneration promoting action.
    Type: Application
    Filed: August 24, 2006
    Publication date: January 18, 2007
    Applicant: Dainippon Sumitomo Pharma Co., Ltd.
    Inventors: Toru Kimura, Kaoru Kikuchi, Kazuo Kumagai, Nobuo Hosotani, Akiyoshi Kishino
  • Publication number: 20050119334
    Abstract: Compounds represented by the general formula (1) wherein R1 and R3 are each independently hydrogen or a carboxyl group and R2 and R4 are each independently hydrogen or a hydroxyl group, or pharmaceutically acceptable salts thereof, which exhibit semaphorin-inhibitory activity and are useful as preventives or remedies for neuropathic and neurodegenerative diseases are provided.
    Type: Application
    Filed: January 22, 2003
    Publication date: June 2, 2005
    Inventors: Kazuo Kumagai, Nobuo Hosotani
  • Publication number: 20030166711
    Abstract: To provide a semaphorin inhibitor; a peripheral or central nerve regeneration promoter which contains said semaphorin inhibitor as an active ingredient; and a preventive or remedy for a neuropathic disease and a neurodegenerative disease containing said nerve regeneration promoter, or the like.
    Type: Application
    Filed: January 28, 2003
    Publication date: September 4, 2003
    Inventors: Toru Kimura, Kaoru Kikuchi, Kazuo Kumagai, Nobuo Hosotani, Akiyoshi Kishino
  • Patent number: 6576656
    Abstract: An oxindole of Formula 1 or a prodrug thereof, or a pharmaceutically acceptable salt thereof is useful for growth hormone releaser: wherein R1, R2, R3 and R4 are independently hydrogen, optionally substituted alkyl etc; R5 is optionally substituted aryl or optionally substituted heteroaryl; Z is —O— or —NH—; one of W1 and W2 is hydrogen, alkyl or —Y—CON(R10)R11; the other of W1 and W2 is n is 1, 2 or 3; m is 0, 1, 2 or 3; Y is single bond or C1-C3 alkylene; R6 and R7 are independently hydrogen, optionally substituted alkyl etc; R8 and R9 are independently hydrogen, optionally substituted alkyl etc; R10 and R11 are independently hydrogen, alkyl etc.
    Type: Grant
    Filed: March 22, 2001
    Date of Patent: June 10, 2003
    Assignee: Sumitomo Pharmaceuticals Co., Ltd.
    Inventors: Teruhisa Tokunaga, Takashi Umezome, W. Ewan Hume, Ryu Nagata, Kazuhiko Okazaki, Yasuyuki Ueki, Kazuo Kumagai
  • Patent number: 5432067
    Abstract: There is disclosed a process for the production of biotin, in which a culture of a microorganism of the genus Sphingomonas, having an ability to produce biotin, is prepared in a medium, and biotin produced and accumulated in the medium is collected. Also disclosed are microorganisms of the genus Sphingomonas, having an ability to produce biotin, which are useful for this production process of the present invention.
    Type: Grant
    Filed: August 25, 1993
    Date of Patent: July 11, 1995
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Kazuo Kumagai, Misao Miki, Emiko Kawano, Satoshi Mitsuda
  • Patent number: 5395758
    Abstract: There is disclosed a process for production of amide compounds which includes converting a nitrile compound into an amide compound using a cultured broth of bacterial cells, or bacterial cells or materials obtainable by treating bacterial cells, the bacterial cells being cells of a microorganism Agrobacterium radiobacter FERM BP-3843, having activity to convert nitrile compounds into corresponding amide compounds.
    Type: Grant
    Filed: April 30, 1993
    Date of Patent: March 7, 1995
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Yoshiki Takashima, Kazuo Kumagai, Satoshi Mitsuda
  • Patent number: 5373172
    Abstract: A semiconducting diamond electroluminescence element comprises an electrically conductive substrate, a semiconducting diamond layer formed on the substrate, an insulating diamond layer formed on the semiconducting diamond layer, a front electrode formed on the insulating diamond layer, and a back electrode formed on the conductive substrate in ohmic contact with the same. The color of light to be emitted by the semiconducting diamond electroluminescence element can readily be determined by changing the impurity content in the semiconducting diamond layer. The luminescence intensity of the semiconducting diamond electroluminescence element can readily be changed by changing the voltage applied across the front and back electrodes without entailing dielectric breakdown.
    Type: Grant
    Filed: January 4, 1993
    Date of Patent: December 13, 1994
    Assignee: Kabushiki Kaisha Kobe Seiko Sho
    Inventors: Koji Kobashi, Koichi Miyata, Kazuo Kumagai, Shigeaki Miyauchi, Yuichi Matsui
  • Patent number: 5358754
    Abstract: A method for forming diamond films by vapor phase synthesis comprising a process of forming the diamond films on a substrate by direct current discharge plasma, in an atmosphere of a reaction gas including a gas containing at least carbon and hydrogen, or in an atmosphere of a mixed gas containing at least a carbon-containing gas and a hydrogen gas, at a gas pressure between 0.1 and 5 Torr and a substrate temperature between 300.degree. and 1000.degree. C.
    Type: Grant
    Filed: July 6, 1992
    Date of Patent: October 25, 1994
    Assignee: Kabushiki Kaisha Kobe Seiko Sho
    Inventors: Koji Kobashi, Shigeaki Miyauchi, Kozo Nishimura, Kazuo Kumagai, Rie Kato
  • Patent number: 5304461
    Abstract: Thin diamond films can be selectively deposited imagewise on a substrate by gas phase synthesis. The substrate may be either a silicon substrate or a basal thin diamond film formed beforehand on a substrate by gas phase synthesis. Where a silicon substrate is used, its surface is first abraded to give a surface roughness suitable for gas phase synthesis of diamond. When a basal thin diamond film is used, a coating material capable of withstanding a temperature higher than a substrate temperature required for gas phase synthesis of diamond and having a high etching selectivity to diamond is needed to cover areas other than where the thin diamond film is to be newly formed. When a lift-off method is used, a thin masking film having a melting point higher than a temperature to be employed for gas phase synthesis of diamond can also be used in place of the coating material described above.
    Type: Grant
    Filed: March 9, 1992
    Date of Patent: April 19, 1994
    Assignee: Kabushiki Kaisha Kobe Seiko Sho
    Inventors: Takayoshi Inoue, Hiroyuki Tachibana, Akimitsu Nakaue, Kazuo Kumagai, Koichi Miyata, Koji Kobashi
  • Patent number: 5298766
    Abstract: A diamond heterojunction diode having an improved rectifying characteristics with a small reverse current and a large forward current. Three layers are formed on a low-resistance p-type silicon substrate by the microwave plasma CVD in the order of a B-doped p type semiconducting diamond layer, an insulating undoped diamond layer (thinner than 1 .mu.m), and an n-type semiconducting silicon layer. Ohmic electrodes are formed on the front side of a n-type semiconducting silicon layer and the back side of a substrate. Under a forward bias, the electric field is applied to the intermediate insulating layer to accelerate the transport of holes and electrons. Under a reversed bias, the energy band has a notch as well as a potential barrier due to the intermediate layer thus preventing holes from transporting from the n-type semiconducting diamond layer to the p-type semiconducting diamond layer, resulting in the improved rectifying characteristics.
    Type: Grant
    Filed: March 20, 1992
    Date of Patent: March 29, 1994
    Assignee: Kabushiki Kaisha Kobe Seiko Sho
    Inventors: Koji Kobashi, Kozo Nishimura, Shigeaki Miyauchi, Kazuo Kumagai, Rie Katoh
  • Patent number: 5160405
    Abstract: Described is an etching method of a diamond film which comprises providing a diamond film in an atmosphere of a gas containing at least oxygen and/or hydrogen and subjecting the diamond film to an irradiation of an electron beam generated by direct current discharge through a pattern of a mask. In this condition, when the diamond film is contacted with the plasma produced by the electron beam in the atmosphere, the unmasked areas are irradiated by the electron beam, and converted to graphite. The graphite is more readily etched by the plasma, so that the diamond film can be etched at a high rate. The etching through a mask ensures a fine etched pattern of the diamond film. In addition, a diamond film with a large area can be etched by this method.
    Type: Grant
    Filed: March 18, 1991
    Date of Patent: November 3, 1992
    Assignee: Kabushiki Kaisha Kobe Seiko Sho
    Inventors: Shigeaki Miyauchi, Koichi Miyata, Kazuo Kumagai, Koji Kobashi