Patents by Inventor Kazuo Kurihara

Kazuo Kurihara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10823982
    Abstract: The purpose of the present invention is to provide a myopia treatment device. A myopia treatment device of the present invention comprises a light transmission part selected from a group consisting of an eyesight correcting tool, an eye protection tool, a face protection tool, a sunshade, a display device, a window, a wall, a light source covering, and a coating material. The light transmission part of the device transmits violet light having a wavelength within a range of 360 nm to 400 nm inclusive and thus treats myopia. Or, the myopia treatment device comprises a light emission part selected from a group consisting of lighting equipment, a display device, and a light irradiation device. The light emission part of the device emits violet light having a wavelength within a range of 360 nm to 400 nm inclusive and thus treats myopia.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: November 3, 2020
    Assignee: TSUBOTA LABORATORY, INC.
    Inventors: Kazuo Tsubota, Kazuno Negishi, Hidemasa Torii, Toshihide Kurihara
  • Publication number: 20200171112
    Abstract: The ophthalmic composition effective for the prevention or treatment of myopia or ocular diseases are provided. In particular, the present invention provides an ophthalmic composition effective in a growing child or a young person in whom myopia develops and progresses, as well as a middle-aged and elderly person in whom age-related ocular diseases such as cataract, glaucoma, retinal detachment, retinopathy, maculopathy, choroidal neovascularization, posterior staphyloma, and optic neuropathy develop, a functional food containing the ophthalmic composition, and a screening method capable of searching for the same. [Solution] The above problem is solved by an ophthalmic composition or functional food product containing at least one component selected from the group consisting of crocetin and its pharmaceutically acceptable salts and ginkgo leaf extract.
    Type: Application
    Filed: May 15, 2018
    Publication date: June 4, 2020
    Inventors: Kazuo TSUBOTA, Toshihide KURIHARA
  • Publication number: 20200150457
    Abstract: A model that closely resembles human excessive myopia can be prepared by mounting a minus lens (2) and a protector (4) to a juvenile mouse, the minus lens having an angle and a width adjustable in response to growth of the mouse. Further, this model analysis shows that myopia induction causes endoplasmic reticulum stress in a sclera and the endoplasmic reticulum stress induces myopia. Furthermore, it is revealed that an endoplasmic reticulum stress suppressant, particularly, phenylbutyrate and tauroursodeoxycholic acid act as a myopia prevention/suppression agent.
    Type: Application
    Filed: September 5, 2019
    Publication date: May 14, 2020
    Applicant: TSUBOTA LABORATORY, INC.
    Inventors: Shinichi IKEDA, Xiaoyan JIANG, Kazuo TSUBOTA, Toshihide KURIHARA
  • Publication number: 20190365760
    Abstract: Novel HIF inhibitors having low cytotoxicity and suitable for ophthalmologic treatment and agents for the treatment or prevention of ischemic diseases, glaucoma, optic nerve diseases, retinal degenerative diseases, retinal degenerative diseases, angiogenic retinal diseases, cancer, neurodegenerative or autoimmune diseases are provided. The present invention is a therapeutic or prophylactic agent for ischemic disease, glaucoma, optic nerve disease, retinal degenerative disease, retinal degenerative disease, angiogenic retinal disease, cancer, neurodegenerative disease, or autoimmune disease, which comprises as an active ingredient one or more or an extract thereof selected from the group consisting of plants belonging to the genus Asian, plants belonging to the genus Swiss, plants belonging to the genus Grape, plants belonging to the genus Brassica, fish belonging to the genus Kivinago, and so on.
    Type: Application
    Filed: November 14, 2017
    Publication date: December 5, 2019
    Inventors: Toshihide KURIHARA, Yukihiro MIWA, Kazuo TSUBOTA, Hiroyoshi INOUE
  • Patent number: 10426900
    Abstract: A method for measuring an amount of pain involves positioning a needle adjacent a non-human animal which is under anesthesia, inserting the needle at a controlled puncture speed into skin of the non-human animal, and measuring a muscle action potential of a muscle portion of the non-human animal produced by the insertion of the needle. The muscle action potential is measured from insertion start, at which the insertion of the needle into the skin is started, to insertion stop, at which the insertion of the needle into the skin is stopped.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: October 1, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Kazuo Okamoto, Nozomi Ami, Tadakatsu Isozaki, Daichi Kurihara
  • Publication number: 20190194294
    Abstract: The purpose of the present invention is to provide an agent for restoring a visual function or an agent for preventing the deterioration in a visual function, which has an excellent visual function restoring ability. The agent for regenerating a visual function or the agent for preventing the deterioration in a visual function according to the present invention contains, as an active ingredient, a chimeric protein having both an amino acid sequence for a microorganism-origin ion-transporting receptor rhodopsin and an amino acid sequence for an animal-origin G-protein-coupled receptor rhodopsin. The chimeric protein is preferably one in which an amino acid sequence for a cytoplasm-side second loop and/or a cytoplasm-side third loop in the amino acid sequence for the microorganism-origin ion-transporting receptor rhodopsin is substituted by an amino acid sequence for a cytoplasm-side second loop and/or a cytoplasm-side third loop in the G-protein-coupled receptor rhodopsin.
    Type: Application
    Filed: September 1, 2017
    Publication date: June 27, 2019
    Inventors: Toshihide Kurihara, Yusaku Katada, Hiromitsu Kunimi, Kazuo Tsubota, Hideki Kandori
  • Publication number: 20120160028
    Abstract: Provided is a vibration gyro sensor including: a vibration element including a piezoelectric element group which has a first side provided with a drive electrode and a detection electrode and a second side opposed to the first side and provided with a common electrode, which vibrates by a drive signal input between the drive electrode and the common electrode and generates an output signal containing a detection signal corresponding to Coriolis force from the detection electrode; a bias section applying a bias voltage to the detection electrode; an oscillation circuit outputting the signal for causing vibration of the vibration element to the drive electrode as the drive signal based on the output signal generated by the detection electrode; and a phase inversion circuit outputting an inversion signal obtained by inverting a phase of the drive signal output from the oscillation circuit to the common electrode.
    Type: Application
    Filed: March 2, 2012
    Publication date: June 28, 2012
    Applicant: SONY CORPORATION
    Inventor: Kazuo Kurihara
  • Patent number: 8136398
    Abstract: Provided is a vibration gyro sensor including: a vibration element including a piezoelectric element group which has a first side provided with a drive electrode and a detection electrode and a second side opposed to the first side and provided with a common electrode, which vibrates by a drive signal input between the drive electrode and the common electrode and generates an output signal containing a detection signal corresponding to Coriolis force from the detection electrode; a bias section applying a bias voltage to the detection electrode; an oscillation circuit outputting the signal for causing vibration of the vibration element to the drive electrode as the drive signal based on the output signal generated by the detection electrode; and a phase inversion circuit outputting an inversion signal obtained by inverting a phase of the drive signal output from the oscillation circuit to the common electrode.
    Type: Grant
    Filed: January 7, 2008
    Date of Patent: March 20, 2012
    Assignee: Sony Corporation
    Inventor: Kazuo Kurihara
  • Patent number: 8033171
    Abstract: A detection apparatus is provided which includes a cantilever vibration gyro including a piezoelectric element having a first side provided with a drive electrode and a pair of detection electrodes sandwiching the drive electrode with predetermined gaps therebetween and a second side opposed to the first side and provided with a common electrode, which vibrates by a drive signal input between the drive electrode and the common electrode and generates a pair of detected signals corresponding to Coriolis force from the detection electrodes. The detection apparatus also includes a bias applying section for applying a bias voltage to the detection electrodes, an adding section adding the pair of detected signals, a first phase delay section delaying a phase of the detected signal obtained by the addition by a range larger than 45° and smaller than 90°, and an amplitude control section controlling the delayed detected signal to a predetermined voltage amplitude to output as the drive signal.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: October 11, 2011
    Assignee: Sony Corporation
    Inventor: Kazuo Kurihara
  • Patent number: 8001840
    Abstract: There is provided an oscillation type gyro sensor including an oscillation gyro device, an oscillation circuit, a controller, and an impedance conversion circuit. The oscillation gyro device includes a piezoelectric device including a drive electrode and a detection electrode, oscillates according to a drive signal input to the drive electrode, and is capable of generating an output signal including a detection signal corresponding to a Coriolis force from the detection electrode. The oscillation circuit outputs, based on the output signal, a signal for oscillating the oscillation gyro device to the drive electrode as the drive signal. The controller controls the oscillation circuit such that the oscillation circuit outputs a drive signal that makes the output signal constant. To the impedance conversion circuit, the drive signal output from the oscillation circuit is input.
    Type: Grant
    Filed: March 12, 2008
    Date of Patent: August 23, 2011
    Assignee: Sony Corporation
    Inventor: Kazuo Kurihara
  • Publication number: 20100302385
    Abstract: An angular velocity sensor includes a sensor device and an amplification circuit. The sensor device generates a detection signal corresponding to an angular velocity. The amplification circuit generates both a first output signal by non-inverting amplifying the detection signal with a first gain and a second output signal by inverting-amplifying the detection signal with the first gain, and outputs the first output signal and the second output signal in order to obtain an angular velocity signal by calculating a difference between the first output signal and the second output signal.
    Type: Application
    Filed: April 26, 2010
    Publication date: December 2, 2010
    Applicant: Sony Corporation
    Inventor: Kazuo KURIHARA
  • Patent number: 7819973
    Abstract: A method comprising the steps of continuously changing the concentrations in solution of a biomacromolecule to be crystallized and a precipitant, thereby constructing a crystal phase diagram containing a solubility curve, searching for optimum conditions of crystallization on the basis of the constructed crystal phase diagram, and performing efficient growth of the crystal of the biomacromolecule. Also disclosed is an apparatus for implementing the method.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: October 26, 2010
    Assignee: Japan Atomic Energy Research Institute
    Inventors: Nobuo Niimura, Yuki Onishi, Shigeki Arai, Toshiyuki Chatake, Mitsuru Maeda, Kazuo Kurihara
  • Patent number: 7665360
    Abstract: Vibration gyro circuitry, a vibration gyro unit, and a method for detecting a vibration gyro output, which enable detection of a rotational angular velocity with high sensitivity, are provided. The circuitry and the unit includes a differential amplifier circuit (4) for outputting a signal Vda corresponding to a difference (Vgl?Vgr) between output signals of two detection pieces of a vibration gyro (31), a synchronous detection circuit (5) for synchronously detecting the output signal Vda of the differential amplifier circuit (4), and a phase shift circuit for supplying to the synchronous detection circuit (5) a signal, as a timing signal Vck for the synchronous detection, which is phase-shifted with respect to a drive signal (an output signal of an adding circuit 1) Vsa supplied to the vibration gyro (31).
    Type: Grant
    Filed: September 28, 2005
    Date of Patent: February 23, 2010
    Assignee: Sony Corporation
    Inventor: Kazuo Kurihara
  • Publication number: 20090320593
    Abstract: A vibration type gyro sensor according to the present invention includes vibrating elements 1X and 1Y which detect angular velocities, a support substrate 2 which is electrically connected to the vibrating elements 1X and 1Y and which supports the vibrating elements 1X and 1Y, a relay substrate 4 which is electrically connected to the support substrate 2 and which includes external connection terminals 3, and buffer members 5 which are disposed between the support substrate 2 and the relay substrate 4 and which suppress transmission of strain and vibration between the support substrate 2 and the relay substrate 4. The vibration type gyro sensor is capable of stabilizing vibration characteristics without being influenced by strain and vibration.
    Type: Application
    Filed: June 29, 2007
    Publication date: December 31, 2009
    Applicant: SONY CORPORATION
    Inventors: Eiji Nakashio, Shigeto Watanabe, Shin Sasaki, Teruo Inaguma, Junichi Honda, Kazuo Kurihara, Yuji Shishido, Tomoyuki Takahashi
  • Publication number: 20080282800
    Abstract: A detection apparatus is provided which includes a cantilever vibration gyro including a piezoelectric element having a first side provided with a drive electrode and a pair of detection electrodes sandwiching the drive electrode with predetermined gaps therebetween and a second side opposed to the first side and provided with a common electrode, which vibrates by a drive signal input between the drive electrode and the common electrode and generates a pair of detected signals corresponding to Coriolis force from the detection electrodes. The detection apparatus also includes a bias applying section for applying a bias voltage to the detection electrodes, an adding section adding the pair of detected signals, a first phase delay section delaying a phase of the detected signal obtained by the addition by a range larger than 45° and smaller than 90°, and an amplitude control section controlling the delayed detected signal to a predetermined voltage amplitude to output as the drive signal.
    Type: Application
    Filed: May 8, 2008
    Publication date: November 20, 2008
    Applicant: SONY CORPORATION
    Inventor: Kazuo Kurihara
  • Publication number: 20080276708
    Abstract: Vibration gyro circuitry, a vibration gyro unit, and a method for detecting a vibration gyro output, which enable detection of a rotational angular velocity with high sensitivity, are provided. The circuitry and the unit includes a differential amplifier circuit (4) for outputting a signal Vda corresponding to a difference (Vgl?Vgr) between output signals of two detection pieces of a vibration gyro (31), a synchronous detection circuit (5) for synchronously detecting the output signal Vda of the differential amplifier circuit (4), and a phase shift circuit for supplying to the synchronous detection circuit (5) a signal, as a timing signal Vck for the synchronous detection, which is phase-shifted with respect to a drive signal (an output signal of an adding circuit 1) Vsa supplied to the vibration gyro (31).
    Type: Application
    Filed: September 28, 2005
    Publication date: November 13, 2008
    Inventor: Kazuo Kurihara
  • Publication number: 20080223138
    Abstract: There is provided an oscillation type gyro sensor including an oscillation gyro device, an oscillation circuit, a controller, and an impedance conversion circuit. The oscillation gyro device includes a piezoelectric device including a drive electrode and a detection electrode, oscillates according to a drive signal input to the drive electrode, and is capable of generating an output signal including a detection signal corresponding to a Coriolis force from the detection electrode. The oscillation circuit outputs, based on the output signal, a signal for oscillating the oscillation gyro device to the drive electrode as the drive signal. The controller controls the oscillation circuit such that the oscillation circuit outputs a drive signal that makes the output signal constant. To the impedance conversion circuit, the drive signal output from the oscillation circuit is input.
    Type: Application
    Filed: March 12, 2008
    Publication date: September 18, 2008
    Applicant: SONY CORPORATION
    Inventor: Kazuo Kurihara
  • Publication number: 20080163684
    Abstract: Provided is a vibration gyro sensor including: a vibration element including a piezoelectric element group which has a first side provided with a drive electrode and a detection electrode and a second side opposed to the first side and provided with a common electrode, which vibrates by a drive signal input between the drive electrode and the common electrode and generates an output signal containing a detection signal corresponding to Coriolis force from the detection electrode; a bias section applying a bias voltage to the detection electrode; an oscillation circuit outputting the signal for causing vibration of the vibration element to the drive electrode as the drive signal based on the output signal generated by the detection electrode; and a phase inversion circuit outputting an inversion signal obtained by inverting a phase of the drive signal output from the oscillation circuit to the common electrode.
    Type: Application
    Filed: January 7, 2008
    Publication date: July 10, 2008
    Applicant: SONY CORPORATION
    Inventor: Kazuo Kurihara
  • Patent number: 7210349
    Abstract: The present invention provides a drive circuit of an oscillation gyro including two piezoelectric elements formed in an oscillator, which includes an adding circuit for supplying a drive signal to one side faces of the two piezoelectric elements and adding signals obtained from the other side faces opposed to the one side faces of the piezoelectric elements, and an oscillation circuit adapted to be fed back with an addition output signal obtained by the adding circuit, wherein a sine wave signal obtained as an oscillation output of the oscillation circuit is supplied to the one side faces of the two piezoelectric elements as the drive signal. Thus, the drive circuit of the oscillation gyro which obtains the stable output with the simple configuration can be provided.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: May 1, 2007
    Assignee: Sony Corporation
    Inventors: Kazuo Kurihara, Yoshinori Satoh, Toshiyuki Kawamura, Toru Matsunaga
  • Patent number: D725546
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: March 31, 2015
    Inventor: Ted Kazuo Kurihara