Patents by Inventor Kazuo Ohishi
Kazuo Ohishi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7973076Abstract: The present invention provides compositions having, as active ingredients, a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.Type: GrantFiled: December 15, 2008Date of Patent: July 5, 2011Assignee: Ajinomoto Co., Inc.Inventors: Yoshihiro Morinaga, Yukio Nihei, Yasuyo Suga, Manabu Suzuki, Kazuo Ohishi, Akira Okano
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Publication number: 20100069486Abstract: The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.Type: ApplicationFiled: November 20, 2009Publication date: March 18, 2010Applicant: Ajinomoto Co., Inc.Inventors: Yoshihiro Morinaga, Yukio Nihei, Yasuyo Suga, Manabu Suzuki, Kazuo Ohishi, Akira Okano
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Patent number: 7655696Abstract: The present invention provides composition having as active ingredients a stilbene derivatively and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.Type: GrantFiled: August 4, 2005Date of Patent: February 2, 2010Assignee: Ajinomoto Co., Inc.Inventors: Yoshihiro Morinaga, Yukio Nihei, Yasuyo Suga, Manabu Suzuki, Kazuo Ohishi, Akira Okano
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Publication number: 20090093540Abstract: The present invention provides compositions having, as active ingredients, a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.Type: ApplicationFiled: December 15, 2008Publication date: April 9, 2009Applicant: Ajinomoto Co., Inc.Inventors: Yoshihiro MORINAGA, Yukio Nihei, Yasuyo Suga, Manabu Suzuki, Kazuo Ohishi, Akira Okano
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Patent number: 6992106Abstract: The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.Type: GrantFiled: June 12, 2002Date of Patent: January 31, 2006Assignee: Ajinomoto Co., Inc.Inventors: Yoshihiro Morinaga, Yukio Nihei, Yasuyo Suga, Manabu Suzuki, Kazuo Ohishi, Akira Okano
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Publication number: 20050281892Abstract: The present invention provides composition having as active ingredients a stilbene derivatively and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.Type: ApplicationFiled: August 4, 2005Publication date: December 22, 2005Applicant: Ajinomoto Co., Inc.Inventors: Yoshihiro Morinaga, Yukio Nihei, Yasuyo Suga, Manabu Suzuki, Kazuo Ohishi, Akira Okano
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Publication number: 20020193434Abstract: The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.Type: ApplicationFiled: May 29, 2002Publication date: December 19, 2002Applicant: AJINOMOTO CO. INCInventors: Yoshihiro Morinaga, Yukio Nihei, Yasuyo Suga, Manabu Suzuki, Kazuo Ohishi, Akira Okano
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Publication number: 20020193362Abstract: The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.Type: ApplicationFiled: June 12, 2002Publication date: December 19, 2002Applicant: AJINOMOTO CO. INCInventors: Yoshihiro Morinaga, Yukio Nihei, Yasuyo Suga, Manabu Suzuki, Kazuo Ohishi, Akira Okano
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Patent number: 6462087Abstract: The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.Type: GrantFiled: October 3, 2000Date of Patent: October 8, 2002Assignee: Ajinomoto Co., Inc.Inventors: Yoshihiro Morinaga, Yukio Nihei, Yasuyo Suga, Manabu Suzuki, Kazuo Ohishi, Akira Okano
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Patent number: 5731353Abstract: A stilbene derivative of the following general formula (I) or a pharmaceutically acceptable acid addition salt thereof have low toxicity, but are water soluble and effective as carcinostatics: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, each represent an alkyl group having 1 to 3 carbon atoms; X represents a hydrogen atom or a nitrile group; Y represents an alkyloxy group having 1 to 3 carbon atoms, an alkyl group having 1 to 6 carbon atoms or a halogen atom.Type: GrantFiled: March 8, 1996Date of Patent: March 24, 1998Assignee: Ajinomoto Co., Inc.Inventors: Koji Ohsumi, Takashi Tsuji, Yoshihiro Morinaga, Kazuo Ohishi
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Patent number: 5674906Abstract: Stilbene compounds of the following formula (I) or their pharmaceutically acceptable salts are effective as carcinostatics and of low toxicity: ##STR1## wherein X represents a hydrogen atom or a nitrile group, and Y represents an amino acid acyl group.Type: GrantFiled: March 7, 1996Date of Patent: October 7, 1997Assignee: Ajinomoto Co., Inc.Inventors: Toshihiro Hatanaka, Koji Ohsumi, Takashi Tsuji, Yukio Nihei, Ryusuke Nakagawa, Kazuo Ohishi
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Patent number: 5525632Abstract: A stilbene derivative of the following general formula (I) or a pharmaceutically acceptable acid addition salt thereof have low toxicity, but are water soluble and effective as carcinostatics: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, each represent an alkyl group having 1 to 3 carbon atoms; X represents a hydrogen atom or a nitrile group; Y represents an alkyloxy group having 1 to 3 carbon atoms, an alkyl group having 1 to 6 carbon atoms or a halogen atom.Type: GrantFiled: September 8, 1994Date of Patent: June 11, 1996Assignee: Ajinomoto Co., Ltd.Inventors: Koji Obsumi, Takashi Tsuji, Yoshihiro Morinaga, Kazuo Ohishi
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Patent number: 5292757Abstract: 1,4-dihydropyridine derivatives of Formula 1 or pharmaceutically acceptable salts thereof: ##STR1## wherein the substituents are disclosed herein and which are useful against tumor cells which have acquired resistance to one or more drugs used as chemotherapeutic agents.Type: GrantFiled: April 24, 1992Date of Patent: March 8, 1994Assignee: Ajinomoto Company, Inc.Inventors: Koji Ohsumi, Takaaki Sekiyama, Ryusuke Nakagawa, Takashi Tsuji, Yoshihiro Morinaga, Kazuo Ohishi
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Patent number: 5041579Abstract: Platinum complexes of cis-diaminocyclohexanol or cis-diaminocyclohexane, with the exclusion of platinum complexes of 2-deoxystreptamine, having high anti-tumor activity, low toxicity, water-solubility and exhibiting no cross-resistance to cis-platin.Type: GrantFiled: September 23, 1988Date of Patent: August 20, 1991Assignee: Ajinomoto Co., Inc.Inventors: Seiichi Nishi, Kazuo Ohishi, Kunisuke Izawa, Tsuyoshi Shiio, Tetsuo Suami