Abstract: In a valve opening/closing timing control device, a fluid pressure chamber formed by a drive-side rotating and a driven-side rotating body is divided into an advance chamber and a delay chamber. The valve opening/closing timing control device includes an intermediate lock mechanism; an electromagnetic valve; a phase detection sensor; and a control unit that issues a command to the electromagnetic valve to switch a working fluid supply destination to a working fluid supply destination at which the driven-side rotating body shifts to an intermediate lock phase, when a relative rotation phase at the startup of an engine is positioned toward a most delayed phase or a most advanced phase with respect to the intermediate lock phase in case of the electromagnetic valve that sets the working fluid supply destination to the delay chamber or the advance chamber when supply of electric power to the electromagnetic valve is stopped.

Abstract: A control device is configured that can shorten the time required for a system to stop due to an ignition switch operation in a situation in which the internal combustion engine is stopped due to stop control. The control device includes a control unit that, in the situation in which the internal combustion engine is stopped due to stop control, if the transmission mechanism is operated to a second shift position that is different from a first shift position in which the vehicle can travel, executes phase conversion control to shift a valve opening/closing timing control mechanism from a first lock phase to a second lock phase.

Abstract: A control device is configured that can shorten the time required for a system to stop due to an ignition switch operation in a situation in which the internal combustion engine is stopped due to stop control. The control device includes a control unit that, in the situation in which the internal combustion engine is stopped due to stop control, if the transmission mechanism is operated to a second shift position that is different from a first shift position in which the vehicle can travel, executes phase conversion control to shift a valve opening/closing timing control mechanism from a first lock phase to a second lock phase.

Abstract: A valve timing control device includes: a driving side rotating body rotating in synchronization with a crankshaft of an internal combustion engine(E); a driven side rotating body rotating integrally with a camshaft of the internal combustion engine and capable of rotating relative to the driving side rotating body; a fluid pressure chamber formed by the driving side rotating body and the driven side rotating body; a partition portion arranged in the fluid pressure chamber and partitioned into a retard chamber and an advance chamber an intermediate lock mechanism including a concave portion a lock member; and a phase control unit controlling the supply of a fluid to the retard chamber and the discharge of the fluid from the advance chamber or the supply of the fluid to the advance chamber and the discharge of the fluid from the retard chamber.

Abstract: In a valve opening/closing timing control device, a fluid pressure chamber formed by a drive-side rotating and a driven-side rotating body is divided into an advance chamber and a delay chamber. The valve opening/closing timing control device includes an intermediate lock mechanism; an electromagnetic valve; a phase detection sensor; and a control unit that issues a command to the electromagnetic valve to switch a working fluid supply destination to a working fluid supply destination at which the driven-side rotating body shifts to an intermediate lock phase, when a relative rotation phase at the startup of an engine is positioned toward a most delayed phase or a most advanced phase with respect to the intermediate lock phase in case of the electromagnetic valve that sets the working fluid supply destination to the delay chamber or the advance chamber when supply of electric power to the electromagnetic valve is stopped.

Abstract: A valve opening/closing timing control device includes a driving rotating body that rotates in synchronization with a crankshaft, a driven rotating body that rotates integrally with a camshaft, a phase detection mechanism that detects the relative rotation phase of the driving rotating body and the driven rotating body, a retarding chamber and an advancing chamber between the driving rotating body and the driven rotating body, a lock mechanism capable of constraining the relative rotation phase to a lock phase, a supply/discharge mechanism that supplies/discharges working fluid to/from the advancing chamber, the retarding chamber, and the lock mechanism, and a control unit that controls operation of the supply/discharge mechanism. At startup of the engine, if the detected relative rotation phase is not at the lock phase, the control unit controls the supply/discharge mechanism so as to stop successive supply of working fluid to the retarding and advancing chambers.

Abstract: The present invention relates to a brush type contact material, including one or more curved metal pawls of which ends come into contact with objects to be contacted. The ends of the pawls have an arc-like cross section in a thickness direction, a curvature radius R1 on a front side from a contact point with the object to be contacted and a curvature radius R2 on a back side from the contact point are formed so as to be R1?R2, and also both ends in a width direction of the pawl are chamfered. At this time, preferably, R1 is larger than R2 (R1>R2), and R1 divided by R2 (R1/R2) is 3.0 or less. The brush type contact material according to the present invention enables a smoother sliding movement than ever before and can be relatively simply manufactured.

Abstract: An internal combustion engine includes a variable valve timing control apparatus including a driving-side rotating member rotating about a rotary axis by rotational force transmitted from a crankshaft, a driven-side rotating member including at least one fluid pressure chambers partitioned and formed with at least one advanced angle chambers and at least one retarded angle chambers and integrally rotating with a camshaft for opening and closing a valve, and a lock mechanism configured with a lock member provided at one of the driving-side rotating member and the driven-side rotary member to be engageable and disengageable with a recessed portion formed at the other of the driving-side rotating member and the driven-side rotary member, and an engine control unit for stopping the internal combustion engine to position a portion where the lock mechanism is formed below a virtual line passing through the rotary axis when the internal combustion engine is stopped.

Abstract: A composition having BACE 1 inhibitory activity containing a compound represented by the general formula (I): wherein ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; E is lower alkylene; X is S, O, or NR1; R1 is a hydrogen atom or lower alkyl; R2a, R2b, R3a, R3b, R4a and R4b is each independently a hydrogen atom, halogen, or hydroxy etc.; n and m are each independently an integer of 0 to 3; n+m is an integer of 0 to 3; R5 is a hydrogen atom or substituted lower alkyl; its pharmaceutically acceptable salt, or a solvate thereof.

Abstract: A composition having BACE 1 inhibitory activity containing a compound represented by the formula (I): wherein ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; E is lower alkylene; X is S, O, or NR1; R1 is a hydrogen atom or lower alkyl; R2a, R2b, R3a, R3b, R4a, and R4b, is each independently a hydrogen atom, halogen, or hydroxyl etc.; n and m are each independently an integer of 0 to 3; n+m is an integer of 0 to 3; R5 is a hydrogen atom or substituted lower alkyl; its pharmaceutically acceptable salt or a solvate thereof.

Abstract: A valve timing control apparatus includes a driving-side rotation member, a driven-side rotation member, a first lock mechanism selectively achieving a first lock state in which a relative rotation phase of the driven-side rotation member relative to the driving-side rotation member is locked at an intermediate lock phase and a first lock release state, and a second lock mechanism selectively achieving a second lock state in which the relative rotation phase is locked at one of a most advanced angle phase and a most retarded angle phase and a second lock release state, the driven-side rotation member being rotatable relative to the driving-side rotation member by a first clearance angle in the first lock state, the driven-side rotation member being rotatable relative to the driving-side rotation member by a second clearance angle in the second lock state, the second clearance angle being smaller than the first clearance angle.

Abstract: A valve opening-closing timing control apparatus includes a partition portion partitioning a fluid pressure chamber into an advanced angle chamber and a retarded angle chamber, a phase control portion controlling a rotational phase of a driven-side rotational member relative to a driving-side rotational member, a lock mechanism including a lock member and a lock recess for locking the rotational phase at a predetermined phase, a lock control portion switching the lock mechanism between a locked state and an unlocked state by supplying and discharging a pressurized fluid to and from the lock recess, a phase controlling supply passage supplying the pressurized fluid to the advanced angle chamber and the retarded angle chamber, a lock controlling supply passage supplying the pressurized fluid to the lock recess, and a one-way valve blocking the pressurized fluid supplied to the lock controlling supply passage from flowing into the phase controlling supply passage.

Abstract: Provided is a valve open/close timing control device including, a drive-side rotating body, a driven-side rotating body, a fluid pressure chamber, a partition portion, a fluid control valve part, a first locking mechanism which is capable of restraining a relative rotational phase of the driven-side rotating body relative to the drive-side rotating body at a first predetermined phase between a most retarded angle phase and a most advanced angle phase, and a second locking mechanism which is capable of restraining the relative rotational phase at a second predetermined phase on a more retarded angle side than the first predetermined phase, in which the relative rotational phase is changed to the first predetermined phase when a shift lever position is changed to a parking range.

Abstract: A pharmaceutical composition for treating Alzheimer's disease containing a compound represented by the general formula (I): wherein ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; E is lower alkylene, etc.; X is S, O, or NR1; R1 is a hydrogen atom or lower alkyl; R2, R2b, R3a, R3b, R4a and R4b are each independently a hydrogen atom, halogen, hydroxy, etc.; n and m are each independently an integer of 0 to 3; n+m is an integer of 1 to 3; and R5 is a hydrogen atom, optionally substituted lower alkyl, etc.; its pharmaceutically acceptable salt, or a solvate thereof as an active ingredient.

Abstract: Provided is a valve open/close timing control system where a valve open/close timing control device includes a drive-side rotating member, a driven-side rotating member, a relative rotational phase control mechanism, and a first locking member, in which the internal combustion engine is configured to be started by a drive force generated by a traveling motor or by a drive force generated by a starter motor, and the valve open/close timing control system also includes a control unit which is configured, for starting the internal combustion engine while changing the relative rotational phase at the time of starting the internal combustion engine, to drive the starter motor or the traveling motor at the time of starting the internal combustion engine at the first locking phase, and to drive the traveling motor at the time of starting the internal combustion engine at the second locking phase.

Abstract: An internal combustion engine includes a variable valve timing control apparatus including a driving-side rotating member rotating about a rotary axis by rotational force transmitted from a crankshaft, a driven-side rotating member including at least one fluid pressure chambers partitioned and formed with at least one advanced angle chambers and at least one retarded angle chambers and integrally rotating with a camshaft for opening and closing a valve, and a lock mechanism configured with a lock member provided at one of the driving-side rotating member and the driven-side rotary member to be engageable and disengageable with a recessed portion formed at the other of the driving-side rotating member and the driven-side rotary member, and an engine control unit for stopping the internal combustion engine to position a portion where the lock mechanism is formed below a virtual line passing through the rotary axis when the internal combustion engine is stopped.

Abstract: A valve timing control apparatus includes a driving-side rotation member, a driven-side rotation member, a first lock mechanism selectively achieving a first lock state in which a relative rotation phase of the driven-side rotation member relative to the driving-side rotation member is locked at an intermediate lock phase and a first lock release state, and a second lock mechanism selectively achieving a second lock state in which the relative rotation phase is locked at one of a most advanced angle phase and a most retarded angle phase and a second lock release state, the driven-side rotation member being rotatable relative to the driving-side rotation member by a first clearance angle in the first lock state, the driven-side rotation member being rotatable relative to the driving-side rotation member by a second clearance angle in the second lock state, the second clearance angle being smaller than the first clearance angle.

Abstract: A valve timing control apparatus includes a driving-side rotation member, a driven-side rotation member, and a lock mechanism including a recess portion, a lock member engageable and disengageable relative to the recess portion, and a biasing member. The recess portion includes a lock groove portion with which the lock member is configured to engage to lock a relative rotation phase at a lock phase, and a restriction groove portion. The lock groove portion includes a lock bottom surface and the restriction groove portion includes a restriction bottom surface. A second depth from an opening position of the recess portion to the restriction bottom surface is smaller than a first depth from the opening position to the lock bottom surface. The second depth from the opening position to the restriction bottom surface is smaller than a third depth from the restriction bottom surface to the lock bottom surface.

Abstract: Provided is a valve timing control device, including: a drive side rotating member, a driven side rotating member, fluid pressure chambers, partition portions, advanced angle control oil passages, retarded angle control oil passages, an intermediate lock mechanism, and a retarded angle lock mechanism, in which the intermediate lock mechanism is configured to include a single intermediate lock member, a biasing mechanism which biases the intermediate lock member, and an intermediate fitting depression portion, and the retarded angle lock mechanism is configured to include a single retarded angle lock member, a biasing mechanism which biases the retarded angle lock member, and a retarded angle fitting depression portion.

Abstract: A composition having BACE 1 inhibitory activity containing a compound represented by the general formula (I): wherein ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; E is lower alkylene; X is S, O, or NR1; R1 is a hydrogen atom or lower alkyl; R2a, R2b, R3a, R3b, R4a and R4b is each independently a hydrogen atom, halogen, or hydroxy etc.; n and m are each independently an integer of 0 to 3; n+m is an integer of 0 to 3; R5 is a hydrogen atom or substituted lower alkyl; its pharmaceutically acceptable salt, or a solvate thereof.