Patents by Inventor Kazusa Yoshikai

Kazusa Yoshikai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridonecarboxylic acid derivatives or salts thereof
    Patent number: 7713997
    Abstract: The present invention provides an agent which exhibits excellent antibacterial activity, low toxicity, improved bioavailability, and low binding rate to serum proteins. The present invention is directed to a pyridonecarboxylic acid derivative represented by formula (1): or a salt thereof, wherein R1 represents a methyl group, a fluorine atom, or a chlorine atom; R2 represents a hydrogen atom or a lower alkyl group; R3 represents an isopropyl group or a tert-butyl group; R4 represents a methyl group or a halogen atom; and R5 represents a fluorine atom or a chlorine atom. The present invention is also directed to an antibacterial agent and a medicament containing the derivative or the salt thereof as an active ingredient.
    Type: Grant
    Filed: November 17, 2005
    Date of Patent: May 11, 2010
    Assignee: Wakunaga Pharmaceutical Co., Ltd.
    Inventors: Akira Yazaki, Yasuhiro Kuramoto, Kenji Itoh, Kazusa Yoshikai, Yuzo Hirao, Yoshihiro Ohshita, Norihiro Hayashi, Hirotaka Amano, Takayuki Amago, Hitomi Takenaka
  • NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF
    Publication number: 20090149440
    Abstract: The present invention provides an agent which exhibits excellent antibacterial activity, low toxicity, improved bioavailability, and low binding rate to serum proteins. The present invention is directed to a pyridonecarboxylic acid derivative represented by formula (1): or a salt thereof, wherein R1 represents a methyl group, a fluorine atom, or a chlorine atom; R2 represents a hydrogen atom or a lower alkyl group; R3 represents an isopropyl group or a tert-butyl group; R4 represents a methyl group or a halogen atom; and R5 represents a fluorine atom or a chlorine atom. The present invention is also directed to an antibacterial agent and a medicament containing the derivative or the salt thereof as an active ingredient.
    Type: Application
    Filed: November 17, 2005
    Publication date: June 11, 2009
    Applicant: WAKUNAGA PHARMACEUTICAL CO., LTD
    Inventors: Akira Yazaki, Yasuhiro Kuramoto, Kenji Itoh, Kazusa Yoshikai, Yuzo Hirao, Yoshihiro Ohshita, Norihiro Hayashi, Hirotaka Amano, Takayuki Amago, Hitomi Takenaka