Patents by Inventor Kazushi Araki

Kazushi Araki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition used for treatment of HTLV-1-associated myelopathy
    Patent number: 11311524
    Abstract: The present invention provides a pharmaceutical composition containing an inhibitor selected from the group consisting of an EZH1 inhibitor, an EZH2 inhibitor and an EZH1/2 dual inhibitor as an active ingredient, for use in treating HTLV-1-associated myelopathy. The present invention provides a pharmaceutical composition for use in treating HTLV-1-associated myelopathy, containing a 1,3-benzodioxole derivative or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: April 26, 2022
    Assignees: DAIICHI SANKYO COMPANY, LIMITED, ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Yoshihisa Yamano, Natsumi Ueda, Kazushi Araki
  • PHARMACEUTICAL COMPOSITION USED FOR TREATMENT OF HTLV-1-ASSOCIATED MYELOPATHY
    Publication number: 20190343816
    Abstract: The present invention provides a pharmaceutical composition containing an inhibitor selected from the group consisting of an EZH1 inhibitor, an EZH2 inhibitor and an EZH1/2 dual inhibitor as an active ingredient, for use in treating HTLV-1-associated myelopathy. The present invention provides a pharmaceutical composition for use in treating HTLV-1-associated myelopathy, containing a 1,3-benzodioxole derivative or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: January 18, 2018
    Publication date: November 14, 2019
    Applicants: DAIICHI SANKYO COMPANY, LIMITED, ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Yoshihisa YAMANO, Natsumi UEDA, Kazushi ARAKI
  • Insulin resistance curative and method of screening the same
    Patent number: 7718377
    Abstract: The present invention provides a screening method for a compound which is highly safe and has a prophylactic or therapeutic effect on diabetes, and a highly safe pharmaceutical composition for the prophylaxis or treatment of diabetes. Specifically, a drug for the prophylaxis or treatment of diabetes, which contains, as an active ingredient, a compound having PPAR? activation activity and PTP inhibitory activity, and a method of screening for the drug are provided.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: May 18, 2010
    Assignee: Kyoto Pharmaceutical Industries, Ltd.
    Inventors: Kazushi Araki, Jun Ohsumi, Makoto Yachi
  • Novel Cercosporamide Derivative
    Publication number: 20090036492
    Abstract: The present invention relates to a novel cercosporamide derivative, a pharmacologically acceptable salt thereof or an ester thereof which has an excellent hypoglycemic effect and is useful as a therapeutic and/or prophylactic agent for diabetes.
    Type: Application
    Filed: August 8, 2006
    Publication date: February 5, 2009
    Inventors: Akihiro Furukawa, Jun Ohsumi, Tsuyoshi Arita, Takehiro Fukuzaki, Kazushi Araki, Makoto Mori, Takayuki Momose, Takeshi Honda, Masanori Kuroha, Ryo Okuyama, Susumu Satoh
  • Medicinal compositions containing diuretic and insulin resistance-improving agent
    Patent number: 7199139
    Abstract: The present invention relates to a pharmaceutical composition comprising an insulin sensitizer and a diuretic which can prevent or treat side effects such as edema, cardiac enlargement, body fluid retension or hydrothorax caused by administration of an insulin sensitizer.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: April 3, 2007
    Assignee: Sankyo Company, Limited
    Inventors: Masaya Takaoka, Kazushi Araki, Shoichi Kanda
  • Insulin resistance curative and method of screening the same
    Publication number: 20070059762
    Abstract: The present invention provides a screening method for a compound which is highly safe and has a prophylactic or therapeutic effect on diabetes, and a highly safe pharmaceutical composition for the prophylaxis or treatment of diabetes. Specifically, a drug for the prophylaxis or treatment of diabetes, which contains, as an active ingredient, a compound having PPAR? activation activity and PTP inhibitory activity, and a method of screening for the drug are provided.
    Type: Application
    Filed: May 28, 2004
    Publication date: March 15, 2007
    Inventors: Kazushi Araki, Jun Ohsumi, Makoto Yachi
  • Therapeutic agent for diabetes containing insulin resistance improving agent
    Publication number: 20070049515
    Abstract: A method for treating a disease, in which side effects (for example, edema) are suppressed while maintaining appropriate pharmaceutical effects. The method involves a cycle of administration of the insulin sensitizer wherein the dosage thereof is reduced or withdrawn alternated with administration of an effective dose.
    Type: Application
    Filed: September 22, 2006
    Publication date: March 1, 2007
    Applicant: SANKYO COMPANY, LIMITED
    Inventors: Shoichi Kanda, Kazushi Araki, Jun Ohsumi
  • Medicinal compositions containing diuretic and insulin resistance-improving agent
    Publication number: 20050288339
    Abstract: The present invention relates to a pharmaceutical composition comprising an insulin sensitizer and a diuretic which can prevent or treat side effects such as edema, cardiac enlargement, body fluid retension or hydrothorax caused by administration of an insulin sensitizer.
    Type: Application
    Filed: June 24, 2005
    Publication date: December 29, 2005
    Applicant: SANKYO COMPANY, LIMITED
    Inventors: Masaya Takaoka, Kazushi Araki, Shoichi Kanda
  • Medicinal compositions containing diuretic and insulin resistance-improving agent
    Publication number: 20040053974
    Abstract: The present invention relates to a pharmaceutical composition comprising an insulin sensitizer and a diuretic which can prevent or treat side effects such as edema, cardiac enlargement, body fluid retension or hydrothorax caused by administration of an insulin sensitizer.
    Type: Application
    Filed: June 26, 2003
    Publication date: March 18, 2004
    Inventors: Masaya Takaoka, Kazushi Araki, Shoichi Kanda