Patents by Inventor Kazushi Kimura

Kazushi Kimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11932787
    Abstract: A two-part curable adhesive composition includes a main agent (A) containing a urethane prepolymer (a1) and a remaining polyisocyanate (a2), and a curing agent (B) containing a non-crystalline polyol compound (b1) and a polyamine compound (b2). An equivalent ratio of an isocyanate group in a raw polyisocyanate to a hydroxyl group in the polyol compound is from 2.05 to 12. The equivalent ratio of the isocyanate group in the main agent (A) to an amino group in the polyamine compound (b2) is from 1.2 to 6. The equivalent ratio of the isocyanate group in the main agent (A) to the hydroxyl group in the non-crystalline polyol compound (b1) is from 2 to 12.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: March 19, 2024
    Assignee: The Yokohama Rubber Co., Ltd.
    Inventors: Kazushi Kimura, Hirokazu Kageyama, Yutaro Yamamoto
  • Patent number: 11896680
    Abstract: Provided is a vital stain inspection method for distinguishing between cancer cells and normal cells within a lumen, or on the serous membrane side of an organ, by means of laser irradiation after organ tissue has been stained by curcumin, Red #3 or Red #106, which are edible color dyes.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: February 13, 2024
    Assignee: MIE University
    Inventors: Akira Mizoguchi, Koji Tanaka, Kazushi Kimura, Tetsuya Nosaka, Kyosuke Tanaka, Shujie Wang, Aika Kaito, Kousyoku Sai, Yuji Toiyama, Hidemasa Goto, Masahiko Sugimoto, Yuuhei Nishimura
  • Patent number: 11852632
    Abstract: A cancer test device (1) is provided with: an application unit (40) for applying a staining agent (45), which can selectively stain a product of a cancer-relating gene in a living cell a chromatic color, onto a group of living cells; an imaging unit (10) for imaging the group of living cells having the staining agent (45) applied thereto; and a determination unit (52) for determining the level of malignancy of cancerization of the group of living cells on the basis of the state of the stained expression pattern of the cancer-relating gene in the group of living cells in an image obtained by the aforementioned imaging.
    Type: Grant
    Filed: October 12, 2022
    Date of Patent: December 26, 2023
    Assignee: Mie University
    Inventors: Akira Mizoguchi, Koji Tanaka, Naoyuki Katayama, Tetsuya Nosaka, Kyosuke Tanaka, Shujie Wang, Aika Kaito, Kousyoku Sai, Kazushi Kimura
  • Patent number: 11845866
    Abstract: The present technology provide a rubber composition including: 100 parts by mass of a diene rubber, from 30 to 100 parts by mass of carbon black and/or a white filler, from 1 to 20 parts by mass of silicone-based microparticles that have an average particle size from 5 to 500 ?m and that are three-dimensionally crosslinked, from 0.1 to 10 parts by mass of a nonionic surfactant, and from 1 to 20 parts by mass of thermally expanding microcapsules.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: December 19, 2023
    Assignee: The Yokohama Rubber Co., LTD.
    Inventors: Hirokazu Kageyama, Kazushi Kimura, Satoshi Mihara, Yutaro Yamamoto
  • Patent number: 11685190
    Abstract: A rubber composition for a tire according to an embodiment of the present technology includes: 100 parts by mass of a diene rubber and from 1 to 30 parts by mass of a thermally expandable microcapsule composite body, and the thermally expandable microcapsule composite body contains one or more thermally expandable microcapsules and an acrylonitrile butadiene copolymer and/or a crosslinked body thereof covering the one or more thermally expandable microcapsules.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: June 27, 2023
    Assignee: The Yokohama Rubber Co., Ltd.
    Inventors: Hirokazu Kageyama, Kazushi Kimura, Satoshi Mihara, Yutaro Yamamoto
  • Publication number: 20230037210
    Abstract: A cancer test device (1) is provided with: an application unit (40) for applying a staining agent (45), which can selectively stain a product of a cancer-relating gene in a living cell a chromatic color, onto a group of living cells; an imaging unit (10) for imaging the group of living cells having the staining agent (45) applied thereto; and a determination unit (52) for determining the level of malignancy of cancerization of the group of living cells on the basis of the state of the stained expression pattern of the cancer-relating gene in the group of living cells in an image obtained by the aforementioned imaging.
    Type: Application
    Filed: October 12, 2022
    Publication date: February 2, 2023
    Inventors: Akira MIZOGUCHI, Koji TANAKA, Naoyuki KATAYAMA, Tetsuya NOSAKA, Kyosuke TANAKA, Shujie WANG, Aika KAITO, Kousyoku SAI, Kazushi KIMURA
  • Patent number: 11555819
    Abstract: A cancer test device (1) is provided with: an application unit (40) for applying a staining agent (45), which can selectively stain a product of a cancer-relating gene in a living cell a chromatic color, onto a group of living cells; an imaging unit (10) for imaging the group of living cells having the staining agent (45) applied thereto; and a determination unit (52) for determining the level of malignancy of cancerization of the group of living cells on the basis of the state of the stained expression pattern of the cancer-relating gene in the group of living cells in an image obtained by the aforementioned imaging.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: January 17, 2023
    Assignee: MIE UNIVERSITY
    Inventors: Akira Mizoguchi, Koji Tanaka, Naoyuki Katayama, Tetsuya Nosaka, Kyosuke Tanaka, Shujie Wang, Aika Kaito, Kousyoku Sai, Kazushi Kimura
  • Patent number: 11413905
    Abstract: The present technology provides a tire rubber composition formed by blending a microparticle composite, which is formed from a solid component of a mixture containing an emulsion of an organic microparticle and a rubber latex, in a sulfur vulcanizable rubber; the emulsion of the organic microparticle being an emulsion containing a microparticle obtained by polymerizing and/or crosslinking at least one selected from the group consisting of polymerizable monomers, and oligomers, prepolymers, and polymers having a reactive functional group and having a molecular weight from 500 to 50000 simultaneously or stepwise in water; and an average particle size of the microparticle being from 0.001 to 100 ?m.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: August 16, 2022
    Assignee: The Yokohama Rubber Co., LTD.
    Inventors: Hirokazu Kageyama, Kazushi Kimura, Genichiro Shimada, Satoshi Mihara
  • Publication number: 20220211876
    Abstract: Provided is a method for detecting a lesion characterized by administering to an organ a cell staining agent that enables observation of biological tissue by laser irradiation, and then irradiating the organ with multiphoton laser or confocal laser to image the inside of lesion in the organ, and determining the interface between normal site and lesion site.
    Type: Application
    Filed: May 26, 2020
    Publication date: July 7, 2022
    Inventors: Akira Mizoguchi, Koji Tanaka, Kazushi Kimura, Tetsuya Nosaka, Kyosuke Tanaka, Shujie Wang, Aika Kaito, Yuji Toiyama, Hidemasa Goto, Masahiko Sugimoto, Yuuhei Nishimura, Esteban Gabazza
  • Patent number: 11293870
    Abstract: A vital stain for observation under multiphoton laser microscopy, the vital stain comprising one or more edible dye compounds.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: April 5, 2022
    Assignee: MIE UNIVERSITY
    Inventors: Akira Mizoguchi, Takeshi Fujiwara, Koji Tanaka, Shujie Wang, Kousyoku Sai, Kazushi Kimura
  • Patent number: 11279818
    Abstract: An object of the present invention is to provide a rubber composition having excellent processability, a heterocycle-modified glycerin fatty acid ester, and a production method for the heterocycle-modified glycerin fatty acid ester. The present invention includes: a rubber composition containing a rubber, silica, and a heterocycle-modified glycerin fatty acid ester, in which an epoxy group is modified with a heterocyclic compound having a heterocycle having at least one H—N< bond, where the heterocycle is at least one selected from the group consisting of a piperazine ring, a morpholine ring, and a thiomorpholine ring, and the heterocycle may have a substituent; the heterocycle-modified glycerin fatty acid ester; and a production method therefor.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: March 22, 2022
    Assignee: The Yokohama Rubber Co., Ltd.
    Inventors: Hirokazu Kageyama, Kazushi Kimura
  • Publication number: 20220056325
    Abstract: A two-part curable adhesive composition includes a main agent (A) containing a urethane prepolymer (a1) and a remaining polyisocyanate (a2), and a curing agent (B) containing a non-crystalline polyol compound (b1) and a polyamine compound (b2). An equivalent ratio of an isocyanate group in a raw polyisocyanate to a hydroxyl group in a crystalline polyol compound constituting the urethane prepolymer (a1) is from 2.05 to 12. An NCO group/total active hydrogen group ratio is from 0.5 to 4. An isocyanate group/hydroxyl group ratio is from 2 to 12.
    Type: Application
    Filed: September 27, 2019
    Publication date: February 24, 2022
    Inventors: Kazushi KIMURA, Hirokazu KAGEYAMA, Yutaro YAMAMOTO
  • Publication number: 20220033695
    Abstract: A two-part curable adhesive composition includes a main agent (A) containing a urethane prepolymer (a1) and a remaining polyisocyanate (a2), and a curing agent (B) containing a non-crystalline polyol compound (b1) and a polyamine compound (b2). An equivalent ratio of an isocyanate group in a raw polyisocyanate to a hydroxyl group in the polyol compound is from 2.05 to 12. The equivalent ratio of the isocyanate group in the main agent (A) to an amino group in the polyamine compound (b2) is from 1.2 to 6. The equivalent ratio of the isocyanate group in the main agent (A) to the hydroxyl group in the non-crystalline polyol compound (b1) is from 2 to 12.
    Type: Application
    Filed: September 27, 2019
    Publication date: February 3, 2022
    Inventors: Kazushi KIMURA, Hirokazu KAGEYAMA, Yutaro YAMAMOTO
  • Publication number: 20220033696
    Abstract: The two-part curable adhesive composition contains a main agent (A) containing a urethane prepolymer (a1) and a residual polyisocyanate (a2), and a curing agent (B) containing a polyol compound (b1) and a polyamine compound (b2). The urethane prepolymer (a1) is made by reacting in an equivalent ratio of an isocyanate group in a raw material polyisocyanate to a hydroxy group in a polycarbonate polyol being 2.05 or greater. The equivalent ratio of an isocyanate group in the main agent (A) to an active hydrogen group in the curing agent (B) is from 0.5 to 4.
    Type: Application
    Filed: September 27, 2019
    Publication date: February 3, 2022
    Inventors: Hirokazu KAGEYAMA, Kazushi KIMURA, Yutaro YAMAMOTO
  • Patent number: 11180634
    Abstract: The present invention provides a rubber composition for a tire, the rubber composition containing: a diene rubber; silica; and a heterocyclic compound (where, the heterocyclic compound does not have a silicon atom) having a hydrocarbon group having from 3 to 30 carbons and at least one type of heterocycle selected from the group consisting of a piperazine ring, a morpholine ring, and a thiomorpholine ring; an average glass transition temperature of the diene rubber being ?50° C. or higher; a content of the silica being from 80 to 200 parts by mass per 100 parts by mass of the diene rubber; and a content of the heterocyclic compound being from 0.5 to 20% by mass with respect to the content of the silica. Such rubber composition has excellent processability, exhibits excellent wet grip performance and has low rolling resistance when the rubber composition is formed into a tire.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: November 23, 2021
    Assignee: The Yokohama Rubber Co., Ltd.
    Inventors: Ayaki Kazariya, Makoto Ashiura, Satoshi Mihara, Kazushi Kimura, Hirokazu Kageyama
  • Patent number: 11180641
    Abstract: Provided is a rubber composition including: (i) a sulfur vulcanizable elastomer, (ii) carbon black and/or a white filler, and (iii) a microparticle having a three-dimensionally crosslinked structure; the microparticle being a microparticle obtained by three-dimensionally crosslinking a polymer formed from an oligomer or prepolymer that has a sulfide bond formed from two or more sulfur atoms in a main chain and/or that has a thiol group.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: November 23, 2021
    Inventors: Kazushi Kimura, Hirokazu Kageyama, Satoshi Mihara
  • Publication number: 20210347933
    Abstract: A polyurethane foam is obtained by foaming a blend containing a polyol and a polyisocyanate. The polyol contains a polycarbonate diol that has a polyester structure and a polycarbonate diol obtained by developing a polymerization reaction using 1,5-pentanediol and 1,6-hexanediol. The polyurethane foam has a density from 0.1 to 0.4 g/cm3.
    Type: Application
    Filed: September 19, 2019
    Publication date: November 11, 2021
    Inventors: Yutaro YAMAMOTO, Kazushi KIMURA, Hirokazu KAGEYAMA
  • Publication number: 20210340418
    Abstract: The two-part curable adhesive composition contains a main agent (A) containing a urethane prepolymer (a1) and a residual polyisocyanate (a2), and a curing agent (B) containing a polyol compound (b1) and a polyamine compound (b2). The urethane prepolymer (a1) is made by reacting in an equivalent ratio of an isocyanate group in a raw material polyisocyanate to a hydroxy group in a polytetramethylene ether glycol being 2.05 or greater. The equivalent ratio of an isocyanate group in the main agent (A) to an active hydrogen group in the curing agent (B) is from 0.5 to 4.
    Type: Application
    Filed: September 27, 2019
    Publication date: November 4, 2021
    Inventors: Hirokazu KAGEYAMA, Kazushi KIMURA, Yutaro YAMAMOTO
  • Patent number: 11140318
    Abstract: The present invention is provided with an imaging unit (10) that has an imaging head (11) to be inserted into the digestive tract (112) and images a living body by applying a laser to the digestive tract (112) via the imaging head (11); a control unit (50) for controlling the imaging head (11) to move inside the digestive tract (112); and an image processing unit (70) for processing an image captured by the imaging unit (10). The imaging unit (10) captures a plurality of imaging regions (P) to be imaged along with the movement of the imaging head (11) such that a portion of adjacent imaging regions (P1, P2) overlap, and the image processing unit (70) overlaps regions (Pa) in which the plurality of imaging regions (P1, P2) are overlapped to generate a composite image.
    Type: Grant
    Filed: February 23, 2017
    Date of Patent: October 5, 2021
    Assignee: Mie University
    Inventors: Akira Mizoguchi, Koji Tanaka, Yuji Toiyama, Kyosuke Tanaka, Shujie Wang, Aika Kaito, Kousyoku Sai, Kazushi Kimura
  • Publication number: 20210227133
    Abstract: The present invention is provided with an imaging unit (10) that has an imaging head (11) to be inserted into the digestive tract (112) and images a living body by applying a laser to the digestive tract (112) via the imaging head (11); a control unit (50) for controlling the imaging head (11) to move inside the digestive tract (112); and an image processing unit (70) for processing an image captured by the imaging unit (10). The imaging unit (10) captures a plurality of imaging regions (P) to be imaged along with the movement of the imaging head (11) such that a portion of adjacent imaging regions (P1, P2) overlap, and the image processing unit (70) overlaps regions (Pa) in which the plurality of imaging regions (P1, P2) are overlapped to generate a composite image.
    Type: Application
    Filed: February 23, 2017
    Publication date: July 22, 2021
    Applicant: Mie University
    Inventors: Akira MIZOGUCHI, Kiji TANAKA, Yuji TOIYAMA, Kyosuke TANAKA, Shujie WANG, Aika AITO, Kousyoku SAI, Kazushi KIMURA