Patents by Inventor Kazutoshi Fujita

Kazutoshi Fujita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11226334
    Abstract: [Problem] To provide a method for detecting high-risk prostate cancer, for the purpose of providing useful information, such as necessity of biopsy, to a test-positive patient in a PSA test. [Solution] The method for detecting high-risk prostate cancer according to the present invention comprises reacting a PSA contained in a sample composed of urine collected from a human body which is suspected to be suffering from prostate cancer with (1) a fucose ?1?6 affinitive lectin which has a characteristic property that the lectin has affinity expressed by a binding constant of 1.0×104 M?1 or more (at 25° C.) for an ?1?6 fucose sugar chain No. 405. The fucose ?1?6 affinitive lectin is preferably (2) a fucose ?1?6 specific lectin which has a characteristic property that the lectin has a binding constant of 1.0×104 M?1 or less (at 25° C.) for a sugar chain No. 003 that does not contain ?1?6 fucose and a glycolipid-type sugar chain No. 909 that does not contain ?1?6 fucose.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: January 18, 2022
    Assignees: J-CHEMICAL, INC., OSAKA UNIVERSITY
    Inventors: Yuka Kobayashi, Kazutoshi Fujita, Norio Nonomura, Eiji Miyoshi
  • Publication number: 20200264182
    Abstract: [Problem] To provide a method for detecting prostate cancer, the method having a higher degree of certainty than the PSA blood test and providing measurement values that correlate with risk classification. [Solution] This method for detecting prostate cancer is characterized in that: the method includes reacting fucose ?1?6 specific lectin and fucosylated PSA contained in a sample constituted of serum collected from a subject, and detecting the reacted lectin; and the pH in at least one step of the group consisting of the reaction step for reacting the fucosylated PSA and the lectin and processing steps thereafter is adjusted to above 8.5 and less than 11.0.
    Type: Application
    Filed: September 21, 2018
    Publication date: August 20, 2020
    Inventors: Kazutoshi FUJITA, Norio NONOMURA, Eiji MIYOSHI, Yuka KOBAYASHI
  • Publication number: 20190310258
    Abstract: Provided is a method wherein an affected tissue and a normal tissue obtained from the vicinity of the affected tissue are left at rest in a culture medium, and a disease-specific biomarker is searched for in an exudate therefrom. A biomarker specific to renal cell carcinoma has been found by this method.
    Type: Application
    Filed: October 26, 2017
    Publication date: October 10, 2019
    Applicants: JAPANESE FOUNDATION FOR CANCER RESEARCH, OSAKA UNIVERSITY
    Inventors: Koji Ueda, Naomi Ohnishi, Norio Nonomura, Motohide Uemura, Kazutoshi Fujita, Kazutake Tsujikawa, Kentarou Jingushi
  • Publication number: 20190049451
    Abstract: [Problem] To provide a method for detecting high-risk prostate cancer, for the purpose of providing useful information, such as necessity of biopsy, to a test-positive patient in a PSA test. [Solution] The method for detecting high-risk prostate cancer according to the present invention comprises reacting a PSA contained in a sample composed of urine collected from a human body which is suspected to be suffering from prostate cancer with (1) a fucose ?1?6 affinitive lectin which has a characteristic property that the lectin has affinity expressed by a binding constant of 1.0×104 M?1 or more (at 25° C.) for an ?1?6 fucose sugar chain No. 405. The fucose ?1?6 affinitive lectin is preferably (2) a fucose ?1?6 specific lectin which has a characteristic property that the lectin has a binding constant of 1.0×104 M?1 or less (at 25° C.) for a sugar chain No. 003 that does not contain ?1?6 fucose and a glycolipid-type sugar chain No. 909 that does not contain ?1?6 fucose.
    Type: Application
    Filed: February 3, 2017
    Publication date: February 14, 2019
    Applicants: J-Oil Mills, Inc., Osaka University
    Inventors: Yuka KOBAYASHI, Kazutoshi FUJITA, Norio NONOMURA, Eiji MIYOSHI
  • Publication number: 20030096882
    Abstract: The present invention is drawn to a recycled-polyester resin composition containing 100 parts by weight of a recycled polyester resin (A), 0.5 to 20 parts by weight of a lactone polymer (B), 0.5 to 30 parts by weight of an epoxidized diene-based block copolymer (C) and, optionally, 0.5 to 30 parts by weight of a polyolefin resin (D); and an article molded from the composition. The composition exhibits improved formability in terms of, for example, injection molding and extrusion molding, and the molded article has excellent mechanical strength.
    Type: Application
    Filed: August 5, 2002
    Publication date: May 22, 2003
    Inventor: Kazutoshi Fujita
  • Patent number: 3942017
    Abstract: An irradiation apparatus with high energy electrons is disclosed in which a wire shaped or linear object to be irradiated is moved back and forth many times under an electron window so as to irradiate it with an electron beam. According to one feature of the invention, an electron beam, which leaks through gaps between the objects to be irradiated or which penetrates the objects to be irradiated, is reversed by a magnetic field approximately perpendicular to the scanning face of the electron beam by means of a magnet which is disposed under the objects to be irradiated, and the reversed electron beam is thereby again applied to the objects to be irradiated. A high utilization rate of the electron beam is accomplished, and the objects can be thereby uniformly irradiated with the electron beam.
    Type: Grant
    Filed: September 9, 1974
    Date of Patent: March 2, 1976
    Assignee: Sumitomo Electric Industries, Ltd.
    Inventors: Kenichiro Uehara, Atsuo Ito, Koichi Nishimune, Kazutoshi Fujita