Patents by Inventor Kazutoshi Haraguchi
Kazutoshi Haraguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230302203Abstract: An implant capable of maintaining, even when being implanted in a body for a long period of time, desirable mechanical properties, non-bioabsorbable properties, and/or biocompatibility is provided. The implant contains a nanocomposite hydrogel obtained through formation of an organic-inorganic network structure in which an amide group-containing polymer compound and an inorganic clay nano-sheet are linked.Type: ApplicationFiled: July 30, 2021Publication date: September 28, 2023Inventors: Samuel JK ABRAHAM, Kazutoshi HARAGUCHI
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Publication number: 20190381469Abstract: A temperature-responsive hydrogel exhibiting a high viscosity at a high temperature, a low viscosity at a low temperature and a high ratio of the viscosity at a high temperature to the viscosity at a low temperature produced by mixing of an aqueous solution containing a polyalkylene glycol having an average molecular weight of 20,000 to 10,000,000 with an aqueous dispersion containing a silicate salt so as to achieve a specific compositional range of the components in the hydrogel, at a mass concentration of A of 0.01 to 1.5% by mass, at a mass concentration of A of 0.1 to 0.4% by mass and at a mass concentration of B of 0.5 to 10% by mass, at a mass concentration of B of 1 to 5% by mass, with the mass ratio R of A to B (R=(mass of A)/(mass of B)) within the range of 0.01 to 0.5.Type: ApplicationFiled: March 2, 2018Publication date: December 19, 2019Applicants: Nissan Chemical Corporation, NIHON UNIVERSITYInventors: Yoshihiro KUDO, Kazutoshi HARAGUCHI
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Patent number: 10030113Abstract: The invention provides a gas barrier film with low deterioration in the gas barrier property before and after high-temperature hot water treatment. The gas barrier film has a gas barrier coating film, formed as a composite film comprising a network structure having a mesh structure with Si—O—Si bonds as the basic lattice and a water-soluble polymer crystallized as microcrystals, incorporated into the mesh of the network structure, wherein a barrier coating agent, obtained by mixing a condensate solution of an alkoxysilane hydrolysate prepared as a mixed solution in which the proportion of bonded states of the silicon atoms of the condensate with Q1 and Q2 structures is at least 60% of the total silicon atoms, with a crystalline water-soluble polymer, is coated on a base material film, either after forming or without forming an aluminum oxide vapor deposition film, to form a coating layer.Type: GrantFiled: March 27, 2015Date of Patent: July 24, 2018Assignee: Dai Nippon Printing Co., Ltd.Inventors: Azusa Suzuki, Hiroyuki Iwahashi, Takeshi Nishizono, Shigeki Matsui, Kazutoshi Haraguchi
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Publication number: 20170009034Abstract: The invention provides a gas barrier film with low deterioration in the gas barrier property before and after high-temperature hot water treatment. The gas barrier film has a gas barrier coating film, formed as a composite film comprising a network structure having a mesh structure with Si—O—Si bonds as the basic lattice and a water-soluble polymer crystallized as microcrystals, incorporated into the mesh of the network structure, wherein a barrier coating agent, obtained by mixing a condensate solution of an alkoxysilane hydrolysate prepared as a mixed solution in which the proportion of bonded states of the silicon atoms of the condensate with Q1 and Q2 structures is at least 60% of the total silicon atoms, with a crystalline water-soluble polymer, is coated on a base material film, either after forming or without forming an aluminum oxide vapor deposition film, to form a coating layer.Type: ApplicationFiled: March 27, 2015Publication date: January 12, 2017Inventors: Azusa SUZUKI, Hiroyuki IWAHASHI, Kenji NISHIZONO, Shigeki MATSUI, Kazutoshi HARAGUCHI
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Patent number: 9474835Abstract: The object of the present invention is achieved by providing a copolymer, in particular, a block copolymer which has excellent coating formation ability, adhesive properties to a substrate, and does not adsorb protein; an antithrombotic coating agent which has superior antithrombotic properties and adhesive properties to a substrate to those of the conventional antithrombotic coating agent; and a medical instrument which is obtained by coating the antithrombotic coating agent, and the block copolymer includes a polymer (A) containing a (meth)acrylic ester monomer and a polymer (B) containing a (meth)acrylamide monomer and has excellent coating formation ability and high adhesive properties to a substrate.Type: GrantFiled: August 10, 2012Date of Patent: October 25, 2016Assignees: Kawamura Institute of Chemical Research, DIC CorporationInventors: Kazutoshi Haraguchi, Kazuomi Kubota, Tooru Takehisa, Tetsuo Takada, Noriko Santou
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Patent number: 9382401Abstract: The problem to be solved is to provide a nondrying polymer hydrogel, which is not dried under atmospheric conditions and has excellent mechanical properties, and a method for producing the nondrying polymer hydrogel. A nondrying polymer hydrogel having both excellent nondrying properties and mechanical properties (e.g., excellent elongation properties, compression properties, and surface adhesiveness) can be produced by using a nondrying polymer hydrogel including a deliquescent substance in such a manner that the water vapor pressure shown by the polymer hydrogel is equal to or lower than the water vapor partial pressure in the atmosphere, in particular, by allowing a deliquescent substance to be contained at a high concentration in a polymer hydrogel having a network structure formed by a polymer of a water-soluble radically-polymerizable organic monomer having a specific chemical composition and a delaminated water-swellable clay mineral.Type: GrantFiled: June 19, 2013Date of Patent: July 5, 2016Assignees: DIC Corporation, Kawamura Institute of Chemical ResearchInventors: Kazutoshi Haraguchi, Katsuhito Kuroki
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Publication number: 20140343209Abstract: The problem to be solved is to provide a nondrying polymer hydrogel, which is not dried under atmospheric conditions and has excellent mechanical properties, and a method for producing the nondrying polymer hydrogel. A nondrying polymer hydrogel having both excellent nondrying properties and mechanical properties (e.g., excellent elongation properties, compression properties, and surface adhesiveness) can be produced by using a nondrying polymer hydrogel including a deliquescent substance in such a manner that the water vapor pressure shown by the polymer hydrogel is equal to or lower than the water vapor partial pressure in the atmosphere, in particular, by allowing a deliquescent substance to be contained at a high concentration in a polymer hydrogel having a network structure formed by a polymer of a water-soluble radically-polymerizable organic monomer having a specific chemical composition and a delaminated water-swellable clay mineral.Type: ApplicationFiled: June 19, 2013Publication date: November 20, 2014Applicants: KAWAMURA INSTITUTE OF CHEMICAL RESEARCH, DIC CorporationInventors: Kazutoshi Haraguchi, Katsuhito Kuroki
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Publication number: 20140235748Abstract: The object of the present invention is achieved by providing a copolymer, in particular, a block copolymer which has excellent coating formation ability, adhesive properties to a substrate, and does not adsorb protein; an antithrombotic coating agent which has superior antithrombotic properties and adhesive properties to a substrate to those of the conventional antithrombotic coating agent; and a medical instrument which is obtained by coating the antithrombotic coating agent, and the block copolymer includes a polymer (A) containing a (meth)acrylic ester monomer and a polymer (B) containing a (meth)acrylamide monomer and has excellent coating formation ability and high adhesive properties to a substrate.Type: ApplicationFiled: August 10, 2012Publication date: August 21, 2014Applicants: DIC CORPORATION, KAWAMURA INSTITUTE OF CHEMICAL RESEARCHInventors: Kazutoshi Haraguchi, Kazuomi Kubota, Tooru Takehisa, Tetsuo Takada, Noriko Santou
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Patent number: 8530564Abstract: Disclosed are: an organic-inorganic complex dispersion improved in film formability and adhesion to a base material. The organic-inorganic complex dispersion comprises an aqueous medium and particles of a complex dispersed in the aqueous medium, wherein the complex has a three-dimensional network structure formed by a polymer of a monomer comprising a monomer represented by general formula (1) and at least one inorganic material selected from a water-swellable clay mineral and silica. Also disclosed is an antifogging material manufactured by using the organic-inorganic complex dispersion. Further disclosed is a cell culture substratum improved in the detachability of cells cultured on the substratum, which is manufactured by using the organic-inorganic complex dispersion. Still further disclosed are manufacturing methods for same.Type: GrantFiled: May 25, 2009Date of Patent: September 10, 2013Assignees: Kawamura Institute of Chemical Research, DIC CorporationInventors: Tetsuo Takada, Kazutoshi Haraguchi
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Publication number: 20120071808Abstract: A patch material which includes a backing material having a water-vapor permeability of 3,000 g/m2·day or more and an adhesive layer having a water-vapor permeability of 5,000 g/m2·day or more, wherein the adhesive layer comprises a polyurethane adhesive obtained by reacting (i) an active hydrogen compound having a number-average molecular weight of 5,000 or more and an average number of functional groups of 2 or more, and having a polyoxyalkylene structure, (ii) an active hydrogen compound having a number-average molecular weight of 1,500 to 5,000 and an average number of functional groups of 1, and having a polyoxyalkylene structure, and (iii) an organic polyisocyanate, wherein an average number of functional groups of all active hydrogen compounds used for obtaining the adhesive is 2 to 2.6, and the content of ethylene oxide units of all active hydrogen compounds in the adhesive is 3 to 8% by weight.Type: ApplicationFiled: May 28, 2010Publication date: March 22, 2012Inventors: Eisaku Sato, Ryuji Saito, Kazutoshi Haraguchi, Yoshiko Koike, Tomonori Ikai
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Patent number: 7993892Abstract: The present invention provides a production process of an organic/inorganic composite hydrogel, which demonstrates superior mechanical properties, by uniformly dispersing a clay mineral in an organic polymer over a wide range of clay mineral content, and a dried form thereof, to be produced easily in a short period of time. The production process of an organic/inorganic composite hydrogel of the present invention comprises reacting a water-soluble organic monomer (a) in the presence of a water-swellable clay mineral (b) by irradiating with an energy beam in a solution in which a non-water-soluble polymerization initiator (d) is dispersed in an aqueous medium (c).Type: GrantFiled: December 13, 2005Date of Patent: August 9, 2011Assignee: Kawamura Institute of Chemical ResearchInventors: Tetsuo Takada, Kazutoshi Haraguchi, Tooru Takehisa
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Publication number: 20110097802Abstract: Disclosed are: an organic-inorganic complex dispersion improved in film formability and adhesion to a base material. The organic-inorganic complex dispersion comprises an aqueous medium and particles of a complex dispersed in the aqueous medium, wherein the complex has a three-dimensional network structure formed by a polymer of a monomer comprising a monomer represented by general formula (1) and at least one inorganic material selected from a water-swellable clay mineral and silica. Also disclosed is an antifogging material manufactured by using the organic-inorganic complex dispersion. Further disclosed is a cell culture substratum improved in the detachability of cells cultured on the substratum, which is manufactured by using the organic-inorganic complex dispersion. Still further disclosed are manufacturing methods for same.Type: ApplicationFiled: May 25, 2009Publication date: April 28, 2011Applicants: Kawamura Institute of Chemical Research, DIC CorporationInventors: Tetsuo Takada, Kazutoshi Haraguchi
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Publication number: 20090291500Abstract: The present invention provides a production process of an organic/inorganic composite hydrogel, which demonstrates superior mechanical properties, by uniformly dispersing a clay mineral in an organic polymer over a wide range of clay mineral content, and a dried form thereof, to be produced easily in a short period of time. The production process of an organic/inorganic composite hydrogel of the present invention comprises reacting a water-soluble organic monomer (a) in the presence of a water-swellable clay mineral (b) by irradiating with an energy beam in a solution in which a non-water-soluble polymerization initiator (d) is dispersed in an aqueous medium (c).Type: ApplicationFiled: December 13, 2005Publication date: November 26, 2009Applicant: KAWAMURA INSTITUTE OF CHEMICAL RESEARCHInventors: Tetsuo Takada, Kazutoshi Haraguchi, Tooru Takehisa
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Patent number: 7378461Abstract: The invention relates to (1) a curable epoxy resin composition comprising (A) a non-gel type amine-modified epoxy resin which is obtained by reacting an epoxy resin with a polyamine and (B) at least one of boric acid and boric ester, (2) a powder form of the curable epoxy resin composition and a process for its production, and (3) a process for production of heat-resistant laminated sheets by using the curable epoxy resin composition. The invention provides (1) a curable epoxy resin composition capable of giving a cured article having a high glass transition temperature and excellent mechanical properties, (2) a powder form of curable epoxy resin composition having a high glass transition temperature, excellent mechanical properties and excellent storage stability and a process for its production, and (3) heat-resistant laminated sheets made by using the curable epoxy resin compositions and having excellent heat resistance and mechanical properties.Type: GrantFiled: October 31, 2002Date of Patent: May 27, 2008Assignee: Kawamura Institute of Chemical ResearchInventors: Kazutoshi Haraguchi, Akira Ohbayashi
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Patent number: 7365120Abstract: A polymer composite and a stretched product thereof formed from a three dimensional network structure including an organic polymer (A), comprising either a polymer produced from a water soluble (meth)acrylate ester (a), or a copolymer of a water soluble (meth)acrylate ester (a) and at least one compound selected from a group consisting of (meth)acrylamide and N-substituted (meth)acrylamides (b), and a water swelling clay mineral (B).Type: GrantFiled: April 16, 2004Date of Patent: April 29, 2008Assignee: Kawamura Institute of Chemical ResearchInventors: Kazutoshi Haraguchi, Toru Takehisa, Makiko Ebato
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Publication number: 20060247334Abstract: An epoxy resin composition comprising, as essential components, an epoxy resin having two or more epoxy groups in the molecule, and a polyamine borate as a curing agent for the epoxy resin, whrein the polyamine borate is obtained from a polyamine-based compound (A) having at least one of amino group and imino group in the molecule and a boric acid-based compound (B) represented by the following general formula (1): B(OR)n(OH)3-n ??(1) wherein n represents an integer of 0 to 3, R represents an alkyl group represented by CmH2m+1, and m represents an integer of 1 to 10.Type: ApplicationFiled: August 4, 2004Publication date: November 2, 2006Inventors: Akira Ohbayashi, Kazutoshi Haraguchi
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Publication number: 20060148958Abstract: The polymer gel obtained from the method for incorporating hydroxyapatite in a polymer hydrogel by impregnating an aqueous phosphoric acid alkali metal salt solution and an aqueous carbonate solution alternately one or more times with a polymer gel consisting of a polymer of a water-soluble organic monomer and a water-swelling clay mineral, contains finely dispersed biocompatible substances, and the polymer gel excels in dynamic physical property and stability and can exhibit the performance of the biocompatible substance efficiently. The dried biocompatible substance-containing polymer gel is obtained by drying the above polymer gel.Type: ApplicationFiled: January 7, 2004Publication date: July 6, 2006Applicant: Kawamura Institute of Chemical ResearchInventors: Kazutoshi Haraguchi, Tooru Takehisa
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Publication number: 20050234179Abstract: A polymer composite and a stretched product thereof formed from a three dimensional network structure including an organic polymer (A), comprising either a polymer produced from a water soluble (meth)acrylate ester (a), or a copolymer of a water soluble (meth)acrylate ester (a) and at least one compound selected from a group consisting of (meth)acrylamide and N-substituted (meth)acrylamides (b), and a water swelling clay mineral (B).Type: ApplicationFiled: April 16, 2004Publication date: October 20, 2005Applicant: KAWAMURA INSTITUTE OF CHEMICAL RESEARCH.Inventors: Kazutoshi Haraguchi, Toru Takehisa, Makiko Ebato
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Patent number: 6943206Abstract: The present invention provides a novel organic/inorganic hybrid hydrogel which is superior in homogeneity, transparency, mechanical properties, and in swelling and shrinking properties, a manufacturing method therefor, and a dry body of the organic/inorganic hybrid hydrogel which is obtained by removing water from said hydrogel. The organic/inorganic hybrid hydrogel comprises a water soluble polymer (A), a water swelling clay mineral (B) which can be homogeneously dispersed in water, and water (C), and water (C) is included in a three-dimensional network formed by (A) and (B).Type: GrantFiled: November 17, 2003Date of Patent: September 13, 2005Assignee: Kawamura Institute of Chemical ResearchInventor: Kazutoshi Haraguchi
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Publication number: 20040254328Abstract: The invention relates to (1) a curable epoxy resin composition comprising (A) a non-gel type amine-modified epoxy resin which is obtained by reacting an epoxy resin with a polyamine and (B) at least one of boric acid and boric ester, (2) a powder form of the curable epoxy resin composition and a process for its production, and (3) a process for production of heat-resistant laminated sheets by using the curable epoxy resin composition. The invention provides (1) a curable epoxy resin composition capable of giving a cured article having a high glass transition temperature and excellent mechanical properties, (2) a powder form of curable epoxy resin composition having a high glass transition temperature, excellent mechanical properties and excellent storage stability and a process for its production, and (3) heat-resistant laminated sheets made by using the curable epoxy resin compositions and having excellent heat resistance and mechanical properties.Type: ApplicationFiled: April 20, 2004Publication date: December 16, 2004Inventors: Kazutoshi Haraguchi, Akira Ohbayashi