Patents by Inventor Kazutoshi Yanagibashi

Kazutoshi Yanagibashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridocarbazole derivatives having cgmp-pde inhibitory activity
    Patent number: 6197768
    Abstract: The invention relates to novel pyridocarbazole derivatives having highly selective action in inhibiting cyclic GMP-phosphodiesterase (hereinafter abbreviated as cGMP-PDE), processes for producing such derivatives, agents containing at least one of such derivatives as an active ingredient for preventing and/or treating pulmonary hypertension, ischemic heart diseases or diseases against which the cGMP-PDE inhibitory action is effective, and intermediates useful for the production of pyridocarbazole derivatives.
    Type: Grant
    Filed: September 10, 1999
    Date of Patent: March 6, 2001
    Assignee: Mochida Pharmaceutical Co., Ltd.
    Inventors: Masayuki Ohashi, Toshiyuki Shudo, Kazumi Nishijima, Tatsuto Notsu, Akira Kikuchi, Kazutoshi Yanagibashi, Hidemitsu Nishida
  • Pyridocarbazole derivatives having cGMP-PDE inhibitory activity
    Patent number: 6018046
    Abstract: The invention relates to novel pyridocarbazole derivatives having highly selective action in inhibiting cyclic GMP-phosphodiesterase (hereinafter abbreviated as cGMP-PDE), processes for producing such derivatives, agents containing at least one of such derivatives as an active ingredient for preventing and/or treating pulmonary hypertension, ischemic heart diseases or diseases against which the cGMP-PDE inhibitory action is effective, and intermediates useful for the production of pyridocarbazole derivatives.
    Type: Grant
    Filed: January 29, 1998
    Date of Patent: January 25, 2000
    Assignee: Mochida Pharmaceutical Co., Ltd.
    Inventors: Masayuki Ohashi, Toshiyuki Shudo, Kazumi Nishijima, Tatsuto Notso, Akira Kikuchi, Kazutoshi Yanagibashi, Hidemitsu Nishida
  • Pyrimidine derivatives
    Patent number: 5397781
    Abstract: The present invention relates to novel 5-(.omega.-substituted amino-alkanoyl amino)pyrimidine derivatives, processes for producing the derivatives, and pharmaceutical compositions containing said derivatives. The compounds in the present invention have potent effects of inhibiting ACAT activity and lowering serum cholesterol. The compounds of the present invention are extremely useful for the treatment and/or prevention of arteriosclerosis or hyperlipidemia.
    Type: Grant
    Filed: February 11, 1993
    Date of Patent: March 14, 1995
    Assignee: Mochida Pharmaceutical Company, Limited
    Inventors: Kazutoshi Yanagibashi, Kiyoshi Mizuguchi, Shuhei Ohnishi, Kimihiro Murakami