Patents by Inventor Kazuyasu Asami

Kazuyasu Asami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing aminothiazole derivative and production intermediate
    Patent number: 9000163
    Abstract: Provided is a method for selectively demethylating a 2-methoxy group. Specifically provided is a production method of a compound represented by formula (7) below through the following reactions.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: April 7, 2015
    Assignee: Zeria Pharmaceutical Co., Ltd.
    Inventors: Masaaki Nagasawa, Kazuyasu Asami, Ryu Nakao, Nobuyuki Tanaka, Yoshiyuki Aida
  • Method for producing aminothiazole derivative and production intermediate
    Patent number: 8841461
    Abstract: Provided is a method for selectively demethylating a 2-methoxy group. Specifically provided is a production method of a compound represented by formula (7) below through the following reactions.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: September 23, 2014
    Assignee: Zeria Pharmaceutical Co., Ltd.
    Inventors: Masaaki Nagasawa, Kazuyasu Asami, Ryu Nakao, Nobuyuki Tanaka, Yoshiyuki Aida
  • Method for producing aminothiazole derivative and production intermediate
    Patent number: 8772528
    Abstract: Provided is a method for selectively demethylating a 2-methoxy group. Specifically provided is a production method of a compound represented by formula (7) below through the following reactions.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: July 8, 2014
    Assignee: Zeria Pharmaceutical Co., Ltd.
    Inventors: Masaaki Nagasawa, Kazuyasu Asami, Ryu Nakao, Nobuyuki Tanaka, Yoshiyuki Aida
  • METHOD FOR PRODUCING AMINOTHIAZOLE DERIVATIVE AND PRODUCTION INTERMEDIATE
    Publication number: 20140058104
    Abstract: Provided is a method for selectively demethylating a 2-methoxy group. Specifically provided is a production method of a compound represented by formula (7) below through the following reactions.
    Type: Application
    Filed: October 29, 2013
    Publication date: February 27, 2014
    Applicant: ZERIA PHARMACEUTICAL CO., LTD.
    Inventors: Masaaki NAGASAWA, Kazuyasu Asami, Ryu Nakao, Nobuyuki Tanaka, Yoshiyuki Aida
  • METHOD FOR PRODUCING AMINOTHIAZOLE DERIVATIVE AND PRODUCTION INTERMEDIATE
    Publication number: 20140058112
    Abstract: Provided is a method for selectively demethylating a 2-methoxy group. Specifically provided is a production method of a compound represented by formula (7) below through the following reactions.
    Type: Application
    Filed: October 29, 2013
    Publication date: February 27, 2014
    Applicant: ZERIA PHARMACEUTICAL CO., LTD.
    Inventors: Masaaki NAGASAWA, Kazuyasu Asami, Ryu Nakao, Nobuyuki Tanaka, Yoshiyuki Aida
  • METHOD FOR PRODUCING AMINOTHIAZOLE DERIVATIVE AND PRODUCTION INTERMEDIATE
    Publication number: 20140046088
    Abstract: Provided is a method for selectively demethylating a 2-methoxy group. Specifically provided is a production method of a compound represented by formula (7) below through the following reactions.
    Type: Application
    Filed: October 29, 2013
    Publication date: February 13, 2014
    Applicant: ZERIA PHARMACEUTICAL CO., LTD.
    Inventors: Masaaki NAGASAWA, Kazuyasu Asami, Ryu Nakao, Nobuyuki Tanaka, Yoshiyuki Aida
  • Method for producing aminothiazole derivative and production intermediate
    Patent number: 8586761
    Abstract: Provided is a method for selectively demethylating a 2-methoxy group. Specifically provided is a production method of a compound represented by formula (7) below through the following reactions.
    Type: Grant
    Filed: August 23, 2005
    Date of Patent: November 19, 2013
    Assignee: Zeria Pharmaceutical Co., Ltd.
    Inventors: Masaaki Nagasawa, Kazuyasu Asami, Ryu Nakao, Nobuyuki Tanaka, Yoshiyuki Aida
  • Method For Producing Aminothiazole Derivative And Production Intermediate
    Publication number: 20080021221
    Abstract: Provided is a method for selectively demethylating a 2-methoxy group.
    Type: Application
    Filed: August 23, 2005
    Publication date: January 24, 2008
    Applicant: ZERIA PHARMACEUTICAL CO., LTD. , a corporation
    Inventors: Masaaki Nagasawa, Kazuyasu Asami, Ryu Nakao, Nobuyuki Tanaka, Yoshiyuki Aida
  • 1-N-Aminobenzimidazole derivatives
    Publication number: 20050148634
    Abstract: Provided are 1-N-aminobenzimidazole derivatives represented by the following formula (I): wherein R1 and R2 each represents a substituted or unsubstituted alkyl group or the like, R3, R5 and R6 each represents an alkyl group, alkoxy group, hydrogen atom or the like, R4 represents a substituted or unsubstituted alkyl group or the like, A represents a benzene ring or the like, B represents a hydrogen atom or the like, an n stands for an integer of from 0 to 2, or salts thereof; and medicines containing them. The compounds (I) according to the present invention do not bring about much individual differences in therapeutic effects despite the existence of individual differences in the CYP2C19 activity. At the same dose, they can hence bring about appropriate therapeutic effects for all patients. In addition, they are low in the risk of induction of an interaction or a cancer caused by induction of the CYP1A family.
    Type: Application
    Filed: March 28, 2003
    Publication date: July 7, 2005
    Applicant: ZERIA PHARMACEUTICAL CO., LTD
    Inventors: Masaaki Nagasawa, Hiroyasu Nishioka, Kazuyasu Asami, Naoyoshi Miura, Hideki Nakamura, Hitoshi Morita
  • Benzimidazole derivatives
    Patent number: 6884810
    Abstract: A benzimidazole derivative of formula (1): (wherein R represents a hydrogen atom or a methoxy group, and n is 0 or 1) or a salt thereof; and a medicament containing the same. The compounds of the present invention, due to minimized difference in therapeutic effect between subjects, which difference would otherwise be derived from different CYP2C19 activity from subject to subject, ensure that all patients can enjoy proper therapeutic effects at the same dose of the drug. Also, the compounds of the invention have low risk of drug interaction caused by induction of CYP1A family member enzymes, as well as low risk of development of cancer, and thus is useful as a remedy for peptic ulcer, reliably providing therapeutic effects with safety.
    Type: Grant
    Filed: September 18, 2002
    Date of Patent: April 26, 2005
    Assignee: Zeria Pharmaceutical Co., Ltd.
    Inventors: Masaaki Nagasawa, Hiroyasu Nishioka, Kazuyasu Asami, Naoyoshi Miura, Yutaka Shinozaki, Hitoshi Morita
  • Benzimidazole derivatives
    Publication number: 20030236411
    Abstract: A benzimidazole derivative of formula (1): 1
    Type: Application
    Filed: March 17, 2003
    Publication date: December 25, 2003
    Inventors: Masaaki Nagasawa, Hiroyasu Nishioka, Kazuyasu Asami, Naoyoshi Miura, Yutaka Shinozaki, Hitoshi Morita