Patents by Inventor Kazuyuki Ishii
Kazuyuki Ishii has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240078988Abstract: A musical instrument includes: a fixed member; a movable member displaceable relative to the fixed member within a movable range in response to a playing operation of the musical instrument; a detectable circuit including a magnetic or conductive body and disposed on the movable member; a detector circuit including a coil disposed on the fixed member and configured to output a detection signal corresponding to a voltage that is dependent on a distance between the detectable circuit and the coil; at least one memory storing instructions; and at least one processor configured to implement the instructions to perform a plurality of tasks, including: a generating task that generates, based on correspondences between voltages of detection signals and positions of the movable member in the movable range, position data indicating a position of the movable member that depends on the voltage of the detection signal output from the detector circuit; and a calibrating task that calibrates the correspondences based on thType: ApplicationFiled: November 7, 2023Publication date: March 7, 2024Inventors: Jun ISHII, Kazuyuki IGARASHI, Akihiko KOMATSU, Michiko TANOUE
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Publication number: 20240071344Abstract: A musical instrument includes a fixed member; a movable member displaceable in response to a playing operation of the musical instrument, the movable member being displaceable relative to the fixed member from a first state where the movable member is in an initial position to a second state where the movable member is displaced from the initial position; a detectable circuit including a magnetic or conductive body and disposed on the movable member; and a detector circuit including a coil disposed on the fixed member and configured to output a detection signal corresponding to a voltage that is dependent on a distance between the detectable circuit and the coil. A distance between the detectable circuit and the coil in the first state is smaller than a distance between the detectable circuit and the coil in the second state.Type: ApplicationFiled: November 7, 2023Publication date: February 29, 2024Inventors: Jun ISHII, Kazuyuki IGARASHI
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Publication number: 20230143744Abstract: The present invention is to provide a novel adsorbent which is low in cost, has versatility and has high adsorption ability. Specifically, the present invention is to provide an adsorbent containing a metal salt of a cyanometallic acid obtained by a reaction of a salt of a cyanometallic acid and a compound containing a metal element, wherein the reaction is carried out using the compound containing a metal element in an amount of less than 100 mol % of the theoretical amount relative to 1 mol of the salt of a cyanometallic acid, a method of producing the same, and a method for removing harmful ions from water using such an adsorbent.Type: ApplicationFiled: January 20, 2021Publication date: May 11, 2023Applicant: THE UNIVERSITY OF TOKYOInventors: Kazuyuki ISHII, Kyoko ENOMOTO
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Publication number: 20230071223Abstract: The present invention is to provide a novel adsorbent which is low in cost, has versatility and high adsorption ability. Specifically, the present invention is to provide an adsorbent of a specific metal element containing a metal salt of a cyanometallic acid, a method for producing the same, and a method for removing the ion of the element that is the target of adsorption using such an adsorbent.Type: ApplicationFiled: January 20, 2021Publication date: March 9, 2023Applicant: THE UNIVERSITY OF TOKYOInventors: Kazuyuki ISHII, Kyoko ENOMOTO
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Patent number: 9938039Abstract: A box includes a front receiving panel, a bottom surface panel, a rear surface panel, a top surface panel, and a front surface panel that are integrally connected one to another. Each pair of bottom side panels, rear side panels, top side panels, and front side panels are integrally connected to the respective sides of each of the bottom, rear, top, and front surface panels. The front receiving panel, the bottom and rear surface panels, and the bottom and rear side panels constitute a tray portion of the box, with the remaining panels constituting a lid portion of the box. A cut line for separating the lid portion from the tray portion is formed to pass through one or both of the rear surface panel and the top surface panel.Type: GrantFiled: September 30, 2014Date of Patent: April 10, 2018Assignee: Rengo Co., Ltd.Inventors: Yoichi Nishikawa, Atsuo Ishikawa, Takafumi Makiuchi, Akira Nagaosa, Masayuki Handa, Masanori Yoshida, Hiroyuki Noguchi, Hiromu Ikeda, Kazuyuki Ishii, Hironori Sugita, Tatsuya Fujibayashi
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Patent number: 9937264Abstract: [Problem] To provide a glycosylated polypeptide having an affinity to somatostatin receptors, and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least one amino acid in a somatostatin or an analog thereof being replaced with a glycosylated amino acid.Type: GrantFiled: July 8, 2016Date of Patent: April 10, 2018Assignee: GLYTECH, INC.Inventors: Hirofumi Ochiai, Taiji Shimoda, Kazuhiro Fukae, Masatoshi Maeda, Kazuyuki Ishii, Kenta Yoshida, Katsunari Tezuka, Keisuke Tazuru
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Publication number: 20170157260Abstract: [Problem] To provide a glycosylated polypeptide having an affinity to somatostatin receptors, and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least one amino acid in a somatostatin or an analogue thereof being replaced with a glycosylated amino acid.Type: ApplicationFiled: July 8, 2016Publication date: June 8, 2017Inventors: Hirofumi Ochiai, Taiji Shimoda, Kazuhiro Fukae, Masatoshi Maeda, Kazuyuki Ishii, Kenta Yoshida, Katsunari Tezuka, Keisuke Tazuru
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Patent number: 9511098Abstract: A method for producing dry earthworm powder, by which dry earthworm powder having high-titer enzymes can be produced while removing toxic substances contained in the bodies of earthworms, is provided. The method comprises: contacting a live earthworm with a chloride(s) of at least one metal selected from the group consisting of potassium, sodium, magnesium and calcium; and subsequently contacting the live earthworm with powder of a hydroxycarboxylic acid(s) and diluting the resulting mixture with water to adjust pH to 2 to 5, followed by leaving the live earthworm to stand for 3 to 180 minutes, washing the live earthworm with water, grinding the washed live earthworm and freeze-drying the obtained ground product.Type: GrantFiled: October 5, 2011Date of Patent: December 6, 2016Assignee: WELL STONE CO.Inventor: Kazuyuki Ishii
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Publication number: 20160304236Abstract: A box includes a front receiving panel, a bottom surface panel, a rear surface panel, a top surface panel, and a front surface panel that are integrally connected one to another. Each pair of bottom side panels, rear side panels, top side panels, and front side panels are integrally connected to the respective sides of each of the bottom, rear, top, and front surface panels. The front receiving panel, the bottom and rear surface panels, and the bottom and rear side panels constitute a tray portion of the box, with the remaining panels constituting a lid portion of the box. A cut line for separating the lid portion from the tray portion is formed to pass through one or both of the rear surface panel and the top surface panel.Type: ApplicationFiled: September 30, 2014Publication date: October 20, 2016Applicant: RENGO CO., LTD.Inventors: Yoichi NISHIKAWA, Atsuo ISHIKAWA, Takafumi MAKIUCHI, Akira NAGAOSA, Masayuki HANDA, Masanori YOSHIDA, Hiroyuki NOGUCHI, Hiromu IKEDA, Kazuyuki ISHII, Hironori SUGITA, Tatsuya FUJIBAYASHI
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Patent number: 9455054Abstract: The present invention relates to a radioactive cesium adsorbent, a method for producing the same, and a method for decontaminating the environment from radioactive cesium with the adsorbent. The radioactive cesium adsorbent of the present invention includes a hydrophilic fiber substrate supporting a Prussian blue analog, in particular, Prussian blue, and the Prussian blue analog is immobilized in the inside of the fibers.Type: GrantFiled: August 16, 2012Date of Patent: September 27, 2016Assignee: The Foundation for the Promotion of Industrial ScienceInventors: Kazuyuki Ishii, Masashi Obi, Kazuaki Kudo, Kengo Akagawa, Tetsu Tatsuma, Akiyoshi Sakoda
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Patent number: 9422357Abstract: [Problem] To provide a glycosylated polypeptide having an affinity to somatostatin receptors, and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least one amino acid in a somatostatin or an analog thereof being replaced with a glycosylated amino acid.Type: GrantFiled: September 3, 2012Date of Patent: August 23, 2016Assignee: Glytech, Inc.Inventors: Hirofumi Ochiai, Taiji Shimoda, Kazuhiro Fukae, Masatoshi Maeda, Kazuyuki Ishii, Kenta Yoshida, Katsunari Tezuka, Keisuke Tazuru
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Patent number: 9127041Abstract: A process for chemically converting a peptide chain into a peptide thioester includes, when a —C(?X)—R1 group is introduced to the thiol group of the cysteine residue and then the resulting peptide is reacted with a compound having a leaving group represented by the formula: —NH—C(?Y)NHR3 in an organic solvent, the —NH—C(?Y)NHR3 group binds via addition reaction to the carboxyl group of the N-terminal-side peptide bond of the cysteine residue, whereby the peptide bond is cleaved and the C-terminal-side peptide fragment is cut off. Further, when the resulting peptide chain having the —NH—C(?Y)NHR3 group is reacted with a thiol in a buffer solution, a thiol exchange reaction occurs, namely, the thiol group of the thiol binds to the carbonyl carbon to which the —NH—C(?Y)NHR3 group has bound, whereby the —NH—C(?Y)NHR3 group is eliminated.Type: GrantFiled: January 23, 2014Date of Patent: September 8, 2015Assignee: Glytech, Inc.Inventors: Yasuhiro Kajihara, Ryo Okamoto, Izumi Sakamoto, Kazuyuki Ishii
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Patent number: 9073978Abstract: [Technical Problem] To provide a method for manufacturing that enables to obtain a targeted glycopeptide harboring a sialyl sugar chain in high yield without decomposing sialic acid at a non-reducing terminal of sugar chain when the glycopeptide is synthesized by a Boc solid phase synthesis method. [Solution to Problem] The present invention is characterized in that the Boc-sialylglycosylated amino acid derivative used in Boc solid phase synthesis method is one where the carboxyl group of the sialic acid at the sugar chain non-reducing terminal is protected with a phenacyl group.Type: GrantFiled: March 5, 2012Date of Patent: July 7, 2015Assignee: Glytech, Inc.Inventors: Yasuhiro Kajihara, Masumi Murakami, Kazuyuki Ishii
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Patent number: 9060958Abstract: The present invention provides a highly safe tyrosinase inhibitor having excellent tyrosinase-inhibiting action, and a method for producing the tyrosinase inhibitor. The method for producing a tyrosinase inhibitor comprises the steps of contacting a live earthworm with hydroxycarboxylic acid powder, diluting the resulting mixture with water to adjust the pH to 2 to 5, and then leaving the resulting dilution to stand for 3 to 180 minutes, or contacting a live earthworm with an aqueous solution of hydroxycarboxylic acid having a pH of 2 to 5 and then leaving the resulting mixture to stand for 3 to 180 minutes; followed by washing the live earthworm with water, grinding the washed earthworm, and then freeze-drying the obtained ground product.Type: GrantFiled: July 24, 2012Date of Patent: June 23, 2015Assignee: WELL STONE CO.Inventors: Yoichi Ishii, Kazuyuki Ishii
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Publication number: 20140377807Abstract: A method for efficiently manufacturing a polypeptide fragment suitable for the NCL method includes a step of reacting a polypeptide containing a first polypeptide fragment having cysteine at the N-terminal and a second polypeptide fragment linked via an intervening sequence -Cys-W-(His)n-Z-Met- with CNBr to obtain a first polypeptide fragment having cysteine at the N-terminal and a third polypeptide fragment, and a step of sequentially reacting the third polypeptide fragment with a compound represented by the following formula (I) and a compound represented by the following formula (II) to obtain a second polypeptide fragment having the C-terminal modified.Type: ApplicationFiled: September 21, 2012Publication date: December 25, 2014Applicant: Glytech, Inc.Inventors: Yasuhiro Kajihara, Ryo Okamoto, Motoharu Kimura, Kazuyuki Ishii
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Publication number: 20140336116Abstract: [Problem] To provide a glycosylated polypeptide having an affinity to somatostatin receptors, and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least one amino acid in a somatostatin or an analog thereof being replaced with a glycosylated amino acid.Type: ApplicationFiled: September 3, 2012Publication date: November 13, 2014Applicant: Glytech, Inc.Inventors: Hirofumi Ochiai, Taiji Shimoda, Kazuhiro Fukae, Masatoshi Maeda, Kazuyuki Ishii, Kenta Yoshida, Katsunari Tezuka, Keisuke Tazuru
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Publication number: 20140249294Abstract: A process for chemically converting a peptide chain into a peptide thioester includes, when a —C(?X)—R1 group is introduced to the thiol group of the cysteine residue and then the resulting peptide is reacted with a compound having a leaving group represented by the formula: —NH—C(?Y)NHR3 in an organic solvent, the —NH—C(?Y)NHR3 group binds via addition reaction to the carboxyl group of the N-terminal-side peptide bond of the cysteine residue, whereby the peptide bond is cleaved and the C-terminal-side peptide fragment is cut off. Further, when the resulting peptide chain having the —NH—C(?Y)NHR3 group is reacted with a thiol in a buffer solution, a thiol exchange reaction occurs, namely, the thiol group of the thiol binds to the carbonyl carbon to which the —NH—C(?Y)NHR3 group has bound, whereby the —NH—C(?Y)NHR3 group is eliminated.Type: ApplicationFiled: January 23, 2014Publication date: September 4, 2014Applicant: GLYTECH, INC.Inventors: Yasuhiro Kajihara, Ryo Okamoto, Izumi Sakamoto, Kazuyuki Ishii
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Publication number: 20140194665Abstract: The present invention relates to a radioactive cesium adsorbent, a method for producing the same, and a method for decontaminating the environment from radioactive cesium with the adsorbent. The radioactive cesium adsorbent of the present invention includes a hydrophilic fiber substrate supporting a Prussian blue analogue, in particular, Prussian blue, and the Prussian blue analogue is immobilized in the inside of the fibers.Type: ApplicationFiled: August 16, 2012Publication date: July 10, 2014Applicant: The Foundation for the Promotion of Industrial ScienceInventors: Kazuyuki Ishii, Masashi Obi, Kazuaki Kudo, Kengo Akagawa, Tetsu Tatsuma, Akiyoshi Sakoda
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Patent number: 8765669Abstract: Oligosaccharide chain added GLP-1 peptides are more stable in blood and more active in controlling blood-sugar levels than GLP-1 peptides without added oligosaccharides. Oligosaccharide chain added GLP-1 peptides having GLP-1 activity include at least one or at least two amino acids each substituted with an oligosaccharide chain added amino acid in GLP-1; a peptide having the amino acid sequence of GLP-1 with deletion, substitution or addition of one or several amino acids; or a GLP-1 analog. Oligosaccharide chain added GLP-1 peptides with at least one amino acid substituted with an oligosaccharide chain added amino acid include an oligosaccharide chain with oligo hyaluronic acid. Oligosaccharide chain added amino acids include oligosaccharide chains attached to amino acids via linkers.Type: GrantFiled: June 15, 2009Date of Patent: July 1, 2014Assignee: Glytech, Inc.Inventors: Yasuhiro Kajihara, Takashi Tsuji, Izumi Sakamoto, Yuri Nambu, Naohiro Hayashi, Kazuyuki Ishii, Kazuhiro Fukae, Katsunari Tezuka, Hiroaki Asai
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Publication number: 20140154331Abstract: The present invention provides a highly safe tyrosinase inhibitor having excellent tyrosinase-inhibiting action, and a method for producing the tyrosinase inhibitor. The method for producing a tyrosinase inhibitor comprises the steps of contacting a live earthworm with hydroxycarboxylic acid powder, diluting the resulting mixture with water to adjust the pH to 2 to 5, and then leaving the resulting dilution to stand for 3 to 180 minutes, or contacting a live earthworm with an aqueous solution of hydroxycarboxylic acid having a pH of 2 to 5 and then leaving the resulting mixture to stand for 3 to 180 minutes; followed by washing the live earthworm with water, grinding the washed earthworm, and then freeze-drying the obtained ground product.Type: ApplicationFiled: July 24, 2012Publication date: June 5, 2014Applicant: Well Stone Co.Inventors: Yoichi Ishii, Kazuyuki Ishii