Patents by Inventor Kazuyuki Tabata
Kazuyuki Tabata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11964527Abstract: A vehicle stabilizer system, including: a stabilizer device and a switching mechanism to switch a roll suppressing function by a stabilizer bar between an effective state in which the roll suppressing function is rendered effective and an ineffective state in which the roll suppressing function is rendered ineffective; and a controller configured to determine whether a lateral acceleration of a vehicle body is greater than a threshold lateral acceleration and control the switching mechanism to render the roll suppressing function effective when the lateral acceleration is greater than the threshold lateral acceleration and ineffective when the lateral acceleration is not greater than the threshold lateral acceleration, wherein the controller employs, as a determination lateral acceleration for determining whether the lateral acceleration is greater than the threshold lateral acceleration, a smaller one of an actual lateral acceleration and an estimated lateral acceleration estimated based on a turning degreeType: GrantFiled: July 21, 2021Date of Patent: April 23, 2024Assignee: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Masaaki Tabata, Kazuyuki Murata, Masashi Yamamoto
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Patent number: 11136375Abstract: The present invention provides a method of producing a recombinant antibody efficiently and at low cost. Disclosed is a method of producing an antibody or a fragment thereof, comprising allowing a cell to produce the antibody or the fragment, wherein the cell contains a larger number of copies of an exogenous DNA encoding the light chain or a fragment thereof of the antibody than the number of copies contained in the cell of an exogenous DNA encoding the heavy chain or a fragment thereof of the antibody. The present invention also provides a recombinant vector comprising one copy of a DNA encoding the heavy chain or a fragment thereof of an antibody and two or more copies of a DNA encoding the light chain or a fragment thereof of the antibody; and a transformant.Type: GrantFiled: May 8, 2017Date of Patent: October 5, 2021Assignee: Chugai Seiyaku Kabushiki KaishaInventors: Yoshiki Yamada, Tatsuya Kiyasu, Kazuyuki Tabata, Akihiro Kuzumaki, Mai Yamashiro
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Publication number: 20210300996Abstract: The present invention provides a method of producing a recombinant antibody efficiently and at low cost. Disclosed is a method of producing an antibody or a fragment thereof, comprising allowing a cell to produce the antibody or the fragment, wherein the cell contains a larger number of copies of an exogenous DNA encoding the light chain or a fragment thereof of the antibody than the number of copies contained in the cell of an exogenous DNA encoding the heavy chain or a fragment thereof of the antibody. The present invention also provides a recombinant vector comprising one copy of a DNA encoding the heavy chain or a fragment thereof of an antibody and two or more copies of a DNA encoding the light chain or a fragment thereof of the antibody; and a transformant.Type: ApplicationFiled: April 16, 2021Publication date: September 30, 2021Applicant: Chugai Seiyaku Kabushiki KaishaInventors: Yoshiki YAMADA, Tatsuya KIYASU, Kazuyuki TABATA, Akihiro KUZUMAKI, Mai YAMASHIRO
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Publication number: 20170275351Abstract: The present invention provides a method of producing a recombinant antibody efficiently and at low cost. Disclosed is a method of producing an antibody or a fragment thereof, comprising allowing a cell to produce the antibody or the fragment, wherein the cell contains a larger number of copies of an exogenous DNA encoding the light chain or a fragment thereof of the antibody than the number of copies contained in the cell of an exogenous DNA encoding the heavy chain or a fragment thereof of the antibody. The present invention also provides a recombinant vector comprising one copy of a DNA encoding the heavy chain or a fragment thereof of an antibody and two or more copies of a DNA encoding the light chain or a fragment thereof of the antibody; and a transformant.Type: ApplicationFiled: May 8, 2017Publication date: September 28, 2017Applicant: Chugai Seiyaku Kabushiki KaishaInventors: Yoshiki Yamada, Tatsuya Kiyasu, Kazuyuki Tabata, Akihiro Kuzumaki, Mai Yamashiro
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Patent number: 9683027Abstract: The present invention provides a method of producing a recombinant antibody efficiently and at low cost. Disclosed is a method of producing an antibody or a fragment thereof, comprising allowing a cell to produce the antibody or the fragment, wherein the cell contains a larger number of copies of an exogenous DNA encoding the light chain or a fragment thereof of the antibody than the number of copies contained in the cell of an exogenous DNA encoding the heavy chain or a fragment thereof of the antibody. The present invention also provides a recombinant vector comprising one copy of a DNA encoding the heavy chain or a fragment thereof of an antibody and two or more copies of a DNA encoding the light chain or a fragment thereof of the antibody; and a transformant.Type: GrantFiled: October 14, 2008Date of Patent: June 20, 2017Assignee: Chugai Seiyaku Kabushiki KaishaInventors: Yoshiki Yamada, Tatsuya Kiyasu, Kazuyuki Tabata, Akihiro Kuzumaki, Mai Yamashiro
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Publication number: 20100291627Abstract: The present invention provides a method of producing a recombinant antibody efficiently and at low cost. Disclosed is a method of producing an antibody or a fragment thereof, comprising allowing a cell to produce the antibody or the fragment, wherein the cell contains a larger number of copies of an exogenous DNA encoding the light chain or a fragment thereof of the antibody than the number of copies contained in the cell of an exogenous DNA encoding the heavy chain or a fragment thereof of the antibody. The present invention also provides a recombinant vector comprising one copy of a DNA encoding the heavy chain or a fragment thereof of an antibody and two or more copies of a DNA encoding the light chain or a fragment thereof of the antibody; and a transformant.Type: ApplicationFiled: October 14, 2008Publication date: November 18, 2010Inventors: Yoshiki Yamada, Tatsuya Kiyasu, Kazuyuki Tabata, Akihiro Kuzumaki, Mai Yamashiro
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Publication number: 20060121587Abstract: Disclosed is a process for producing actinol from ketoisophorone which comprises contacting ketoisophorone with a recombinant microorganism or cell-free extract thereof in a reaction mixture, wherein said recombinant microorganism is obtainable by transforming a host microorganism, e.g. selected from the group consisting of microorganisms of the genera Saccharomyces, Zygosaccharomyces, and Candida, such as commercially available baker's yeast, Saccharomyces cerevisiae ATCC7754, Saccharomyces rouxii (Zygosaccharomyces rouxii) HUT7191 (IFO 0494), Saccharomyces delbrueckii HUIT7116 (Saccharomyces unisporus IFO 0298), Saccharomyces delbrueckii (Torulaspora delbrueckii) HUT7102, Saccharomyces willianus HU7106, Zygosaccharomyces bailii ATCC11486, Candida tropicalis IFO 1403, and a mutant thereof, which is capable of reducing ketoisophorone to levodione with a levodione reductase gene, e.g. a levodione reductase gene derived from a microorganism belonging to the genus Corynebacterium, such as C.Type: ApplicationFiled: September 16, 2003Publication date: June 8, 2006Inventors: Tatsuo Hoshino, Yutaka Setoguchi, Sakayu Shimizu, Kazuyuki Tabata
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Publication number: 20060121586Abstract: The present invention relates to processes for producing (4S)-4-hydroxy-2,6,6-trimethyl-2-cyclohexene-1-one (phorenol) from 2,6,6-trimethyl-2-cyclohexene-1,4-dione (ketoisophorone). The present invention also relates to products useful for producing phorenol from ketoisophorone, including microorganisms, cell-free extracts of such microorganisms, recombinant microorganisms, cell-free extracts of such recombinant microorganisms, and enzymes (e.g., levodione reductase). Processes for producing phorenol from ketoisophorone using such products are also provided.Type: ApplicationFiled: May 9, 2003Publication date: June 8, 2006Inventors: Tatsuo Hoshino, Yutaka Setoguchi, Sakayu Shimizu, Kazuyuki Tabata