Abstract: Bi-specific chimeric antigen receptors (CARs) capable of binding to both CD19 and CD22 and immune cells expressing such. Also provided herein are therapeutic uses of such immune cells (e.g., CAR-T cells) for eliminating disease cells such as cancer cells.

Abstract: A winding system may include a plurality of metal plates including the same shape and size, such that the plates are stacked, and each of the plurality of metal plates is reversely positioned with respect to a gap pattern in an adjacent one of the plurality of metal plates. The plates are simultaneously brazed together while flow of molten brazing material is constrained by grooves formed on brazing tabs of the plates.

Abstract: An example disclosed method includes defining a first zone within a monitored area, a first group of receivers covering the first zone; defining a second zone within the monitored area, a second group of receivers covering the second zone; determining, via a processor, a first position of a first tag based on timing measurements obtained via the first group of receivers; determining, via the processor, whether the first position indicates that the first tag is within the first zone; and when the first position indicates that the first tag is not within the first zone, not reporting data associated with the first tag.

Abstract: A winding system may include a plurality of metal plates including the same shape and size, such that the plates are stacked, and each of the plurality of metal plates is reversely positioned with respect to a gap pattern in an adjacent one of the plurality of metal plates. The plates are simultaneously brazed together while flow of molten brazing material is constrained by grooves formed on brazing tabs of the plates.

Abstract: A winding system may include a plurality of metal plates including the same shape and size, such that the plates are stacked, and each of the plurality of metal plates is reversely positioned with respect to a gap pattern in an adjacent one of the plurality of metal plates. The plates are simultaneously brazed together while flow of molten brazing material is constrained by grooves formed on brazing tabs of the plates.

Abstract: The present invention relates to a ceramic toilet pan with handrails, comprising a ceramic toilet pan body and a water tank. Handrails are respectively arranged on both sides of the ceramic toilet pan body and the water tank, and the handrails, the ceramic toilet pan body and the water tank are formed integrally to form an integral structure. The present invention has the advantages of simple structure, novel and beautiful appearance, low cost, convenient cleaning, no need of other supporting facilities, no need of additional installation and small occupation area, the ceramic toilet pan with handrails is suitable for installation and use in bathrooms of families, public places and the like, and satisfies the need of going to the toilet for people having difficulty in moving, such as the old, the weak, the sick, the disabled and the pregnant.

Abstract: An example disclosed method includes defining a first zone within a monitored area, a first group of receivers covering the first zone; defining a second zone within the monitored area, a second group of receivers covering the second zone; determining, via a processor, a first position of a first tag based on timing measurements obtained via the first group of receivers; determining, via the processor, whether the first position indicates that the first tag is within the first zone; and when the first position indicates that the first tag is not within the first zone, not reporting data associated with the first tag.

Abstract: A winding system may include a plurality of metal plates including the same shape and size, such that the plates are stacked, and each of the plurality of metal plates is reversely positioned with respect to a gap pattern in an adjacent one of the plurality of metal plates. The plates are simultaneously brazed together while flow of molten brazing material is constrained by grooves formed on brazing tabs of the plates.

Abstract: An ultra wideband (UWB) or short-pulse RF system is disclosed that can be used to precisely locate or track objects (such as personnel, equipment, assets, etc.) in real-time in an arbitrarily large, physically connected or disconnected, multipath and/or noisy environment. A system implementation includes multiple zones or groups of receivers that receives RF signals transmitted by one or more timing reference tags and one or more objects having associated object tags. Each zone or group may share a common receiver. By combining a multiple reference tag system with a virtual group of receivers, i.e., a zoning technique or system, a cost-effective system can be provided that offers scalability and flexibility to monitor a significantly expanded coverage area.

Abstract: A boosting AC-to-DC converter An AC-to-DC converter may include a main rectifier, a first auxiliary rectifier, a second auxiliary rectifiers and a transformer assembly. The transformer assembly may include a set of primary windings arranged in a first multiphase configuration and connected to the main rectifier, a first set of secondary windings arranged in a second multiphase relationship and connected to the first auxiliary rectifier and a second set of secondary windings arranged in a third multiphase configuration and connected to the second auxiliary rectifier. The second multiphase configuration of the first set of secondary windings and the third multiphase configuration of the second set of secondary windings may be in phase shifting relationships relative to the first multiphase configuration of the set of primary windings.

Abstract: An implantable blood pump includes motor control circuitry and power electronics circuitry integrated within the implantable pump body. The motor control circuitry and power electronics circuitry is configured to energize and control motor windings to rotate the pump rotor and impeller. Additional control circuitry and power electronics circuitry may be integrated within the pump housing to energize and control magnetic bearings of a magnetic levitation pump. A percutaneous cable coupled between the implantable blood pump and an extracorporeal monitor includes a reduced number of leads to provide power and control signals to the implantable blood pump. Wireless communication between the extracorporeal monitor and the integrated power electronics and control circuitry facilitates the use of a percutaneous cable with as few as two leads for providing power to the implantable pump.

Abstract: An implantable blood pump includes motor control circuitry and power electronics circuitry integrated within the implantable pump body. The motor control circuitry and power electronics circuitry is configured to energize and control motor windings to rotate the pump rotor and impeller. Additional control circuitry and power electronics circuitry may be integrated within the pump housing to energize and control magnetic bearings of a magnetic levitation pump. A percutaneous cable coupled between the implantable blood pump and an extracorporeal monitor includes a reduced number of leads to provide power and control signals to the implantable blood pump. Wireless communication between the extracorporeal monitor and the integrated power electronics and control circuitry facilitates the use of a percutaneous cable with as few as two leads for providing power to the implantable pump.

Abstract: The present invention discloses dry-steamed fine dried noodles. The dry-steamed fine dried noodles with a moisture content of less than or equal to 14.5% are prepared via the processes of dry-steaming, cooling and tempering by using fine dried noodles with a moisture content of 10%-16% as raw material. Compared with the control noodles, the maximum load of the dry-steamed fine dried noodles is improved by 10%-200%, and the cooking loss rate is reduced by 0.5%-1.5%. The dry-steamed fine dried noodles have good taste, boiling fastness, long shelf life, and good edible quality and cooking performance.

Abstract: A winding system may include a plurality of metal plates including the same shape and size, such that the plates are stacked, and each of the plurality of metal plates is reversely positioned with respect to a gap pattern in an adjacent one of the plurality of metal plates.

Abstract: A nearly 2 to 1 boosting mufti-phase AC-to-DC converter may include a main rectifier, an auxiliary rectifier; and an autotransformer connected to the main rectifier and the auxiliary rectifier. The autotransformer may include a plurality of interconnected windings arranged in a plurality of legs, with one of the legs for each phase and with each leg including a plurality of windings, wherein all but one of the windings of each leg have equal turns ratios and one of the windings of each leg has a turns ratio that is less than the turns ratio of all of the other windings of the respective leg.

Abstract: A boosting AC-to-DC converter may include a main rectifier, first and second auxiliary rectifiers, and an autotransformer. The autotransformer may include a plurality of winding assemblies each having a primary terminal connected to an AC power source, a main secondary terminal connected to the main rectifier, a first auxiliary secondary terminal connected to the first auxiliary rectifier, and a second auxiliary secondary terminal connected to the second auxiliary rectifier. Impedance between the primary terminal of each of the winding assemblies and the main rectifier is less than impedance between the primary terminal of each of the winding assemblies and either the first auxiliary rectifier or the second auxiliary rectifier. Impedance between the primary terminal of each of the first winding assemblies and the first auxiliary rectifier is different from impedance between the primary terminal of each of the winding assemblies and the second auxiliary rectifier.

Abstract: A boosting AC-to-DC converter may include a main rectifier, first and second auxiliary rectifiers, and an autotransformer. The autotransformer may include a plurality of winding assemblies each having a primary terminal connected to an AC power source, a main secondary terminal connected to the main rectifier, a first auxiliary secondary terminal connected to the first auxiliary rectifier, and a second auxiliary secondary terminal connected to the second auxiliary rectifier. Impedance between the primary terminal of each of the winding assemblies and the main rectifier is less than impedance between the primary terminal of each of the winding assemblies and either the first auxiliary rectifier or the second auxiliary rectifier. Impedance between the primary terminal of each of the first winding assemblies and the first auxiliary rectifier is different from impedance between the primary terminal of each of the winding assemblies and the second auxiliary rectifier.

Abstract: A boosting AC-to-DC converter An AC-to-DC converter may include a main rectifier, a first auxiliary rectifier, a second auxiliary rectifiers and a transformer assembly. The transformer assembly may include a set of primary windings arranged in a first multiphase configuration and connected to the main rectifier, a first set of secondary windings arranged in a second multiphase relationship and connected to the first auxiliary rectifier and a second set of secondary windings arranged in a third multiphase configuration and connected to the second auxiliary rectifier. The second multiphase configuration of the first set of secondary windings and the third multiphase configuration of the second set of secondary windings may be in phase shifting relationships relative to the first multiphase configuration of the set of primary windings.

Abstract: Various methods and apparatuses that utilize a wireless time reference system are provided herein. One example method involves calibrating independent, spatially-located clocks of a geoposition system in order to geolocate an object having an associated object tag. The example method may include transmitting an RF pulse pair, receiving the pulse pair at multiple locations, utilizing respective frequencies of first and second spatially-located clocks to produce count values to effect measurement of an interarrival interval at each of multiple locations, determining a ratio of count values relative to said first and second spatially-located clocks, and utilizing said ratio to calibrate time indications of said clocks. Other related methods and apparatus are also provided.

Abstract: A nearly 2 to 1 boosting mufti-phase AC-to-DC converter may include a main rectifier, an auxiliary rectifier; and an autotransformer connected to the main rectifier and the auxiliary rectifier. The autotransformer may include a plurality of interconnected windings arranged in a plurality of legs, with one of the legs for each phase and with each leg including a plurality of windings, wherein all but one of the windings of each leg have equal turns ratios and one of the windings of each leg has a turns ratio that is less than the turns ratio of all of the other windings of the respective leg.