Abstract: A tissue factor (TF)-targeted antibody-drug conjugate (ADC) and a method for preparing the ADC. The ADC is capable of binding to TF antigen with high specificity, and has high affinity, low immunogenicity, high cytotoxicity, and significant anti-tumor activity.

Abstract: Methods and systems for streaming content are disclosed. A manifest request is received from a streaming video player. A stitcher service generates the requested manifest, comprising primary content locators for corresponding segments of primary content, a placeholder for a secondary content pod, and an indication as to when the secondary content pod is to be played. The manifest is transmitted to the video player. A session identifier indicating a time to a next secondary content pod is placed on an asynchronous bus and is accessed by a session service. The session service generates a secondary content pod request which is accessed by a secondary content pod service. One or more secondary content pod decisions are generated. A request for a secondary content pod file is received from the video player. The secondary content pod file, comprising locators for items of secondary content is generated and provided to the video player.

Abstract: A button structure includes a switch, a shell, an elastic member, a button and at least one adjustable limiting member. The elastic member includes a fixing portion, a compressive portion and an elastic portion. The fixing portion is connected to the shell. The compressive portion is configured to abut against the switch. The elastic portion is connected between the fixing portion and the compressive portion. The elastic portion is suitable for deformation. The button is connected to the compressive portion, and the compressive portion is located between the button and the switch. The adjustable limiting member is disposed on the button, and is configured to abut against the elastic portion. The adjustable limiting member adjustably protrudes for a length toward the elastic portion relative to the button.

Abstract: A vehicle rear seat display with a multifunctional eye protection light is provided, and the vehicle rear seat display with a multifunctional eye protection light includes a display, a multifunctional eye protection light, and a connecting piece. The multifunctional eye protection light is retractably disposed on the back of the display through the connecting piece, and the multifunctional eye protection light is also rotated vertically along the connecting piece to adjust the light-illuminating angle according to the user's usage situation.

Abstract: A dual-shaft dual-screen roof-mounted vehicle display is provided. The dual-shaft dual-screen roof-mounted display has a roof mount, a first display, a second display, a first rotating shaft, and a second rotating shaft. The first display is connected to the roof mount and the second display via the first rotating shaft and the second rotating shaft respectively, and the first display and the second display may be retracted through the first rotating shaft and the second rotating shaft, improving the functionality of the roof-mounted display.

Abstract: Disclosed by the present invention are a targeted CD73 antibody and an antibody-drug conjugate (ADC), and a preparation method therefor and application thereof. Further disclosed is a method for preparing the described monoclonal antibody and ADC. The monoclonal antibody and the corresponding ADC disclosed by the present invention can be efficiently and highly specifically combined with purified CD73 protein and CD73 on the surfaces of multiple tumor cells to block the catalytic activity of CD73 enzyme, and have high affinity, low immunogenicity and significant anti-tumor effect.

Abstract: A mobility assistance device and a driving method thereof are provided. The mobility assistance device includes at least one bracket and a driving device which drives the at least one bracket. The driving device includes a brushless direct current (DC) motor, a rotor angle sensor, and a sensing driver. The rotor angle sensor senses the angle of the brushless DC motor. The sensing driver uses a corresponding algorithm to estimate a corresponding angle corresponding to an angle velocity switching of the brushless DC motor. The corresponding angle is used as an angle of the brushless DC motor. The sensing driver drives the brushless DC motor according to the corresponding angle, so that the brushless DC motor provides supporting force to the at least one bracket.

Abstract: Disclosed are a new AXL-targeting monoclonal antibody and antibody-drug conjugate. Also disclosed is a method for preparing said antibody and antibody-drug conjugate. The AXL antibody of the present invention can bind with purified human AXL protein and multiple AXL on tumor cell surface with high effectiveness and high specificity. Said humanized antibody also has high affinity and low immunogenicity. Said AXL antibody-drug conjugate has markable performance against tumors having high AXL expression.

Abstract: A tissue factor (TF)-targeted antibody-drug conjugate (ADC) and a method for preparing the ADC. The ADC is capable of binding to TF antigen with high specificity, and has high affinity, low immunogenicity, high cytotoxicity, and significant anti-tumor activity.

Abstract: A force applying auxiliary device and a control method thereof are provided. The force applying auxiliary device includes a sensor group, a processor, and a force applying driver. The sensor group includes a first sensor disposed on a first side and a second sensor disposed on a second side. The processor collects motion posture data of a user according to the first sensor and the second sensor, and determines whether a motion of the user is abnormal. When determining that the motion of the user is abnormal, the processor selects at least one preset abnormal pattern as a specific abnormal pattern according to the motion posture data, and controls the force applying driver to provide a force by using the specific abnormal pattern. A force difference between first and second forces applied to first and second side feet is adjusted based on a difference in sampling values between the sensors.

Abstract: In one embodiment, an apparatus comprises processing circuitry to: receive wireless signal data corresponding to an RFID tag, wherein the wireless signal data comprises signal strength data and signal phase data corresponding to wireless signals transmitted by the RFID tag and received by an RFID reader; generate decomposed signal strength data based on a seasonal decomposition of the signal strength data; generate a frequency-phase curve based on the signal phase data; extract a set of signal strength features based on the decomposed signal strength data; extract a set of signal phase features based on the frequency-phase curve; and detect a motion state of the RFID tag using a machine learning classifier, wherein the machine learning classifier is trained to detect the motion state based on the set of signal strength features and the set of signal phase features.

Abstract: A speaker device includes a housing body, a speaker driver and a passive radiator. The housing body is formed with a first sound hole and a second sound hole respectively opening in two opposite directions. The speaker driver is disposed in the housing body, is located adjacent to the first sound hole, and is adapted to generate sound. The passive radiator is disposed in the housing body, is located adjacent to the second sound hole, and is adapted to generate sound. The first sound hole and the second sound hole are adapted for respectively allowing the sound generated by the speaker driver and the sound generated by the passive radiator to travel out from the housing body respectively in two opposite directions therethrough.

Abstract: The present disclosure relates to image processing. The method includes acquiring at least one of a backward propagation feature of an (x+1)th video frame in a video segment or a forward propagation feature of an (x?1)th video frame in the video segment. The video segment includes N video frames, N being an integer greater than 2, and x being an integer. The method further includes deriving a reconstruction feature of the xth video frame from at least one of the xth video frame, the backward propagation feature of the (x+1)th video frame, or the forward propagation feature of the (x?1)th video frame, and deriving a target video frame corresponding to the xth video frame by reconstructing the xth video frame based on the reconstruction feature of the xth video frame. The target video frame has resolution higher than that of the xth video frame.

Abstract: A tissue factor (TF)-targeted antibody-drug conjugate (ADC) and a method for preparing the ADC. The ADC is capable of binding to TF antigen with high specificity, and has high affinity, low immunogenicity, high cytotoxicity, and significant anti-tumor activity.

Abstract: Enclosed are embodiments for diagnosis and monitoring of bruxism using earbud motion sensors. In an embodiment, a method comprises: receiving, with at least one processor, a signal derived from a motion sensor in an earbud, wherein the signal is captured while the earbud is inserted in an ear of a user; segmenting, with the at least one processor, the signal into segments; extracting, with the at least one processor, features from the segments; classifying, with the at least one processor, the features; and determining, with the at least one processor, that orofacial activity is predicted based on the classifying.

Abstract: A mobility assistance device and a driving method thereof are provided. The mobility assistance device includes at least one bracket and a driving device which drives the at least one bracket. The driving device includes a brushless direct current (DC) motor, a rotor angle sensor, and a sensing driver. The rotor angle sensor senses the angle of the brushless DC motor. The sensing driver uses a corresponding algorithm to estimate a corresponding angle corresponding to an angle velocity switching of the brushless DC motor. The corresponding angle is used as an angle of the brushless DC motor. The sensing driver drives the brushless DC motor according to the corresponding angle, so that the brushless DC motor provides supporting force to the at least one bracket.

Abstract: A speaker device includes a housing body, a speaker driver and a passive radiator. The housing body is formed with a first sound hole and a second sound hole respectively opening in two opposite directions. The speaker driver is disposed in the housing body, is located adjacent to the first sound hole, and is adapted to generate sound. The passive radiator is disposed in the housing body, is located adjacent to the second sound hole, and is adapted to generate sound. The first sound hole and the second sound hole are adapted for respectively allowing the sound generated by the speaker driver and the sound generated by the passive radiator to travel out from the housing body respectively in two opposite directions therethrough.

Abstract: In one embodiment, an apparatus comprises processing circuitry to: receive wireless signal data corresponding to an RFID tag, wherein the wireless signal data comprises signal strength data and signal phase data corresponding to wireless signals transmitted by the RFID tag and received by an RFID reader; generate decomposed signal strength data based on a seasonal decomposition of the signal strength data; generate a frequency-phase curve based on the signal phase data; extract a set of signal strength features based on the decomposed signal strength data; extract a set of signal phase features based on the frequency-phase curve; and detect a motion state of the RFID tag using a machine learning classifier, wherein the machine learning classifier is trained to detect the motion state based on the set of signal strength features and the set of signal phase features.

Abstract: A force applying auxiliary device and a control method thereof are provided. The force applying auxiliary device includes a sensor group, a processor, and a force applying driver. The sensor group includes a first sensor disposed on a first side and a second sensor disposed on a second side. The processor collects motion posture data of a user according to the first sensor and the second sensor, and determines whether a motion of the user is abnormal. When determining that the motion of the user is abnormal, the processor selects at least one preset abnormal pattern as a specific abnormal pattern according to the motion posture data, and controls the force applying driver to provide a force by using the specific abnormal pattern. A force difference between first and second forces applied to first and second side feet is adjusted based on a difference in sampling values between the sensors.

Abstract: A method for image restoration, an electronic device and a computer storage medium are provided. The method includes that: region division is performed on an acquired image to obtain more than one sub-image; each sub-image is input into multiple paths of neural network and restored by using a restoration network determined for each sub-image; a restored image of each sub-image is output and obtained, so as to obtain a restored image of the acquired image.