Patents by Inventor Keats Nelms

Keats Nelms has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heparanase inhibitors and use thereof
    Patent number: 11787783
    Abstract: The invention relates to functionalized dihydro- and tetrahydro-quinazoline compounds, pharmaceutical compositions comprising such compounds, and the use of such compounds as heparanase inhibitors for the treatment of diseases or conditions related to heparanase.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: October 17, 2023
    Assignee: Beta Therapeutics Pty Ltd
    Inventors: Keats Nelms, Brett Schwartz, Colin Jackson, Martin Banwell, Edward Hammond
  • Heparanase inhibitors and use thereof
    Patent number: 11718609
    Abstract: The invention relates to functionalized quinazoline compounds, pharmaceutical compositions comprising such compounds, and the use of such compounds as heparanase inhibitors for the treatment of diseases or conditions related to heparanse activity.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: August 8, 2023
    Assignee: BETA THERAPEUTICS PTY LTD
    Inventors: Keats Nelms, Brett Schwartz, Colin Jackson, Martin Banwell, Edward Hammond
  • Heparanase Inhibitors and Use Thereof
    Publication number: 20210130338
    Abstract: The invention relates to functionalized quinazoline compounds, pharmaceutical compositions comprising such compounds, and the use of such compounds as heparanase inhibitors for the treatment of diseases or conditions related to heparanse activity.
    Type: Application
    Filed: December 13, 2017
    Publication date: May 6, 2021
    Inventors: Keats NELMS, Brett SCHWARTZ, Colin JACKSON, Martin BANWELL, Edward HAMMOND
  • Methods of Treating Ocular Disorders
    Publication number: 20200093852
    Abstract: This invention relates to the use of a heparanase inhibitor for treating, or inhibiting the progression or development of, an ocular inflammatory disorder, such as age-related macular degeneration, diabetic retinopathy, retinitis pigmentosa, retinal 5 vein occlusion, retinoblastoma, uveitis, macular edema, dry eye, ocular inflammation associated with an infection or keratoconus.
    Type: Application
    Filed: December 13, 2017
    Publication date: March 26, 2020
    Inventors: Keats NELMS, Riccardo NATOLI, Brett SCHWARTZ
  • HEPARANASE INHIBITORS AND USE THEREOF
    Publication number: 20190345143
    Abstract: The invention relates to functionalized dihydro- and tetrahydro-quinazoline compounds, pharmaceutical compositions comprising such compounds, and the use of such compounds as heparanase inhibitors for the treatment of diseases or conditions related to heparanase.
    Type: Application
    Filed: December 13, 2017
    Publication date: November 14, 2019
    Inventors: Keats NELMS, Brett SCHWARTZ, Colin JACKSON, Martin BANWELL, Edward HAMMOND
  • Sensin polypeptides, encoding nucleic acids, mutations, and methods of their identification and use
    Publication number: 20050015821
    Abstract: The present invention relates to the discovery, identification, and characterization of novel genes encoding proteins that share sequence similarity with animal zinc finger proteins. The invention encompasses the described polynucleotides, the encoded proteins, fusion proteins, polypeptides and peptides, genetically engineered animals that either under- or over-express the disclosed sequences, antibodies to the encoded proteins and peptides, host cell expression systems, antagonists and agonists of the proteins, and other compounds that modulate the expression or activity of the proteins encoded by the disclosed sequences that can be used for diagnosis, drug screening, clinical trial monitoring and the treatment of diseases and disorders.
    Type: Application
    Filed: February 20, 2004
    Publication date: January 20, 2005
    Inventors: Richard Glynne, Nancy Hong, Keats Nelms, Hua Wu