Patents by Inventor Kedarnath Sastry

Kedarnath Sastry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210301296
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Application
    Filed: June 4, 2021
    Publication date: September 30, 2021
    Inventors: NAGARAJ GOVINDAPPA, KEDARNATH SASTRY, MARIA MELINA SOARES
  • Patent number: 11028399
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: June 8, 2021
    Inventors: Nagaraj Govindappa, Kedarnath Sastry, Maria Melina Soares
  • Publication number: 20190367929
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Application
    Filed: June 18, 2019
    Publication date: December 5, 2019
    Inventors: NAGARAJ GOVINDAPPA, KEDARNATH SASTRY, MARIA MELINA SOARES
  • Patent number: 10385348
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: August 20, 2019
    Assignee: BIOCON LIMITED
    Inventors: Nagaraj Govindappa, Kedarnath Sastry, Maria Melina Soares
  • Patent number: 10144934
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: December 4, 2018
    Assignee: BIOCON LIMITED
    Inventors: Nagaraj Govindappa, Kedarnath Sastry, Maria Melina Soares
  • Publication number: 20180066057
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Application
    Filed: October 27, 2017
    Publication date: March 8, 2018
    Inventors: Nagaraj Govindappa, Kedarnath Sastry, Maria Melina Soares
  • Patent number: 9809651
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: November 7, 2017
    Assignee: BIOCON LIMITED
    Inventors: Nagaraj Govindappa, Kedarnath Sastry, Maria Melina Soares
  • Patent number: 9758582
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: September 12, 2017
    Assignee: BIOCON LIMITED
    Inventors: Nagaraj Govindappa, Kedarnath Sastry, Maria Melina Soares
  • Publication number: 20170233747
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Application
    Filed: February 28, 2017
    Publication date: August 17, 2017
    Inventors: NAGARAJ GOVINDAPPA, KEDARNATH SASTRY, MARIA MELINA SOARES
  • Publication number: 20160237155
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Application
    Filed: May 3, 2016
    Publication date: August 18, 2016
    Inventors: NAGARAJ GOVINDAPPA, KEDARNATH SASTRY, MARIA MELINA SOARES
  • Publication number: 20160168260
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Application
    Filed: February 18, 2016
    Publication date: June 16, 2016
    Inventors: NAGARAJ GOVINDAPPA, KEDARNATH SASTRY, MARIA MELINA SOARES
  • Patent number: 9340617
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Grant
    Filed: August 13, 2014
    Date of Patent: May 17, 2016
    Assignee: BIOCON LIMITED
    Inventors: Nagaraj Govindappa, Kedarnath Sastry, Maria Melina Soares
  • Patent number: 9070015
    Abstract: A system and a method for iris detection in a face region of a digital image are disclosed. In one embodiment, iris is detected in the face region of the digital image using eye features, such as a shape of the iris and/or luminance values of a sclera region.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: June 30, 2015
    Assignee: ITTIAM SYSTEMS (P) LTD.
    Inventors: Hamsalekha Sridhara, Srinivasan Ekabaram, Omkar Kedarnath Sastry, Murali Babu Muthukrishnan
  • Patent number: 8975041
    Abstract: The present invention relates to novel Prolipase-Bovine trypsinogen (PLBTR) fusion proteins, the genes encoding them, and the production and uses thereof. More specifically, the present invention relates to methods of producing in optimal quantities PLBTR fusion proteins which comprise a heterologous polypeptide which is normally susceptible to autocatalytic activity. More particularly, the present invention relates to fusion proteins which comprise an heterologous polypeptide, such as a serine protease, fused to a lipase signal sequence, which can be expressed by recombinant host cells in desired amounts. The present invention further relates to polynucleotides encoding such fusion proteins, to expression vectors for expression of such fusion proteins, to host cells transformed with such polynucleotides/vectors, and to methods of generating such fusion proteins.
    Type: Grant
    Filed: October 26, 2009
    Date of Patent: March 10, 2015
    Assignee: Biocon Limited
    Inventors: Nagaraj Govindappa, Nandini Nataraj, Sanjay Tiwari, Partha Hazra, Mukesh Babuappa Patale, Gokul Jothiraman, Kedarnath Sastry
  • Publication number: 20140356362
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Application
    Filed: August 13, 2014
    Publication date: December 4, 2014
    Inventors: NAGARAJ GOVINDAPPA, KEDARNATH SASTRY, MARIA MELINA SOARES
  • Patent number: 8815247
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: August 26, 2014
    Assignee: Biocon Limited
    Inventors: Nagaraj Govindappa, Kedarnath Sastry, Maria Melina Soares
  • Publication number: 20140219516
    Abstract: A system and a method for iris detection in a face region of a digital image are disclosed. In one embodiment, iris is detected in the face region of the digital image using eye features, such as a shape of the iris and/or luminance values of a sclera region.
    Type: Application
    Filed: February 7, 2013
    Publication date: August 7, 2014
    Applicant: ITTIAM SYSTEMS (P) LTD.
    Inventors: HAMSALEKHA SRIDHARA, SRINIVASAN EKABARAM, OMKAR KEDARNATH SASTRY, MURALI BABU MUTHUKRISHNAN
  • Patent number: 8693740
    Abstract: A method and architecture for face detection under varying light conditions, tilt levels, different color characteristics of faces in a digital image are disclosed. In one embodiment, skin pixels in the digital image are selected. Any unselected pixels are then classified into bright pixels and dark pixels. Skin pixels are then selected from the bright pixels. Skin pixels are further selected from the dark pixels. All the skin pixels are then grouped into windows. Any window having skin pixels that is more than or equal to a predetermined number of skin pixels is then declared as a skin window. Candidate face regions are then formed by grouping the skin windows. Boundaries of candidate face regions are then determined. Eye regions are then determined in the boundaries of candidate face regions. Each candidate face region is then declared as a face, if the eye regions are determined in it.
    Type: Grant
    Filed: November 7, 2012
    Date of Patent: April 8, 2014
    Assignee: Ittiam Systems (P) Ltd.
    Inventors: Hamsalekha Sridhara, Omkar Kedarnath Sastry, Srinivasan Ekabaram, Murali Babu Muthukrishnan
  • Publication number: 20130287802
    Abstract: The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
    Type: Application
    Filed: March 13, 2013
    Publication date: October 31, 2013
    Applicant: BIOCON LIMITED
    Inventors: NAGARAJ GOVINDAPPA, Kedarnath Sastry, Maria Melina Soares
  • Publication number: 20120231520
    Abstract: The present invention relates to novel Prolipase-Bovine trypsinogen (PLBTR) fusion proteins, the genes encoding them, and the production and uses thereof. More specifically, the present invention relates to methods of producing in optimal quantities PLBTR fusion proteins which comprise a heterologous polypeptide which is normally susceptible to autocatalytic activity. More particularly, the present invention relates to fusion proteins which comprise an heterologous polypeptide, such as a serine protease, fused to a lipase signal sequence, which can be expressed by recombinant host cells in desired amounts. The present invention further relates to polynucleotides encoding such fusion proteins, to expression vectors for expression of such fusion proteins, to host cells transformed with such polynucleotides/vectors, and to methods of generating such fusion proteins.
    Type: Application
    Filed: October 26, 2009
    Publication date: September 13, 2012
    Applicant: BIOCON LIMITED
    Inventors: Nagaraj Govindappa, Nandini Nataraj, Sanjay Tiwari, Partha Hazra, Mukesh Babuappa Patale, Gokul Jothiraman, Kedarnath Sastry