Patents by Inventor Keelnatham Shanmugam

Keelnatham Shanmugam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of using cellulase for reducing the viscosity of feedstock
    Patent number: 9322043
    Abstract: The invention provides methods for treatment of feedstock to reduce the relative viscosity and promote release of fermentable sugars.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: April 26, 2016
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Lonnie O. Ingram, Claudia C. Geddes, James J. Peterson, Michael T. Mullinnix, Keelnatham Shanmugam
  • Ethanologenic bacteria with increased resistance to furfural
    Patent number: 9150887
    Abstract: The invention relates to bacterium that have increased resistance to furfural and methods of preparation. The invention also relates to methods of producing ethanol using the bacterium and corresponding kits.
    Type: Grant
    Filed: January 4, 2010
    Date of Patent: October 6, 2015
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Elliot Norman Miller, Laura R. Jarboe, Lorraine P. Yomano, Sean W. York, Keelnatham Shanmugam, Lonnie O'Neal Ingram
  • Re-engineering bacteria for ethanol production
    Patent number: 8716002
    Abstract: The invention provides recombinant bacteria, which comprise a full complement of heterologous ethanol production genes. Expression of the full complement of heterologous ethanol production genes causes the recombinant bacteria to produce ethanol as the primary fermentation product when grown in mineral salts medium, without the addition of complex nutrients. Methods for producing the recombinant bacteria and methods for producing ethanol using the recombinant bacteria are also disclosed.
    Type: Grant
    Filed: August 8, 2007
    Date of Patent: May 6, 2014
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Lorraine P. Yomano, Sean W. York, Shengde Zhou, Keelnatham Shanmugam, Lonnie O. Ingram
  • Ethanol production in non-recombinant hosts
    Patent number: 8465953
    Abstract: Non-recombinant bacteria that produce ethanol as the primary fermentation product, associated nucleic acids and polypeptides, methods for producing ethanol using the bacteria, and kits are disclosed.
    Type: Grant
    Filed: April 26, 2007
    Date of Patent: June 18, 2013
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Youngnyun Kim, Keelnatham Shanmugam, Lonnie O. Ingram
  • METHODS OF USING CELLULASE FOR REDUCING THE VISCOSITY OF FEEDSTOCK
    Publication number: 20130098356
    Abstract: The invention provides methods for treatment of feedstock to reduce the relative viscosity and promote release of fermentable sugars.
    Type: Application
    Filed: March 10, 2011
    Publication date: April 25, 2013
    Applicant: University of Florida Research Foundation, Inc.
    Inventors: Lonnie O. Ingram, Claudia C. Geddes, James J. Peterson, Michael T. Mullinnix, Keelnatham Shanmugam
  • Materials and methods for the efficient production of acetate and other products
    Patent number: 8383374
    Abstract: The subject invention provides materials and methods wherein unique and advantageous combinations of gene mutations are used to direct carbon flow from sugars to a single product. The techniques of the subject invention can be used to obtain products from native pathways as well as from recombinant pathways. In preferred embodiments, the subject invention provides new materials and methods for the efficient production of acetate and pyruvic acid.
    Type: Grant
    Filed: June 7, 2011
    Date of Patent: February 26, 2013
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Thomas B. Causey, Lonnie O'Neal Ingram, Keelnatham Shanmugam, Shengde Zhou
  • ETHANOLOGENIC BACTERIA AND THEIR USE IN ETHANOL PRODUCTION
    Publication number: 20120077241
    Abstract: The invention relates to bacterium that have increased resistance to furfural and methods of preparation. The invention also relates to methods of producing ethanol using the bacterium and corresponding kits.
    Type: Application
    Filed: January 4, 2010
    Publication date: March 29, 2012
    Applicant: University of Florida Research Foundation, Inc.
    Inventors: Elliot Norman Miller, Laura R. Jarboe, Lorraine P. Yomano, Sean W. York, Keelnatham Shanmugam, Lonnie O'Neil Ingram
  • Materials and methods for the efficient production of acetate and other products
    Patent number: 7977075
    Abstract: The subject invention provides materials and methods wherein unique and advantageous combinations of gene mutations are used to direct carbon flow from sugars to a single product. The techniques of the subject invention can be used to obtain products from native pathways as well as from recombinant pathways. In preferred embodiments, the subject invention provides new materials and methods for the efficient production of acetate and pyruvic acid.
    Type: Grant
    Filed: September 22, 2008
    Date of Patent: July 12, 2011
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Thomas B. Causey, Lonnie O'Neal Ingram, Keelnatham Shanmugam, Shengde Zhou
  • RE-ENGINEERING BACTERIA FOR ETHANOL PRODUCTION
    Publication number: 20100112656
    Abstract: The invention provides recombinant bacteria, which comprise a full complement of heterologous ethanol production genes. Expression of the full complement of heterologous ethanol production genes causes the recombinant bacteria to produce ethanol as the primary fermentation product when grown in mineral salts medium, without the addition of complex nutrients. Methods for producing the recombinant bacteria and methods for producing ethanol using the recombinant bacteria are also disclosed.
    Type: Application
    Filed: August 8, 2007
    Publication date: May 6, 2010
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Lorraine P. Yomano, Sean W. York, Shengde Zhou, Keelnatham Shanmugam, Lonnie O. Ingram
  • ETHANOL PRODUCTION IN NON-RECOMBINANT HOSTS
    Publication number: 20090286293
    Abstract: Non-recombinant bacteria that produce ethanol as the primary fermentation product, associated nucleic acids and polypeptides, methods for producing ethanol using the bacteria, and kits are disclosed.
    Type: Application
    Filed: April 26, 2007
    Publication date: November 19, 2009
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Youngnyun Kim, Keelnatham Shanmugam, Lonnie O. Ingram
  • Materials and methods for efficient lactic acid production
    Publication number: 20070037265
    Abstract: The present invention provides derivatives of ethanologenic Escherichia coli K011 constructed for the production of lactic acid. The transformed E. coli of the invention are prepared by deleting the genes that encode competing pathways followed by a growth-based selection for mutants with improved performance. These transformed E. coli are useful for providing an increased supply of lactic acid for use in food and industrial applications.
    Type: Application
    Filed: August 8, 2006
    Publication date: February 15, 2007
    Applicant: University of Florida Research Foundation, Inc.
    Inventors: Shengde Zhou, Lonnie Ingram, Keelnatham Shanmugam, Lorraine Yomano, Tammy Grabar, Jonathan Moore
  • Production of chemicals from lignocellulose, biomass or sugars
    Publication number: 20050250192
    Abstract: The subject invention relates to newly isolated organisms from nature that produce L(+)-lactic acid high yield from hexose and pentose sugars found in biomass. Organisms and processes or methods for the production of lactic acid and other industrially important chemicals from cellulose and hemicellulose are also provided.
    Type: Application
    Filed: March 4, 2004
    Publication date: November 10, 2005
    Applicant: Univeristy of Florida Research Foundation, Inc.
    Inventors: Keelnatham Shanmugam, Lonnie Ingram, Milind Patel, Mark Ou, Roberta Harbrucker