Abstract: The disclosure provides for improved pharmaceutical compositions containing deferasirox (DFX) and methods of manufacturing the same. In particular, the compositions are prepared using thermokinetic compounding and provide improved properties as well as more efficient methods of manufacture.

Abstract: Provided is a computer-implemented method, system, and computer program product for displaying information to a pedestrian using a visual indicator. A processor may detect that a vehicle is approaching a pedestrian. The processor may determine that the pedestrian is unable to see the approaching vehicle. The processor may display an indication that the vehicle is approaching the pedestrian on an object the pedestrian can currently view.

Abstract: In an approach to improve the generation of a virtual object in a three-dimensional virtual environment, embodiments of the present invention identify a virtual object to be generated in a three-dimensional virtual environment based on a natural language utterance. Additionally, embodiments generate the virtual object based on a CLIP-guided Generative Latent Space (CLIP-GLS) analysis, and monitor usage of the generated virtual object in the three-dimensional virtual space. Moreover, embodiments infer human perception data from the monitoring, and generate a utility score for the virtual object based on the human perception data.

Abstract: A charging system for an aerosol-generating device includes a processor and a memory in communication with the processor and configured to store instructions is provided. The instructions define at least one of a disable mode, an intra-session mode, or an inter-session mode. The processor is configured to execute the instructions to cause the charging system to detect when the device is connected to a charging device; activate a power source charger in response to the connection to the charging device; identify a selected mode; enable or disable a heater of the capsule dependent upon the selected mode; if the heater is enabled, display a first display indicating the connection of the charging device; if the heater is enabled, detect if a session of the aerosol-generating device is ongoing; and if the session is ongoing, enable or suspend charging in response to the identification of the selected mode.

Abstract: The present invention relates to multimers of polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. The invention also describes the multimerization of polypeptides through various chemical linkers and hinges of various lengths and rigidity using different sites of attachments within polypeptides. In particular, the invention describes multimers of peptides which are high affinity binders of ACE2. The invention also includes pharmaceutical compositions comprising said polypeptides and to the use of said polypeptides in suppressing or treating a disease or disorder mediated by ACE2, such as infection of COVID-19 or for providing prophylaxis to a subject at risk of infection of COVID-19.

Abstract: A power control system for an aerosol-generating device includes at least one processor and a memory. The memory is coupled to the at least one processor and is configured to store instructions. The at least one processor is configured to execute the instructions to cause the power control system to determine whether a first power to be applied to a heater of the aerosol-generating device exceeds a power threshold, in response to the first power exceeding the power threshold, apply a second power to the heater, and in response to the first power not exceeding the power threshold, apply the first power to the heater. The first power is based on a desired heater temperature. The second power does not exceed the power threshold.

Abstract: One or more computer processors detect a computing device within a proximity to a rollable device. The one or more computer processors determine a location and an orientation of the rollable device relative to the computing device. The one or more computer processors attach the rollable device to the computing device utilizing the set of biometric locks engaged programmatically such that at least one side of the rollable device is locked and hinged to the computing device. The one or more computer processors responsive to the rollable device attached to a side of the computing device, extend a display area of the computing device to the rollable device.

Abstract: Disambiguation of search keywords to expert systems is performed through the application of a semantic ranking function to determine a classification category with confidence for a given query. The semantic ranking function is executed through an application of a semantic distance distribution profile score through analysis of user problem statement (UPS) with nodes in the taxonomy in the same vector space to create a search that combines a user problem statement and a taxonomical node in the search engine index. The distribution profile score calculation is provenance influenced to derive geographic, cultural, and demographic provenance for a user problem statement.

Abstract: Systems, methods, and computer program products for selectively customizing, modifying and changing performance parameters, capabilities and behaviors of AI devices within AI device networks by sharing user-selected portions of a knowledge corpus with other AI device networks. Selectively sharing parameters, learned behaviors, capabilities, and features of the knowledge corpus allows for AI devices within a second AI device network to mimic, clone or recreate the performance or behaviors of AI devices operating within the environment of a first AI device network. Users can create portable nodes that travel with the user and upon connecting with the second device network, identify AI devices that can be modified using the portions of the knowledge corpus to recreate selected portions of the first AI device network within the environment of the second AI device network either permanently or for a user-selected amount of time.

Abstract: The present invention relates to multimers of polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. The invention also describes the multimerization of polypeptides through various chemical linkers and hinges of various lengths and rigidity using different sites of attachments within polypeptides. In particular, the invention describes multimers of peptides which are high affinity binders of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly the spike protein S1 of SARS-CoV-2. The invention also includes pharmaceutical compositions comprising said polypeptides and to the use of said polypeptides in suppressing or treating a disease or disorder mediated by infection of SARS-CoV-2 or for providing prophylaxis to a subject at risk of infection of SARS-CoV-2.

Abstract: Systems for processing digital media data to reduce the size while maintaining a target perceptual quality. A device may receive an original media for processing to a target Psychovisual Compression Index (PVCI). A device may determine a plurality of Psychovisual Compression (PVC) metrics for the original media. A device may process the original media using a trained neural network to identify psychologically important features of the original media using the plurality of PVC metrics. A device may generate a resized media based on the plurality of PVC metrics and the psychologically important features of the original media, the resized media comprising the psychologically important features of the original media and being a smaller data size compared with the original media. A device may determine a Psychovisual Compression Index (PVCI) for the resized media. A device may compare the resized media to a threshold of the target PVCI.

Abstract: A computer-implemented method, a computer system and a computer program product control participant interaction within remote meeting sessions. The method includes capturing participant data using a device, where the participant data is associated with a participant within the remote meeting session and is selected from a group consisting of: audio data, image data and text data. The method also includes identifying an event in the participant data. The method further includes determining that the participant has not modified a participant interaction mode. Lastly, the method includes modifying the participant interaction mode of the participant when the event is classified as causing a change of the participant interaction mode.

Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of the COVID-19 nucleocapsid protein (N-protein). The invention also includes pharmaceutical compositions comprising said polypeptides and to the use of said polypeptides in suppressing or treating a disease or disorder mediated by the COVID-19 nucleocapsid protein (N-protein), such as infection of COVID-19 or for providing prophylaxis to a subject at risk of infection of COVID-19.

Abstract: Described are mechanisms for multi-nozzle additive manufacturing. The mechanisms include a three-dimensional printer including a primary print head with a primary nozzle. The three-dimensional printer further includes a nozzle print head configured to print different nozzles for additive manufacturing of an object. The three-dimensional printer further includes a secondary nozzle printed by the nozzle print head, and the three-dimensional printer is configured to print the object using the primary print head, the primary nozzle, and the secondary nozzle.

Abstract: Adaptive content delivery systems and methods are disclosed herein. An example system is configured to determine capabilities of a requesting end user system, interface with a database designed to store images characterized by criteria, select an image from the database that balances a highest quality and a smallest file size for the end user system, based on the capabilities, and provide the image to a network for delivery to the end user system.

Abstract: Various techniques are described for platform management of integrated access of public and privately-accessible datasets utilizing federated query generation and query schema rewriting optimization, including receiving at a dataset access platform a query formatted according to a first data schema, generating a copy of the query, saving the query and the copy to a datastore, parsing the copy of the query in the first schema using an inference engine, determining whether the query comprises data associated with an access control condition associated with accessing the dataset, the access control condition being configured to indicate whether the query is permitted to access the dataset, and rewriting, using a proxy server, the copy of the query in a second schema by converting the copy of the query into a triple associated with the query and another triple associated with the access control condition.

Abstract: Methods, systems, and devices for techniques to manufacture inter-layer vias are described. In some examples, a manufacturing process for a via to one or more metal lines within an integrated circuit may not include forming a metal pad for the via. For example, the manufacturing process may include forming a layer of dielectric material over a set of metal lines. The manufacturing process may further include forming a cavity through the dielectric layer (e.g., using an etching procedure), exposing the upper surfaces and sidewalls of one or more metal lines of the set. Subsequently, the via may be formed by depositing a conductive material within the cavity. In some cases, the conductive material may be deposited to contact the sidewalls of the one or more metal lines. Such an assembly may establish electrical connection to other electrical components of the integrated circuit.

Abstract: Determining contextual relevance of images to automatically generate notifications is provided. An analysis of an image is performed using a set of machine learning models. A context of a current environment of a user captured in the image is determined based on the analysis of the image. A comparison of the context of the current environment of the user is performed against the known information stored in the knowledge corpus. An insight corresponding to the user activity is generated based on the comparison of the context of the current environment of the user against the known information stored in the knowledge corpus. The insight identifies a set of interested parties corresponding to the user who are to be notified and provides proactive assistance to the user to automatically generate a notification in real time. The notification is generated containing the insight corresponding to the user activity.

Abstract: A computer-implemented method for airflow control for agricultural pollination is disclosed. The computer-implemented method includes performing image analysis on an agricultural image to determine a type and classification of one or more plants in the agricultural image, determining one or more pollination requirements for the one or more determined plants, determining one or more current airflow parameters within a predetermined area of the one or more plants in the agricultural image, determining one or more optimal airflow parameters based on the type of plants in the agricultural image, the classification of plants in the agricultural image, the one or more pollination requirements for the plants in the agricultural image, and the one or more current airflow parameters, and generating an automatic airflow adjustment model for optimizing the airflow parameters for the plants based, at least in part, on the one or more determined optimal airflow parameters.

Abstract: According to one embodiment, a method, computer system, and computer program product for determining acoustics in a workplace is provided. The present invention may include performing digital twin simulation of sound generation and at least one machine in the workplace; calculating one or more resultant sound fields in the workplace; identifying sound cancellation potential of a worker's sound cancellation protection; and determining if the worker is wearing proper sound cancellation protection based on the one or more resultant sound fields in the workplace and the sound cancellation potential of the worker's sound cancellation protection.