Abstract: Disclosed is an amorphous calcium phosphate gel, as well as a preparation method and use thereof. The method comprises: adding aminomethyl propanol to a propylene glycol solution containing a calcium source to obtain a mixture; slowly adding a phosphoric acid solution to the mixture to obtain the amorphous calcium phosphate gel. The amorphous calcium phosphate gel as provided in the present disclosure has an excellent stability, which shows no obvious phase change after being left at room temperature for 12 months. The method avoids the use of toxic and harmful agents, which allows the production process to be safe and environmentally friendly, and also ensures the safety of the product. The method has a simple process, which allows the large-scale production of the product and provides a basis for the wide application of the amorphous calcium phosphate gel in oral care.

Abstract: A method for making a composition for enamel regeneration proposes to encapsulate soluble calcium and phosphate salts within corresponding internal water phases in respective water-in-oil-in-water emulsions stabilized by solid particles, and add them to a toothpaste, enamel restoring gel or mouth wash base. In this way, the soluble calcium and phosphate salts can be present stably in the toothpaste, enamel restoring gel or mouth wash over a long period of time. When the toothpaste, enamel restoring gel or mouth wash of the present disclosure is used in oral cavity, the water-in-oil-in-water emulsions rapture under the effect of friction and pressing, releasing the soluble calcium and phosphate salts encapsulated within the corresponding internal water phases. As a result, the liquid in the user's oral cavity will contain high concentrations of calcium and phosphate ions, which can enhance the rate of enamel remineralization.

Abstract: A method for making a toothpaste enabling enamel restoration proposes to encapsulate soluble calcium and phosphate salts within corresponding internal water phases in respective water-in-oil-in-water emulsions. In this way, the soluble calcium and phosphate salts can be present stably in the toothpaste over a long period of time without causing precipitation of calcium phosphate. When the toothpaste of the present disclosure is used in brushing teeth, the water-in-oil-in-water emulsions are ruptured under the effect of friction and pressing, releasing the soluble calcium and/or phosphate salts encapsulated within the corresponding internal water phases. As a result, the liquid in the user's oral cavity will contain high concentrations of calcium and phosphate ions, which can enhance the rate of remineralization of enamel and/or dentin exposed to the oral cavity.

Abstract: A method for making a toothpaste enabling enamel restoration proposes to encapsulate soluble calcium and phosphate salts within corresponding internal water phases in respective water-in-oil-in-water emulsions. In this way, the soluble calcium and phosphate salts can be present stably in the toothpaste over a long period of time without causing precipitation of calcium phosphate. When the toothpaste of the present disclosure is used in brushing teeth, the water-in-oil-in-water emulsions are ruptured under the effect of friction and pressing, releasing the soluble calcium and/or phosphate salts encapsulated within the corresponding internal water phases. As a result, the liquid in the user's oral cavity will contain high concentrations of calcium and phosphate ions, which can enhance the rate of remineralization of enamel and/or dentin exposed to the oral cavity.

Abstract: A method for making a composition for enamel regeneration proposes to encapsulate soluble calcium and phosphate salts within corresponding internal water phases in respective water-in-oil-in-water emulsions stabilized by solid particles, and add them to a toothpaste, enamel restoring gel or mouth wash base. In this way, the soluble calcium and phosphate salts can be present stably in the toothpaste, enamel restoring gel or mouth wash over a long period of time. When the toothpaste, enamel restoring gel or mouth wash of the present disclosure is used in oral cavity, the water-in-oil-in-water emulsions rapture under the effect of friction and pressing, releasing the soluble calcium and phosphate salts encapsulated within the corresponding internal water phases. As a result, the liquid in the user's oral cavity will contain high concentrations of calcium and phosphate ions, which can enhance the rate of enamel remineralization.