Patents by Inventor KEHSIN CHIEN

KEHSIN CHIEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Osteoinductive bone graft substitute
    Patent number: 9272072
    Abstract: An osteoinductive bone graft substitute including an osteoinductive calcium phosphate component retained within a collagen scaffold, wherein the collagen scaffold is formulated to maintain the osteoinductivity of the calcium phosphate component while also exhibiting the following characteristics (1) ability to absorb bone marrow and/or other physiologic liquids, (2) compression resistance; (3) moldability; (4) retaining the calcium phosphate component during and after manipulation of the collagen scaffold and (5) fibrous collagen matrix that retains but does not occlude the osteoinductive calcium phosphate component.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: March 1, 2016
    Assignee: NuVasive, Inc.
    Inventors: Ali Ismailoglu, Frank Vizesi, Sung-Ching Chen, Po-Hung Lai, Kehsin Chien
  • Surgical calcium phosphate citrate-containing cement and method of manufacturing the same
    Patent number: 8414930
    Abstract: The present invention discloses a surgical cement and a manufacturing method thereof. The surgical cement comprises a cementing component selected form the group of a basic calcium phosphate consisting of tetracalcium phosphate, alpha-tricalcium phosphate, decomposed hydroxyapatite, or a combination thereof; a setting reagent selected form the group of an acidic calcium citrate consisting of monocalcium citrate, dicalcium citrate, or a combination thereof; and water; wherein a weight ratio of the cementing component and the setting reagent ranges from about 1:1 to about 8:1. The surgical cement is bioresorbable and bioactive and is useful in orthopedic, maxillofacial and dental applications. In addition, the surgical cement of this invention has a good flow character and a relatively short setting time.
    Type: Grant
    Filed: January 11, 2011
    Date of Patent: April 9, 2013
    Assignee: Maxigen Biotech Inc.
    Inventors: Sung-Tsuen Liu, Sung-Ching Chen, Hui-Chun Lai, Kehsin Chien
  • Surgical Calcium Phosphate Citrate-Containing Cement and Method of Manufacturing the Same
    Publication number: 20120178684
    Abstract: The present invention discloses a surgical cement and a manufacturing method thereof. The surgical cement comprises a cementing component selected form the group of a basic calcium phosphate consisting of tetracalcium phosphate, alpha-tricalcium phosphate, decomposed hydroxyapatite, or a combination thereof; a setting reagent selected form the group of an acidic calcium citrate consisting of monocalcium citrate, dicalcium citrate, or a combination thereof; and water; wherein a weight ratio of the cementing component and the setting reagent ranges from about 1:1 to about 8:1. The surgical cement is bioresorbable and bioactive and is useful in orthopedic, maxillofacial and dental applications. In addition, the surgical cement of this invention has a good flow character and a relatively short setting time.
    Type: Application
    Filed: January 11, 2011
    Publication date: July 12, 2012
    Applicant: MAXIGEN BIOTECH INC.
    Inventors: SUNG-TSUEN LIU, SUNG-CHING CHEN, HUI-CHUN LAI, KEHSIN CHIEN