Abstract: As a thermoplastic resin used as a matrix resin for a fiber-reinforced composite material, a thermoplastic resin having a high glass transition temperature in spite of having a low resin viscosity during molding is provided. Provided are a two-liquid curable composition for forming a thermoplastic matrix resin, the two-liquid curable composition containing an active hydrogen component containing an alkylthio group-containing aromatic diamine (A) and a diisocyanate component containing at least one kind of diisocyanate (B) selected from the group consisting of aliphatic diisocyanates, alicyclic diisocyanates, and modified forms of aliphatic diisocyanates and alicyclic diisocyanates, a matrix resin for a fiber-reinforced composite material, the matrix resin being a thermoplastic resin containing a reaction product of the active hydrogen component and the diisocyanate component, and a fiber-reinforced composite material containing the matrix resin and reinforcing fiber.

Abstract: Compounds or salts thereof represented by formula (I): wherein X indicates a leaving group, Y indicates an affinity peptide having a binding region in a CH2 domain in an immunoglobulin unit comprising two heavy chains and two light chains, M indicates a trivalent group linking the carbon atom in C?O adjacent to M and the carbon atom in C?W via a main chain portion consisting of 3 to 5 carbon atoms, O indicates an oxygen atom, S indicates a sulfur atom, W indicates an oxygen atom or a sulfur atom, N3 indicates an azide group, La indicates a bond or a divalent group, and Lb indicates a bond or a divalent group; and antibodies or salts thereof which can be prepared using such a compound or salt thereof, are useful for controlling the bonding ratio of an antibody and a modifying group within a desired range.

Abstract: A cover member configured to cover a drive-power transmission member is fixed to a swing arm with a simple structure. A saddle-ride type vehicle includes a swing arm swingable up and down, a rear wheel supported at a rear end portion of the swing arm, an endless drive-power transmission member extending along the swing arm in a front-rear direction and configured to transmit drive power of a power unit to the rear wheel, a cover member fixed to the swing arm and covering the drive-power transmission member, and a slider provided on an upper face of the swing arm and configured to receive the drive-power transmission member. The cover member includes a fastening portion that is fastened to the swing arm by a fastener and an engagement portion that engages with the slider.

Abstract: The present invention provides a highly controlled complex comprising an antibody and ferritin particles. More specifically, the present invention provides the inventions of a complex or salt thereof comprising (A) one IgG antibody and (B) two human ferritin particles comprising one or more human ferritin H chains linked thereto; and methods for producing the same.

Abstract: Compounds and salts thereof represented by the following formula (I): wherein X indicates a leaving group, Y indicates an affinity peptide having a binding region to a CH2 domain in an immunoglobulin unit containing two heavy chains and two light chains, O indicates an oxygen atom, S indicates a sulfur atom, W indicates an oxygen atom or a sulfur atom, La indicates a first linker, Lb indicates a second linker, and the total number of atoms constituting a main chain in the first linker and atoms constituting a main chain in the second linker are 5 to 7, facilitate regioselective modification of an antibody with a functional substance and control of the bonding ratio of the antibody to the functional substance within a desired range.

Abstract: A desired antibody or antibody composition may be obtained by modifying a thiol group chemically introduced to an antibody to obtain an antibody composition comprising (A) an antibody intermediate or a salt thereof having a bioorthogonal functional group which may be protected, which is represented by the following formula (A): AbS-L-R]n??(A) wherein Ab is a certain antibody, S is a sulfur atom, L is a divalent group, R is a bioorthogonal functional group which may be protected, and n is an integer from 1 to 8, and (B) a thiol group-introduced antibody or a salt thereof, which is represented by the following formula (B): AbSH]n??(B) wherein Ab and n are the same as formulae (A), and SH is a thiol group; and the like.

Abstract: Provided is a vehicular control device that is provided with a switching circuit, and for opening/closing a connection between a starter including a capacitor that is to be connected to one end portion of the switching circuit and an in-vehicle battery that is to be connected to another end portion of the switching circuit by controlling an on/off state of the switching circuit. The control device includes a voltage detection unit configured to detect a voltage of the one end portion, and a control unit configured to control the switching circuit to turn off from on, and determine whether there is a failure in the switching circuit, based on a voltage detected by the voltage detection unit when a predetermined time has elapsed from when the switching circuit is controlled to turn off from on.

Abstract: Controlling the number of modifying groups introduced into a surface of ferritin affords a modified ferritin containing a human ferritin H chain, in which the human ferritin H chain contains a modifying group that is covalently bonded specifically to a cysteine residue at position 91 and/or position 103 according to a reference position of a natural human ferritin H chain.

Abstract: Provided is a vehicular control device that is provided with a switching circuit, and for opening/closing a connection between a starter including a capacitor that is to be connected to one end portion of the switching circuit and an in-vehicle battery that is to be connected to another end portion of the switching circuit by controlling an on/off state of the switching circuit. The control device includes a voltage detection unit configured to detect a voltage of the one end portion, and a control unit configured to control the switching circuit to turn off from on, and determine whether there is a failure in the switching circuit, based on a voltage detected by the voltage detection unit when a predetermined time has elapsed from when the switching circuit is controlled to turn off from on.

Abstract: Compounds having an affinity substance to an antibody, a cleavable portion, and a reactive group, or a salt thereof, are represented by the following Formula (I): A-L-B—R??(I) wherein A is an affinity substance to an antibody, L is a cleavable linker that is a divalent group comprising a cleavable portion, B is (a) a divalent group comprising a bioorthogonal functional group or (b) a divalent group comprising no bioorthogonal functional group, and R is a reactive group to the antibody, wherein the affinity substance to an antibody is a polypeptide comprising a glutamine residue (Q) at an N-terminal.

Abstract: Compounds having an affinity substance to an antibody and a bioorthogonal functional group, represented by the following Formula (I): A-L-E-B??(I) wherein A is an affinity substance to an antibody, L is a divalent group comprising a leaving group, E is a divalent group comprising an electrophilic group (i) coupled with the leaving group and (ii) having ability to react with a nucleophilic group in the antibody, B is a bioorthogonal functional group, and the leaving group has ability to be cleaved and eliminated from E by a reaction between the nucleophilic group and the electrophilic group, or a salt thereof, and the like are useful for labelling antibodies.

Abstract: Compounds having an affinity substance to an antibody, a cleavable portion, and a reactive group, represented by the following Formula (I): A-L-B-R??(I) wherein A is the affinity substance an antibody, L is a cleavable linker which is a divalent group comprising the cleavable portion, B is (a) a divalent group comprising a bioorthogonal functional group or (b) a divalent group comprising no bioorthogonal functional group, and R is the reactive group to the antibody, in which the affinity substance to an antibody is a certain peptide, or a salt thereof are useful for the modification of an antibody, particularly the regioselective modification of an antibody.

Abstract: The present invention provides a technique enabling modification of a soluble protein and in particular regioselective modification of a soluble protein. More specifically, the present invention provides a compound having an affinity substance to a soluble protein, a cleavable portion, and a reactive group represented by the following Formula (I): A-L-B-R??(I) wherein A is an affinity substance to a soluble protein; L is a cleavable linker which is a divalent group comprising a cleavable portion; B is (a) a divalent group comprising a bioorthogonal functional group or (b) a divalent group comprising no bioorthogonal functional group; and R is a reactive group to the soluble protein; or a salt thereof.

Abstract: In a microcomputer provided in a power supply control device, an output circuit outputs a PWM signal, in the case where a control unit determines that the value of a switch current that flows via a semiconductor switch is less than a current threshold value. In the case where the control unit determines that the switch current value is equal to or greater than the current threshold value, the output circuit outputs a switch signal output by an output unit. The switch signal instructs ON or OFF of the semiconductor switch. A drive circuit switches the semiconductor switch to ON or OFF, based on the PWM signal or switch signal output by the output circuit.

Abstract: A slotted-type rigid coupling is manufactured so that the internal-diameter dimension of a first shaft hole of a circumferentially divided shaft-fastening part is the same as that of a shaft. The first shaft hole is widened by widening force from a pressing mechanism provided with a fastening bolt, and the shaft is inserted through the first shaft hole up to a shaft insertion hole. The widening force is ceased, the first shaft hole is narrowed by fastening force from the pressing mechanism, and the shaft is securely fastened. When the shaft is securely fastened to the shaft-fastening part by the fastening bolt, eccentricity in the shaft is prevented or minimized.

Abstract: An image processing linkage system includes: an image processing apparatus and a portable terminal device connectable with each other, wherein the image processing apparatus includes a display unit, and a transmitting unit, the portable terminal device includes a display unit, a receiving unit, a display control unit, an operation information converting unit, and a transmitting unit, and the image processing apparatus receives the operation information transmitted from the portable terminal device, and executes a process corresponding to the operation information.

Abstract: An allocation apparatus configured to allocate a plurality of information processing devices to two or more management apparatuses that perform distributed management of the plurality of information processing devices, the allocation apparatus includes: an allocation unit configured to allocate an address range on a network, allocatable to a plurality of information processing devices, to the two or more management apparatuses; and an acquisition unit configured to obtain, from each of the two or more management apparatuses, management information indicating a state of the information processing device whose address belongs to a range allocated to the management apparatus, wherein the allocation unit dynamically performs allocation of the address range on the network based on the management information that has been obtained by the acquisition unit.

Abstract: An allocation apparatus configured to allocate a plurality of information processing devices to two or more management apparatuses that perform distributed management of the plurality of information processing devices, the allocation apparatus includes: an allocation unit configured to allocate an address range on a network, allocatable to a plurality of information processing devices, to the two or more management apparatuses; and an acquisition unit configured to obtain, from each of the two or more management apparatuses, management information indicating a state of the information processing device whose address belongs to a range allocated to the management apparatus, wherein the allocation unit dynamically performs allocation of the address range on the network based on the management information that has been obtained by the acquisition unit.

Abstract: When a first remote panel accepts an operation to move a display screen, the first remote panel transmits information on the operation to a relay server. The relay server determines a destination display screen based on the received information, and transmits information on the destination display screen to each of an MFP (Multifunction Peripheral), the first remote panel, and a second remote panel. The relay server transmits data on the destination display screen to each of the first and second remote panels. After transmitting the information on the destination display screen, the relay server receives data on a neighboring screen of the destination display screen from the MFP.

Abstract: An image processing linkage system includes: an image processing apparatus and a portable terminal device connectable with each other, wherein the image processing apparatus includes a display unit, and a transmitting unit, the portable terminal device includes a display unit, a receiving unit, a display control unit, an operation information converting unit, and a transmitting unit, and the image processing apparatus receives the operation information transmitted from the portable terminal device, and executes a process corresponding to the operation information.