Abstract: Methods and compositions are provided for the treatment and diagnosis of diseases related to hyperglycemic conditions, including diabetes, insulin resistance, and the like. Genetic polymorphisms are shown to be associated with disease susceptibility, and their detection is used in the diagnosis of a predisposition to these conditions. The corresponding proteins are useful as targets for therapeutic intervention.

Abstract: A reinforced hose has an inner tube made of rubber, an inner reinforcing layer made of aromatic polyamide yarn formed on the inner tube, an intermediate layer made of rubber formed on the inner reinforcing layer, an outer reinforcing layer made of synthetic yarn formed on the intermediate layer which has a heat shrinkage ratio at dried condition of over about 0.5% due to the temperature of a curing process, and a covering layer made of rubber being formed on the outer reinforcing layer. By providing the inner reinforcing layer of aromatic polyamide yarn, the reinforced hose of the present invention has a high stretching strength. Furthermore, by making the outer reinforcing layer of synthetic yarn, which has a heat shrinkage ratio at dried condition of over about 0.5% due to the temperature of a curing process, the reinforced hose of the present invention can hardly be expanded by the pressure of inside fluid.

Abstract: Disclosed is a hose unit including harnesses which can be easily attached to and detached from the other portion of the unit at the time of fastening thereof to the body of a motor vehicle or the like and which hardly undergoes stress even at the time of vibration or torsion of the hose of the unit. The hose unit includes the hose to which respective end metal members are secured. Holders are removably fastened to these members. One harness extends along the hose and is fastened to the holders and another harness is connected to the former through the holders and extends therefrom. Also disclosed is a special hose clamp.

Abstract: A hydraulic brake hose has an inner tube made of nylon, an isocyanate adhesive layer formed on the outer surface of the inner tube, a chloroprene-rubber adhesive layer formed on the outer surface of the isocyanate adhesive layer, a reinforcing fiber layer made of high polymeric material selected from the group consisting of rayon, polyester, polyamid and polyvinyl alcohol, impregnated with resorcinol formaldehyde latex containing chloroprene-rubber and formed on the outer surface of the chloroprene-rubber adhesive layer and an outer tube made of chloroprene-rubber and formed on the outer surface of the reinforcing fiber layer. The inner tube has the modulus of elasticity of 7,000 to 15,000 kg/cm.sup.2 and has an inner diameter of not less than 2.0 mm, an outer diameter of not more than 6.0 mm and a thickness of not less than 0.7 mm.