Patents by Inventor Keiichi Ohshima

Keiichi Ohshima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220389517
    Abstract: An object of the present invention is to provide a method for predicting a risk of developing cancer. DNA samples were prepared from blood and cancer tissues of 2480 cancer patients and analyzed for the nucleotide sequences of exon regions using NGS. As a result, among the cancer patients, 7 patients were confirmed to have D49H mutation or A159D mutation which is a germ cell mutation.
    Type: Application
    Filed: July 26, 2022
    Publication date: December 8, 2022
    Inventors: Ken YAMAGUCHI, Masatoshi KUSUHARA, Masakuni SERIZAWA, Tohru MOCHIZUKI, Keiichi OHSHIMA, Keiichi HATAKEYAMA, Kenichi URAKAMI, Shumpei OHNAMI, Yasuto AKIYAMA, Kouji MARUYAMA, Kengo INOUE, Yuji SHIMODA, Takeshi NAGASHIMA, Yoshinobu ISHIKAWA
  • Publication number: 20200255901
    Abstract: An object of the present invention is to provide a method for predicting a risk of developing cancer. DNA samples were prepared from blood and cancer tissues of 2480 cancer patients and analyzed for the nucleotide sequences of exon regions using NGS. As a result, among the cancer patients, 7 patients were confirmed to have D49H mutation or A159D mutation which is a germ cell mutation.
    Type: Application
    Filed: August 3, 2017
    Publication date: August 13, 2020
    Inventors: Ken YAMAGUCHI, Masatoshi KUSUHARA, Masakuni SERIZAWA, Tohru MOCHIZUKI, Keiichi OHSHIMA, Keiichi HATAKEYAMA, Kenichi URAKAMI, Shumpei OHNAMI, Yasuto AKIYAMA, Kouji MARUYAMA, Kengo INOUE, Yuji SHIMODA, Takeshi NAGASHIMA, Yoshinobu ISHIKAWA
  • Patent number: 10641773
    Abstract: An object of the present invention is to provide a method for collecting highly accurate data for diagnosis, useful in diagnosing the presence or absence of extrahepatic bile duct carcinoma, intrahepatic bile duct carcinoma, or gallbladder carcinoma, and a kit for diagnosis. When the concentration of CEACAM1 in a blood sample collected from a test subject is detected using a kit for diagnosis comprising an antibody specifically binding to CEACAM1 or a labeled product thereof, or the like and the CEACAM1 concentration is higher than the concentration of CEACAM1 in a blood sample derived from a non-carcinoma control subject or higher than a certain threshold value (cutoff value), data can be collected for diagnosing the test subject as having a high possibility of having extrahepatic bile duct carcinoma, intrahepatic bile duct carcinoma, or gallbladder carcinoma.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: May 5, 2020
    Assignee: SHIZUOKA PREFECTURE
    Inventors: Tohru Mochizuki, Keiichi Ohshima, Keiichi Hatakeyama, Ken Yamaguchi, Kanako Nakao
  • Publication number: 20180080935
    Abstract: An object of the present invention is to provide a method for collecting highly accurate data for diagnosis, useful in diagnosing the presence or absence of extrahepatic bile duct carcinoma, intrahepatic bile duct carcinoma, or gallbladder carcinoma, and a kit for diagnosis. When the concentration of CEACAM1 in a blood sample collected from a test subject is detected using a kit for diagnosis comprising an antibody specifically binding to CEACAM1 or a labeled product thereof, or the like and the CEACAM1 concentration is higher than the concentration of CEACAM1 in a blood sample derived from a non-carcinoma control subject or higher than a certain threshold value (cutoff value), data can be collected for diagnosing the test subject as having a high possibility of having extrahepatic bile duct carcinoma, intrahepatic bile duct carcinoma, or gallbladder carcinoma.
    Type: Application
    Filed: July 21, 2017
    Publication date: March 22, 2018
    Inventors: Tohru MOCHIZUKI, Keiichi OHSHIMA, Keiichi HATAKEYAMA, Ken YAMAGUCHI, Kanako NAKAO
  • Patent number: 6164767
    Abstract: A tube pump for an ink jet printer includes a driving wheel that is selectively driven in a forward or reverse direction in accordance with the rotation of a drive source. The driving wheel contains two slots that extend symmetrically and radially from the center of the driving wheel. The pump also includes two rollers that are coupled to the drive wheel via roller shafts respectively extending from a radial center of the rollers into the slots. A pressing piece is also provided that forces the shafts into the radially outermost end of the slots to press a tube of the tube pump when said drive wheel rotates in reverse and forces the shafts into the radially innermost end of the slots to not press the tube when said drive wheel rotates in the forward direction. In an alternative arrangement, the tube pump contains a pump chamber, and a tube having an .alpha.-like-shaped loop portion is inserted into and disposed along the inner wall of the pump chamber.
    Type: Grant
    Filed: July 14, 1999
    Date of Patent: December 26, 2000
    Assignee: Seiko Corporation
    Inventors: Masahiro Nakamura, Hayato Nishikaze, Nobuhito Takahashi, Seiji Mochizuki, Kazuhisa Kawakami, Keiichi Ohshima, Satoshi Fujioka
  • Patent number: 6106098
    Abstract: First and second cap members seal nozzle openings of first and second ink jet recording heads and are disposed on a side of a slider facing the nozzle openings. The slider is rotatably supported at the center portion in the longitudinal direction by a supporting member which is rotatable about a rotation shaft elongated in a direction perpendicular to the moving direction of the carriage, and which is vertically movable in accordance with the movement of the carriage. When the carriage is moved, the slider swings about the shaft in a manner similar to a seesaw, whereby the two cap members are sequentially fitted into the recording heads.
    Type: Grant
    Filed: May 19, 1997
    Date of Patent: August 22, 2000
    Assignee: Seiko Epson Corporation
    Inventors: Masahiro Nakamura, Hayato Nishikaze, Nobuhito Takahashi, Seiji Mochizuki, Kazuhisa Kawakami, Keiichi Ohshima, Satoshi Fujioka
  • Patent number: 6045207
    Abstract: An ink tank cartridge is provided removably mountable onto an ink supply needle of the ink-jet type recording apparatus body. The cartridge has a housing provided with an ink supply port extending through and projecting from a wall of the housing and into the chamber of the housing. A porous member having ink impregnated thereon is positioned inside the chamber of the housing abutting against the ink supply port. A filter is mounted on the inner end opening of the ink supply port. The ink tank cartridge is further provided with a packing member for resiliently abutting against the outer periphery of the ink supply needle and is positioned adjacent one end of the ink supply port. The outer opening of the ink supply port is sealed with a sealing member through which the ink supply needle penetrates.
    Type: Grant
    Filed: April 25, 1997
    Date of Patent: April 4, 2000
    Assignee: Seiko Epson Corporation
    Inventors: Seiji Mochizuki, Kazuhisa Kawakami, Masahiro Nakamura, Keiichi Ohshima, Masanori Yoshida
  • Patent number: 6019450
    Abstract: An ink jet recording apparatus which includes a recording head communicated via an ink supply needle with an ink tank and including electrodes for detecting a remaining amount of ink and being responsive to a print signal for spouting ink drops to recording paper, a capping unit abutting against the front of said recording head for holding the nozzle openings in an airtight state, a suction pump for supplying negative pressure to the capping unit, a resistance value detection circuit for detecting electric resistance across the electrodes for detecting a remaining amount of ink, a reference value storage unit for storing a resistance value across the electrodes relative to the remaining amount of ink in the ink tank, a resistance value comparison unit for comparing the resistance across the electrodes with the reference value, and a pump control unit responsive to the resistance value comparison result for controlling a pulse motor driving the suction pump.
    Type: Grant
    Filed: December 3, 1996
    Date of Patent: February 1, 2000
    Assignee: Seiko Epson Corporation
    Inventors: Seiji Mochizuki, Kazuhisa Kawakami, Masahiro Nakamura, Keiichi Ohshima
  • Patent number: 5988635
    Abstract: A sheet transporting device includes a drive roller including a high rigidity roller having a surface coated with ceramic particles and a follower roller including an elastic roller having a surface coated with a low friction material. A sheet of printing medium is nipped and fed by the drive roller and the transporting roller.
    Type: Grant
    Filed: October 22, 1997
    Date of Patent: November 23, 1999
    Assignee: Seiko Epson Corporation
    Inventor: Keiichi Ohshima
  • Patent number: 5844578
    Abstract: An ink tank cartridge is provided removably mountable onto an ink supply needle of the ink-jet type recording apparatus body. The cartridge has a housing provided with an ink supply port extending through and projecting from a wall of the housing and into the chamber of the housing. A porous member having ink impregnated thereon is positioned inside the chamber of the housing abutting against the ink supply port. A filter is mounted on the inner end opening of the ink supply port. The ink tank cartridge is further provided with a packing member for resiliently abutting against the outer periphery of the ink supply needle and is positioned adjacent one end of the ink supply port. The outer opening of the ink supply port is sealed with a sealing member through which the ink supply needle penetrates.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 1, 1998
    Assignee: Seiko Epson Corporation
    Inventors: Seiji Mochizuki, Kazuhisa Kawakami, Masahiro Nakamura, Keiichi Ohshima, Masanori Yoshida
  • Patent number: 5793391
    Abstract: An ink-jet recording apparatus includes: an ink-jet recording head; a carriage on which the ink-jet recording head is mounted, the carriage being capable of traveling between a printing and a non-printing area, the carriage having an operating lever on non-printing area thereof; and a wiper for wiping the ink-jet recording head in the non-printing area, the wiper having a projected piece including two tilted sides, the tilted sides being projecting toward the passage in which the carriage moves when the wiper is set in position where the wiper is capable of wiping, wherein, while the carriage is moved in the directions of printing and non-printing area of the carriage, the operating lever comes in contact with the projected piece of the wiping lever so as to move the wiping means out of the traveling passage of the carriage.
    Type: Grant
    Filed: August 11, 1995
    Date of Patent: August 11, 1998
    Assignee: Seiko Epson Corporation
    Inventors: Kazuhisa Kawakami, Keiichi Ohshima, Satoshi Fujioka, Seiji Mochizuki, Masahiro Isono, Atsushi Kobayashi
  • Patent number: 5657058
    Abstract: An ink tank cartridge is provided removably mountable onto an ink supply needle of the ink-jet type recording apparatus body. The cartridge has a housing provided with an ink supply port extending through and projecting from a wall of the housing and into the chamber of the housing. A porous member having ink impregnated thereon is positioned inside the chamber of the housing abutting against the ink supply port. A filter is mounted on the inner end opening of the ink supply port. The ink tank cartridge is further provided with a packing member for resiliently abutting against the outer periphery of the ink supply needle and is positioned adjacent one end of the ink supply port. The outer opening of the ink supply port is sealed with a sealing member through which the ink supply needle penetrates.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: August 12, 1997
    Assignee: Seiko Epson Corporation
    Inventors: Seiji Mochizuki, Kuzuhisa Kawakami, Masahiro Nakamura, Keiichi Ohshima, Masanori Yoshida
  • Patent number: 5606353
    Abstract: An ink jet recording apparatus which includes a recording head communicated via an ink supply needle with an ink tank and including electrodes for detecting a remaining amount of ink and being responsive to a print signal for spouting ink drops to recording paper, a capping unit abutting against the front of said recording head for holding the nozzle openings in an airtight state, a suction pump for supplying negative pressure to the capping unit, a resistance value detection circuit for detecting electric resistance across the electrodes for detecting a remaining amount of ink, a reference value storage unit for storing a resistance value across the electrodes relative to the remaining amount of ink in the ink tank, a resistance value comparison unit for comparing the resistance across the electrodes with the reference value, and a pump control unit responsive to the resistance value comparison result for controlling a pulse motor driving the suction pump.
    Type: Grant
    Filed: March 9, 1994
    Date of Patent: February 25, 1997
    Assignee: Seiko Epson Corporation
    Inventors: Seiji Mochizuki, Kazuhisa Kawakami, Masahiro Nakamura, Keiichi Ohshima
  • Patent number: 5590510
    Abstract: An ink tank cartridge is provided removably mountable onto an ink supply needle of the ink-jet type recording apparatus body. The cartridge has a housing provided with an ink supply port extending through and projecting from a wall of the housing and into the chamber of the housing. A porous member having ink impregnated thereon is positioned inside the chamber of the housing abutting against the ink supply port. A filter is mounted on the inner end opening of the ink supply port. The ink tank cartridge is further provided with a packing member for resiliently abutting against the outer periphery of the ink supply needle and is positioned adjacent one end of the ink supply port. The outer opening of the ink supply port is sealed with a sealing member through which the ink supply needle penetrates.
    Type: Grant
    Filed: April 17, 1995
    Date of Patent: January 7, 1997
    Assignee: Seiko Epson Corporation
    Inventors: Seiji Mochizuki, Kuzuhisa Kawakami, Masahiro Nakamura, Keiichi Ohshima, Masanori Yoshida
  • Patent number: 5576749
    Abstract: An ink tank cartridge is provided removably mountable onto an ink supply needle of the ink-jet type recording apparatus body. The cartridge has a housing provided with an ink supply port extending through and projecting from a wall of the housing and into the chamber of the housing. A porous member having ink impregnated thereon is positioned inside the chamber of the housing abutting against the ink supply port. A filter is mounted on the inner end opening of the ink supply port. The ink tank cartridge is further provided with a packing member for resiliently abutting against the outer periphery of the ink supply needle and is positioned adjacent one end of the ink supply port. The outer opening of the ink supply port is sealed with a sealing member through which the ink supply needle penetrates.
    Type: Grant
    Filed: April 17, 1995
    Date of Patent: November 19, 1996
    Assignee: Seiko Epson Corproation
    Inventors: Seiji Mochizuki, Kuzuhisa Kawakami, Masahiro Nakamura, Keiichi Ohshima, Masanori Yoshida
  • Patent number: 5488401
    Abstract: An ink tank cartridge is provided removably mountable onto an ink supply needle of the ink-jet type recording apparatus body. The cartridge has a housing provided with an ink supply port extending through and projecting from a wall of the housing and into the chamber of the housing. A porous member having ink impregnated thereon is positioned inside the chamber of the housing abutting against the ink supply port. A filter is mounted on the inner end opening of the ink supply port. The ink tank cartridge is further provided with a packing member for resiliently abutting against the outer periphery of the ink supply needle and is positioned adjacent one end of the ink supply port. The outer opening of the ink supply port is sealed with a sealing member through which the ink supply needle penetrates.
    Type: Grant
    Filed: August 11, 1992
    Date of Patent: January 30, 1996
    Assignee: Seiko Epson Corporation
    Inventors: Seiji Mochizuki, Kazuhisa Kawakami, Masahiro Nakamura, Keiichi Ohshima, Masanori Yoshida
  • Patent number: 5477963
    Abstract: An ink tank cartridge is provided removably mountable onto an ink supply needle of the ink-jet type recording apparatus body. The cartridge has a housing provided with an ink supply port extending through and projecting from a wall of the housing and into the chamber of the housing. A porous member having ink impregnated thereon is positioned inside the chamber of the housing abutting against the ink supply port. A filter is mounted on the inner end opening of the ink supply port. The ink tank cartridge is further provided with a packing member for resiliently abutting against the outer periphery of the ink supply needle and is positioned adjacent one end of the ink supply port. The outer opening of the ink supply port is sealed with a sealing member through which the ink supply needle penetrates.
    Type: Grant
    Filed: November 23, 1993
    Date of Patent: December 26, 1995
    Assignee: Seiko Epson Corporation
    Inventors: Seiji Mochizuki, Kuzuhisa Kawakami, Masahiro Nakamura, Keiichi Ohshima, Masanori Yoshida
  • Patent number: 5343229
    Abstract: An ink jet printer, including a gap regulating member that can forward a recording medium correctly by causing the recording medium to approach a recording head as closely as possible involving minimal parts. An upper surface of the gap regulating member serves as a surface for guiding travel of an ink jet head and a lower surface thereof serves as a surface for guiding a recording medium. The gap regulating member is disposed adjacent to a start end of an upwardly rotating region on a sheet feed roller in such a manner that the gap regulating member intersects a circumferential surface of the sheet feed roller at a small angle.
    Type: Grant
    Filed: June 17, 1992
    Date of Patent: August 30, 1994
    Assignee: Seiko Epson Corporation
    Inventor: Keiichi Ohshima
  • Patent number: 5141344
    Abstract: A sheet feeding mechanism for a printing apparatus capable of achieving accurate sheet feed performance free from slanted sheet feeding, dislocation between pages in printing on copy sheets, out-of-pitch printing, and the like. The sheet feeding mechanism includes a pair of confronting roller units capable not only of applying a driving-like sheet feed force to both front and back surfaces of a copy sheet, but also of maintaining a constant pressure contact force from each roller. The shafts of the pair of confronting roller units are driven so that the sheet feed force is stable. The pressure contact force is produced by a structure wherein each roller is biased by independent loading.
    Type: Grant
    Filed: August 12, 1991
    Date of Patent: August 25, 1992
    Assignee: Seiko Epson Corporation
    Inventors: Kenjiro Murakami, Keiichi Ohshima
  • Patent number: 5098211
    Abstract: A sheet feeding mechanism for a serial printing apparatus capable of achieving accurate sheet feed performance free from slanted sheet feeding, dislocation between pages in printing on copy sheets, out-of-pitch, and the like. The sheet feeding mechanism includes a platen for receiving a bias force from a print head, first and second guide plates of the platen, first and second pairs of sheet feed rollers disposed outside the guide plates, a sheet guide member secured to move together with the print head, and a mechanism for elastically biasing a portion of the sheet guide member which confronts the platen onto the platen at all times. The first and second guide plates are positioned so as to be substantially coplanar with a print region of the platen, wherein one of the guide plates is positioned before the platen in the path of a sheet and the other guide plate is positioned after the platen in the path of a sheet.
    Type: Grant
    Filed: January 24, 1991
    Date of Patent: March 24, 1992
    Assignee: Seiko Epson Corporation
    Inventors: Kenjiro Murakami, Keiichi Ohshima