Abstract: A novel carbonate compound represented by the general formula ?I!:R.sup.1 CH.sub.2 O--CO--OCH.sub.2 R.sup.2 ?I!wherein R.sup.1 represents a hydrogen atom, an alkyl group or an alkyl group substituted with one or more halogen atoms, and R.sup.2 represent an alkyl group having no hydrogen atom at the .alpha.-position thereof or an alkyl group substituted with one or more halogen atoms having no hydrogen atom at the .alpha.-position thereof, with the proviso that R.sup.1 is not identical to R.sup.2, which has excellent properties as solvent, is disclosed. A non-aqueous electrolytic solution and a battery utilizing the novel carbonate compound are also disclosed.

Abstract: The present invention relates to a process for producing a transglutaminase, which comprises incubating Escherichia coli expressing genes encoding a heat shock protein (DnaJ) and a transglutaminase. The transglutaminase is produced in large quantities, at low cost and has the appropriate stereostructure to render the transglutaminase biologically active. The transglutaminase so produced is useful in the food industry.

Abstract: A novel carbonate compound represented by the general formula [I]:R.sup.1 CH.sub.2 O--CO--OCH.sub.2 R.sup.2 [I]wherein R.sup.1 represents a hydrogen atom, an alkyl group or an alkyl group substituted with one or more halogen atoms, and R.sup.2 represents an alkyl group having no hydrogen atom at the .alpha.-position thereof or an alkyl group substituted with one or more halogen atoms having no hydrogen atom at the .alpha.-position thereof, with the proviso that R.sup.1 is not identical to R.sup.2, which has excellent properties as solvent, is disclosed. A non-aqueous electrolytic solution and a battery utilizing the novel carbonate compound are also disclosed.

Abstract: A novel carbonate compound represented by the general formula [I]:R.sup.3 CH.sub.2 O-CO-OCH.sub.2 R.sup.4 [I]wherein R.sup.3 represents an alkyl group or an alkyl group substituted with one or more halogen atoms, and R.sup.4 represent an alkyl group having no hydrogen atom at the .beta.-position thereof or an alkyl group substituted with one or more halogen atoms having no hydrogen atom at the .beta.-position thereof, with the proviso that R.sup.3 is not identical to R.sup.4, which has excellent properties as solvent, is disclosed. A non-aqueous electrolytic solution and a battery utilizing the novel carbonate compound are also disclosed.

Abstract: A non-aqueous electrolytic solutions which has self-distinguishing property, low reactivity to metal lithium and high withstand voltage is provided. The non-aqueous electrolytic solutions of the first invention comprise, as electrolyte, lithium salt preferably LiPF.sub.6 and, as solvent, phosphoric acid esters of the following general formula [1]; ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, represent an alkyl group or an alkyl group substituted by one or more halogen atoms and at least one of R.sup.1, R.sup.2, and R.sup.3 represents an alkyl group substituted by one or more halogen atoms. The non-aqueous electrolytic solutions of the second invention comprise, as solvents for electrolyte, trimethyl phosphate, one or more linear carbonates represented by the following general formula [3]; ##STR2## (wherein R.sup.6 represents methyl or ethyl group and R.sup.

Abstract: A secondary battery having a non-aqueous electrolyte according to the present invention includes a negative electrode using a carbonaceous material capable of doping and undoping lithium ions as the anode material, a positive electrode using a composite oxide of lithium and-a transition metal as the cathode material, and a non-aqueous electrolyte formed by dissolving an electrolyte into a non-aqueous solvent, the non-aqueous solvent containing methylethyl carbonate and dimethyl carbonate. According to the present invention, a secondary battery having a non-aqueous electrolyte in which normal charge/discharge reactions can be maintained even in battery overcharge and after high-temperature storage of the charged battery, and which exhibits high energy density, long cycle life, high safety performance and excellent environment-resistance, can be produced.

Abstract: Disclosed are a solvent for cell electrolyte comprising a carbamate represented by the following formula [1]; ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 independently represent a linear or branched alkyl group, cell electrolyte and non-aqueous electrolyte battery comprising the solvent. The solvent can provide batteries showing high withstand voltage and excellent charge/discharge efficiency.

Abstract: Disclosed is a method for producing an angiotensin converting enzyme inhibitor composition from natural materials, which composition is of use as an antihypertensive drug or diet. The method comprises heating a meat in water at a temperature not lower than 50.degree. C. to extract water-soluble protein and hydrolyzing the residue predominantly composed of water-insoluble protein with a protease.

Abstract: A method of producing an angiotensin converting enzyme inhibitor-containing composition, which is of value as an antihypertensive agent or diet, from natural resources. According to the method, proteins are hydrolyzed with a protease elaborated by a microorganism of the genus Bacillus, Aspergillus or Rhizopus or a protease of papaya origin.

Abstract: This invention provides novel pyrimidines or their pharmaceutically acceptable salts thereof and process for preparation thereof. The novel compounds are useful for neurological diseases of the peripheral and central nervous systems of animals.

Abstract: Amine represented by the following formula (1), or their acid addition salts or their quaternary ammonium salts. ##STR1## The amines of formula (1) or their pharmaceutically acceptable acid addition salts or quaternary ammonium salts are useful for the treatment and prevention of heart diseases of animals, particularly arrhythima, myocardial infarction, angina pectoris and heart failure and psychoneurological diseases.

Abstract: Disclosed is a novel .alpha.-chloroketone derivative as a synthesis intermediate of N-cyano-N'-methyl-N"-(2-((5-methyl-1H-imidazol-4-yl)methylthio)ethyl)guani dine (general name: Cimetidine) which shows an action of controlling the secretion of gastric acid and is valuable as a medicine for remedy of a gastric ulcer. This .alpha.-chloroketone derivative is prepared by reacting disulfide derivative with sulfuryl chloride and reacting the reaction product with methylvinyl ketone or by reacting a mercapto derivative with 3-chloro-3-buten-2-one.

Abstract: Discloses indan derivatives represented by the general formula [1] ##STR1## wherein R is a lower alkoxy group, a phenoxy group, ##STR2## whereupon R.sup.1 and R.sup.2 are, respectively, a hydrogen atom, a lower alkyl, lower alkenyl, phenyl, or phenyl group substituted by halogen atoms, or a monopholino group.The indan derivatives demonstrated satisfactory results in respect of a weeding effect and safety in practical use.

Abstract: A pharmaceutical composition comprising a pyrimidine represented by the following formula ##STR1## wherein R.sup.1 represents a hydrogen atom, an acyl group having 2 to 4 carbon atoms, an alkoxycarbonyl group having 2 to 5 carbon atoms, an alkoxycarbonylmethyl group having 3 to 5 carbon atoms, a 3,4-dimethoxybenzoyl group or a 3,4-methylenedioxybenzyl group,R.sup.2 represents a hydrogen atom, an amino group, a monoalkylamino group having 1 to 4 carbon atoms, an alkoxy group having 1 to 5 carbon atoms or an alkoxycarbonyl group having 2 to 4 carbon atoms,R.sup.3 represents a hydrogen atom, an alkoxycarbonyl group having 2 to 4 carbon atoms, a dialkylaminocarbonyl group having 1 to 9 carbon atoms in each alkyl moiety, an alkoxy group having 1 to 5 carbon atoms, or a hydroxyethyl group, R.sup.2 and R.sup.3, together with the carbon atoms to which they are bonded, may form a 5- to 7-membered carbocyclic ring or a heterocyclic ring having N, O or S as the hetero atom, and R.sup.

Abstract: A method of producing polysilane compounds which comprises: polymerizing a monomeric silane compound represented by the general formula of ##STR1## wherein R independently represents hydrogen or hydrocarbon group, but not both R's are hydrogen at the same time, in the presence of an organometallic complex of Ni, Co, Ru, Pd or Ir.

Abstract: The present invention provides a cyanoguanidine derivative which is a precursor for the synthesis of N-cyano-N'-methyl-N"-[2-{(5-methyl-1H-imidazol-4-yl)methylthio}ethyl]-guan idine (Cimetidine) or its related compound, which has an action of controlling secretion of acid in the stomach based on the histamine H.sub.2 receptor antagonism and is valuable as a drug for treating gastric ulcer. This cyanoguanidine derivative is prepared by reacting other cyanoguanidine derivative with a halogenating agent.

Abstract: The present invention relates to novel 2-piperazinopyrimidine derivatives represented by the following general formula [I] which are useful as, for example, an active ingredient of herbicides ##STR1## wherein R.sup.1 is a hydrogen atom or an aralkyl group and Y is one of the groups represented by the following general formulas [II] to [VII] ##STR2## (wherein a and b are positions to be bound to positions 4 and 5 of the pyrimidine ring of the formula [I], respectively; l.sub.1 and l.sub.2 each are an integer of 2 to 4; l.sub.3 is 2 or 0; l.sub.4 is 0 or 1, provided that l.sub.4 is 0 when l.sub.3 is 2 and l.sub.4 is 1 when l.sub.3 is 0; l.sub.5 is 2 or 3; l.sub.6 is 1 or 2; l.sub.7 is 2 or 3; R.sup.2 is a hydroxyl group or a toluenesulfonyloxy group; and R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 each are a hydrogen atom or a lower alkyl group).

Abstract: Disclosed herein is an antihypertensive preparation containing, as an active component, a novel quinazoline derivative represented by the following general formula or a salt thereof: ##STR1## wherein R.sup.100 means a hydrogen atom or methoxy group, R.sup.200 and R.sup.300 denote individually a hydrogen atom or lower alkoxy group, R.sup.400 is a hydrogen atom or amino group, l stands for 2 or 3, and Het is a specific hetero ring group.