Patents by Inventor Keiji Kubo

Keiji Kubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11866528
    Abstract: A polymer comprising a structural unit derived from a compound (A) represented by formula (I): wherein X, Y, R1, R2, R7, R8, R3, R4, R5, R6, J, and n are as defined in the description, provides a resin composition that has an excellent curability and sufficiently polymerizes for curing even in the presence of oxygen in an air atmosphere to form a cured product having excellent appearance.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: January 9, 2024
    Assignee: KURARAY CO., LTD.
    Inventors: Daiki Noguchi, Takashi Fukumoto, Keiji Kubo
  • Patent number: 11845818
    Abstract: The present invention provides a polymer which has a polymerizable functional group but still can be thermoformed without being crosslinked and which undergoes crosslinking upon irradiation with an active energy ray after being formed, and a composition including the polymer. An active energy ray crosslinkable thermoplastic polymer includes specific monomer units (1). The ratio of the number of moles of the monomer units represented by the general formula (1) to the number of moles of all monomer units constituting the polymer is not less than 1 mol %. The number average molecular weight (Mn) of the active energy ray crosslinkable thermoplastic polymer is 20,000 to 500,000.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: December 19, 2023
    Assignee: KURARAY CO., LTD.
    Inventors: Kenta Takemoto, Keiji Kubo
  • Patent number: 11760816
    Abstract: Provided is an unsaturated double bond-containing compound capable of sufficiently advancing a crosslinking reaction or a curing reaction when used for a coating material or the like and having oxygen absorption performance. The present invention also provides an oxygen absorbent containing the unsaturated double bond-containing compound and a resin composition containing the same. Provided are an unsaturated double bond-containing compound represented by general formula (I), an oxygen absorbent containing the same, and a resin composition.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: September 19, 2023
    Assignee: KURARAY CO., LTD.
    Inventors: Daiki Noguchi, Takashi Fukumoto, Katsuji Ujita, Keiji Kubo
  • Publication number: 20220251249
    Abstract: The present invention provides a polymer which has a polymerizable functional group but still can be thermoformed without being crosslinked and which undergoes crosslinking upon irradiation with an active energy ray after being formed, and a composition including the polymer. An active energy ray crosslinkable thermoplastic polymer includes specific monomer units (1). The ratio of the number of moles of the monomer units represented by the general formula (1) to the number of moles of all monomer units constituting the polymer is not less than 1 mol %. The number average molecular weight (Mn) of the active energy ray crosslinkable thermoplastic polymer is 20,000 to 500,000.
    Type: Application
    Filed: March 12, 2020
    Publication date: August 11, 2022
    Applicant: KURARAY CO., LTD.
    Inventors: Kenta TAKEMOTO, Keiji KUBO
  • Publication number: 20220195385
    Abstract: [Problem to be Solved] Provided is a motile cell sorting device that can effectively sort motile cells, such as sperms, having excellent motility and morphology by performing image analysis when animal cells are sorted. [Means for Solution] The motile cell sorting device 1 comprises a storage unit 3, a first introduction unit (cell injection channel) 5, a first introduction control unit 7, a first holding unit (cell capture area) 9, a first derivation unit (cell collection channel) 11, a first derivation control unit 13, a collection unit (liquid storage) 15, a photographing unit 17, and a first controller 19.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 23, 2022
    Applicants: The University of Tokyo, St. Marianna University School of Medicine, International University of Health and Welfare, Japanese Organization for Medical Device Development, Inc.
    Inventors: Kazuhiro KAWAMURA, Masashi IKEUCHI, Keiji KUBO
  • Publication number: 20210246244
    Abstract: A composition comprising a compound (A) represented by formula (I): wherein R1 and R2 each independently represent any one selected from the group consisting of a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, an alkenyl group having 2 to 6 carbon atoms, an aryl group, and an aralkyl group; R3 represents any one selected from the group consisting of a (meth)acryloyl group, a 4-vinylphenyl group, and an alkenyl group having 2 to 6 carbon atoms; and n represents an integer of 0 to 5, and a polyfunctional compound (B) other than the compound (A) is excellent in the curability because the composition sufficiently polymerizes even in the presence of oxygen, for example, in an air atmosphere.
    Type: Application
    Filed: April 17, 2019
    Publication date: August 12, 2021
    Applicant: KURARAY CO., LTD.
    Inventors: Daiki NOGUCHI, Takashi FUKUMOTO, Keiji KUBO
  • Publication number: 20210246238
    Abstract: A polymer comprising a structural unit derived from a compound (A) represented by formula (I): wherein X, Y, R1, R2, R7, R8, R3, R4, R5, R6, J, and n are as defined in the description, provides a resin composition that has an excellent curability and sufficiently polymerizes for curing even in the presence of oxygen in an air atmosphere to form a cured product having excellent appearance.
    Type: Application
    Filed: April 12, 2019
    Publication date: August 12, 2021
    Applicant: KURARAY CO., LTD.
    Inventors: Daiki NOGUCHI, Takashi FUKUMOTO, Keiji KUBO
  • Publication number: 20210024665
    Abstract: Provided is an unsaturated double bond-containing compound capable of sufficiently advancing a crosslinking reaction or a curing reaction when used for a coating material or the like and having oxygen absorption performance. The present invention also provides an oxygen absorbent containing the unsaturated double bond-containing compound and a resin composition containing the same. Provided are an unsaturated double bond-containing compound represented by general formula (I), an oxygen absorbent containing the same, and a resin composition.
    Type: Application
    Filed: November 21, 2018
    Publication date: January 28, 2021
    Applicant: Kuraray Co., Ltd.
    Inventors: Daiki NOGUCHI, Takashi FUKUMOTO, Katsuji UJITA, Keiji KUBO
  • Patent number: 8993192
    Abstract: An electrolyte membrane having a structure wherein fine rubber particles having substantially no ion-conducting group and having an average particle size of 20 nm to 1 ?m are uniformly dispersed in a matrix including a resin component having ion-conducting group. The electrolyte membrane has high bonding ability to electrodes and does not cause cracks and ruptures because it is kept flexible even under low humid or absolutely dried condition, in addition, shows high ion conductivity even under low humid or absolutely dried condition because the matrix having ion-conducting groups are continuous.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: March 31, 2015
    Assignee: Kuraray Co., Ltd.
    Inventors: Tomohiro Ono, Takeshi Nakano, Taketomo Yamashita, Keiji Kubo, Nozomu Sugoh
  • Patent number: 8697865
    Abstract: The present invention provides a cyclic amide derivative useful as a drug for treating thrombosis, which is represented by the formula (I): wherein R1 represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents a bond or an optionally substituted divalent chain hydrocarbon group, a represents 0, 1, or 2, X1 represents an optionally substituted lower alkylene or an optionally substituted lower alkenylene, Y1 represents —C(O)—, —S(O)— or —S(O)2—, A represents a piperazine ring which may be further substituted or a piperidine ring which may be further substituted, X2 represents a bond or an optionally substituted lower alkylene, Y2 represents —C(O)—, —S(O)—, —S(O)2— or —C(?NR7)—, X3 represents an optionally substituted C1-4 alkylene or an optionally substituted C2-4 alkenylene, Z3 represents —N(R4)—, —O— or a bond, Z1 represents —C(R2) (R2?)—, —N(R2)—, etc., and Z2 represents —C(R3)(R3?)—, —N(R3)—, etc., or a salt thereof.
    Type: Grant
    Filed: March 2, 2010
    Date of Patent: April 15, 2014
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Keiji Kubo, Yasuhiro Imaeda
  • Patent number: 8420276
    Abstract: In a membrane-electrode assembly for polymer electrolyte fuel cells comprising a polymer electrolyte membrane and two gas diffusion electrodes being bonded to the membrane so that the membrane can be between them, at least one catalyst layer constituting the gas diffusion electrodes characterized in that the ion-conductive binder comprises a block copolymer having a particle size of 1 ?m or less comprising a polymer block (A) having ion-conductive groups and a polymer block (B) having no ion-conductive group, both polymer blocks phase separate from each other, polymer block (A) forms a continuous phase, and the contact parts of the block copolymer with catalyst particles are comprised of polymer block (A) having ion-conductive groups; a membrane-electrode assembly and a polymer electrolyte fuel cell.
    Type: Grant
    Filed: January 23, 2008
    Date of Patent: April 16, 2013
    Assignee: Kuraray Co., Ltd.
    Inventors: Shinji Nakai, Keiji Kubo, Hiroyuki Ohgi, Tomohiro Ono
  • Patent number: 8263286
    Abstract: A membrane-electrode assembly for polymer electrolyte fuel cells comprising a polymer electrolyte membrane and two gas diffusion electrodes being bonded to the membrane so that the membrane can be between them, in which assembly each gas diffusion electrode is comprised of an electrode catalyst layer and a gas diffusion layer, intermediate layer(s) being an ion conductor is/are arranged between the electrode catalyst layer(s) and the membrane, the ion conductor mainly comprises a block copolymer comprising a polymer block (A) having ion-conductive groups and a polymer block (B) having no ion-conductive group, both blocks phase-separate from each other, (A) forms a continuous phase, and the contact part(s) of the intermediate layer(s) with the polymer electrolyte membrane and the contact part(s) of the intermediate layer(s) with the electrode catalyst layer(s) are comprised of polymer block (A) having ion-conductive groups; and a polymer electrolyte fuel cell wherein the assembly is used.
    Type: Grant
    Filed: January 28, 2009
    Date of Patent: September 11, 2012
    Assignee: Kuraray Co., Ltd.
    Inventors: Shinji Nakai, Keiji Kubo, Tomohiro Ono, Hiroyuki Ohgi
  • Publication number: 20110300469
    Abstract: An electrolyte membrane having a structure wherein fine rubber particles having substantially no ion-conducting group and having an average particle size of 20 nm to 1 ?m are uniformly dispersed in a matrix including a resin component having ion-conducting group. The electrolyte membrane has high bonding ability to electrodes and does not cause cracks and ruptures because it is kept flexible even under low humid or absolutely dried condition, in addition, shows high ion conductivity even under low humid or absolutely dried condition because the matrix having ion-conducting groups are continuous.
    Type: Application
    Filed: February 12, 2010
    Publication date: December 8, 2011
    Applicant: Kuraray Co., Ltd.
    Inventors: Tomohiro Ono, Takeshi Nakano, Taketomo Yamashita, Keiji Kubo, Nozomu Sugoh
  • Publication number: 20110009389
    Abstract: There is provided an imidazole derivative useful as a thrombosis treating agent, which is represented by the formula (I): wherein R represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents a bond or an optionally substituted divalent linear hydrocarbon group, X represents an optionally substituted divalent hydrocarbon group, Y represents —CO—, —S(O)—, —S(O)2— or a bond, ring A represents an optionally substituted pyrrolidine ring, an optionally substituted piperidine ring or an optionally substituted perhydroazepine ring, Z1 and Z3 independently represent a bond or an optionally substituted divalent linear hydrocarbon group, Z2 represents —N(R1)—, —O—, —S(O)—, —S(O)2—, —CO—, —CH(R1)— or a bond, ring B represents an optionally substituted imidazole ring, wherein a substituent which the optionally substituted imidazole ring represented by ring B may have may be taken together with R1 to form an optionally substituted ring, and a represents 0
    Type: Application
    Filed: September 10, 2010
    Publication date: January 13, 2011
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Keiji KUBO, Takanobu KUROITA, Yasuhiro IMAEDA, Masaki KAWAMURA
  • Publication number: 20100323269
    Abstract: In a membrane-electrode assembly for polymer electrolyte fuel cells comprising a polymer electrolyte membrane and two gas diffusion electrodes being bonded to the membrane so that the membrane can be between them, at least one catalyst layer constituting the gas diffusion electrodes characterized in that the ion-conductive binder comprises a block copolymer having a particle size of 1 ?m or less comprising a polymer block (A) having ion-conductive groups and a polymer block (B) having no ion-conductive group, both polymer blocks phase separate from each other, polymer block (A) forms a continuous phase, and the contact parts of the block copolymer with catalyst particles are comprised of polymer block (A) having ion-conductive groups; a membrane-electrode assembly and a polymer electrolyte fuel cell.
    Type: Application
    Filed: January 23, 2008
    Publication date: December 23, 2010
    Applicant: Kuraray Co., Ltd.
    Inventors: Shinji Nakai, Keiji Kubo, Hiroyuki Ohgi, Tomohiro Ono
  • Publication number: 20100310965
    Abstract: A membrane-electrode assembly for polymer electrolyte fuel cells comprising a polymer electrolyte membrane and two gas diffusion electrodes being bonded to the membrane so that the membrane can be between them, in which assembly each gas diffusion electrode is comprised of an electrode catalyst layer and a gas diffusion layer, intermediate layer(s) being an ion conductor is/are arranged between the electrode catalyst layer(s) and the membrane, the ion conductor mainly comprises a block copolymer comprising a polymer block (A) having ion-conductive groups and a polymer block (B) having no ion-conductive group, both blocks phase-separate from each other, (A) forms a continuous phase, and the contact part(s) of the intermediate layer(s) with the polymer electrolyte membrane and the contact part(s) of the intermediate layer(s) with the electrode catalyst layer(s) are comprised of polymer block (A) having ion-conductive groups; and a polymer electrolyte fuel cell wherein the assembly is used.
    Type: Application
    Filed: January 28, 2009
    Publication date: December 9, 2010
    Applicant: Kuraray Co., Ltd.
    Inventors: Shinji Nakai, Keiji Kubo, Tomohiro Ono, Hiroyuki Ohgi
  • Patent number: 7820673
    Abstract: The present invention provides a urea derivative or a salt thereof, which is useful as a therapeutic agent for thrombosis.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: October 26, 2010
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Keiji Kubo, Yasuhiro Imaeda
  • Patent number: 7803822
    Abstract: The present invention relates to a thrombin receptor antagonist containing a compound represented by the formula (I) wherein R1a, R1b and R2 are each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, or an optionally substituted alkoxy, R3 is a group represented by the formula —NHCOR4, —NHSO2R5, —NHCON(R6a)(R6b), —NHCOOR7 or —CONHR8 wherein R4, R5, R6a, R6b, R7 and R8 are each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group and the like), ring A is monocyclic aromatic ring optionally further having substituent(s), R1a and R1b are optionally bonded to each other to form an optionally substituted nitrogen-containing non-aromatic heterocycle, or a salt thereof or a prodrug thereof.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: September 28, 2010
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Keiji Kubo, Mamoru Tobisu, Eiji Honda, Takahiko Taniguchi, Yoshiyuki Fukase, Masaki Kawamura, Masaharu Nakayama
  • Patent number: 7745623
    Abstract: The present invention provides a cyclic amide derivative useful as a drug for treating thrombosis, which is represented by the formula (I): wherein R1 represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents a bond or an optionally substituted divalent chain hydrocarbon group, a represents 0, 1, or 2, X1 represents an optionally substituted lower alkylene or an optionally substituted lower alkenylene, Y1 represents —C(O)—, —S(O)— or —S(O)2—, A represents a piperazine ring which may be further substituted or a piperidine ring which may be further substituted, X2 represents a bond or an optionally substituted lower alkylene, Y2 represents —C(O)—, —S(O)—, —S(O)2— or —C(?NR7)—, X3 represents an optionally substituted C1-4 alkylene or an optionally substituted C2-4 alkenylene, Z3 represents —N(R4)—, —O— or a bond, Z1 represents —C(R2)(R2?)—, —N(R2)—, etc., and Z2 represents —C(R3)(R3?)—, —N(R3)—, etc., or a salt thereof.
    Type: Grant
    Filed: May 20, 2005
    Date of Patent: June 29, 2010
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Keiji Kubo, Yasuhiro Imaeda
  • Publication number: 20100160629
    Abstract: The present invention provides a cyclic amide derivative useful as a drug for treating thrombosis, which is represented by the formula (I): wherein R1 represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents a bond or an optionally substituted divalent chain hydrocarbon group, a represents 0, 1, or 2, X1 represents an optionally substituted lower alkylene or an optionally substituted lower alkenylene, Y1 represents —C(O)—, —S(O)— or —S(O)2—, A represents a piperazine ring which may be further substituted or a piperidine ring which may be further substituted, X2 represents a bond or an optionally substituted lower alkylene, Y2 represents —C(O)—, —S(O)—, —S(O)2— or —C(?NR7)—, X3 represents an optionally substituted C1-4 alkylene or an optionally substituted C2-4 alkenylene, Z3 represents —N(R4)—, —O— or a bond, Z1 represents —C(R2)(R2?)—, —N(R2)—, etc., and Z2 represents —C(R3)(R3?)—, —N(R3)—, etc., or a salt thereof.
    Type: Application
    Filed: March 2, 2010
    Publication date: June 24, 2010
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Keiji KUBO, Yasuhiro Imaeda