Patents by Inventor Keiji Kubo
Keiji Kubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11866528Abstract: A polymer comprising a structural unit derived from a compound (A) represented by formula (I): wherein X, Y, R1, R2, R7, R8, R3, R4, R5, R6, J, and n are as defined in the description, provides a resin composition that has an excellent curability and sufficiently polymerizes for curing even in the presence of oxygen in an air atmosphere to form a cured product having excellent appearance.Type: GrantFiled: April 12, 2019Date of Patent: January 9, 2024Assignee: KURARAY CO., LTD.Inventors: Daiki Noguchi, Takashi Fukumoto, Keiji Kubo
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Patent number: 11845818Abstract: The present invention provides a polymer which has a polymerizable functional group but still can be thermoformed without being crosslinked and which undergoes crosslinking upon irradiation with an active energy ray after being formed, and a composition including the polymer. An active energy ray crosslinkable thermoplastic polymer includes specific monomer units (1). The ratio of the number of moles of the monomer units represented by the general formula (1) to the number of moles of all monomer units constituting the polymer is not less than 1 mol %. The number average molecular weight (Mn) of the active energy ray crosslinkable thermoplastic polymer is 20,000 to 500,000.Type: GrantFiled: March 12, 2020Date of Patent: December 19, 2023Assignee: KURARAY CO., LTD.Inventors: Kenta Takemoto, Keiji Kubo
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Patent number: 11760816Abstract: Provided is an unsaturated double bond-containing compound capable of sufficiently advancing a crosslinking reaction or a curing reaction when used for a coating material or the like and having oxygen absorption performance. The present invention also provides an oxygen absorbent containing the unsaturated double bond-containing compound and a resin composition containing the same. Provided are an unsaturated double bond-containing compound represented by general formula (I), an oxygen absorbent containing the same, and a resin composition.Type: GrantFiled: November 21, 2018Date of Patent: September 19, 2023Assignee: KURARAY CO., LTD.Inventors: Daiki Noguchi, Takashi Fukumoto, Katsuji Ujita, Keiji Kubo
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Publication number: 20220251249Abstract: The present invention provides a polymer which has a polymerizable functional group but still can be thermoformed without being crosslinked and which undergoes crosslinking upon irradiation with an active energy ray after being formed, and a composition including the polymer. An active energy ray crosslinkable thermoplastic polymer includes specific monomer units (1). The ratio of the number of moles of the monomer units represented by the general formula (1) to the number of moles of all monomer units constituting the polymer is not less than 1 mol %. The number average molecular weight (Mn) of the active energy ray crosslinkable thermoplastic polymer is 20,000 to 500,000.Type: ApplicationFiled: March 12, 2020Publication date: August 11, 2022Applicant: KURARAY CO., LTD.Inventors: Kenta TAKEMOTO, Keiji KUBO
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Publication number: 20220195385Abstract: [Problem to be Solved] Provided is a motile cell sorting device that can effectively sort motile cells, such as sperms, having excellent motility and morphology by performing image analysis when animal cells are sorted. [Means for Solution] The motile cell sorting device 1 comprises a storage unit 3, a first introduction unit (cell injection channel) 5, a first introduction control unit 7, a first holding unit (cell capture area) 9, a first derivation unit (cell collection channel) 11, a first derivation control unit 13, a collection unit (liquid storage) 15, a photographing unit 17, and a first controller 19.Type: ApplicationFiled: March 27, 2020Publication date: June 23, 2022Applicants: The University of Tokyo, St. Marianna University School of Medicine, International University of Health and Welfare, Japanese Organization for Medical Device Development, Inc.Inventors: Kazuhiro KAWAMURA, Masashi IKEUCHI, Keiji KUBO
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Publication number: 20210246244Abstract: A composition comprising a compound (A) represented by formula (I): wherein R1 and R2 each independently represent any one selected from the group consisting of a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, an alkenyl group having 2 to 6 carbon atoms, an aryl group, and an aralkyl group; R3 represents any one selected from the group consisting of a (meth)acryloyl group, a 4-vinylphenyl group, and an alkenyl group having 2 to 6 carbon atoms; and n represents an integer of 0 to 5, and a polyfunctional compound (B) other than the compound (A) is excellent in the curability because the composition sufficiently polymerizes even in the presence of oxygen, for example, in an air atmosphere.Type: ApplicationFiled: April 17, 2019Publication date: August 12, 2021Applicant: KURARAY CO., LTD.Inventors: Daiki NOGUCHI, Takashi FUKUMOTO, Keiji KUBO
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Publication number: 20210246238Abstract: A polymer comprising a structural unit derived from a compound (A) represented by formula (I): wherein X, Y, R1, R2, R7, R8, R3, R4, R5, R6, J, and n are as defined in the description, provides a resin composition that has an excellent curability and sufficiently polymerizes for curing even in the presence of oxygen in an air atmosphere to form a cured product having excellent appearance.Type: ApplicationFiled: April 12, 2019Publication date: August 12, 2021Applicant: KURARAY CO., LTD.Inventors: Daiki NOGUCHI, Takashi FUKUMOTO, Keiji KUBO
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Publication number: 20210024665Abstract: Provided is an unsaturated double bond-containing compound capable of sufficiently advancing a crosslinking reaction or a curing reaction when used for a coating material or the like and having oxygen absorption performance. The present invention also provides an oxygen absorbent containing the unsaturated double bond-containing compound and a resin composition containing the same. Provided are an unsaturated double bond-containing compound represented by general formula (I), an oxygen absorbent containing the same, and a resin composition.Type: ApplicationFiled: November 21, 2018Publication date: January 28, 2021Applicant: Kuraray Co., Ltd.Inventors: Daiki NOGUCHI, Takashi FUKUMOTO, Katsuji UJITA, Keiji KUBO
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Patent number: 8993192Abstract: An electrolyte membrane having a structure wherein fine rubber particles having substantially no ion-conducting group and having an average particle size of 20 nm to 1 ?m are uniformly dispersed in a matrix including a resin component having ion-conducting group. The electrolyte membrane has high bonding ability to electrodes and does not cause cracks and ruptures because it is kept flexible even under low humid or absolutely dried condition, in addition, shows high ion conductivity even under low humid or absolutely dried condition because the matrix having ion-conducting groups are continuous.Type: GrantFiled: February 12, 2010Date of Patent: March 31, 2015Assignee: Kuraray Co., Ltd.Inventors: Tomohiro Ono, Takeshi Nakano, Taketomo Yamashita, Keiji Kubo, Nozomu Sugoh
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Patent number: 8697865Abstract: The present invention provides a cyclic amide derivative useful as a drug for treating thrombosis, which is represented by the formula (I): wherein R1 represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents a bond or an optionally substituted divalent chain hydrocarbon group, a represents 0, 1, or 2, X1 represents an optionally substituted lower alkylene or an optionally substituted lower alkenylene, Y1 represents —C(O)—, —S(O)— or —S(O)2—, A represents a piperazine ring which may be further substituted or a piperidine ring which may be further substituted, X2 represents a bond or an optionally substituted lower alkylene, Y2 represents —C(O)—, —S(O)—, —S(O)2— or —C(?NR7)—, X3 represents an optionally substituted C1-4 alkylene or an optionally substituted C2-4 alkenylene, Z3 represents —N(R4)—, —O— or a bond, Z1 represents —C(R2) (R2?)—, —N(R2)—, etc., and Z2 represents —C(R3)(R3?)—, —N(R3)—, etc., or a salt thereof.Type: GrantFiled: March 2, 2010Date of Patent: April 15, 2014Assignee: Takeda Pharmaceutical Company LimitedInventors: Keiji Kubo, Yasuhiro Imaeda
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Patent number: 8420276Abstract: In a membrane-electrode assembly for polymer electrolyte fuel cells comprising a polymer electrolyte membrane and two gas diffusion electrodes being bonded to the membrane so that the membrane can be between them, at least one catalyst layer constituting the gas diffusion electrodes characterized in that the ion-conductive binder comprises a block copolymer having a particle size of 1 ?m or less comprising a polymer block (A) having ion-conductive groups and a polymer block (B) having no ion-conductive group, both polymer blocks phase separate from each other, polymer block (A) forms a continuous phase, and the contact parts of the block copolymer with catalyst particles are comprised of polymer block (A) having ion-conductive groups; a membrane-electrode assembly and a polymer electrolyte fuel cell.Type: GrantFiled: January 23, 2008Date of Patent: April 16, 2013Assignee: Kuraray Co., Ltd.Inventors: Shinji Nakai, Keiji Kubo, Hiroyuki Ohgi, Tomohiro Ono
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Patent number: 8263286Abstract: A membrane-electrode assembly for polymer electrolyte fuel cells comprising a polymer electrolyte membrane and two gas diffusion electrodes being bonded to the membrane so that the membrane can be between them, in which assembly each gas diffusion electrode is comprised of an electrode catalyst layer and a gas diffusion layer, intermediate layer(s) being an ion conductor is/are arranged between the electrode catalyst layer(s) and the membrane, the ion conductor mainly comprises a block copolymer comprising a polymer block (A) having ion-conductive groups and a polymer block (B) having no ion-conductive group, both blocks phase-separate from each other, (A) forms a continuous phase, and the contact part(s) of the intermediate layer(s) with the polymer electrolyte membrane and the contact part(s) of the intermediate layer(s) with the electrode catalyst layer(s) are comprised of polymer block (A) having ion-conductive groups; and a polymer electrolyte fuel cell wherein the assembly is used.Type: GrantFiled: January 28, 2009Date of Patent: September 11, 2012Assignee: Kuraray Co., Ltd.Inventors: Shinji Nakai, Keiji Kubo, Tomohiro Ono, Hiroyuki Ohgi
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Publication number: 20110300469Abstract: An electrolyte membrane having a structure wherein fine rubber particles having substantially no ion-conducting group and having an average particle size of 20 nm to 1 ?m are uniformly dispersed in a matrix including a resin component having ion-conducting group. The electrolyte membrane has high bonding ability to electrodes and does not cause cracks and ruptures because it is kept flexible even under low humid or absolutely dried condition, in addition, shows high ion conductivity even under low humid or absolutely dried condition because the matrix having ion-conducting groups are continuous.Type: ApplicationFiled: February 12, 2010Publication date: December 8, 2011Applicant: Kuraray Co., Ltd.Inventors: Tomohiro Ono, Takeshi Nakano, Taketomo Yamashita, Keiji Kubo, Nozomu Sugoh
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Publication number: 20110009389Abstract: There is provided an imidazole derivative useful as a thrombosis treating agent, which is represented by the formula (I): wherein R represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents a bond or an optionally substituted divalent linear hydrocarbon group, X represents an optionally substituted divalent hydrocarbon group, Y represents —CO—, —S(O)—, —S(O)2— or a bond, ring A represents an optionally substituted pyrrolidine ring, an optionally substituted piperidine ring or an optionally substituted perhydroazepine ring, Z1 and Z3 independently represent a bond or an optionally substituted divalent linear hydrocarbon group, Z2 represents —N(R1)—, —O—, —S(O)—, —S(O)2—, —CO—, —CH(R1)— or a bond, ring B represents an optionally substituted imidazole ring, wherein a substituent which the optionally substituted imidazole ring represented by ring B may have may be taken together with R1 to form an optionally substituted ring, and a represents 0Type: ApplicationFiled: September 10, 2010Publication date: January 13, 2011Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Keiji KUBO, Takanobu KUROITA, Yasuhiro IMAEDA, Masaki KAWAMURA
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Publication number: 20100323269Abstract: In a membrane-electrode assembly for polymer electrolyte fuel cells comprising a polymer electrolyte membrane and two gas diffusion electrodes being bonded to the membrane so that the membrane can be between them, at least one catalyst layer constituting the gas diffusion electrodes characterized in that the ion-conductive binder comprises a block copolymer having a particle size of 1 ?m or less comprising a polymer block (A) having ion-conductive groups and a polymer block (B) having no ion-conductive group, both polymer blocks phase separate from each other, polymer block (A) forms a continuous phase, and the contact parts of the block copolymer with catalyst particles are comprised of polymer block (A) having ion-conductive groups; a membrane-electrode assembly and a polymer electrolyte fuel cell.Type: ApplicationFiled: January 23, 2008Publication date: December 23, 2010Applicant: Kuraray Co., Ltd.Inventors: Shinji Nakai, Keiji Kubo, Hiroyuki Ohgi, Tomohiro Ono
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Publication number: 20100310965Abstract: A membrane-electrode assembly for polymer electrolyte fuel cells comprising a polymer electrolyte membrane and two gas diffusion electrodes being bonded to the membrane so that the membrane can be between them, in which assembly each gas diffusion electrode is comprised of an electrode catalyst layer and a gas diffusion layer, intermediate layer(s) being an ion conductor is/are arranged between the electrode catalyst layer(s) and the membrane, the ion conductor mainly comprises a block copolymer comprising a polymer block (A) having ion-conductive groups and a polymer block (B) having no ion-conductive group, both blocks phase-separate from each other, (A) forms a continuous phase, and the contact part(s) of the intermediate layer(s) with the polymer electrolyte membrane and the contact part(s) of the intermediate layer(s) with the electrode catalyst layer(s) are comprised of polymer block (A) having ion-conductive groups; and a polymer electrolyte fuel cell wherein the assembly is used.Type: ApplicationFiled: January 28, 2009Publication date: December 9, 2010Applicant: Kuraray Co., Ltd.Inventors: Shinji Nakai, Keiji Kubo, Tomohiro Ono, Hiroyuki Ohgi
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Patent number: 7820673Abstract: The present invention provides a urea derivative or a salt thereof, which is useful as a therapeutic agent for thrombosis.Type: GrantFiled: December 15, 2004Date of Patent: October 26, 2010Assignee: Takeda Pharmaceutical Company LimitedInventors: Keiji Kubo, Yasuhiro Imaeda
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Patent number: 7803822Abstract: The present invention relates to a thrombin receptor antagonist containing a compound represented by the formula (I) wherein R1a, R1b and R2 are each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, or an optionally substituted alkoxy, R3 is a group represented by the formula —NHCOR4, —NHSO2R5, —NHCON(R6a)(R6b), —NHCOOR7 or —CONHR8 wherein R4, R5, R6a, R6b, R7 and R8 are each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group and the like), ring A is monocyclic aromatic ring optionally further having substituent(s), R1a and R1b are optionally bonded to each other to form an optionally substituted nitrogen-containing non-aromatic heterocycle, or a salt thereof or a prodrug thereof.Type: GrantFiled: April 6, 2006Date of Patent: September 28, 2010Assignee: Takeda Pharmaceutical Company LimitedInventors: Keiji Kubo, Mamoru Tobisu, Eiji Honda, Takahiko Taniguchi, Yoshiyuki Fukase, Masaki Kawamura, Masaharu Nakayama
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Patent number: 7745623Abstract: The present invention provides a cyclic amide derivative useful as a drug for treating thrombosis, which is represented by the formula (I): wherein R1 represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents a bond or an optionally substituted divalent chain hydrocarbon group, a represents 0, 1, or 2, X1 represents an optionally substituted lower alkylene or an optionally substituted lower alkenylene, Y1 represents —C(O)—, —S(O)— or —S(O)2—, A represents a piperazine ring which may be further substituted or a piperidine ring which may be further substituted, X2 represents a bond or an optionally substituted lower alkylene, Y2 represents —C(O)—, —S(O)—, —S(O)2— or —C(?NR7)—, X3 represents an optionally substituted C1-4 alkylene or an optionally substituted C2-4 alkenylene, Z3 represents —N(R4)—, —O— or a bond, Z1 represents —C(R2)(R2?)—, —N(R2)—, etc., and Z2 represents —C(R3)(R3?)—, —N(R3)—, etc., or a salt thereof.Type: GrantFiled: May 20, 2005Date of Patent: June 29, 2010Assignee: Takeda Pharmaceutical Company LimitedInventors: Keiji Kubo, Yasuhiro Imaeda
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Publication number: 20100160629Abstract: The present invention provides a cyclic amide derivative useful as a drug for treating thrombosis, which is represented by the formula (I): wherein R1 represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents a bond or an optionally substituted divalent chain hydrocarbon group, a represents 0, 1, or 2, X1 represents an optionally substituted lower alkylene or an optionally substituted lower alkenylene, Y1 represents —C(O)—, —S(O)— or —S(O)2—, A represents a piperazine ring which may be further substituted or a piperidine ring which may be further substituted, X2 represents a bond or an optionally substituted lower alkylene, Y2 represents —C(O)—, —S(O)—, —S(O)2— or —C(?NR7)—, X3 represents an optionally substituted C1-4 alkylene or an optionally substituted C2-4 alkenylene, Z3 represents —N(R4)—, —O— or a bond, Z1 represents —C(R2)(R2?)—, —N(R2)—, etc., and Z2 represents —C(R3)(R3?)—, —N(R3)—, etc., or a salt thereof.Type: ApplicationFiled: March 2, 2010Publication date: June 24, 2010Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Keiji KUBO, Yasuhiro Imaeda