Patents by Inventor Keiji Tamura

Keiji Tamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220176341
    Abstract: Provided is a metal oxide containing a brownmillerite-type manganese oxide represented by (Ca2-xAx)(MnyAlzE2-y-z)wO5+? (in the formula, A represents one or more alkaline earth metal elements other than Ca; E represents one or more 3d transition metal elements or earth metal elements other than Mn and Al; and x, y, z, ?, and w satisfy 0?x?2, 0<y?2, 0?z<2, 0<y+z?2, 0???0.5, and 0.8?w?1.2), wherein the metal oxide has a defect in a (020) plane of a crystal of the brownmillerite-type manganese oxide.
    Type: Application
    Filed: February 25, 2022
    Publication date: June 9, 2022
    Applicants: Mitsubishi Chemical Corporation, KANAGAWA UNIVERSITY
    Inventors: Ryo NISHIDA, Keiji YAMAHARA, Teruki MOTOHASHI, Miwa SAITO, Sayaka TAMURA, Tomohiro ISEKI
  • Publication number: 20210315892
    Abstract: A therapeutic agent for treating at least one disease selected from the group consisting of inflammatory diseases, autoimmune diseases, fibrotic diseases, and cancer diseases, comprising: at least one selected from the group consisting of a compound represented by the following general formula (1) and pharmacologically acceptable salts thereof as an active ingredient. [In the formula (1), R1 and R2 may be the same or different and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a carboxy group, a cyano group, an optionally substituted C1-6 alkyl group et al.; R3 represents a hydrogen atom; R4 represents an optionally substituted 4- to 10-membered monocyclic heterocyclic group containing 1 to 4 heteroatoms selected from an oxygen atom, a nitrogen atom, and a sulfur atom; X represents a group represented by the following formula: —CH2—, —CH2—CH2—, —CH2—CH2—CH2—, or —CH2—O—CH2—; and Z represents a hydrogen atom or a hydroxyl group.
    Type: Application
    Filed: June 27, 2019
    Publication date: October 14, 2021
    Applicant: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Natsuki ISHIDA, Yuji TABATA, Takashi MATSUHIRA, Keiji TAMURA, Takeru YAMAKAWA, Satoshi ISSHIKI, Yoshinari WAKIYAMA, Shohei OUCHI
  • Publication number: 20210155630
    Abstract: Provided are crystals of 1-((2-(3,6-diazabicyclo[3.1.
    Type: Application
    Filed: June 27, 2019
    Publication date: May 27, 2021
    Inventors: KO KUMURA, KEIJI TAMURA, TAKASHI WATANABE, MICHIKO TAKAHASHI
  • Patent number: 10669283
    Abstract: A compound represented by the general formula (1) below or a pharmacologically acceptable salt thereof: [In the formula (1), R1 and R2 may be the same or different and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a carboxy group, a cyano group, an optionally substituted C1-6 alkyl group et al.; R3 represents a hydrogen atom; R4 represents an optionally substituted 4- to 10-membered monocyclic heterocyclic group containing 1 to 4 heteroatoms selected from an oxygen atom, a nitrogen atom, and a sulfur atom; X represents a group represented by the following formula: —CH2—, —CH2—CH2—, —CH2—CH2—CH2—, or —CH2—O—CH2—; and Z represents a hydrogen atom or a hydroxyl group].
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: June 2, 2020
    Assignee: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Keiji Tamura, Takeru Yamakawa, Satoshi Isshiki, Yoshinari Wakiyama, Shohei Ouchi, Takashi Matsuhira, Natsuki Ishida, Yuji Tabata
  • Patent number: 10535497
    Abstract: An electron microscope for observation by illuminating an electron beam on a specimen, includes: an edge element disposed in a diffraction plane where a direct beam not diffracted by but transmitted through the specimen converges or a plane equivalent to the diffraction plane; and a control unit for controlling the electron beam or the edge element. The edge element includes a blocking portion for blocking the electron beam, and an aperture for allowing the passage of the electron beam. The aperture is defined by an edge of the blocking portion in a manner that the edge surrounds a convergence point of the direct beam in the diffraction plane. The control unit varies contrast of an observation image by shifting, relative to the edge, the convergence point of the direct beam along the edge while maintaining a predetermined distance between the convergence point of the direct beam and the edge.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: January 14, 2020
    Assignee: HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Hirokazu Tamaki, Ken Harada, Keiji Tamura, Yoshifumi Taniguchi, Hiroto Kasai, Toshie Yaguchi, Takafumi Yotsuji
  • Publication number: 20190322686
    Abstract: A compound represented by the general formula (1) below or a pharmacologically acceptable salt thereof: [In the formula (1), R1 and R2 may be the same or different and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a carboxy group, a cyano group, an optionally substituted C1-6 alkyl group et al.; R3 represents a hydrogen atom; R4 represents an optionally substituted 4- to 10-membered monocyclic heterocyclic group containing 1 to 4 heteroatoms selected from an oxygen atom, a nitrogen atom, and a sulfur atom; X represents a group represented by the following formula: —CH2—, —CH2—CH2—, —CH2—CH2—CH2—, or —CH2—O—CH2—; and Z represents a hydrogen atom or a hydroxyl group.
    Type: Application
    Filed: December 26, 2017
    Publication date: October 24, 2019
    Applicant: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Keiji TAMURA, Takeru YAMAKAWA, Satoshi ISSHIKI, Yoshinari WAKIYAMA, Shohei OUCHI, Takashi MATSUHIRA, Natsuki ISHIDA, Yuji TABATA
  • Publication number: 20190131107
    Abstract: An electron microscope for observation by illuminating an electron beam on a specimen, includes: an edge element disposed in a diffraction plane where a direct beam not diffracted by but transmitted through the specimen converges or a plane equivalent to the diffraction plane; and a control unit for controlling the electron beam or the edge element. The edge element includes a blocking portion for blocking the electron beam, and an aperture for allowing the passage of the electron beam. The aperture is defined by an edge of the blocking portion in a manner that the edge surrounds a convergence point of the direct beam in the diffraction plane. The control unit varies contrast of an observation image by shifting, relative to the edge, the convergence point of the direct beam along the edge while maintaining a predetermined distance between the convergence point of the direct beam and the edge.
    Type: Application
    Filed: August 22, 2016
    Publication date: May 2, 2019
    Inventors: Hirokazu TAMAKI, Ken HARADA, Keiji TAMURA, Yoshifumi TANIGUCHI, Hiroto KASAI, Toshie YAGUCHI, Takafumi YOTSUJI
  • Patent number: 9139609
    Abstract: A macrolide compound represented by the formula (I) effective against erythromycin resistant bacteria (for example, resistant pneumococci, streptococci and mycoplasmas).
    Type: Grant
    Filed: February 20, 2012
    Date of Patent: September 22, 2015
    Assignees: TAISHO PHARMACEUTICAL CO., LTD., MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Tomohiro Sugimoto, Naoki Sasamoto, Jun Kurosaka, Masato Hayashi, Kanako Yamamoto, Masato Kashimura, Yasunobu Ushiki, Haruhisa Ogita, Tomoaki Miura, Kenichi Kanemoto, Kou Kumura, Satoshi Yoshida, Keiji Tamura, Eiki Shitara
  • Patent number: 8669535
    Abstract: The present invention has an object to provide a cold cathode field-emission electron gun with low aberration, to thereby provide a high-brightness electron gun even in the case of a large current. The present invention provides a field-emission electron gun which extracts an electron beam from a cathode and converges the extracted electron beam, the field-emission electron gun including: a magnetic field lens which is provided such that the cathode is disposed inside of a magnetic field of the lens; and an extraction electrode for extracting electrons from the cathode, the extraction electrode being formed into a cylindrical shape without an aperture structure. The present invention can provide an electron gun having a function of converging an electron beam using a magnetic field, the electron gun which is capable of reducing an incidental electrostatic lens action and has small aberration and high brightness.
    Type: Grant
    Filed: April 14, 2010
    Date of Patent: March 11, 2014
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Mikio Ichihashi, Takashi Onishi, Shunichi Watanabe, Keiji Tamura
  • Publication number: 20140046043
    Abstract: A macrolide compound represented by the formula (I) effective against erythromycin resistant bacteria (for example, resistant pneumococci, streptococci and mycoplasmas).
    Type: Application
    Filed: February 20, 2012
    Publication date: February 13, 2014
    Applicants: MEIJI SEIKA PHARMA CO., LTD., TAISHO PHARMACEUTICAL CO., LTD.
    Inventors: Tomohiro Sugimoto, Naoki Sasamoto, Jun Kurosaka, Masato Hayashi, Kanako Yamamoto, Masato Kashimura, Yasunobu Ushiki, Haruhisa Ogita, Tomoaki Miura, Kenichi Kanemoto, Kou Kumura, Satoshi Yoshida, Keiji Tamura, Eiki Shitara
  • Publication number: 20120062094
    Abstract: The present invention has an object to provide a cold cathode field-emission electron gun with low aberration, to thereby provide a high-brightness electron gun even in the case of a large current. The present invention provides a field-emission electron gun which extracts an electron beam from a cathode and converges the extracted electron beam, the field-emission electron gun including: a magnetic field lens which is provided such that the cathode is disposed inside of a magnetic field of the lens; and an extraction electrode for extracting electrons from the cathode, the extraction electrode being formed into a cylindrical shape without an aperture structure. The present invention can provide an electron gun having a function of converging an electron beam using a magnetic field, the electron gun which is capable of reducing an incidental electrostatic lens action and has small aberration and high brightness.
    Type: Application
    Filed: April 14, 2010
    Publication date: March 15, 2012
    Inventors: Mikio Ichihashi, Tadashi Onishi, Shunichi Watanabe, Keiji Tamura
  • Publication number: 20090218508
    Abstract: The present invention provides an electron beam instrument in which variation of the trajectory of the electron beams can be suppressed even when the voltage applied to the first extractor electrode is controlled in order to stabilize the emission current amount of the electron beams. The electron beam instrument has a cold cathode field emission electron gun. The cold cathode field emission electron gun has a cold cathode, a first extractor electrode and a second extractor electrode. Distance between the cold cathode and the first extractor electrode is set to be shorter than distance between the first extractor electrode and the second extractor electrode. Voltage applied to the first extractor electrode is increased when current amount of the electron beams emitted from the cold cathode is attenuated.
    Type: Application
    Filed: February 25, 2009
    Publication date: September 3, 2009
    Inventors: Keiji TAMURA, Shun-ichi WATANABE, Takashi ONISHI
  • Patent number: 6333160
    Abstract: A method for objectively assessing and monitoring the relative health and homeostatic balance of a group of animals or the individual animals in the group as a basis for animal management decisions is provided. The objective assessment and monitoring method quantitatively determines the upper limit of normal for &agr;1-acid glycoprotein values in a selected body fluid of a selected species of animals. The &agr;1-acid glycoprotein levels of the animals to be evaluated are quantitatively determined and compared with the normal &agr;1-acid glycoprotein upper limit to identify animals whose immune systems or health has been compromised by stress or disease to provide a basis for animal management decisions to promote and maintain the optimum health and well being of the group.
    Type: Grant
    Filed: March 31, 1993
    Date of Patent: December 25, 2001
    Inventor: Keiji Tamura
  • Patent number: 5559211
    Abstract: A biologically active, stable protein with a molecular weight of 20,000 to 30,000 and an isoelectric point of 8.0-10.0 is produced from the culture fluid of Streptococcus pyogenes and purified. The purified biologically active protein produces lymphocyte proliferation, provides protection against bacterial and viral infection and restricts minor metastasis.
    Type: Grant
    Filed: February 18, 1994
    Date of Patent: September 24, 1996
    Assignee: Kabushiki Kaisha Saikin Kagaku Kenkyujo
    Inventors: Katsuo Kumagai, Hidemi Rikiishi, Keiji Tamura, Shunji Sugawara, Eiji Nemoto, Shigefumi Okamoto, Tokio Onta
  • Patent number: 5547329
    Abstract: A roller bottle handling system includes a culture rack storage station for storing a plurality of culture racks each for accommodating a plurality of roller bottles each filled with a culture medium and cells, and a mass-handling facility for extracting completed cultures from roller bottles and replacing a culture medium in the roller bottles with a new culture medium. The roller bottle handling system further includes an unloading station for taking out roller bottles from culture racks delivered from the culture rack storage station and delivering the roller bottles to the mass-handling facility, and a loading station for charging roller bottles filled with a culture medium and cells into culture racks. Automatic guided vehicles or overhead traveling cranes are movable to deliver culture racks, one at a time, between the culture rack storage station and the unloading and loading stations.
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: August 20, 1996
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Osamu Hirai, Keiji Tamura, Hajime Ichihashi
  • Patent number: 5085944
    Abstract: A rare-earth metal series alloy for storage of hydrogen is represented by a general formula of Rem.sub.1 Ni.sub.w Al.sub.x Fe.sub.y M.sub.z as an atomic ratio (wherein Rem is at least one rare earth element such as Mischmetal, M is at least one of Cu, Nb, Si and Zr, and 2.5<w<5.5, 0<x<2.0, 0<y<2.0, 0<z<2.0 and 4.0.ltoreq.w+x+y+z.ltoreq.6.0). Further, the alloy is coated with a film of at least one of Pd, Cu and Ni having a thickness of 100-1000 .ANG..
    Type: Grant
    Filed: July 27, 1990
    Date of Patent: February 4, 1992
    Assignee: Nippon Yakin Kogyo Co., Ltd.
    Inventors: Kazuo Ebato, Keiji Tamura
  • Patent number: 4661415
    Abstract: A zirconium alloy having a plateau region of equilibrium hydrogen dissociation pressure and a small hysteresis, whose hydrogen dissociation pressure is in a range of 0.6 to 3 atm at 20.degree. C., 1 to 5 atm at 40.degree. C., and 1 to 17 atm at 80.degree. C., the activation of which can be effected according to a single procedure of vacuum evacuation at room temperature and pressurization under a hydrogen pressure of 30 atm at room temperature, and which is comparable or superior in the rates of hydrogen absorption and release, the maximum hydrogen absorbing capacity and effective hydrogen releasing capacity to conventional zirconium alloys. A hydrogen absorbing and releasing material comprising an alloy as mentioned above and thin films of one element selected from Pd, Cu, and Ni, which allows only hydrogen to permeate, and covering the surfaces of particles of the alloy.
    Type: Grant
    Filed: October 22, 1985
    Date of Patent: April 28, 1987
    Assignee: Nihon Yakin Kogyo Kabushiki Kaisha
    Inventors: Kazuo Ebato, Yasuaki Osumi, Keiji Tamura, Hiroshi Yoshida
  • Patent number: 4269765
    Abstract: The present invention provides a method for the preparation of a specific immune serum by immunizing IAP in animals other than humans and absorbing the thus obtained serum with normal human serum.
    Type: Grant
    Filed: March 30, 1978
    Date of Patent: May 26, 1981
    Assignees: Kabushiki Kaisha Saikin Kagaku Kenkyujo, Kabushiki Kaisha Kayaku Kosei Bushitsu Kenkyujo
    Inventors: Yoshiji Matsuda, Keiji Tamura, Hiroaki Motoki, Fumio Kitame, Nakao Ishida