Patents by Inventor Keiko Doi

Keiko Doi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitory RNA for modulating the molecular function of ZFAT gene
    Patent number: 8580562
    Abstract: The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention is a siRNA comprising a sense RNA having a base sequence of contiguous 20 to 20 bases, preferably 23 to 27 bases, of ZFAT mRNA and an anti-sense RNA having a base sequence complementary to the base sequence of the sense RNA or a shRNA comprising a double-stranded RNA (dsRNA) with the sense RNA connected to the anti-sense RNA via a loop sequence. The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention decreases a rate of cell proliferation of cancer cells, etc., induces apoptosis of cells including cancer cells, or inhibits an immunoresponse by inhibiting the expression of the ZFAT gene. Therefore, the inhibitory RNA of this invention is useful for development of molecular target agents particularly for cancer cells or immunosuppressive agents.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: November 12, 2013
    Assignee: Fukuoka University
    Inventors: Senji Shirasawa, Takahiro Fujimoto, Toshiyuki Tsunoda, Keiko Doi, Midori Koyanagi
  • INHIBITORY RNA FOR MODULATING THE MOLECULAR FUNCTION OF ZFAT GENE
    Publication number: 20110237647
    Abstract: The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention is a siRNA comprising a sense RNA having a base sequence of contiguous 20 to 20 bases, preferably 23 to 27 bases, of ZFAT mRNA and an anti-sense RNA having a base sequence complementary to the base sequence of the sense RNA or a shRNA comprising a double-stranded RNA (dsRNA) with the sense RNA connected to the anti-sense RNA via a loop sequence. The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention decreases a rate of cell proliferation of cancer cells, etc., induces apoptosis of cells including cancer cells, or inhibits an immunoresponse by inhibiting the expression of the ZFAT gene. Therefore, the inhibitory RNA of this invention is useful for development of molecular target agents particularly for cancer cells or immunosuppressive agents.
    Type: Application
    Filed: September 8, 2008
    Publication date: September 29, 2011
    Applicant: FUKUOKA UNIVERSITY
    Inventors: Senji Shirasawa, Takahiro Fujimoto, Toshiyuki Tsunoda, Keiko Doi, Midori Koyanagi
  • Toy figurine
    Patent number: D373799
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: September 17, 1996
    Assignee: Tomy Company, Ltd.
    Inventors: Keiko Doi, Masatsune Sasaki
  • Toy figurine
    Patent number: D373801
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: September 17, 1996
    Assignee: Tomy Company, Ltd.
    Inventors: Keiko Doi, Masatsune Sasaki
  • Toy figurine
    Patent number: D373802
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: September 17, 1996
    Assignee: Tomy Company, Ltd.
    Inventors: Keiko Doi, Masatsune Sasaki
  • Toy figurine
    Patent number: D374044
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: September 24, 1996
    Assignee: Tomy Company, Ltd.
    Inventors: Keiko Doi, Masatsune Sasaki
  • Motorized block for toy
    Patent number: D382025
    Type: Grant
    Filed: April 25, 1995
    Date of Patent: August 5, 1997
    Assignee: Tomy Company Ltd.
    Inventors: Keiko Doi, Masatsune Sasaki