Patents by Inventor Keiko Fukamachi

Keiko Fukamachi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5217699
    Abstract: A calcium-phosphate type hydroxyapatite for chromatographic separation is in the form of spherulites having a mean particle diameter of 0.5 to 50 .mu.m, preferably 1 to 10 .mu.m. The spherulites are each an aggregate mainly of acicular crystallites belonging to a series of hexagonal systems and having unit lattice constants of 9.58.+-.0.08 .ANG. for the a axis and 7.00.+-.0.05 .ANG. for the c axis. The hydroxyapatite is produced by granulating a calcium=phosphate type hydroxyapatite in the form of a gel and then firing the granular apatite at 400.degree. to 700.degree. C., preferably at 500.degree. to 600.degree. C. The firing is performed by heating the granules in the presence of oxygen or air for a given period of time.
    Type: Grant
    Filed: July 17, 1991
    Date of Patent: June 8, 1993
    Assignees: Toa Nenryo Kogyo Kabushiki Kaisha, Ashaikogaku Kogyo Kabushiki Kaisha
    Inventors: Nobuaki Tagaya, Hideyuki Kuwakara, Takao Hashimoto, Noriko Komatsu, Keiko Fukamachi, Tsugio Maeshima, Toshihiro Ishikawa, Tetsuro Ogawa
  • Patent number: 5082566
    Abstract: A calcium-phosphate type hydroxyapatite for chromatographic separation is in the form of spherulites having a mean particle diameter of 0.5 to 50 .mu.m, preferably 1 to 10 .mu.m. The spherulites are each an aggregate mainly of acicular crystallites belonging to a series of hexagonal systems and having unit lattice constants of 9.58.+-.0.08 .ANG. for the a axis and 7.00.+-.0.05 .ANG. for the c axis. The hydroxyapatite is produced by granulating a calcium-phosphate type hydroxyapatite in the form of a gel and then firing the granular apatite at 400.degree. to 700.degree. C., preferably at 500.degree. to 600.degree. C. The firing is performed by heating the granules in the presence of oxygen or air for a given period of time.
    Type: Grant
    Filed: September 12, 1988
    Date of Patent: January 21, 1992
    Assignees: Toa Nenryo Kogyo Kabushiki Kaisha, Asahi Kogaku Kogyo Kabushiki Kaisha
    Inventors: Nobuaki Tagaya, Hideyuki Kuwahara, Takao Hashimoto, Noriko Komatsu, Keiko Fukamachi, Tsugio Maeshima, Toshihiro Ishikawa, Tetsuro Ogawa
  • Patent number: 5037543
    Abstract: An assemblage of hydroxyl apatite particles having small and uniform particle size. The median of the particle size is 1 to 10 .mu.m, and at least 90% of the particles in the assemblage have a particle size of not more than 25 .mu.m. The assemblage can be used to pack a liquid chromatography column.
    Type: Grant
    Filed: July 9, 1990
    Date of Patent: August 6, 1991
    Assignee: Toa Nenryo Kogyo K.K.
    Inventors: Tsugio Maejima, Kimio Tamai, Tetsuo Kanakubo, Masao Yoshizawa, Nobuaki Tagaya, Hideyuki Kuwahara, Takao Hashimoto, Noriko Komatsu, Keiko Fukamachi
  • Patent number: 4794171
    Abstract: A calcium-phosphate type hydroxyapatite which belongs to a series of hexagonal systems has unit lattice constants of 9.58.+-.0.08 .ANG. for the a axis and 7.00.+-.0.05 .ANG. for the c axis. Its Ca/P ratio is in the range of 1.50 to 1.90. It is for use as a column packing material for chromatographic separation of biopolymers. The hydroxyapatite is produced by firing it in the form of a gel or powder at a temperature of 400.degree. to 700.degree. C. As a gel the hydroxyapatite takes the form of a suspension or slurry. A powder is prepared by removing moisture from the hydroxyapatite in the gel form and then drying. Either gel or powder is fired by heating in the presence of oxygen or air at 500.degree. to 600.degree.0 C.
    Type: Grant
    Filed: September 22, 1986
    Date of Patent: December 27, 1988
    Assignee: Toa Nenryo Kogyo Kabushiki Kaisha
    Inventors: Nobuaki Tagaya, Hideyuki Kuwahara, Takao Hashimoto, Noriko Komatsu, Keiko Fukamachi, Tsugio Maeshima
  • Patent number: 4781904
    Abstract: A calcium-phosphate type hydroxyapatite for chromatographic separation is in the form of spherulites having a mean particle diameter of 0.5 to 50 .mu.m, preferably 1 to 10 .mu.m. The spherulites are each an aggregate mainly of acicular crystallites belonging to a series of hexagonal systems and having unit lattice constants of 9.58.+-.0.08 .ANG. for the a axis and 7.00.+-.0.05 .ANG. for the c axis. The hydroxyapatite is produced by granulating a calcium-phosphate type hydroxyapatite in the form of a gel and then firing the granular apatite at 400.degree. to 700.degree. C., preferably at 500.degree. to 600.degree. C. The firing is performed by heating the granules in the presence of oxygen or air for a given period of time.
    Type: Grant
    Filed: September 22, 1986
    Date of Patent: November 1, 1988
    Assignees: Tao Nenryo Kogyo Kabushiki Kaisha, Asahi Kogaku Kogyo Kabushiki Kaisha
    Inventors: Nobuaki Tagaya, Hideyuki Kuwahara, Takao Hashimoto, Noriko Komatsu, Keiko Fukamachi, Tsugio Maeshima, Toshihiro Ishikawa, Tetsuro Ogawa