Patents by Inventor Keiko Kamei

Keiko Kamei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods useful for the diagnosis and treatment of heparin induced thrombocytopenia/thrombosis
    Patent number: 7728115
    Abstract: The invention includes compositions, kits and methods comprising a monoclonal antibody which shares key functional properties with the polyclonal antibodies which participate in the pathogenesis of heparin induced thrombocytopenia/thrombosis (HIT/HITT) in a mammal. The monoclonal antibody of the invention preferentially binds with a PF4/heparin complex relative to the binding of the antibody with PF4 or heparin alone. The monoclonal antibody of the invention also binds specifically with PF4 in a complex with other glycosaminoglycans besides heparin, and also activates platelets. The monoclonal antibody of the invention is useful in methods for diagnosing and treating HIT/HITT in a mammal. A humanized version of the monoclonal antibody of the invention is also included, along with a process for humanizing the monoclonal antibody of the invention.
    Type: Grant
    Filed: August 2, 2005
    Date of Patent: June 1, 2010
    Assignee: STC. UNM
    Inventors: Gowthami M. Arepally, Walter Kisiel, Keiko Kamei, Shintaro Kamei
  • Compositions and methods useful for the diagnosis and treatment of heparin induced thrombocytopenia/thrombosis
    Publication number: 20060040323
    Abstract: The invention includes compositions, kits and methods comprising a monoclonal antibody which shares key functional properties with the polyclonal antibodies which participate in the pathogenesis of heparin induced thrombocytopenia/thrombosis (HIT/HITT) in a mammal. The monoclonal antibody of the invention preferentially binds with a PF4/heparin complex relative to the binding of the antibody with PF4 or heparin alone. The monoclonal antibody of the invention also binds specifically with PF4 in a complex with other glycosaminoglycans besides heparin, and also activates platelets. The monoclonal antibody of the invention is useful in methods for diagnosing and treating HIT/HITT in a mammal. A humanized version of the monoclonal antibody of the invention is also included, along with a process for humanizing the monoclonal antibody of the invention.
    Type: Application
    Filed: August 2, 2005
    Publication date: February 23, 2006
    Applicant: SCIENCE & TECHNOLOGY CORPORATION @ UNM
    Inventors: Gowthami Arepally, Walter Kisiel, Keiko Kamei, Shintaro Kamei
  • Compositions and methods useful for the diagnosis and treatment of heparin induced thrombocytopenia/thrombosis
    Patent number: 6964854
    Abstract: The invention includes compositions, kits and methods comprising a monoclonal antibody which shares key functional properties with the polyclonal antibodies which participate in the pathogenesis of heparin induced thrombocytopenia/thrombosis (HIT/HITT) in a mammal. The monoclonal antibody of the invention preferentially binds with a PF4/heparin complex relative to the binding of the antibody with PF4 or heparin alone. The monoclonal antibody of the invention also binds specifically with PF4 in a complex with other glycosaminoglycans besides heparin, and also activates platelets. The monoclonal antibody of the invention is useful in methods for diagnosing and treating HIT/HITT in a mammal. A humanized version of the monoclonal antibody of the invention is also included, along with a process for humanizing the monoclonal antibody of the invention.
    Type: Grant
    Filed: July 13, 2000
    Date of Patent: November 15, 2005
    Assignee: Science & Technology Corporation
    Inventors: Gowthami M. Arepally, Walter Kisiel, Keiko Kamei, Shintaro Kamei