Patents by Inventor Keiko Kashiwagi

Keiko Kashiwagi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR DETERMINATION OF STROKE AND/OR CEREBRAL INFARCTION USING 3-HPMA AS MEASURE
    Publication number: 20140208835
    Abstract: Provided is a novel assessment method for stroke and cerebral infarction (in particular, asymptomatic cerebral infarction) without any burden on a subject to be tested. It is newly found that the content of 3-HPMA, which is a metabolite of acrolein, in a urine specimen decreases in a stroke patient as compared to a healthy subject without history of stroke, irrespective of smoking habits and gender, which is quite different from the result expected from a conventional finding. Thus, an assessment method for stroke and/or cerebral infarction, including using 3-HPMA in a urine specimen as an indicator, is completed.
    Type: Application
    Filed: June 12, 2012
    Publication date: July 31, 2014
    Applicant: Amine Pharma Research Institute Co., Ltd.
    Inventors: Kazuei Igarashi, Keiko Kashiwagi, Madoka Yoshida, Mutsumi Mizoi, Ryotaro Saiki
  • Method of diagnosing apoplectic stroke/asymptomatic brain infarction using acrolein content
    Patent number: 8715921
    Abstract: The present invention provides a diagnostic method for stroke/asymptomatic cerebral infarction and a screening method for patients with stroke/asymptomatic cerebral infarction, which comprise measuring acrolein content or polyamine content; or polyamine oxidase activity or protein content of polyamine oxidase in plasma. The knowledge of the present invention indicates the possibility of preventing, inhibiting the progression of stroke/asymptomatic cerebral infarction by inhibiting polyamine oxidase, and the possibility of obtaining a therapeutic agent for stroke/asymptomatic cerebral infarction by searching for compounds that inhibit polyamine oxidase.
    Type: Grant
    Filed: March 25, 2005
    Date of Patent: May 6, 2014
    Inventors: Kazuei Igarashi, Shiro Ueda, Naokatsu Saeki, Keiko Kashiwagi, Hideyuki Tomitori
  • Method of Diagnosing Apoplectic Stroke/Asymptomatic Brain Infarction Using Polyamine and Acrolein Contents, Polyamine Oxidase Activity or Protein Content Thereof as Indication
    Publication number: 20080254495
    Abstract: The present invention provides a diagnostic method for stroke/asymptomatic cerebral infarction and a screening method for patients with stroke/asymptomatic cerebral infarction, which comprise measuring acrolein content or polyamine content; or polyamine oxidase activity or protein content of polyamine oxidase in plasma. The knowledge of the present invention indicates the possibility of preventing, inhibiting the progression of stroke/asymptomatic cerebral infarction by inhibiting polyamine oxidase, and the possibility of obtaining a therapeutic agent for stroke/asymptomatic cerebral infarction by searching for compounds that inhibit polyamine oxidase.
    Type: Application
    Filed: March 25, 2005
    Publication date: October 16, 2008
    Applicant: FUENCE CO., LTD.
    Inventors: Kazuel Igarashi, Shiro Ueda, Naokatsu Saeki, Keiko Kashiwagi, Hideyuki Tomitori