Patents by Inventor Keiko Koh

Keiko Koh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing imidazole derivative
    Patent number: 6005105
    Abstract: The present invention is directed to a process for preparing the following compound ##STR1## which is prepared starting from ##STR2## which is reacted succesively with 4-iodobenzyl or 4-bromobenzyl bromide, hydrazine and 1,4-dimethyl-1,3-cyclohexadiene, reduced and reacted with phenyltetrazole or suitably protected phenyltetrazole followed by removal
    Type: Grant
    Filed: December 6, 1995
    Date of Patent: December 21, 1999
    Assignee: Pharmacia & Upjohn Company
    Inventors: Hiroyoshi Yamada, Kiyotaka Munesada, Keiko Koh, Kazuo Tsuzuki, Mikio Taniguchi, Yoshiji Fujita
  • Imidazobenzoquinones and composition for preventing or treating hypertension or congestive heart failure containing the same
    Patent number: 5506361
    Abstract: There are provided pharmacologically active compounds which are highly effective to treat hypertension or congestive heart failure, and are well absorbed into the body and have long-lasting action. Thus, the present invention providesA compound represented by the general formula: ##STR1## or a pharmacologically acceptable ester or salt thereof, and a pharmaceutical composition for preventing or treating hypertension or congestive heart failure which comprises the compound as an active ingredient.
    Type: Grant
    Filed: October 21, 1993
    Date of Patent: April 9, 1996
    Assignee: TheUpjohn Company
    Inventors: Keiko Koh, Hiroshi Kushida, Noriie Itoh, Kazunori Ozawa, William W. McWhorter, Jr.
  • Imidazole derivatives and pharmaceutical compositions containing the same
    Patent number: 5442062
    Abstract: The present invention provides a novel imidazole derivative having the chemical formula ##STR1## These compounds are useful for preventing or treating hypertension or congestive heart failure and have high activity, rapid action upon intravenous injection, good oral absorbtion, low toxicity, and long-lasting action. Also provided are pharmaceutical compositions which contain these compounds.
    Type: Grant
    Filed: April 22, 1994
    Date of Patent: August 15, 1995
    Assignee: The Upjohn Company
    Inventors: Keiko Koh, Mikio Taniguchi, Noriie Itoh, Hiroshi Kushida, Osamu Morita, Hiroyoshi Yamada, Kiyotaka Munesada, Kazuo Tsuzuki, Mineo Kunihara, Yoshiji Fujita