Patents by Inventor Keiko Morikubo

Keiko Morikubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11781991
    Abstract: An object of the present invention is to provide a simple method of detecting a protein in a liquid, which requires less labor or cost as compared with a conventional method. In the present invention, it has been found that coloring a protein by a color reaction specific to the protein, performing filtration using a filter which easily adsorbs a protein to concentrate the protein on the filter, and checking coloration allows for simply and easily detecting and measuring a protein. In addition, it has been found that filtering a protein using a filter, concentrating the protein on the filter, then coloring the protein by a color reaction specific to the protein, and checking the protein allows simply and easily detecting and measuring a protein.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: October 10, 2023
    Assignee: MEIJI CO., LTD.
    Inventors: Akihiro Nakajima, Keiko Morikubo
  • Publication number: 20200371036
    Abstract: An object of the present invention is to provide a simple method of detecting a protein in a liquid, which requires less labor or cost as compared with a conventional method. In the present invention, it has been found that coloring a protein by a color reaction specific to the protein, performing filtration using a filter which easily adsorbs a protein to concentrate the protein on the filter, and checking coloration allows for simply and easily detecting and measuring a protein. In addition, it has been found that filtering a protein using a filter, concentrating the protein on the filter, then coloring the protein by a color reaction specific to the protein, and checking the protein allows simply and easily detecting and measuring a protein.
    Type: Application
    Filed: November 9, 2018
    Publication date: November 26, 2020
    Applicant: MEIJI CO., LTD.
    Inventors: Akihiro NAKAJIMA, Keiko MORIKUBO
  • Patent number: 9675647
    Abstract: The present inventors conducted dedicated studies, and as a result discovered that propionic acid bacteria fermentation products have a preventive/therapeutic effect on functional gastrointestinal disorders in in vitro tests and tests using patients with irritable bowel syndrome, and completed the present invention. Specifically, the present inventors discovered, in in vitro tests, that the products have an effect of increasing the intestinal contraction frequency without changing the intestinal contractile force in a distal colon-specific manner. Moreover, effects of improving the defecation condition, general abdominal condition, and health-related QOL in patients with irritable bowel syndrome were also found. Furthermore, propionic acid bacteria fermentation products can be taken in large amounts. Therefore, the propionic acid bacteria fermentation products can be expected to have an effect of preventing/treating functional gastrointestinal disorders safely.
    Type: Grant
    Filed: January 17, 2008
    Date of Patent: June 13, 2017
    Assignee: MEIJI CO., LTD.
    Inventors: Masayuki Uchida, Shigeru Yamato, Hajime Ariga, Hirotsugu Uehara, Tomofumi Amano, Keiko Morikubo, Kaori Yoshida
  • Patent number: 8241684
    Abstract: The present invention relates to a preventive and/or a therapeutic agent for inflammatory bowel diseases containing a fermentation product of a propionic acid bacterium as an active ingredient.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: August 14, 2012
    Assignee: Meiji Co., Ltd.
    Inventors: Masayuki Uchida, Seiko Narushima, Keiko Morikubo
  • Publication number: 20110257269
    Abstract: The present invention relates to a preventive and/or a therapeutic agent for inflammatory bowel diseases containing a fermentation product of a propionic acid bacterium as an active ingredient.
    Type: Application
    Filed: June 28, 2011
    Publication date: October 20, 2011
    Applicant: MEIJI DAIRIES CORPORATION
    Inventors: Masayuki Uchida, Seiko Narushima, Keiko Morikubo
  • Patent number: 8025911
    Abstract: The present invention relates to a preventive and/or a therapeutic agent for inflammatory bowel diseases containing a fermentation product of a propionic acid bacterium as an active ingredient.
    Type: Grant
    Filed: April 13, 2005
    Date of Patent: September 27, 2011
    Assignee: Meiji Dairies Corporation
    Inventors: Masayuki Uchida, Seiko Narushima, Keiko Morikubo
  • Publication number: 20100040698
    Abstract: The present inventors conducted dedicated studies, and as a result discovered that propionic acid bacteria fermentation products have a preventive/therapeutic effect on functional gastrointestinal disorders in in vitro tests and tests using patients with irritable bowel syndrome, and completed the present invention. Specifically, the present inventors discovered, in in vitro tests, that the products have an effect of increasing the intestinal contraction frequency without changing the intestinal contractile force in a distal colon-specific manner. Moreover, effects of improving the defecation condition, general abdominal condition, and health-related QOL in patients with irritable bowel syndrome were also found. Furthermore, propionic acid bacteria fermentation products can be taken in large amounts. Therefore, the propionic acid bacteria fermentation products can be expected to have an effect of preventing/treating functional gastrointestinal disorders safely.
    Type: Application
    Filed: January 17, 2008
    Publication date: February 18, 2010
    Inventors: Masayuki Uchida, Shigeru Yamato, Hajime Ariga, Hirotsugu Uehara, Tomofumi Amano, Keiko Morikubo, Kaori Yoshida
  • Publication number: 20070196341
    Abstract: The present invention relates to a preventive and/or a therapeutic agent for inflammatory bowel diseases containing a fermentation product of a propionic acid bacterium as an active ingredient.
    Type: Application
    Filed: April 13, 2005
    Publication date: August 23, 2007
    Applicant: MEIJI DAIRIES CORPORATION
    Inventors: Masayuki Uchida, Seiko Narushima, Keiko Morikubo