Patents by Inventor Keiko Ozato

Keiko Ozato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acids encoding mammalian H-2RIIBP or RXR.sub..beta. and uses thereof
    Patent number: 5403925
    Abstract: The present invention relates generally to the identification and characterization of new genes and proteins. More particularly, the present invention relates to the discovery of novel members of the nuclear hormone receptor superfamily and cDNA clones thereof. The family members are designated as H-2RIIBP (or RXR.sub..beta., retinoid x receptors). These proteins bind selectively only to the native region II sequence of the conserved major histocompatibility complex class I regulatory element (MHC CRE). Sequences homologous to the H-2RIIBP gene are found in the nuclear receptor family including: retinoic acid receptors (RAR), estrogen receptors (ER), thyroid hormone receptors (TR), (COUP-TF), and other RXR isoformes.This invention also provides for a diagnostic test which determines the nature and progression of a human tumor by measuring the quantity and quality of H-2RIIBP gene dosage or expression.
    Type: Grant
    Filed: September 28, 1992
    Date of Patent: April 4, 1995
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventor: Keiko Ozato