Patents by Inventor Keinosuke Isono

Keinosuke Isono has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040104135
    Abstract: A vessel is separated into at least two compartments by an easy-open peelable seal. At least one of the separated compartments is constituted of a laminate material. A gas barrier layer is provided to part of the laminate material so that the gas barrier layer may cover the entire surface of that compartment. An example of the vessel includes a vessel in which a laminate material comprised of at least an easy-open peelable material layer and a gas barrier layer is formed into a pouch shape, such that the easy-open peelable material layer is located on the inside of the vessel.
    Type: Application
    Filed: September 22, 2003
    Publication date: June 3, 2004
    Inventors: Kazuhiro Kaneko, Hajime Miyabe, Takashi Matsuo, Tetsuya Tsuruga, Daisuke Misu, Keinosuke Isono
  • Patent number: 6162205
    Abstract: A container for therapeutic use is formed of a main body, which is made of a flexible resin and provided with a bag portion. The bag portion is formed in a flat shape at at least a part thereof where mutually-opposing walls of the bag portion are peelably welded together at inner surfaces thereof to form a welded region. A hole is formed as an attachment hole through at least one of the mutually-opposing walls in the welded region. A holder with a medicament placed therein, said medicament being prone to a change in property or color upon absorption of moisture, is hermetically attached to the at least one wall over the attachment hole to seal the medicament in the holder. A moisture-barrier member with a desiccant placed therein is arranged on a side opposite to the holder so that the other wall of the bag portion is hermetically covered by the moisture-barrier member at a position at least corresponding to the attachment hole.
    Type: Grant
    Filed: October 21, 1998
    Date of Patent: December 19, 2000
    Assignee: Mateial Engineering Technology Laboratory, Incorporated
    Inventors: Hiroyuki Shichi, Takao Yoshida, Tatsuo Suzuki, Keinosuke Isono
  • Patent number: 5871477
    Abstract: A medical container with an electrolyte solution stored therein is disclosed. It is formed of a resinmade container main body, a base solution compartment, at least one isolated compartment or connected compartment, and an openable portion. The base solution compartment is arranged in the container main body and is filled with the electrolyte solution in a state steamsterilized together with the container main body. The isolated compartment or connected compartment is arranged in the container main body, is isolated from the base solution compartment by an isolation wall interposed therebetween, and is filled with a bicarbonate. The openable portion permits aseptic communication between the base solution compartment and the isolated compartment or connected compartment by an operation from an outside of the container main body at the time of use. The openable portion is formed at at least a part of the isolation wall.
    Type: Grant
    Filed: November 27, 1996
    Date of Patent: February 16, 1999
    Assignee: Material Engineering Technology Laboratory, Incorporated
    Inventors: Keinosuke Isono, Hiroyuki Shichi, Hiroshi Motobayashi
  • Patent number: 5662642
    Abstract: An instillator having a medicator-connecting mouth into which a medication that cannot be subjected to sterilization may be introduced by a simple operation and in a germ-free condition so that the medication is mixed with a pharmaceutical liquid contained therein, said instillator being composed of an outlet member, a medicator-connecting mouth and a body, said medicator-connecting mouth comprising a communicating pathway which communicates with the inside of the body upon use, a germ-trapping filter disposed in the middle of said communicating pathway, a sealing means for sealing said communicating pathway disposed between said germ-trapping filter and said body, and a connecting means disposed at one end of said communicating pathway opposite to the body, the body made of a flexible material being filled with a pharmaceutical liquid, sealed and subjected to autoclaved sterilization, the connecting port of the instillator having a connecting duct tightly fitted into the port.
    Type: Grant
    Filed: December 30, 1994
    Date of Patent: September 2, 1997
    Assignee: Material Engineering Technology Laboratory, Inc.
    Inventors: Keinosuke Isono, Tatsuo Suzuki
  • Patent number: 5509898
    Abstract: A therapeutic container is provided for use in a closed therapy system. The therapeutic container is a flexible container that has suspending means, that is divided into a first compartment and a second compartment by an isolation zone, that has an outlet member provided with an openable communication passage which permits communication between the first and second compartments, and that optionally has a second openable communication passage at a location proximal to the end of the container on the side of the suspending means, whereby both the contents of the first and the second compartments can be discharged through the outlet member at a constant mixing ratio while mixing them together.
    Type: Grant
    Filed: May 6, 1994
    Date of Patent: April 23, 1996
    Assignee: Material Engineering Technology Laboratory, Inc.
    Inventors: Keinosuke Isono, Tatsuo Suzuki
  • Patent number: 5423793
    Abstract: The present invention provides a stopper device comprising a stopper-support structure having a passage inside and a stopper accommodated in the-passage so as to block the passage but movably in the passage, as well as an apparatus containing the stopper device, used for mixing of two components. The stopper device can be penetrated with a connecting device with no edge and therefore generates no debris during penetration and reliably prevents leakage of container contents.
    Type: Grant
    Filed: November 23, 1993
    Date of Patent: June 13, 1995
    Assignee: Material Engineering Technology Lab., Inc.
    Inventors: Keinosuke Isono, Tatsuo Suzuki
  • Patent number: 5380315
    Abstract: An apparatus is provided for separately storing and selectively mixing a first component, which is in a liquid form, and a second component. The apparatus is formed of a first container made of a flexible material, having a communication mouth with an isolator and adapted to store the first component therein, a supporting case connected to the communication mouth, a second container having a mouth portion held in the case and a plug fitted in the mouth portion and adapted to store the second component, and a hollow, inflexible communication device capable of penetrating through the isolator and the plug. The communication device is accommodated in the first container and is attached to the communication mouth movably therein.
    Type: Grant
    Filed: January 26, 1993
    Date of Patent: January 10, 1995
    Assignee: Material Engineering Technology Laboratory Incorporated
    Inventors: Keinosuke Isono, Tatsuo Suzuki
  • Patent number: 5114004
    Abstract: Disclosed herein is a filled and sealed, self-contained mixing container. The container has compartments which are isolated from each other. Plural substances which contain components susceptible to mutual reaction unless isolated from each other are contained in the respective compartments. In use, these compartments are communicated together so that the individual contents can be mixed within the container. A flow passage or passages, each of which has an isolator for the contents and is adapted to communicate the compartments with each other, and is formed by a side channel provided on an outer surface of a wall of the container. Mixing of the contents without exposure to the external atmosphere can be realized by irreversible destruction of the isolator upon use. The container is suited particularly for a closed therapy system.
    Type: Grant
    Filed: February 12, 1991
    Date of Patent: May 19, 1992
    Assignee: Material Engineering Technology Laboratory Inc.
    Inventors: Keinosuke Isono, Takao Yoshida, Tatsuo Suzuki
  • Patent number: 5023026
    Abstract: Surface of synthetic resin object is hydrophilicated by irradiation of ultraviolet rays.
    Type: Grant
    Filed: October 23, 1989
    Date of Patent: June 11, 1991
    Assignee: Material Engineering Technology Laboratory, Incorporated
    Inventors: Takao Yoshida, Keinosuke Isono, Tatsuo Suzuki
  • Patent number: 4998400
    Abstract: Disclosed is a medical fluid-filled plastic container which includes (a) a sealed inner envelope of plastic material filled with a medical fluid containing a component subject to deterioration by oxygen, (b) a deoxidizer, and (c) a sealed outer envelope of plastic material enclosing both the medical fluid-filled inner envelope and the deoxidizer, as well as several methods of making such a medical fluid-filled plastic container. This medical fluid-filled plastic container will prevent the medical fluid therein from being deteriorated even if it is subjected to steam sterilization or is stored for a long period of time.
    Type: Grant
    Filed: June 13, 1989
    Date of Patent: March 12, 1991
    Assignee: Material Engineering Technology Laboratory, Incorporated
    Inventors: Tatsuo Suzuki, Keinosuke Isono
  • Patent number: 4933123
    Abstract: A surface treatment method for improving the adhesiveness of a surface of a molded article made of a polyolefin resin with a printing ink, which entails irradiating the surface with an abundance of high-energy ultraviolet radiation from a high-output low-pressure mercury vapor lamp having an envelope made of synthetic quartz glass, and wherein the lamp has a wattage per unit lamp length of about 0.1-0.5 W/mm.
    Type: Grant
    Filed: June 29, 1988
    Date of Patent: June 12, 1990
    Assignee: Material Engineering Technology Laboratory, Incorporated
    Inventors: Takao Yoshida, Keinosuke Isono
  • Patent number: 4872553
    Abstract: Disclosed is a medical fluid-filled plastic container which includes (a) a sealed inner envelope of plastic material filled with a medical fluid containing a component subject to deterioration by oxygen, (b) a deoxidizer, and (c) a sealed outer envelope of plastic material enclosing both the medical fluid-filled inner envelope and the deoxidizer, as well as several methods of making such a medical fluid-filled plastic container. This medical fluid-filled plastic container will prevent the medical fluid therein from being deteriorated even it it is subjected to steam sterilization or is stored for a long period of time.
    Type: Grant
    Filed: December 29, 1987
    Date of Patent: October 10, 1989
    Assignee: Material Engineering Technology Laboratory, Incorporated
    Inventors: Tatsuo Suzuki, Keinosuke Isono
  • Patent number: 4836691
    Abstract: A medical bag and method of manufacturing the bag from a thermoplastic resin by irradiating a ferromagnetic heating element which has been prepositioned between the mouth and receiving portions of the bag and which is caused to generate high frequence-induced heat. During subjection of the heating element to a high frequency magnetic field, the mouth portion and receiving portion of the bag melt about the element so that mouth portion, element and receiving portion are bonded together. This technique can also be suitably used for thermoplastic resins, for example, polyolefin resins, to which conventional high-frequency bonding cannot be applied.
    Type: Grant
    Filed: March 2, 1988
    Date of Patent: June 6, 1989
    Assignee: Material Engineering Technology Laboratory Inc.
    Inventors: Tatsuo Suzuki, Keinosuke Isono
  • Patent number: 4820288
    Abstract: A connector for therapeutic tubing comprising a tubular male connector member made of thermally resistant corrosionproof material, a tubular female connector member made of thermally resistant corrosionproof material and a locking mechanism coupled to the connector members and used for locking the union between the connector members. A medical solution bag device comprises a flexible bag, a flexible tube connected to the bag flexible, a further tube adapted to be connected to the flexible tube and the above mentioned connector for connecting the flexible tube to the further tube.
    Type: Grant
    Filed: January 9, 1987
    Date of Patent: April 11, 1989
    Assignee: Terumo Kabushiki Kaisha
    Inventor: Keinosuke Isono
  • Patent number: 4668217
    Abstract: A connector for therapeutic tubing comprising a tubular male connector member made of thermally resistant corrosionproof material, a tubular female connector member made of thermally resistant corrosionproof material and a locking mechanism coupled to the connector members and used for locking the union between the connector members. A medical solution bag device comprises a flexible bag, a flexible tube connected to the flexible bag, a further tube adapted be connected to the flexible tube and the above mentioned connector for connecting the flexible tube to the further tube.
    Type: Grant
    Filed: October 4, 1985
    Date of Patent: May 26, 1987
    Assignee: Terumo Kabushiki Kaisha
    Inventor: Keinosuke Isono
  • Patent number: 4643715
    Abstract: Medical permeating membranes in a zone through which a body fluid flows, said membranes having lateral surfaces in said zone, comprising permeable membranes of regenerated cellulose and a film of a fat-soluble vitamin and glycerin on said lateral surfaces of said membranes in said zone for flow of body fluid.
    Type: Grant
    Filed: June 24, 1986
    Date of Patent: February 17, 1987
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Keinosuke Isono, Keiji Naoi
  • Patent number: 4634447
    Abstract: A method for the manufacture of an artificial organ having a film of a fat-soluble vitamin deposited on the surfaces of parts of said artificial organ susceptible to contact with body fluid in motion through a zone for flow of said body fluid within said artificial organ, which method is characterized by the steps of causing a solution of said fat-soluble vitamin in an organic solvent to flow into said zone for flow of body fluid within said artificial organ and allowing said parts to be amply wetted with said solution, then discharging an excess of said solution out of said artificial organ, and subsequently drying said solution deposited on said parts thereby expelling said organic solvent from the solution. The invention also provides a method for sterilizing said artificial organ after contact with a physiologically harmless liquid.
    Type: Grant
    Filed: January 14, 1986
    Date of Patent: January 6, 1987
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Keinosuke Isono, Keiji Naoi
  • Patent number: 4588407
    Abstract: An artificial organ is disclosed which has a film of either fat-soluble vitamin or a mixture of fat-soluble vitamin with glycerin deposited on the surfaces of parts of the artificial organ adapted to contact body fluid under treatment in a zone for flow of the body fluid within the artificial organ. Also disclosed is a sterilized artificial organ which has the aforementioned coat further subjected to contact with a physiologically harmless liquid and a treatment for sterilization.
    Type: Grant
    Filed: September 7, 1983
    Date of Patent: May 13, 1986
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Keinosuke Isono, Keiji Naoi
  • Patent number: 4588402
    Abstract: A connector for medical tubing for liquid transfusion includes a short tubular male connector member made of thermally resistant corrosionproof materia; a short tubular female connector member made of thermally resistant corrosionproof material; and a fitting surface portion on the outer surface of an insertion end of the male connector, shaped in the male form and made of a material having a smaller thermal expansion coefficient than the material of a corresponding fitting surface portion on the inner surface of an insertion end of the female connector shaped in the female form. The fitting surface portion of the insertion end shaped in the male form, and the fitting surface portion of the insertion end shaped in the female form, are of relative sizes such as to permit the insertion ends to be connected to and separated from each other by shrink fit utilizing the difference between the thermal expansion coefficients thereof. A medical solution bag device using the connector is also disclosed.
    Type: Grant
    Filed: May 1, 1985
    Date of Patent: May 13, 1986
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Akira Igari, Keinosuke Isono
  • Patent number: 4560382
    Abstract: In a medical container comprising a flexible vessel containing a fluid, inlet means attached to the vessel for admitting another fluid into the vessel, and an outlet, a tubular member is extended through the vessel wall as the inlet means and closed at the outer end with a plugging member to shut off the tubular member channel from the exterior and provided at the inner end with a bacterial filter, the plugging member permitting access to the tubular member channel from the exterior when the other fluid is to be admitted into the vessel. A breakable closure member is further mounted on the inner end of the tubular member to shut off the filter member from the interior space of the vessel, but is breakable to permit the communication of the interior space with the tubular member when the other fluid is to be admitted.
    Type: Grant
    Filed: April 4, 1984
    Date of Patent: December 24, 1985
    Assignee: Terumo Corporation
    Inventor: Keinosuke Isono