Patents by Inventor Keisaku Okada
Keisaku Okada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160325113Abstract: Methods and devices related to the treatment of diseases using phototherapy are described. Some embodiments provide an organic light-emitting diode device, such as a light-emitting device for phototherapy, comprising Ring System 1, Ring System 2, Ring System 3, Ring System 4 or Ring System 5. Methods of treating disease with phototherapy are also described.Type: ApplicationFiled: July 18, 2016Publication date: November 10, 2016Inventors: Sazzadur Rahman Khan, Shijun Zheng, Sheng Li, Amane Mochizuki, Keisaku Okada
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Publication number: 20150087685Abstract: Methods and devices related to the treatment of diseases using phototherapy are described. Some embodiments provide an organic light-emitting diode device, such as a light-emitting device for phototherapy, comprising Ring System 1, Ring System 2, Ring System 3, Ring System 4 or Ring System 5. Methods of treating disease with phototherapy are also described.Type: ApplicationFiled: April 12, 2013Publication date: March 26, 2015Inventors: Sazzadur Rahman Khan, Shijun Zheng, Sheng Li, Amane Mochizuki, Keisaku Okada
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Patent number: 8808879Abstract: Methods and devices related to the treatment of diseases using phototherapy are described. Some embodiments provide an organic light-emitting diode device, such as a light-emitting device for phototherapy, comprising a compound of Formula 1. Methods of treating disease diseases with phototherapy are also described.Type: GrantFiled: July 15, 2011Date of Patent: August 19, 2014Assignee: Nitto Denko CorporationInventors: Amane Mochizuki, Sazzadur Rahman Khan, Shijun Zheng, Keisaku Okada
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Publication number: 20120107264Abstract: Polymers including two or more different recurring units are disclosed herein. Also disclosed herein are methods of using such polymers to deliver nucleic acids to a cell.Type: ApplicationFiled: October 13, 2011Publication date: May 3, 2012Applicant: Nitto Denko CorporationInventors: Padmanabh Chivukula, Jian Liu, Akinobu Soma, Keisaku Okada, Sang Van, Julia Zhu, Nianchun Ma, Chen-Chang Lee, Fu Chen, Lei Yu
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Publication number: 20120094924Abstract: Polymers including two or more different recurring units are disclosed herein. Also disclosed herein are methods of using such polymers to deliver nucleic acids to a cell.Type: ApplicationFiled: October 13, 2011Publication date: April 19, 2012Applicant: Nitto Denko CorporationInventors: Padmanabh Chivukula, Jian Liu, Akinobu Soma, Keisaku Okada, Sang Van, Chen-Chang Lee, Lei Yu
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Publication number: 20120093762Abstract: Polymers including two or more different recurring units are disclosed herein. Also disclosed herein are methods of using such polymers to deliver nucleic acids to a cell.Type: ApplicationFiled: October 13, 2011Publication date: April 19, 2012Applicant: Nitto Denko CorporationInventors: Padmanabh Chivakula, Jian Liu, Sang Van, Akinobu Soma, Keisaku Okada, Lei Yu, Nianchun Ma
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Publication number: 20120015998Abstract: Disclosed herein are compounds represented by a formula: R1—Ar1—X—Ar2—Ar3-Het, wherein R1, Ar1, X, Ar2, Ar3, and Het are described herein. Compositions and light-emitting devices related thereto are also disclosed.Type: ApplicationFiled: July 11, 2011Publication date: January 19, 2012Applicant: Nitto Denko CorporationInventors: Amane Mochizuki, Sazzadur Rahman Khan, Sheng Li, Shijun Zheng, Jensen Cayas, Keisaku Okada, Brett T. Harding
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Publication number: 20120016449Abstract: Methods and devices related to the treatment of diseases using phototherapy are described. Some embodiments provide an organic light-emitting diode device, such as a light-emitting device for phototherapy, comprising a compound of Formula 1. Methods of treating disease diseases with phototherapy are also described.Type: ApplicationFiled: July 15, 2011Publication date: January 19, 2012Applicant: Nitto Denko CorporationInventors: Amane Mochizuki, Sazzadur Rahman Khan, Shijun Zheng, Keisaku Okada
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Publication number: 20110306922Abstract: Some embodiments provide a compound represented by Formula 1. Other embodiments provide an organic light-emitting diode device, such as a light-emitting device for phototherapy, comprising a compound of Formula 1. Other embodiments provide an organic light-emitting device optionally comprising a wavelength convertor. Methods related to the treatment of diseases using phototherapy area also described.Type: ApplicationFiled: June 10, 2011Publication date: December 15, 2011Inventors: Sazzadur Rahman Khan, Amane Mochizuki, Sheng Li, David T. Sisk, Rajesh Mukherjee, Keisaku Okada
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Patent number: 7442682Abstract: Compositions and methods are disclosed for the treatment of diabetes and related diseases using peptides with incretin hormone activity. Preferably, the peptide with incretin hormone activity is GLP-1, exendin or an analog of GLP-1 or exendin. The peptides with incretin hormone activity are administered transepithelially using a transepithelial carrier peptide. The transepithelial peptide contains sufficient amino, guanidine or amidino groups to stimulate transepithelial delivery. In some embodiments, the transepithelial carrier and the peptide with incretin hormone activity are embedded in a pressure sensitive adhesive layer of a plaster or patch.Type: GrantFiled: September 2, 2005Date of Patent: October 28, 2008Assignee: Nitto Denko CorporationInventors: Chieko Kitaura, Kenjiro Minomi, Katsuyuki Okubo, Keisaku Okada, Natsuko Kagehisa, Masashi Kamiyama, Zheng Hou, Jian Liu, Yucheng Song, Lei Yu
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Publication number: 20060084604Abstract: Compositions and methods are disclosed for the treatment of diabetes and related diseases using peptides with incretin hormone activity. Preferably, the peptide with incretin hormone activity is GLP-1, exendin or an analog of GLP-1 or exendin. The peptides with incretin hormone activity are administered transepithelially using a transepithelial carrier peptide. The transepithelial peptide contains sufficient amino, guanidine or amidino groups to stimulate transepithelial delivery. In some embodiments, the transepithelial carrier and the peptide with incretin hormone activity are embedded in a pressure sensitive adhesive layer of a plaster or patch.Type: ApplicationFiled: September 2, 2005Publication date: April 20, 2006Inventors: Chieko Kitaura, Kenjiro Minomi, Katsuyuki Okubo, Keisaku Okada, Natsuko Kagehisa, Masashi Kamiyama, Zheng Hou, Jian Liu, Yucheng Song, Lei Yu
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Publication number: 20060008841Abstract: The present invention provides a method for obtaining an aptamer capable of specifically adsorbing to Verotoxin-1 produced by Enterohemorrhagic Escherichia coli by an in vitro selection method utilizing affinity chromatography, particularly, a method including use of an affinity column immobilizing thereon a peptide having an amino acid sequence of Verotoxin-1, for the affinity chromatography, and a single strand nucleic acid molecule, which is an aptamer capable of specifically adsorbing to Verotoxin-1.Type: ApplicationFiled: September 12, 2005Publication date: January 12, 2006Applicant: Nitto Denko CorporationInventors: Keisaku Okada, Shuji Senda, Akio Kobayashi, Eiichiro Fukusaki, Takeshi Honda, Itaru Yanagihara, Tsuyoshi Nakanishi
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Publication number: 20050282226Abstract: The present invention provides an aptamer capable of specifically adsorbing to bisphenol A suspected to be an endocrine disrupter as a target molecule, a method for obtaining an aptamer capable of specifically adsorbing to bisphenol A by an in vitro selection method utilizing affinity chromatography using a carrier immobilizing bisphenol A, particularly, a method including use of an antagonistic elution buffer containing an amphiprotic organic solvent for elution by the affinity chromatography, and a single-strand nucleic acid molecule which is an aptamer obtained thereby.Type: ApplicationFiled: August 29, 2005Publication date: December 22, 2005Applicant: Nitto Denko CorporationInventors: Keisaku Okada, Shuji Senda, Akio Kobayashi, Eiichiro Fukusaki, Itaru Yanagihara, Tsuyoshi Nakanishi
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Patent number: 6753190Abstract: The present invention relates to an immunological detection method capable of performing detection of an analyte in a test sample, and a kit used therefor. There is provided an immunological detection method for detecting an analyte by using a water-absorbent substrate in which a capture region is positioned in a given region on a surface thereof, the capture region being immobilized with a first immunochemical component capable of specifically binding to the analyte, wherein the detection signal is amplified and a kit used therefor.Type: GrantFiled: February 29, 2000Date of Patent: June 22, 2004Assignee: Nitto Denko CorporationInventors: Keisaku Okada, Takeshi Saika, Shuji Senda, Kenjiro Mori, Ken Sato
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Publication number: 20030119159Abstract: The present invention provides a method for obtaining an aptamer capable of specifically adsorbing to Verotoxin-1 produced by Enterohemorrhagic Escherichia coli by an in vitro selection method utilizing affinity chromatography, particularly, a method including use of an affinity column immobilizing thereon a peptide having an amino acid sequence of Verotoxin-1, for the affinity chromatography, and a single strand nucleic acid molecule, which is an aptamer capable of specifically adsorbing to Verotoxin-1.Type: ApplicationFiled: July 3, 2002Publication date: June 26, 2003Applicant: Nitto Denko CorporationInventors: Keisaku Okada, Shuji Senda, Akio Kobayashi, Eiichiro Fukusaki, Takeshi Honda, Itaru Yanagihara, Tsuyoshi Nakanishi
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Publication number: 20030064530Abstract: The present invention provides an aptamer capable of specifically adsorbing to bisphenol A suspected to be an endocrine disrupter as a target molecule, a method for obtaining an aptamer capable of specifically adsorbing to bisphenol A by an in vitro selection method utilizing affinity chromatography using a carrier immobilizing bisphenol A, particularly, a method including use of an antagonistic elution buffer containing an amphiprotic organic solvent for elution by the affinity chromatography, and a single-strand nucleic acid molecule which is an aptamer obtained thereby.Type: ApplicationFiled: July 3, 2002Publication date: April 3, 2003Applicant: Nitto Denko CorporationInventors: Keisaku Okada, Shuji Senda, Akio Kobayashi, Eiichiro Fukusaki, Itaru Yanagihara, Tsuyoshi Nakanishi
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Publication number: 20020086339Abstract: An immunoassay method comprising bringing an immobilized phase comprising, at different positions on a water-absorbable base material, at least two first immunity substances capable of specifically binding with at least two kinds of assay target substances selected from the group consisting of verotoxin-producing Escherichia coli, verotoxin and human hemoglobin contained in a test sample, into contact with a test sample and a liquid containing labeled immunity substances each comprising a second immunity substance that is labeled with colored particles and capable of binding with said assay target substance, thereby to form an assay target substance-labeled immunity substance complex and to bind said complex with respective first immunity substances at the immobilized phase.Type: ApplicationFiled: January 4, 2002Publication date: July 4, 2002Inventors: Keisaku Okada, Kenjiro Mori, Shuji Senda
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Patent number: 6391652Abstract: An immunoassay method comprising bringing an immobilized phase comprising, at different positions on a water-absorbable base material, at least two first immunity substances capable of specifically binding with at least two kinds of assay target substances selected from the group consisting of verotoxin-producing Escherichia coli, verotoxin and human hemoglobin contained in a test sample, into contact with a test sample and a liquid containing labeled immunity substances each comprising a second immunity substance that is labeled with colored particles and capable of binding with said assay target substance, thereby to form an assay target substance-labeled immunity substance complex and to bind said complex with respective first immunity substances at the immobilized phase.Type: GrantFiled: July 22, 1998Date of Patent: May 21, 2002Assignee: Nitto Denko CorporationInventors: Keisaku Okada, Kenjiro Mori, Shuji Senda
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Publication number: 20010009765Abstract: An immunoassay method comprising bringing an immobilized phase comprising, at different positions on a water-absorbable base material, at least two first immunity substances capable of specifically binding with at least two kinds of assay target substances selected from the group consisting of verotoxin-producing Escherichia coli, verotoxin and human hemoglobin contained in a test sample, into contact with a test sample and a liquid containing labeled immunity substances each comprising a second immunity substance that is labeled with colored particles and capable of binding with said assay target substance, thereby to form an assay target substance-labeled immunity substance complex and to bind said complex with respective first immunity substances at the immobilized phase.Type: ApplicationFiled: July 22, 1998Publication date: July 26, 2001Inventors: KEISAKU OKADA, KENJIRO MORI, SHUJI SENDA