Patents by Inventor Keisuke Fukuchi
Keisuke Fukuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10995143Abstract: The present invention relates to the medical use of antibodies against the FGF receptor 4 (FGFR4) combined with Sorafenib, in particular for the prevention or treatment of hyperproliferative diseases associated with FGFR expression, overexpression or hyperactivity.Type: GrantFiled: February 9, 2017Date of Patent: May 4, 2021Assignees: Daiichi Sankyo Europe GmbH, Daiichi Sankyo Company LimitedInventors: Reimar Abraham, Keisuke Fukuchi
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Publication number: 20210123811Abstract: A temperature sensor detects temperatures of at least two distribution lines and includes a temperature detection unit and a protection member that covers the temperature detection unit. The protection member is provided with a first abutting surface that has a concave shape corresponding to an outer shape of a first distribution line and is in contact with the first distribution line and a second abutting surface that has a concave shape corresponding to an outer shape of a second distribution line and is in contact with the second distribution line.Type: ApplicationFiled: October 22, 2020Publication date: April 29, 2021Inventors: Keisuke Fukuchi, Masanori Sagawa, Masashi Yokoi
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Publication number: 20200362033Abstract: An object of the present invention is to provide a novel anti-CD147 antibody exhibiting potent antitumor efficacy and having excellent safety. Another object of the present invention is to provide a pharmaceutical product comprising such an antibody. Another object of the present invention is to provide a method for treating tumors using the antibody or the pharmaceutical product, for example. The present invention provides a CD147-specific antibody that activates CD147 and exhibits high antitumor efficacy. The present invention provides the anti-CD147 antibody that exhibits high antitumor efficacy independent of effector functions. The present invention provides a pharmaceutical composition comprising such an anti-CD147 antibody. The present invention provides a method for treating tumors using such an anti-CD147 antibody and/or pharmaceutical composition.Type: ApplicationFiled: July 26, 2018Publication date: November 19, 2020Applicant: DAIICHI SANKYO COMPANY, LIMITEDInventors: Keisuke FUKUCHI, Kayoko NANAI, Masato AMANO, Kozo YONEDA, Yusuke TOTOKI, Shoji YAMAMOTO
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Patent number: 10358498Abstract: The present invention relates to novel antibodies against the FGF receptor 4 (FGFR4) and to the medical use thereof, in particular for the diagnosis prevention or treatment of diseases associated with FGFR expression, over expression or hyperactivity.Type: GrantFiled: August 11, 2015Date of Patent: July 23, 2019Assignees: Daiichi Sankyo Europe GmbH, Daiichi Sankyo Company, LimitedInventors: Reimar Abraham, Keisuke Fukuchi, Tanja Lange, Johannes Bange, Ichiro Watanabe, Shinko Hayashi, Toshiaki Ohtsuka
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Publication number: 20190048088Abstract: The present invention relates to the medical use of antibodies against the FGF receptor 4 (FGFR4) combined with Sorafenib, in particular for the prevention or treatment of hyperproliferative diseases associated with FGFR expression, overexpression or hyperactivity.Type: ApplicationFiled: February 9, 2017Publication date: February 14, 2019Inventors: Reimar Abraham, Keisuke Fukuchi
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Publication number: 20160368990Abstract: The present invention relates to an antibody having a therapeutic effect on a tumor. That is, the invention relates to an antibody which binds to B7-H3 to exhibit an antitumor activity. An object of the invention is to provide a pharmaceutical having a therapeutic effect on a tumor. By obtaining an anti-B7-H3 antibody which binds to B7-H3 to exhibit an antitumor activity, a pharmaceutical composition for treating a tumor comprising the antibody and the like are obtained.Type: ApplicationFiled: June 20, 2016Publication date: December 22, 2016Applicant: Daiichi Sankyo Company, LimitedInventors: Shu Takahashi, Tatsuji Matsuoka, Kenji Murakami, Takeshi Takizawa, Kenji Hirotani, Atsushi Urano, Keisuke Fukuchi, Mitsuhiro Yazawa
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Patent number: 9371395Abstract: An antibody exhibiting antitumor activity that binds to B7-H3, a functional fragment of the antibody, a pharmaceutical composition that includes the antibody or the functional fragment, methods for making the antibody or the functional fragment, methods for treating a tumor using the antibody or the functional fragment, and polynucleotides encoding the antibody or the functional fragment.Type: GrantFiled: April 24, 2012Date of Patent: June 21, 2016Assignee: Daiichi Sankyo Company, LimitedInventors: Shu Takahashi, Tatsuji Matsuoka, Kenji Murakami, Takeshi Takizawa, Kenji Hirotani, Atsushi Urano, Keisuke Fukuchi, Mitsuhiro Yazawa
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Patent number: 8700375Abstract: There is provided an electromagnetic coupler that communicates signals by using at least one of a longitudinal electrostatic field and a longitudinal induced electric field. The electromagnetic coupler has a ground conductor, a radiation conductor composed of a plurality of rectangular conductors connected in series, and a feeding point formed at one point in the connection of the plurality of rectangular conductors. The plurality of rectangular conductors are connected such that each pair of adjacent rectangular conductors form an angle other than ? radian, and a length from the feeding point to either end of the radiation conductor is an integral multiple of ?/4 in electrical length with respect to a wavelength ? of a central frequency of a frequency band of interest of the electromagnetic coupler.Type: GrantFiled: March 25, 2011Date of Patent: April 15, 2014Assignee: Hitachi Metals, Ltd.Inventors: Yohei Shirakawa, Keisuke Fukuchi
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Patent number: 8633783Abstract: An electromagnetic coupler has a first conductor pattern and a second conductor pattern separated from the first conductor pattern that are formed in a first plane, a feeding pattern made of a conductor and being connected to a feeing system and a ground made of a conductor and being separated from the feeding pattern that are formed in a second plane, and linear conductors electrically connecting between the first conductor pattern and the feeding pattern, and between the second conductor pattern and the ground, respectively.Type: GrantFiled: October 8, 2010Date of Patent: January 21, 2014Assignees: Hitachi Cable Fine-Tech, Ltd., Hitachi Cable, Ltd.Inventors: Yohei Shirakawa, Keisuke Fukuchi, Haruyuki Watanabe
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Publication number: 20130078234Abstract: An antibody exhibiting antitumor activity that binds to B7-H3, a functional fragment of the antibody, a pharmaceutical composition that includes the antibody or the functional fragment, methods for making the antibody or the functional fragment, methods for treating a tumor using the antibody or the functional fragment, and polynucleotides encoding the antibody or the functional fragment.Type: ApplicationFiled: April 24, 2012Publication date: March 28, 2013Applicant: DAIICHI SANKYO COMPANY, LIMITEDInventors: Shu Takahashi, Tatsuji Matsuoka, Kenji Murakami, Takeshi Takizawa, Kenji Hirotani, Atsushi Urano, Keisuke Fukuchi, Mitsuhiro Yazawa
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Publication number: 20110238398Abstract: There is provided an electromagnetic coupler that communicates signals by using at least one of a longitudinal electrostatic field and a longitudinal induced electric field. The electromagnetic coupler has a ground conductor, a radiation conductor composed of a plurality of rectangular conductors connected in series, and a feeding point formed at one point in the connection of the plurality of rectangular conductors. The plurality of rectangular conductors are connected such that each pair of adjacent rectangular conductors form an angle other than ? radian, and a length from the feeding point to either end of the radiation conductor is an integral multiple of ?/4 in electrical length with respect to a wavelength ? of a central frequency of a frequency band of interest of the electromagnetic coupler.Type: ApplicationFiled: March 25, 2011Publication date: September 29, 2011Inventors: Yohei SHIRAKAWA, Keisuke Fukuchi
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Publication number: 20110109408Abstract: An electromagnetic coupler has a first conductor pattern and a second conductor pattern separated from the first conductor pattern that are formed in a first plane, a feeding pattern made of a conductor and being connected to a feeing system and a ground made of a conductor and being separated from the feeding pattern that are formed in a second plane, and linear conductors electrically connecting between the first conductor pattern and the feeding pattern, and between the second conductor pattern and the ground, respectively.Type: ApplicationFiled: October 8, 2010Publication date: May 12, 2011Applicants: Hitachi Cable Fine Tech, Ltd., Hitachi Cable, Ltd.Inventors: Yohei Shirakawa, Keisuke Fukuchi, Haruyuki Watanabe
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Patent number: 7855056Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.Type: GrantFiled: March 9, 2004Date of Patent: December 21, 2010Assignee: Sankyo Co., Ltd.Inventors: Kimihisa Ichikawa, Shu Takahashi, Toshinori Agatsuma, Keisuke Fukuchi, Takehiro Hirai
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Patent number: 7830321Abstract: An antenna for an ultra wide band telecommunications, provided with a rectangular conductive plate where a bow tie slot is formed, an auxiliary element extended from said rectangular conductive plate above one of two vertical angle parts opposed at a center part of the bow tie slot, a feeding part formed at one of the vertical angle parts, and a grounding part formed at the other vertical angle part.Type: GrantFiled: March 20, 2007Date of Patent: November 9, 2010Assignee: Hitachi Cable, Ltd.Inventor: Keisuke Fukuchi
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Patent number: 7755545Abstract: A small antenna operating in multiple modes including three or more modes. There are provided an antenna that includes a ground conductor having a ground potential, a single feeding point whose one end is formed by a part of the ground conductor, and a plurality of transmission lines to which RF power supplied to the feeding point is input, the transmission lines each radiating electromagnetic waves of three frequencies of three modes into space. These transmission lines comprises a transmission line 41 that is connected to the feeding point at one end and to a branching point at the other end, a transmission line connected between branching points, and transmission lines connected to the branching points. The lengths of the respective transmission lines are set so that impedance matching is performed at the feeding point with respect to a plurality of frequencies. The antenna is formed from an integrated metal plate.Type: GrantFiled: July 29, 2004Date of Patent: July 13, 2010Assignee: Hitachi Cable, Ltd.Inventors: Ken Takei, Tomoyuki Ogawa, Morihiko Ikegaya, Keisuke Fukuchi
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Patent number: 7741447Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.Type: GrantFiled: October 15, 2007Date of Patent: June 22, 2010Assignee: Sankyo Co., Ltd.Inventors: Kimihasa Ichikawa, Shu Takahashi, Toshinori Agatsuma, Keisuke Fukuchi, Takehiro Hirai
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Patent number: 7405705Abstract: A wideband antenna has: a rectangular conductor sheet; a bow-tie-shaped slit formed in the rectangular conductor sheet, the rectangular conductor sheet having two apex portions defined by the bow-tie-shaped slit, the two apex portions being opposite to each other in the middle of the bow-tie-shaped slit; an auxiliary antenna element formed to extend along the bow-tie-shaped slit on both sides of one of the two apex portions; a power-feeding portion formed at the one of the two apex portions; and a grounding portion formed at an other of the two apex portions.Type: GrantFiled: June 22, 2007Date of Patent: July 29, 2008Assignee: Hitachi Cable, Ltd.Inventor: Keisuke Fukuchi
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Publication number: 20080146785Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.Type: ApplicationFiled: October 15, 2007Publication date: June 19, 2008Inventors: Kimihasa Ichikawa, Shu Takahashi, Toshinori Agatsuma, Keisuke Fukuchi, Takehiro Hirai
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Patent number: 7372417Abstract: A wideband antenna has: a rectangular conductor sheet; a bow-tie-shaped slit formed in the rectangular conductor sheet, the rectangular conductor sheet having two apex portions defined by the bow-tie-shaped slit, the two apex portions being opposite to each other in the middle of the bow-tie-shaped slit; an auxiliary antenna element formed to extend along the bow-tie-shaped slit on both sides of one of the two apex portions; a power-feeding portion formed at the one of the two apex portions; and a grounding portion formed at an other of the two apex portions.Type: GrantFiled: June 1, 2006Date of Patent: May 13, 2008Assignee: Hitachi Cable, Ltd.Inventor: Keisuke Fukuchi
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Patent number: 7361340Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.Type: GrantFiled: September 9, 2005Date of Patent: April 22, 2008Assignee: Sankyo Co., Ltd.Inventors: Kimihasa Ichikawa, Shu Takahashi, Toshinori Agatsuma, Keisuke Fukuchi, Takehiro Hirai