Patents by Inventor Keisuke Furukawa
Keisuke Furukawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11948720Abstract: An inductor includes a wire having a generally circular shape in cross section, and the magnetic layer covering the wire, wherein the wire includes a conductive wire and an insulating layer covering the conductive wire, the magnetic layer contains anisotropic magnetic particles and a binder, and includes in a surrounding region of the wire within 1.5 times the radius of the wire, a first region in which the anisotropic magnetic particles are oriented along the circumferential direction of the wire, and a second region in which the anisotropic magnetic particles are oriented along the crossing direction that crosses the circumferential direction, or in which the anisotropic magnetic particles are not oriented.Type: GrantFiled: June 4, 2019Date of Patent: April 2, 2024Assignee: NITTO DENKO CORPORATIONInventors: Yoshihiro Furukawa, Keisuke Okumura
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Publication number: 20240087794Abstract: An inductor including a magnetic layer, and a plurality of wires embedded in the magnetic layer and extending in a longitudinal direction. The plurality of wires are spaced in parallel at predetermined intervals in a direction perpendicular to the longitudinal direction. The magnetic layer includes a plurality of wire disposed portions in which the wires are regularly disposed in parallel to each other, and a margin portion that is disposed between the wire disposed portions adjacent to each other in a parallel direction of the wires and in which the wires are omitted.Type: ApplicationFiled: February 3, 2022Publication date: March 14, 2024Applicant: NITTO DENKO CORPORATIONInventors: Yoshihiro FURUKAWA, Keisuke OKUMURA
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Publication number: 20240071086Abstract: An information processing apparatus (10) includes a time and space information acquisition unit (110) that acquires high-risk time and space information indicating a spatial region with an increased possibility of an accident occurring or of a crime being committed and a corresponding time slot, a possible surveillance target acquisition unit (120) that identifies a video to be analyzed from among a plurality of videos generated by capturing an image of each of a plurality of places, on the basis of the high-risk time and space information, and analyzes the identified video to acquire information of a possible surveillance target, and a target time and space identification unit (130) that identifies at least one of a spatial region where surveillance is to be conducted which is at least a portion of the spatial region or a time slot when surveillance is to be conducted, from among the spatial region and the time slot indicated by the high-risk time and space information, on the basis of the information of theType: ApplicationFiled: November 6, 2023Publication date: February 29, 2024Applicant: NEC CorporationInventors: Junko NAKAGAWA, Ryoma OAMI, Kenichiro IDA, Mika SAITO, Shohzoh NAGAHAMA, Akinari FURUKAWA, Yasumasa OHTSUKA, Junichi FUKUDA, Fumi IKEDA, Manabu MORIYAMA, Fumie EINAGA, Tatsunori YAMAGAMI, Keisuke ` HIRAYAMA, Yoshitsugu KUMANO, Hiroki ADACHI
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Publication number: 20240071087Abstract: An information processing apparatus (10) includes a time and space information acquisition unit (110) that acquires high-risk time and space information indicating a spatial region with an increased possibility of an accident occurring or of a crime being committed and a corresponding time slot, a possible surveillance target acquisition unit (120) that identifies a video to be analyzed from among a plurality of videos generated by capturing an image of each of a plurality of places, on the basis of the high-risk time and space information, and analyzes the identified video to acquire information of a possible surveillance target, and a target time and space identification unit (130) that identifies at least one of a spatial region where surveillance is to be conducted which is at least a portion of the spatial region or a time slot when surveillance is to be conducted, from among the spatial region and the time slot indicated by the high-risk time and space information, on the basis of the information of theType: ApplicationFiled: November 6, 2023Publication date: February 29, 2024Applicant: NEC CorporationInventors: Junko NAKAGAWA, Ryoma Oami, Kenichiro IDA, Mika Saito, Shohzoh Nagahama, Akinari Furukawa, Yasumasa Ohtsuka, Junichi Fukuda, Fumi Ikeda, Manabu Moriyama, Fumie Einaga, Tatsunori Yamagami, Keisuke Hirayama, Yoshitsugu Kumano, Hiroki Adachi
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Patent number: 11479757Abstract: To reduce the effect of L-proline in the reaction of a sarcosine oxidase. A modified sarcosine oxidase having reduced reactivity to L-proline is provided.Type: GrantFiled: September 13, 2017Date of Patent: October 25, 2022Assignee: KIKKOMAN CORPORATIONInventors: Eriko Yoshihara, Keisuke Furukawa, Kazuhiko Shimoji
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Publication number: 20190218528Abstract: To reduce the effect of L-proline in the reaction of a sarcosine oxidase. A modified sarcosine oxidase having reduced reactivity to L-proline is provided.Type: ApplicationFiled: September 13, 2017Publication date: July 18, 2019Applicant: KIKKOMAN CORPORATIONInventors: Eriko YOSHIHARA, Keisuke FURUKAWA, Kazuhiko SHIMOJI
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Patent number: 7374918Abstract: An isolated DNA molecule encoding modified sarcosine oxidases having optimal pH, high activity in the slightly acidic range and improved stability and a method for preparing the modified sarcosine oxidases is disclosed.Type: GrantFiled: January 26, 2007Date of Patent: May 20, 2008Assignee: Kikkoman CorporationInventors: Keisuke Furukawa, Naoki Kajiyama
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Publication number: 20070269860Abstract: (1) A modified sarcosine oxidase with improved stability in the acidic range compared to a wild-type sarcosine oxidase. (2) A sarcosine oxidase gene encoding a modified sarcosine oxidase of the following (a), (b), or (c): (a) protein composed of the amino acid sequence represented by SEQ ID NO: 1 (b) protein composed of an amino acid sequence wherein one or some amino acid(s) are deleted, substituted, or added from the amino acid sequence represented by SEQ ID NO: 1, and which has sarcosine oxidase activity (c) protein composed of an amino acid sequence which shows 80% or more homology to the amino acid sequence represented by SEQ ID NO: 1, and which has sarcosine oxidase activity According to the present invention, sarcosine oxidases, in particular sarcosine oxidases which show optimal pH and high activity in the slightly acidic range and have improved stability can be prepared efficiently, thus making the invention industrially useful.Type: ApplicationFiled: January 26, 2007Publication date: November 22, 2007Applicant: Kikkoman CorporationInventors: Keisuke FURUKAWA, Naoki Kajiyama
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Patent number: 7189548Abstract: (1) A modified sarcosine oxidase with improved stability in the acidic range compared to a wild-type sarcosine oxidase. (2) A sarcosine oxidase gene encoding a modified sarcosine oxidase of the following (a), (b), or (c): (a) protein composed of the amino acid sequence represented by SEQ ID NO: 1 (b) protein composed of an amino acid sequence wherein one or some amino acid(s) are deleted, substituted, or added from the amino acid sequence represented by SEQ ID NO: 1, and which has sarcosine oxidase activity (c) protein composed of an amino acid sequence which shows 80% or more homology to the amino acid sequence represented by SEQ ID NO: 1, and which has sarcosine oxidase activity According to the present invention, sarcosine oxidases, in particular sarcosine oxidases which show optimal pH and high activity in the slightly acidic range and have improved stability can be prepared efficiently, thus making the invention industrially useful.Type: GrantFiled: April 22, 2004Date of Patent: March 13, 2007Assignee: Kikkoman CorporationInventors: Keisuke Furukawa, Naoki Kajiyama
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Patent number: 7132253Abstract: A modified sarcosine oxidase having a lowered activity for N-ethylglycine. Such a modified oxidase may have the following physicochemical properties: (a) action: hydrolyzes 1 mol of sarcosine to produce 1 mol of glycine and 1 mol of formaldehyde; (b) substrate specificity: reactivity for N-ethylglycine is 70% or less compared with that of an unmodified protein; (c) optimal pH: around 8.0; (d) stable pH range: between 6.5 and 11.0; (e) optimal temperature: 55° C.; (f) thermostability: 55° C. or less; and (g) molecular weight: approximately 43,000 (SDS-PAGE). Genes, vectors and host cells encoding or expressing modified sarcosine oxidases. The modified sarcosine oxidases of the present invention can be used as reagents for measuring creatinine or creatine. The reagents containing the modified sarcosine oxidases used therein are hardly affected by N-ethylglycine, enabling more precise measurement than ever before.Type: GrantFiled: November 18, 2004Date of Patent: November 7, 2006Assignee: Kikkoman CorporationInventors: Keisuke Furukawa, Naoki Kajiyama
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Publication number: 20050287624Abstract: A modified sarcosine oxidase having a lowered activity for N-ethylglycine. Such a modified oxidase may have the following physicochemical properties: (a) action: hydrolyzes 1 mol of sarcosine to produce 1 mol of glycine and 1 mol of formaldehyde; (b) substrate specificity: reactivity for N-ethylglycine is 70% or less compared with that of an unmodified protein; (c) optimal pH: around 8.0; (d) stable pH range: between 6.5 and 11.0; (e) optimal temperature: 55° C.; (f) thermostability: 55° C. or less; and (g) molecular weight: approximately 43,000 (SDS-PAGE). Genes, vectors and host cells encoding or expressing modified sarcosine oxidases. The modified sarcosine oxidases of the present invention can be used as reagents for measuring creatinine or creatine. The reagents containing the modified sarcosine oxidases used therein are hardly affected by N-ethylglycine, enabling more precise measurement than ever before.Type: ApplicationFiled: November 18, 2004Publication date: December 29, 2005Applicant: Kikkoman CorporationInventors: Keisuke Furukawa, Naoki Kajiyama
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Publication number: 20050026265Abstract: (1) A modified sarcosine oxidase with improved stability in the acidic range compared to a wild-type sarcosine oxidase. (2) A sarcosine oxidase gene encoding a modified sarcosine oxidase of the following (a), (b), or (c): (a) protein composed of the amino acid sequence represented by SEQ ID NO: 1 (b) protein composed of an amino acid sequence wherein one or some amino acid(s) are deleted, substituted, or added from the amino acid sequence represented by SEQ ID NO: 1, and which has sarcosine oxidase activity (c) protein composed of an amino acid sequence which shows 80% or more homology to the amino acid sequence represented by SEQ ID NO: 1, and which has sarcosine oxidase activity According to the present invention, sarcosine oxidases, in particular sarcosine oxidases which show optimal pH and high activity in the slightly acidic range and have improved stability can be prepared efficiently, thus making the invention industrially useful.Type: ApplicationFiled: April 22, 2004Publication date: February 3, 2005Applicant: Kikkoman CorporationInventors: Keisuke Furukawa, Naoki Kajiyama
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Patent number: 6821766Abstract: The present invention relates to a thermostable creatine amidinohydrolase having the following physicochemical properties: (a) hydrolyzing 1 mol of creatine to give 1 mol of sarcosine and 1 mol of urea; (b) having a substrate specificity to creatine; (c) having an optimum pH of 7.0 to 8.0; (d) having a stable pH range of 4.0 to 11.0; (e) having the optimum temperature of around 45° C.; (f) being thermostable at 53° C.; (g) having a molecular weight of 92,000 Da (as determined by gel filtration), and to a process for producing the thermostable creatine aimdinohydrolase.Type: GrantFiled: June 27, 2001Date of Patent: November 23, 2004Assignee: Kikkoman CorporationInventors: Keisuke Furukawa, Yasuji Koyama, Masaru Suzuki
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Patent number: 6699700Abstract: The present invention relates to a creatine amidinohydrolase having the following physicochemical properties: (a) hydrolyzing 1 mole of creatine to generate 1 mole of sarcosine and 1 mole of urea, (b) having a substrate specificity to creatine, (c) having an optimum pH ranging from 6.0 to 7.0, particularly a pH of about 6.5, (d) having a stable pH ranging from 4.0 to 11.0, (e) having an optimum temperature ranging from 50 to 55° C., and (f) having a molecular weight of approximately 92,000 daltons (as measured by gel filtration); and to a method for producing a creatine amidinohydrolase, which comprises, culturing a microorganism having an ability to produce the creatine amidinohydrolase, and recovering the creatine amidinohydrolase from the obtained culture. The creatine amidinohydrolase of the invention is characterized by being insusceptible to bilirubin when measuring creatinine, since its optimum pH is in the weakly acidic range.Type: GrantFiled: May 24, 2001Date of Patent: March 2, 2004Assignee: Kikkoman CorporationInventors: Keisuke Furukawa, Toshio Ichikawa
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Patent number: 5932466Abstract: The present invention relates to a creatine amidinohydrolase gene coding for the amino acid sequence of SEQ ID NO. 2, a recombinant DNA comprising the creatine amidinohydrolase gene inserted into a vector DNA, and a process for producing creatine amidinohydrolase by culturing a microorganism belonging to the genus Escherichia carrying said recombinant DNA and having the ability to produce creatine amidinohydrolase in medium and then recovering creatine amidinohydrolase from the culture.According to the present invention, creatine amidinohydrolase can be efficiently produced without adding creatine to medium.Type: GrantFiled: October 9, 1997Date of Patent: August 3, 1999Assignee: Kikkoman CorporationInventors: Keisuke Furukawa, Toshio Ichikawa, Masaru Suzuki, Yasuji Koyama
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Patent number: 5451520Abstract: A creatine amidinohydrolase with the following physicochemical properties is prepared:(a) action: hydrolysis of 1 mole of creatine to form 1 mole of sarcosine and 1 mole of urea;(b) substrate specificity: specific for a creatine substrate;(c) optimum pH: 7-9;(d) optimum temperature: around 35.degree.-45.degree. C.;(e) pH stability: stable in the range of pH 5.0-10.5 at 25.degree. C. for 17 hours;(f) thermal stability: stable at a temperature up to about 45.degree. C. at pH 7.5 for 30 min.;(g) inhibitors: AgNO.sub.3, HgCl.sub.2, CuSO.sub.4, etc.; and(h) molecular weight: about 80,000.+-.5000 as determined by gel filtration.The creatine amidinohydrolase is stable in high pH range and possesses a small Km value, so that it can be purified in high pH range resulting in more easy and simple production than the conventional enzyme, and the lower Km value enables reduction in the period of time and in the amount of the enzyme for each measurement.Type: GrantFiled: November 18, 1994Date of Patent: September 19, 1995Assignee: Kikkoman CorporationInventors: Keisuke Furukawa, Kyoko Hashimoto, Masaru Suzuki