Patents by Inventor Keisuke Tamura
Keisuke Tamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240110952Abstract: A current sensor capable of efficiently cooling a busbar by using a cooling device includes a busbar, a shield disposed to face the busbar, a magnetic sensor disposed between the shield and the busbar, and an enclosure that integrally encases part of the busbar, the shield, and the magnetic sensor. When a side on which the busbar is disposed in the X-axis direction in which the busbar, the magnetic sensor, and the shield are arranged is defined as an X1 side, the busbar is disposed on the X1 side from the center line of the enclosure, and at least the X1 side of the enclosure is disposed to face the cooling device.Type: ApplicationFiled: December 14, 2023Publication date: April 4, 2024Inventors: Manabu TAMURA, Keisuke NAKAYAMA, Takahiro TAOKA
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Publication number: 20240102556Abstract: A drive apparatus includes a motor that has a motor shaft extending in an axial direction, a transmission mechanism that is connected on one side in the axial direction of the motor shaft, a lock mechanism that restricts driving of the transmission mechanism, a housing that houses the motor, the transmission mechanism, and the lock mechanism, an oil that is stored in the housing, and an oil passage that circulates the oil. The housing includes a motor room that houses the motor, a gear room that houses the transmission mechanism and the lock mechanism, and a partition that is provided between the motor room and the gear room. The oil passage includes a pump that pumps the oil in the oil passage, a first feed flow passage that feeds the oil to the motor, and a second feed flow passage that feeds the oil to the lock mechanism.Type: ApplicationFiled: December 11, 2023Publication date: March 28, 2024Inventors: Shuhei NAKAMATSU, Shinsuke MIZUKAMI, Tsubasa TAMURA, Keisuke ASO
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Publication number: 20240077493Abstract: Provided is a non-transitory computer-readable medium storing a program for causing a computer to execute the steps including a step of subjecting a sample containing microorganisms to mass spectrometry to obtain a mass spectrum, a step of reading a mass-to-charge ratio m/z of a peak derived from a marker protein from the mass spectrum, and an identification step of identifying which bacteria of serovar of Salmonella genus bacteria the microorganisms contained in the sample contain, based on the mass-to-charge ratio m/z, wherein at least one of two types of ribosomal proteins S8 and Peptidylpropyl isomerase is used as the marker protein.Type: ApplicationFiled: July 13, 2023Publication date: March 7, 2024Applicants: SHIMADZU Corporation, Meijo UniversityInventors: Hiroto Tamura, Naomi Yamamoto, Teruyo Kato, Keisuke Shima, Shinji Funatsu
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Patent number: 10240136Abstract: To provide an improved ?-fructofuranosidase which is capable of efficiently producing kestose while inhibiting the production of nystose. This improved ?-fructofuranosidase comprises either: an amino acid sequence (a) obtained by introducing, into the amino acid sequence represented by SEQ ID NO: 2, an amino acid mutation i) in which the 85th glycine (G) from the N-terminal is substituted for a protein-constituting amino acid other than glycine (G), and/or an amino acid mutation ii) in which the 310th histidine (H) from the N-terminal is substituted for lysine (K), arginine (R), or tyrosine (Y); or an amino acid sequence (b) which exhibits ?-fructofuranosidase activity, and which comprises an amino acid sequence obtained by deleting, substituting, inserting, or adding one or more amino acids in (a) other than the amino acid into which the amino acid mutation has been introduced.Type: GrantFiled: March 10, 2016Date of Patent: March 26, 2019Assignees: B FOOD SCIENCE CO., LTD., MICROBIOPHARM JAPAN CO., LTD.Inventors: Takumi Tochio, Naomi Ito, Saki Nakamura, Yoshimi Fukatani, Tadashi Fujii, Keisuke Tamura
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Patent number: 9963691Abstract: An improved ?-fructofuranosidase is provided. The improved ?-fructofuranosidase may comprise an amino acid sequence having 60% or higher identity to the amino acid sequence of SEQ ID NO: 2, and may contain an amino acid mutation that replaces histidine (H) corresponding to position 395 counted from the N terminus of SEQ ID NO: 2 with arginine (R) or lysine (K), an amino acid mutation that replaces leucine (L) at position 123 counted from the N terminus of SEQ ID NO: 2 with cysteine (C), and/or an amino acid mutation that replaces phenylalanine (F) at position 473 counted from the N terminus of SEQ ID NO: 2 with tyrosine (Y).Type: GrantFiled: December 26, 2014Date of Patent: May 8, 2018Assignees: B FOOD SCIENCE CO., LTD., MICROBIOPHARM JAPAN CO., LTD.Inventors: Takumi Tochio, Saki Nakamura, Misa Yahara, Tadashi Fujii, Keisuke Tamura
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Publication number: 20180044651Abstract: To provide an improved ?-fructofuranosidase which is capable of efficiently producing kestose while inhibiting the production of nystose. This improved ?-fructofuranosidase comprises either: an amino acid sequence (a) obtained by introducing, into the amino acid sequence represented by SEQ ID NO: 2, an amino acid mutation i) in which the 85th glycine (G) from the N-terminal is substituted for a protein-constituting amino acid other than glycine (G), and/or an amino acid mutation ii) in which the 310th histidine (H) from the N-terminal is substituted for lysine (K), arginine (R), or tyrosine (Y); or an amino acid sequence (b) which exhibits ?-fructofuranosidase activity, and which comprises an amino acid sequence obtained by deleting, substituting, inserting, or adding one or more amino acids in (a) other than the amino acid into which the amino acid mutation has been introduced.Type: ApplicationFiled: March 10, 2016Publication date: February 15, 2018Applicants: B FOOD SCIENCE CO., LTD., MICROBIOPHARM JAPAN CO., LTD.Inventors: Takumi TOCHIO, Naomi ITO, Saki NAKAMURA, Yoshimi FUKATANI, Tadashi FUJII, Keisuke TAMURA
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Patent number: 9725748Abstract: [Problem] To provide a production method capable of simply and efficiently producing a fructose-added carbohydrate using ?-fructofuranosidase. [Solution] A method for producing a fructose-added carbohydrate, said method having a step in which a receptor substrate and a hydrate containing terminal fructose residue are brought into contact with: Escherichia coli expressing an anchor protein for expression on a cell surface and ?-fructofuranosidase as one polypeptide, a composition including dead cells of the expressing Escherichia coli, or a polypeptide obtained from the expressing Escherichia coli and including an amino acid sequence of ?-fructofuranosidase.Type: GrantFiled: December 26, 2014Date of Patent: August 8, 2017Assignees: Microbiopharm Japan Co., Ltd., B Food Science Co., Ltd.Inventors: Takumi Tochio, Naomi Ito, Saki Nakamura, Tadashi Fujii, Keisuke Tamura
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Patent number: 9611490Abstract: A method for producing cis-5-hydroxy-L-pipecolic acid is described. A gene recombinant microorganism enabling direct production of cis-5-hydroxy-L-pipecolic acid can be used in the method. Also described is a gene recombinant microorganism. In particular, it is described that a gene recombinant microorganism having DNAs encoding proteins involved in the biosynthesis of L-pipecolic acid and a DNA encoding a protein having the L-pipecolic acid cis-5-hydroxylase activity is cultured in a medium, and cis-5-hydroxy-L-pipecolic acid is collected from the medium.Type: GrantFiled: June 12, 2013Date of Patent: April 4, 2017Assignee: MicroBiopharm Japan Co., Ltd.Inventors: Tadashi Fujii, Keisuke Tamura
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Publication number: 20160319263Abstract: [Problem] To provide an improved ?-fructofuranosidase which enables the production of kestose with high efficiency while reducing the amount of a by-product such as nystose produced during the production of kestose. [Solution] An improved ?-fructofuranosidase comprising an amino acid sequence which is produced by introducing an amino acid mutation into an amino acid sequence for a ?-fructofuranosidase having 60% or higher identity to the amino acid sequence for wild-type ?-fructofuranosidase which is represented by SEQ ID NO: 2, wherein the amino acid mutation is such a mutation that, when amino acid sequence alignment is performed, a histidine (H) residue corresponding to the position 395 as numbered from the N-terminal of the amino acid sequence for the wild-type ? fructofuranosidase which is represented by SEQ ID NO: 2 can be replaced by an arginine (R) residue or a lysine (K) residue.Type: ApplicationFiled: December 26, 2014Publication date: November 3, 2016Applicants: B FOOD SCIENCE CO., LTD., MICROBIOPHARM JAPAN CO., LTD.Inventors: Takumi TOCHIO, Saki NAKAMURA, Misa YAHARA, Tadashi FUJII, Keisuke TAMURA
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Publication number: 20160319316Abstract: [Problem] To provide a production method capable of simply and efficiently producing a fructose-added carbohydrate using ?-fructofuranosidase. [Solution] A method for producing a fructose-added carbohydrate, said method having a step in which a receptor substrate and a hydrate containing terminal fructose residue are brought into contact with: Escherichia coli expressing an anchor protein for expression on a cell surface and ?-fructofuranosidase as one polypeptide, a composition including dead cells of the expressing Escherichia coli, or a polypeptide obtained from the expressing Escherichia coli and including an amino acid sequence of ?-fructofuranosidase.Type: ApplicationFiled: December 26, 2014Publication date: November 3, 2016Applicants: B FOOD SCIENCE CO., LTD, MICROBIOPHARM JAPAN CO., LTDInventors: Takumi TOCHIO, Naomi ITO, Saki NAKAMURA, Tadashi FUJII, Keisuke TAMURA
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Publication number: 20150211035Abstract: A method for producing cis-5-hydroxy-L-pipecolic acid is described. A gene recombinant microorganism enabling direct production of cis-5-hydroxy-L-pipecolic acid can be used in the method. Also described is a gene recombinant microorganism. In particular, it is described that a gene recombinant microorganism having DNAs encoding proteins involved in the biosynthesis of L-pipecolic acid and a DNA encoding a protein having the L-pipecolic acid cis-5-hydroxylase activity is cultured in a medium, and cis-5-hydroxy-L-pipecolic acid is collected from the medium.Type: ApplicationFiled: June 12, 2013Publication date: July 30, 2015Applicant: MicroBiopharm Japan Co., Ltd.Inventors: Tadashi Fujii, Keisuke Tamura
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Patent number: 8369010Abstract: A microscope includes a microscope main unit including a stage on which a specimen is to be placed; and a light source provided on the microscope main unit and emitting illumination light for illuminating the specimen. The microscope also includes a main power supply operable to be turned on and off; a sensor that senses the presence or absence of a subject in a front or side area of the microscope main unit; a determining unit that determines based on a result of the sensing whether the subject moves; and a control unit that turns on the light source when the main power supply is turned on, maintains the light source in an ON state when the determining unit determines that the subject moves, and turns off the light source when the determining unit determines that the subject does not move and a predetermined period of time passes.Type: GrantFiled: November 15, 2010Date of Patent: February 5, 2013Assignee: Olympus CorporationInventors: Masayoshi Karasawa, Keisuke Tamura, Hideaki Endo, Tetsuya Shirota, Tsuyoshi Mochizuki
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Patent number: 8243365Abstract: A microscope includes a main body, a transmitted light source, and a transmitted-light illumination optical system. The main body has a substantially C-shape when viewed from side, and is composed of a lower horizontal portion, an upper horizontal portion, and a brace portion. The brace portion connects between the lower horizontal portion and the upper horizontal portion on their rear side. The transmitted-light illumination optical system brings an illumination light from the transmitted light source to a specimen supported by the main body, and illuminates the specimen with the illumination light transmitted therethrough. The transmitted-light illumination optical system and the transmitted light source are removably attached to the lower horizontal portion of the main body.Type: GrantFiled: August 17, 2009Date of Patent: August 14, 2012Assignee: Olympus CorporationInventors: Atsuhiro Tsuchiya, Keisuke Tamura
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Publication number: 20110058253Abstract: A microscope includes a microscope main unit including a stage on which a specimen is to be placed; and a light source provided on the microscope main unit and emitting illumination light for illuminating the specimen. The microscope also includes a main power supply operable to be turned on and off; a sensor that senses the presence or absence of a subject in a front or side area of the microscope main unit; a determining unit that determines based on a result of the sensing whether the subject moves; and a control unit that turns on the light source when the main power supply is turned on, maintains the light source in an ON state when the determining unit determines that the subject moves, and turns off the light source when the determining unit determines that the subject does not move and a predetermined period of time passes.Type: ApplicationFiled: November 15, 2010Publication date: March 10, 2011Applicant: OLYMPUS CORPORATIONInventors: Masayoshi KARASAWA, Keisuke Tamura, Hideaki Endo, Tetsuya Shirota, Tsuyoshi Mochizuki
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Publication number: 20100053744Abstract: A microscope includes a main body, a transmitted light source, and a transmitted-light illumination optical system. The main body has a substantially C-shape when viewed from side, and is composed of a lower horizontal portion, an upper horizontal portion, and a brace portion. The brace portion connects between the lower horizontal portion and the upper horizontal portion on their rear side. The transmitted-light illumination optical system brings an illumination light from the transmitted light source to a specimen supported by the main body, and illuminates the specimen with the illumination light transmitted therethrough. The transmitted-light illumination optical system and the transmitted light source are removably attached to the lower horizontal portion of the main body.Type: ApplicationFiled: August 17, 2009Publication date: March 4, 2010Applicant: OLYMPUS CORPORATIONInventors: Atsuhiro TSUCHIYA, Keisuke Tamura
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Patent number: 7046437Abstract: A microscope is provided which includes a frame main body having a base portion, an objective lens switching mechanism, a stage, and an ocular lens for observing a specimen image obtained with one of the objective lenses. A rough/fine motion focusing mechanism is disposed rearward of the stage, for moving the objective lens switching mechanism along the observation optical axis in rough motion and fine motion. A first rough motion handle and a first fine motion handle are provided near the rough/fine motion focusing mechanism, for operating the rough/fine motion focusing mechanism. A rough/fine motion focusing operation portion is provided for operating the rough/fine motion focusing mechanism and includes a second rough motion handle and a second fine motion handle provided near a front end of the base portion. And a linkage mechanism is provided for linking the rough/fine motion focusing mechanism with the rough/fine motion focusing operation portion.Type: GrantFiled: May 3, 2005Date of Patent: May 16, 2006Assignee: Olympus Optical Co., LtdInventors: Kenji Karaki, Kazuhiro Hasegawa, Keisuke Tamura
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Patent number: 6992820Abstract: A microscope of the present invention causes laser light emanating from a light source to enter an optical fiber via a laser light introducing mechanism. The exit end of the optical fiber is connected with an adapter having a fiber position adjustment knob. The back focal position of an objective lens and the exit end position of the optical fiber are made conjugate by a condenser lens provided inside a reflecting illumination projecting tube. By shifting the exit end position of the optical fiber, conventional reflecting illumination and evanescent illumination are available.Type: GrantFiled: July 1, 2002Date of Patent: January 31, 2006Assignee: Olympus CorporationInventors: Katsuyuki Abe, Keisuke Tamura
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Patent number: 6940640Abstract: The inverted microscope comprises a microscope main body, a stage configured to place a specimen thereon, a stage fixing part arranged between the stage and the microscope main body and configured to fix the stage to the microscope main body, an objective lens configured to observe the specimen from below the stage, an observation optical system configured to observe a specimen image taken by the objective lens with an eyepiece, and a reflection member configured to reflect an image in vicinity of the objective lens from vicinity of the eyepiece, the reflection member being arranged below the stage fixing part of the microscope main body and arranged on an axis which is almost parallel to an optical axis of the observation optical system passing the eyepiece and passes vicinity of the eyepiece.Type: GrantFiled: February 13, 2003Date of Patent: September 6, 2005Assignee: Olympus Optical Co., Ltd.Inventors: Minoru Sukekawa, Susumu Honda, Atsuhiro Tsuchiya, Miwa Kojima, Keisuke Tamura
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Publication number: 20050190438Abstract: A microscope is provided which includes a frame main body having a base portion, an objective lens switching mechanism, a stage, and an ocular lens for observing a specimen image obtained with one of the objective lenses. A rough/fine motion focusing mechanism is disposed rearward of the stage, for moving the objective lens switching mechanism along the observation optical axis in rough motion and fine motion. A first rough motion handle and a first fine motion handle are provided near the rough/fine motion focusing mechanism, for operating the rough/fine motion focusing mechanism. A rough/fine motion focusing operation portion is provided for operating the rough/fine motion focusing mechanism and includes a second rough motion handle and a second fine motion handle provided near a front end of the base portion. And a linkage mechanism is provided for linking the rough/fine motion focusing mechanism with the rough/fine motion focusing operation portion.Type: ApplicationFiled: May 3, 2005Publication date: September 1, 2005Applicant: OLYMPUS OPTICAL CO., LTDInventors: Kenji Karaki, Kazuhiro Hasegawa, Keisuke Tamura
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Patent number: 6906858Abstract: A rough motion shaft 54 and a fine motion shaft 55 are provided on a front side of a stage 37 with respect to an optical axis of an observation optical system of a microscope. Further, a rough motion shaft 45 and a fine motion shaft 46 are provided on a rear side with respect to the optical axis. The rough motion shaft 54 and the fine motion shaft 55 are linked with the rough motion shaft 45 and the fine motion shaft 46 so as to move objective lenses 43 selectively in rough motion or fine motion. Objective lenses 43A, 43B are arranged in a circular shape on a fixing member 111 and a rotating member 113 rotates objective lenses 43A, 43B along the direction of the arrangement. The rotating member 113 includes a weight 123 that applies a rotation force in an inverse direction.Type: GrantFiled: July 16, 2001Date of Patent: June 14, 2005Assignee: Olympus Optical Co., Ltd.Inventors: Kenji Karaki, Kazuhiro Hasegawa, Keisuke Tamura